Detail Information

Basic Information:


  VIRBase ID:  

HHID00062169

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7a-3p:           TMX4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7a-3p TMX4
miRBase
Accession/Entrez ID		 MIMAT0004481 56255
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DJ971N18.2//PDIA14//TXNDC13

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7a-3p
rs1219969167 chr9:94176028    T/G
rs1399588338 chr9:94176027    G/A
rs1453867589 chr9:94176023    T/A
rs770208205 chr9:94176022    C/T
rs1265084977 chr22:46112817    T/C
rs372596018 chr22:46112808    T/C
rs1198423693 chr9:94176020    A/G
rs748585376 chr9:94176015    A/G
rs781681931 chr9:94176014    T/G
rs972845958 chr9:94176013    CTA/C
rs779353569 chr22:46112805    C/T
rs970921980 chr22:46112807    A/G

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMX4
chr20:7958386-7958387(-) m6A 3'UTR       24981863//27773535//22608085
chr20:7958494-7958495(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr20:7958537-7958538(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr20:7958575-7958576(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr20:7958595-7958596(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr20:7958617-7958618(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr20:7960750-7960751(-) m6A 3'UTR       27773535
chr20:7960773-7960774(-) m6A 3'UTR       27773535
chr20:7960794-7960795(-) m6A 3'UTR       27773535
chr20:7962088-7962089(-) m6A 3'UTR       24981863//27773535//22608085
chr20:7962116-7962117(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr20:7962148-7962149(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr20:7962221-7962222(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr20:7962248-7962249(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr20:7962577-7962578(-) m6A 3'UTR       24981863//22575960
chr20:7962654-7962655(-) m6A 3'UTR       24981863//22575960
chr20:7962666-7962667(-) m6A 3'UTR       24981863
chr20:7962695-7962696(-) m6A 3'UTR       24981863
chr20:7962862-7962863(-) m6A 3'UTR       24209618//24981863//28052920//26404942//27773535//22608085
chr20:7962903-7962904(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr20:7962943-7962944(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr20:7962991-7962992(-) m1A CDS       26863196
chr20:7963099-7963100(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr20:7963111-7963112(-) m1A CDS       26863196
chr20:7963153-7963154(-) m1A CDS       26863196
chr20:7963174-7963175(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr20:7963180-7963181(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr20:7963186-7963187(-) m1A CDS       26863196
chr20:7963230-7963231(-) m6A CDS       24209618//24981863//27773535//27371828//22608085
chr20:8000340-8000341(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Extracellular vesicle Colon cancer cell line (LIM1863)     25330373
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
TMX4
Chromatin K562 cells     -
Cytosol K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7a-3p
Interactor2: TMX4

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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