Detail Information

Basic Information:


  VIRBase ID:  

HHID00062226

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7a-3p:           CEP120:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7a-3p CEP120
miRBase
Accession/Entrez ID		 MIMAT0004481 153241
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CCDC100//JBTS31//SRTD13

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7a-3p
rs1219969167 chr9:94176028    T/G
rs1399588338 chr9:94176027    G/A
rs1453867589 chr9:94176023    T/A
rs770208205 chr9:94176022    C/T
rs1265084977 chr22:46112817    T/C
rs372596018 chr22:46112808    T/C
rs1198423693 chr9:94176020    A/G
rs748585376 chr9:94176015    A/G
rs781681931 chr9:94176014    T/G
rs972845958 chr9:94176013    CTA/C
rs779353569 chr22:46112805    C/T
rs970921980 chr22:46112807    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CEP120
chr5:122754429(-) A-I      intronic
chr5:122755129(-) A-I      intronic
chr5:122754435(-) A-I      intronic
chr5:122755181(-) A-I      intronic
chr5:122755155(-) A-I      intronic
chr5:122743769(-) A-I      intronic
chr5:122743758(-) A-I      intronic
chr5:122754428(-) A-I      intronic
chr5:122731452(-) A-I      intronic
chr5:122728462(-) A-I      intronic
chr5:122743754(-) A-I      intronic
chr5:122755218(-) A-I      intronic
chr5:122733666(-) A-I      intronic
chr5:122755119(-) A-I      intronic
chr5:122751363(-) A-I      intronic
chr5:122732958(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CEP120
chr5:122742327(-) A-G intron -    22484847
chr5:122732958(-) A-G intron -    22484847
chr5:122733666(-) A-G intron -    22484847
chr5:122745665(-) G-T intron -    22484847
chr5:122755119(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CEP120
chr5:122680675-122680676(-) m6A 3'UTR       27773535
chr5:122680807-122680808(-) m6A 3'UTR       27773535
chr5:122682153-122682154(-) m6A 3'UTR       24981863//27773535//22608085
chr5:122682186-122682187(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr5:122682253-122682254(-) Cm 3'UTR//CDS       -
chr5:122682263-122682264(-) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr5:122682425-122682426(-) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr5:122685640-122685641(-) m6A 3'UTR//CDS       24284625//24981863//27773535//27371828//22608085
chr5:122685680-122685681(-) m6A 3'UTR//CDS       24284625//24981863//27773535//27371828//22608085
chr5:122685720-122685721(-) m6A 3'UTR//CDS       24981863//27773535//22608085
chr5:122685729-122685730(-) m6A 3'UTR//CDS       24981863//27773535//22608085
chr5:122685747-122685748(-) m6A 3'UTR//CDS       24981863//27773535//22608085
chr5:122694015-122694016(-) m6A 3'UTR//intron       27773535
chr5:122694129-122694130(-) m6A 3'UTR//intron       24981863
chr5:122700192-122700193(-) m6A 3'UTR//CDS       24981863
chr5:122700198-122700199(-) m6A 3'UTR//CDS       24981863
chr5:122700207-122700208(-) m6A 3'UTR//CDS       24981863
chr5:122700246-122700247(-) m6A 3'UTR//CDS       24981863
chr5:122700282-122700283(-) m6A 3'UTR//CDS       24981863
chr5:122713085-122713086(-) m6A 3'UTR//CDS       24981863
chr5:122713102-122713103(-) Cm 3'UTR//CDS       -
chr5:122713103-122713104(-) m6A 3'UTR//CDS       24981863
chr5:122713124-122713125(-) m6A 3'UTR//CDS       24981863
chr5:122713143-122713144(-) m6A 3'UTR//CDS       24981863
chr5:122713167-122713168(-) m6A 3'UTR//CDS       24981863
chr5:122713175-122713176(-) m6A 3'UTR//CDS       24981863
chr5:122713185-122713186(-) m6A 3'UTR//CDS       24981863
chr5:122713208-122713209(-) m6A 3'UTR//CDS       24981863
chr5:122714082-122714083(-) m6A 3'UTR//CDS       24981863
chr5:122714092-122714093(-) m6A 3'UTR//CDS       24981863
chr5:122717835-122717836(-) m6A 3'UTR//CDS       24981863
chr5:122717879-122717880(-) m6A 3'UTR//CDS       24981863
chr5:122725752-122725753(-) m6A 3'UTR//CDS       24981863//27773535
chr5:122725804-122725805(-) m6A 3'UTR//CDS       24981863//27773535
chr5:122725815-122725816(-) m6A 3'UTR//CDS       24981863//27773535
chr5:122725908-122725909(-) m6A 3'UTR//intron       27773535
chr5:122725938-122725939(-) m6A 3'UTR//intron       27773535
chr5:122736794-122736795(-) m6A intron       24284625
chr5:122736814-122736815(-) m6A intron       24284625
chr5:122736883-122736884(-) m6A intron       24284625
chr5:122736940-122736941(-) m6A intron       24284625//22575960
chr5:122737098-122737099(-) m6A intron       24284625//22608085
chr5:122737104-122737105(-) m6A intron       24284625//22608085
chr5:122737123-122737124(-) m6A intron       24284625//22608085
chr5:122737266-122737267(-) m6A intron       24284625
chr5:122737272-122737273(-) m6A intron       24284625
chr5:122737290-122737291(-) m6A intron       24284625
chr5:122737314-122737315(-) m6A intron       24284625
chr5:122737507-122737508(-) m6A intron       24284625//27773535//22608085
chr5:122737516-122737517(-) m6A intron       24284625//27773535//22608085
chr5:122737563-122737564(-) m6A intron       24284625//27371828//22608085
chr5:122737580-122737581(-) m6A intron       24284625//24209618//27773535//27371828//22608085
chr5:122737627-122737628(-) m6A intron       24284625//24209618//22608085
chr5:122737676-122737677(-) m6A intron       24284625//22608085
chr5:122737690-122737691(-) m6A intron       24284625
chr5:122737717-122737718(-) m6A intron       24284625
chr5:122737748-122737749(-) m6A intron       24284625
chr5:122738021-122738022(-) m6A intron       24284625
chr5:122758707-122758708(-) m6A 5'UTR//intron       25456834//27773536
chr5:122758740-122758741(-) m6A 5'UTR//intron       25456834//27773536
chr5:122758799-122758800(-) m6A 5'UTR//intron       25456834//27773536
chr5:122758832-122758833(-) m6A 5'UTR//intron       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Extracellular vesicle Colon cancer cell line (LIM1863)     25330373
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
CEP120
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7a-3p
Interactor2: CEP120

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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