Detail Information

Basic Information:


  VIRBase ID:  

HHID00062022

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7a-3p:           CCR7:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7a-3p CCR7
miRBase
Accession/Entrez ID
MIMAT0004481 1236
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BLR2//CC-CKR-7//CCR-7//CD197//CDw197//CMKBR7//EBI1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7a-3p
rs1219969167 chr9:94176028    T/G
rs1399588338 chr9:94176027    G/A
rs1453867589 chr9:94176023    T/A
rs770208205 chr9:94176022    C/T
rs1265084977 chr22:46112817    T/C
rs372596018 chr22:46112808    T/C
rs1198423693 chr9:94176020    A/G
rs748585376 chr9:94176015    A/G
rs781681931 chr9:94176014    T/G
rs972845958 chr9:94176013    CTA/C
rs779353569 chr22:46112805    C/T
rs970921980 chr22:46112807    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CCR7
chr17:38713987(-) A-I      intronic
chr17:38713981(-) A-I      intronic
chr17:38713982(-) A-I      intronic
chr17:38714005(-) A-I      intronic
chr17:38713986(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CCR7
chr17:38710149-38710150(-) m6A 3'UTR       24981863//28052920//27371828
chr17:38710156-38710157(-) m6A 3'UTR       24981863//28052920//27371828
chr17:38710237-38710238(-) m6A 3'UTR       27371828
chr17:38710482-38710483(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710495-38710496(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710510-38710511(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710537-38710538(-) m6A 3'UTR       25456834//24981863//28052920//26404942//27371828
chr17:38710555-38710556(-) m6A 3'UTR       25456834//24981863//28052920//26404942//27371828
chr17:38710574-38710575(-) m6A 3'UTR       25456834//24981863//28052920//26404942//27371828
chr17:38710590-38710591(-) m6A 3'UTR       25456834//24981863//28052920//26404942//27371828
chr17:38710604-38710605(-) m6A 3'UTR       25456834//24981863//28052920//26404942//27371828
chr17:38710623-38710624(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710706-38710707(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710727-38710728(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710734-38710735(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710755-38710756(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710772-38710773(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710796-38710797(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710913-38710914(-) m6A 3'UTR       25456834//24981863//28052920//26404942//27371828
chr17:38710966-38710967(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38710975-38710976(-) m6A 3'UTR       24981863//28052920//26404942//27371828
chr17:38711016-38711017(-) m6A CDS       24981863//28052920//27371828
chr17:38711102-38711103(-) m6A CDS       27371828
chr17:38711819-38711820(-) m6A CDS       28052920//26404942
chr17:38711859-38711860(-) m6A CDS       28052920//26404942
chr17:38711966-38711967(-) m6A 5'UTR//CDS       24284625//24981863//28052920//26404942//27371828
chr17:38712011-38712012(-) m6A 5'UTR//CDS       24284625//24981863//28052920//26404942//27371828
chr17:38712026-38712027(-) m6A 5'UTR//CDS       24284625//24981863//28052920//26404942//27371828
chr17:38715189-38715190(-) m6A 5'UTR//CDS//intron       28052920//27371828
chr17:38716998-38716999(-) m6A 5'UTR//intron       27371828
chr17:38717003-38717004(-) m6A 5'UTR//intron       27371828
chr17:38717013-38717014(-) m6A 5'UTR//intron       27371828
chr17:38717070-38717071(-) m6A 5'UTR//intron       -
chr17:38717106-38717107(-) m6A 5'UTR//intron       -
chr17:38717189-38717190(-) m6A 5'UTR//intron       -
chr17:38717195-38717196(-) m6A 5'UTR//intron       -
chr17:38717227-38717228(-) m6A 5'UTR//intron       -
chr17:38721656-38721657(-) m6A 5'UTR//CDS       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Extracellular vesicle Colon cancer cell line (LIM1863)     25330373
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
CCR7
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7a-3p
Interactor2: CCR7

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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