Detail Information

Basic Information:


  VIRBase ID:  

HHID00062225

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7a-3p:           PAQR3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7a-3p PAQR3
miRBase
Accession/Entrez ID		 MIMAT0004481 152559
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - RKTG

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7a-3p
rs1219969167 chr9:94176028    T/G
rs1399588338 chr9:94176027    G/A
rs1453867589 chr9:94176023    T/A
rs770208205 chr9:94176022    C/T
rs1265084977 chr22:46112817    T/C
rs372596018 chr22:46112808    T/C
rs1198423693 chr9:94176020    A/G
rs748585376 chr9:94176015    A/G
rs781681931 chr9:94176014    T/G
rs972845958 chr9:94176013    CTA/C
rs779353569 chr22:46112805    C/T
rs970921980 chr22:46112807    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PAQR3
chr4:79839157(-) A-I      3'UTR
chr4:79839152(-) A-I      3'UTR
chr4:79839151(-) A-I      3'UTR
chr4:79839144(-) A-I      3'UTR
chr4:79839143(-) A-I      3'UTR
chr4:79839194(-) A-I      3'UTR
chr4:79839198(-) A-I      3'UTR
chr4:79839158(-) A-I      3'UTR
chr4:79839131(-) A-I      3'UTR
chr4:79814994(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PAQR3
chr4:79832156-79832157(-) m6A 3'UTR//intron       24284625//24981863//27773535//22575960//22608085
chr4:79832263-79832264(-) m6A 3'UTR//intron       24284625//24209618//24981863//22608085
chr4:79832282-79832283(-) m6A 3'UTR//intron       24284625//24209618//24981863//22608085
chr4:79832353-79832354(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr4:79832635-79832636(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085
chr4:79832668-79832669(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085
chr4:79832873-79832874(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr4:79832993-79832994(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr4:79833121-79833122(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr4:79833130-79833131(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr4:79833220-79833221(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085
chr4:79833240-79833241(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085
chr4:79860422-79860423(-) m6A 5'UTR       24209618//27371828//27773536
chr4:79860492-79860493(-) m6A 5'UTR       24209618//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Extracellular vesicle Colon cancer cell line (LIM1863)     25330373
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
PAQR3
Chromatin K562 cells     -
Cytosol K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7a-3p
Interactor2: PAQR3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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