Basic Information:

  VIRBase ID:  

HHID00061554

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-671-5p:  MIMAT0003880          RAB12:  NM_001025300     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-671-5p	RAB12
miRBase Accession/Entrez ID	MIMAT0003880	201475
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-671-5p	rs1212870175 chr7:151238464    G/A rs1245446101 chr7:151238466    C/T rs1257851000 chr7:151238457    C/G rs750574811 chr7:151238462    G/A rs750574811 chr7:151238462    G/C rs1205917417 chr7:151238456    C/CCTGGAGGGG rs1217223722 chr7:151238456    C/T rs1296629596 chr7:151238450    G/A rs767628930 chr7:151238451    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RAB12	chr18:8632185(+) A-I      intronic chr18:8632047(+) A-I      intronic chr18:8619887(+) A-I      intronic chr18:8618637(+) A-I      intronic chr18:8614714(+) A-I      intronic chr18:8614764(+) A-I      intronic chr18:8630961(+) A-I      intronic chr18:8614710(+) A-I      intronic chr18:8632161(+) A-I      intronic chr18:8618561(+) A-I      intronic chr18:8632182(+) A-I      intronic chr18:8631088(+) A-I      intronic chr18:8632046(+) A-I      intronic chr18:8619951(+) A-I      intronic chr18:8614850(+) A-I      intronic chr18:8619953(+) A-I      intronic chr18:8614683(+) A-I      intronic chr18:8620011(+) A-I      intronic chr18:8619985(+) A-I      intronic chr18:8632196(+) A-I      intronic chr18:8616780(+) A-I      intronic chr18:8619949(+) A-I      intronic chr18:8618625(+) A-I      intronic chr18:8631067(+) A-I      intronic chr18:8614608(+) A-I      intronic chr18:8618588(+) A-I      intronic chr18:8614684(+) A-I      intronic chr18:8632197(+) A-I      intronic chr18:8632011(+) A-I      intronic chr18:8616829(+) A-I      intronic chr18:8631026(+) A-I      intronic chr18:8632102(+) A-I      intronic chr18:8619889(+) A-I      intronic chr18:8632133(+) A-I      intronic chr18:8632051(+) A-I      intronic chr18:8614701(+) A-I      intronic chr18:8618695(+) A-I      intronic chr18:8620113(+) A-I      intronic chr18:8619871(+) A-I      intronic chr18:8631135(+) A-I      intronic chr18:8616909(+) A-I      intronic chr18:8631085(+) A-I      intronic chr18:8614614(+) A-I      intronic chr18:8616911(+) A-I      intronic chr18:8614687(+) A-I      intronic chr18:8619888(+) A-I      intronic chr18:8632018(+) A-I      intronic chr18:8631070(+) A-I      intronic chr18:8616816(+) A-I      intronic chr18:8630986(+) A-I      intronic chr18:8618717(+) A-I      intronic chr18:8616812(+) A-I      intronic chr18:8630980(+) A-I      intronic chr18:8619964(+) A-I      intronic chr18:8620051(+) A-I      intronic chr18:8614773(+) A-I      intronic chr18:8616851(+) A-I      intronic chr18:8632129(+) A-I      intronic chr18:8630967(+) A-I      intronic chr18:8632296(+) A-I      intronic chr18:8619893(+) A-I      intronic chr18:8632084(+) A-I      intronic chr18:8631048(+) A-I      intronic chr18:8632104(+) A-I      intronic chr18:8614767(+) A-I      intronic chr18:8630990(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RAB12	chr18:8614683(+) A-I intron -    21960545 chr18:8614684(+) A-I intron -    21960545 chr18:8616816(+) A-G intron -    22484847 chr18:8616847(+) A-G intron -    22484847 chr18:8616911(+) A-G intron -    22484847 chr18:8619885(+) A-G intron -    22484847 chr18:8619964(+) A-G intron -    22484847 chr18:8620011(+) A-G intron -    22484847 chr18:8631026(+) A-G intron -    22484847 chr18:8632011(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RAB12	chr18:8609525-8609526(+) m6A 5'UTR       24209618 chr18:8609890-8609891(+) m6A CDS       24209618 chr18:8633283-8633284(+) m6A CDS//exon       27773535 chr18:8635576-8635577(+) m6A CDS       24981863//27773535 chr18:8635588-8635589(+) m6A CDS       24981863//27773535 chr18:8638956-8638957(+) m6A 3'UTR       27773535 chr18:8638977-8638978(+) m6A 3'UTR       27773535 chr18:8638994-8638995(+) m6A 3'UTR       27773535 chr18:8639046-8639047(+) m6A 3'UTR       27773535 chr18:8639143-8639144(+) Y 3'UTR       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-671-5p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Exosome B cell line (Raji)|Primary dendritic cells|T cell line (J77)     21505438 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	RAB12	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-671-5p	6-(Bromomethyl)anthracene-1,4-dione 9995010 Drug sensitive Iodine Green 9956454 Drug sensitive 2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive N~4~-(3-Methyl-1h-Indazol-6-Yl)-N~2~-(3,4,5-Trimethoxyphenyl)pyrimidine-2,4-Diamine 9822610 Drug resistant 5-Iodo-8-quinolinol 96111 Drug sensitive Triapine 9571836 Drug sensitive 1-(4-Methoxyphenyl)-3-[(2-oxo-3-indolyl)amino]thiourea 947057 Drug sensitive 1-(2-Thiazolylazo)-2-naphthol 93572 Drug sensitive (3Z,8S,11Z,16S)-8,16-Bis(2-oxopropyl)-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetrone 92973777 Drug sensitive Cyclo[N-methyl-L-alanyl-beta-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl] 91746256 Drug sensitive [(1R,2Z,4R,8R,9R,11R,12S)-1,12-Dihydroxy-2-(hydroxymethyl)-11-methyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] (Z)-2-methylbut-2-enoate 90475906 Drug sensitive [(1R,2S,6R,7R,9S,12S,13S)-13-(Acetyloxymethyl)-12-hydroxy-9-methyl-5-methylidene-4-oxo-3,14-dioxatricyclo[7.4.1.02,6]tetradecan-7-yl] (Z)-2-(acetyloxymethyl)but-2-enoate 90473692 Drug sensitive 3-Piperidino-2-phenylpropiophenone 89341 Drug sensitive 2,5-Dimethyl-1,4-benzoquinone 8718 Drug sensitive Acid Green 27 80837 Drug sensitive Jacaranone 73307 Drug sensitive Redoxal 72571 Drug sensitive Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive 7-Hydroxystaurosporine 72271 Drug sensitive 4-(2-Naphthylamino)phenol 7141 Drug sensitive Lauryl isoquinolinium bromide 7132 Drug sensitive 1-(2-Pyridylazo)-2-naphthol 6825 Drug sensitive Sulbentine 67686 Drug sensitive NO Data IN this field 6711510 Drug sensitive Antineoplastic-301477 6711219 Drug sensitive Reactive Blue 2 656725 Drug sensitive (2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive Vicenistatin 6438888 Drug sensitive 1,3,8-Trihydroxy-6-methoxyanthracene-9,10-dione 636723 Drug resistant Verrucarin A 6326658 Drug sensitive Chalcone analog 6296717 Drug sensitive Daunorubicin hydrochloride 62770 Drug sensitive Irinotecan 60838 Drug sensitive Bizelesin 60794 Drug sensitive Topotecan 60700 Drug sensitive 6-[2-[(2-Methylsulfonylethylamino)methyl]-1,3-thiazol-4-yl]-N-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]quinazolin-4-amine;hydrochloride 57395317 Drug resistant Brequinar 57030 Drug sensitive Cisplatin 5702198 Drug sensitive Teclothiazide potassium 56841138 Drug sensitive Liatris laevigata lactone #2 5477810 Drug sensitive Caracemide 54747 Drug sensitive 7Z-Plakortide H 5472712 Drug sensitive 3-Deazauridine 54684286 Drug sensitive 3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive 9-alpha-Acetoxyparthenolide 54611286 Drug sensitive Tetracarboxyphthalocyanine-Gadolinium 54608636 Drug sensitive p-Chloranilinum[bis(p-chloraniline)dioxalatoruthenate(III)] 54608061 Drug sensitive Stereoisomer of 672120 (MW=262) 5459262 Drug sensitive Betuletol 5459196 Drug sensitive Cuspidatin C 5459164 Drug sensitive Trunculin A 5459125 Drug sensitive Thiram 5455 Drug sensitive Piritrexim isethionate 54368 Drug sensitive (E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive Heliangolide 5384466 Drug sensitive Acetylrolandrolide 5384465 Drug sensitive (1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive Ovatifolin acetate 5358419 Drug sensitive Crassin, acetate 5355441 Drug sensitive MX2 hydrochloride 5351347 Drug sensitive 4-(N-(4-Cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid 53388144 Drug sensitive Chaetochromin 53277 Drug sensitive Improsulfan hydrochloride 5284401 Drug sensitive Cyclosporin A 5284373 Drug sensitive Erioflorin acetate 5281443 Drug sensitive Guanosine,3',5'-tripropanoate 5035970 Drug sensitive Kekule 499328 Drug sensitive Pyrimethamine 4993 Drug sensitive Ammonia; dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498559 Drug sensitive Elsinochrome C 495866 Drug sensitive Dioxadet 48858 Drug sensitive 1,4-Phenanthrenedione, 10-(formyloxy)-4b,5,6,7,8,8a,9,10-octahydro-3,9-dihydroxy-4b,8,8-trimethyl-2-(1-methylethyl)-, (4bS,8aS,9S,10S)- 462176 Drug sensitive Melphalan 460612 Drug sensitive Aphidicolin 457964 Drug sensitive Aclarubicin 451415 Drug sensitive Ossirene 451379 Drug sensitive SMA-838 (HCl salt of NSC 188491) 45028430 Drug sensitive BAS100 Monohydrate 45028404 Drug sensitive [(1R,2S,3S,5R,6R,8S,10E,12R,13S,15R,16S,17R,18S)-18-Benzyl-6-hydroxy-6,8,15,16-tetramethyl-7,20-dioxo-4,14-dioxa-19-azapentacyclo[10.8.0.01,17.03,5.013,15]icos-10-en-2-yl] acetate 44559501 Drug sensitive Isopinnatal 44558939 Drug sensitive Justicidin B 442882 Drug sensitive Oxyacanthine 442333 Drug sensitive 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Methyl 4-[4-(dimethylamino)-5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxooxan-2-yl)oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate 438788 Drug sensitive Physalolactone 433866 Drug sensitive Oridonin (thiol adduct OF) 432952 Drug sensitive Di-n-octyl-secalonsaure A 430141 Drug sensitive 10-Hydroxy-5-methoxy-1-(2-methyloxiran-2-yl)-1,2-dihydrofuro[2,3-c]xanthen-6-one 429905 Drug sensitive Mitoxantrone 4212 Drug sensitive N-[p-[[(2,4-Diamino-6-quinazolinyl)methyl]amino]benzoyl]-L-aspartic acid 419263 Drug sensitive S-(Diisopropylarsino)-3-mercapto-1,2-propanediol 406478 Drug sensitive 4-(4'-Hydroxyphenyl)diazenylbenzenesulfonamide 404195 Drug sensitive Loratadine 3957 Drug sensitive Lomustine 3950 Drug sensitive 2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive Sjg-136 393111 Drug sensitive Leflunomide 3899 Drug sensitive beta-Lapachone 3885 Drug sensitive Lapachol 3884 Drug sensitive N-(2-Bromo-5-methoxybenzylidene)-6,7-dimethoxy-1-naphthalenamine 387181 Drug sensitive Pyrimidin-2-amine, 4-(2-hydroxy-4-methoxyphenyl)-6-phenyl- 386505 Drug sensitive 2,5-Bis(3-Amino-2,4,6-trinitrophenyl)-1,3,4-thiadiazole 385374 Drug sensitive Stereoisomer of NSC 674066-O 384359 Drug sensitive 4,5-Dimethyl-11H-pyrido[4,3-a]carbazole 382590 Drug sensitive 4-Azido-2-chloro-3-cyanoquinoline 381915 Drug sensitive 1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive 1-(2-(Hydroxymethyl)-1,3-dioxolan-4-yl)cytosine 381525 Drug sensitive Carquniostatin B 380452 Drug sensitive 2-Amino-5,8-dihydroxy-1,4-naphthoquinone 377209 Drug sensitive Antineoplastic-656904 376224 Drug sensitive 3,8-Dimethyl-1,2-naphthoquinone 373912 Drug sensitive O-Benzylfluorescein benzyl ester 371436 Drug sensitive Sanguilutine pseudobase 371258 Drug sensitive 1,2-Dimethyl-phenothiazone 369387 Drug sensitive 7-Chloro-1-methyl-phenothiazone 369386 Drug sensitive Macrocalyxoformin B (Rabdosia diterpenoids) 367617 Drug sensitive Diselenide, bis(4-methylphenyl) 365239 Drug sensitive Benzoxazole, 2-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]- 364608 Drug sensitive 4-(1-Benzofuran-2-yl)-7-methoxychromen-2-one 364364 Drug resistant 4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive Aplidazole C . TFA 362402 Drug sensitive Discorhabdin C . TFA 362393 Drug sensitive 7,12-Epidioxybenz[a]anthracene, 7,12-dihydro-7-methyl- 362095 Drug sensitive 3-Deazaneplanocin hydrochloride 358176 Drug sensitive 1-Chloro-3-(3-chloropropylsulfonylsulfanyl)propane 355643 Drug sensitive Dolastatin 11 354399 Drug sensitive 5-(4-Azido-3-chlorophenyl)-6-ethylpyrimidine-2,4-diamine 353605 Drug sensitive 2-Isopropenyl-4,6-diphenoxy-1,3,5-triazine 340916 Drug sensitive Trimetrexate glucuronic acid salt 336805 Drug sensitive 4-Selenazolecarboxamide, 2-beta-D-ribofuranosyl- 334706 Drug sensitive Predorine 333830 Drug sensitive 4-Ethyl-6-methoxy-7-(oxiran-2-ylmethoxy)quinazoline 333565 Drug sensitive Bishelenalinyl malonate 330973 Drug sensitive 2,4-Diamino-5-(3-amino-4-chloro-5-nitrophenyl)-6-ethylpyrimidine 327404 Drug sensitive 6-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]-7H-purin-2-amine 3246652 Drug sensitive Dmask 32465 Drug sensitive Hydroxypristimerin 320914 Drug sensitive 8-Trichloromethyldihydroberberine 320713 Drug sensitive 2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive 1,4-Naphthalenedione, 5,8-dihydroxy-2,3-bis(hydroxymethyl)- 313371 Drug sensitive Flurocitabine 3034016 Drug sensitive Daunorubicin 30323 Drug sensitive 1,1-Dimethyl-5-(2-naphthalenyl)dithiobiuret 3004012 Drug sensitive 2,3-Bis(iodomethyl)-6-methoxyquinoxaline 286257 Drug sensitive Quinoxaline, 6-chloro-2,3-bis(iodomethyl)- 286252 Drug sensitive 2-Chloro-5-[4-[2-chloro-4-(4,6-diamino-2,2-dimethyl-1,3,5-triazin-1-yl)phenyl]butyl]benzenesulfonyl fluoride;ethanesulfonic acid 278692 Drug sensitive Dichloroallyl lawsone 277767 Drug sensitive 6-Bromotoyocamycin 270861 Drug sensitive Deoxycamptothecin 266552 Drug sensitive 1-(2-Chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea 26328 Drug sensitive 1H-Benzo[a]carbazole-1,4(11H)-dione, 11-methyl- 261066 Drug sensitive 2,4,6-Trichloro-5-heptylpyrimidine 260791 Drug sensitive 3,6-Dibromophenanthrene-9,10-dione 258450 Drug sensitive 2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive 3-Amino-N-(4-benzylphenyl)-1H-indazole-1-carboxamide 25197651 Drug sensitive 2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide 25023715 Drug resistant 2,4,6-Trichloro-5-ethylpyrimidine 249455 Drug sensitive Hydrazine sulfate 24842 Drug sensitive 9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive Antimycin A3 245869 Drug sensitive Camptothecin 24360 Drug sensitive 1-(3-Diethylarsino-3-thio-2-methyl-1-oxopropyl)-L-proline 24203225 Drug sensitive [(4E,6Z,10Z)-20,22-Dihydroxy-13,14,17-trimethoxy-4,8,10,12,16-pentamethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-9-yl] carbamate 24199492 Drug sensitive Mepacrine mustard dihydrochloride 24180972 Drug sensitive 9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive 7-Fluoro-2-benzoyl-3-trifluoromethylquioxaline 1,4-dioxide 23635154 Drug sensitive 4-[[(8-Hydroxyquinolin-7-yl)-phenylmethyl]amino]benzoic acid 219564 Drug sensitive Amsacrine 2179 Drug sensitive Diethylcarbamodithioic acid, sodium salt 21192315 Drug sensitive Vitamin E acetate 2117 Drug sensitive 4-Chloro-5-(pyridin-2-ylthio)-3H-1,2-dithiole-3-thione 16766538 Drug sensitive 4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive Bismuthine, (acetyloxy)diphenyl- 16683509 Drug sensitive Azaribine 16574 Drug sensitive Arypurine derivatives 16220246 Drug sensitive Trihexyltetradecylphosphonium hexafluorophosphate 16212610 Drug sensitive Trihexyltetradecylphosphonium tetrafluoroborate 16211343 Drug sensitive Dihydrotriazine derivative 160202 Drug sensitive 1,2:5,6-Dianhydrogalactitol 15942827 Drug sensitive (3As,3bR)-3b-hydroxy-3a,5,5-trimethyl-3-methylidene-4H-cyclopenta[a]pentalene-2,6-dione 15699597 Drug sensitive 2,6-Dibenzylidenecyclohexanone 1550330 Drug sensitive (2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive [(1S,2R,3R,4R,6S,8S,9R,10S,11S,13R)-2,8-Diacetyloxy-3,6-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 153274253 Drug sensitive Sulfanilanilide, 4'-(9-acridinylamino)- 148802 Drug sensitive N-[3-[(3-Amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl]-2-[(1S)-18-[(2S)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8,31-bis(1-hydroxyethyl)-26,46-dimethyl-40,43-dimethylidene-6,9,16,23,28,38,41,44,47-nonaoxo-37-propan-2-yl-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecazanonacyclo[23.23.9.329,35.12,5.112,15.119,22.154,57.01,53.032,60]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazole-4-carboxamide 146156820 Drug sensitive 1H-2,10a-Ethanophenanthrene, kaur-16-en-15-one deriv. 146156727 Drug sensitive Methyl 3-bromo-2-(bromomethyl)propionate 140895 Drug sensitive Edelfosine 1392 Drug sensitive Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive Astrazon Orange R 135747272 Drug sensitive C8, Carbonyl prodigiosine 135540857 Drug sensitive Oxanthrazole 135502299 Drug sensitive 5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive 19-Formylgeldanamycin-N',N'-pentamethylenehydrazone 135468238 Drug sensitive 2-Methylpropyl (3Z)-2-oxo-3-[(4-sulfamoylanilino)methylidene]-1H-indole-5-carboxylate 135421141 Drug sensitive Pyrazofurin 135413551 Drug sensitive 8-Azahypoxanthine 135410720 Drug sensitive 3-Nitro-benzoic acid (2-hydroxy-benzylidene)-hydrazide 135408681 Drug sensitive 2-Chloro-3-(2-butoxyethoxy)naphthazarin 135406263 Drug sensitive Mercury, (4-aminophenyl)(6-thioguanosinato-N7,S6)- 135403617 Drug sensitive Inosine dialdehyde 135400916 Drug sensitive Raltitrexed 135400182 Drug sensitive DTIC-Dome 135398738 Drug sensitive (1R,2S,5S,8S,9S,17R,18R,21S,24R,26S,27S)-14-Chloro-5,15-dihydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacos-11-ene-4,10,22,29-tetrone 134715214 Drug sensitive 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-Deoxy-alpha-L-mannopyranosyl)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside 132274946 Drug sensitive Sendanin 12806435 Drug sensitive Terpentecin 127568 Drug sensitive Octadecylphosphocholine 125219 Drug sensitive (1S,3R,7Z,9R,12S,13R,15S)-13-Butan-2-yl-13-hydroxy-3,7,12-trimethyl-10,14,16-trioxatetracyclo[7.5.1.13,6.012,15]hexadeca-5,7-diene-4,11-dione 11972510 Drug sensitive Cytochalasin q 11970174 Drug sensitive Indotecan 11533060 Drug sensitive p-Toluquinone 11122 Drug sensitive Gentian violet 11057 Drug sensitive Acetylenedicarboxamide 10971 Drug sensitive 6-[4-(1-Cyclohexenyl)-1,3-butadiyn-1-yl]-2(2H)-pyranone 10263039 Drug sensitive (7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive (1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive Erigerol 101318126 Drug sensitive [(1S,2S,4Z,8Z,12R,13S)-12-Hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate 100921072 Drug sensitive Cinnoline, 4-nitro-, 1-oxide 100397 Drug sensitive Tocladesine 100299 Drug sensitive 1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant toxin .delta.53l - Drug resistant tp4ek - Drug resistant (1s,2e,4r,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug sensitive (1s,2e,4r,7e,11e)-4-hydroxy-2,7,11-cembratrien-6-one - Drug sensitive (1s,2e,4s,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug sensitive (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-5-(3-methyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole - Drug sensitive 1,1'-biphenyl, 4,4'bis(thiomethyl)- - Drug sensitive 1,6,7,8-tetra-o-phenylcarbamoylcastnospermine - Drug sensitive 1h-1,2,4-triazole, 3-(4-diazo-4h-imidazol-5-yl)- - Drug sensitive 2,2',5,5'-tetrahydroxy-4,4'-dimethylbiphenyl - Drug sensitive 2,4,16-tribromoestra-1,3,5(10)-trien-3-ol-17-one - Drug sensitive 2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive 2-propen-1-one, 3-(2-hydroxyphenyl)-1-phenyl- (9ci) - Drug sensitive 2-propenone, 1,1'-(2,5-pyridinediyl)bis[3-(2-furanyl)- - Drug sensitive 3,19-benzylidine-14-deoxy-11,12-didehydroandrographolide - Drug sensitive 3,3?-(1h-pyrrole-2,5-diyl)bis(5-chloro-1-methyl-1h-indole) - Drug sensitive 3,7-di(trifluoromethyl)-2-furoylquioxaline 1,4-dioxide - Drug sensitive 3,7-di(trifluoromethyl)-2-naftoylquioxaline 1,4-dioxide - Drug sensitive 3-piperidinone, 3,5-bis[(3,4-dichlorophenyl)methylene]- - Drug sensitive 4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive 4'-deoxy-13',17-dinitro-3',4'-epoxy-vincaleukoblastine - Drug sensitive 4-piperidinone, 3,5-bis[(4-fluorophenyl)methylene]-, (e,e)- - Drug sensitive 4-quinazolone, 7-amino-3-(4-methoxyphenyl)-, hydrate - Drug sensitive 5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive 7,10-acetonide of 14-hydroxy 10-deacetyl baccatin iii - Drug sensitive 7h-5,6-dithioleno[4,3-d]uracil - Drug sensitive 9,10-anthracenedione, 1-[(oxiranylmethyl)amino]- - Drug sensitive b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive benzene, 1,1'-[(1,3-butadiene-1,4-diyl)sulfonyl]bis - Drug sensitive benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive c4, carbonyl, ethyl prodigiosine - Drug sensitive cis-2-hydroxymethyl-4-(isocytosin-1'-yl)-1,3-dioxolane - Drug sensitive dimethylarsinothious acid, 2,4-pyrimidinediyl ester - Drug sensitive ethanol, 2-[4-(2,2':6',2-terpyridin-4'-yl)phenoxy]- - Drug sensitive ethyl-2,3-oxido-(5-bromo-2-methoxyphenyl)propionate - Drug sensitive furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive piceatannol, 4,3',5'-trimethyl,1s0 - Drug sensitive propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive pyrido[3',4':4,5]thieno[2,3-g]isoquinoline, 6-methyl- - Drug sensitive salicylaldehyde, 5-bromo- (8ci) - Drug sensitive tellurium, trichloro[1,2-hexanedioato(2-)-o,o']-, ammonium - Drug sensitive tricyclo[4.4.0.0(2,7)]decane-5-one, 4,4-dibromo-2-methyl- - Drug sensitive tris(1,3-diphenylpropane-1,3-dionata)gallium(iii) - Drug sensitive (-)-dactylolide - Drug sensitive [bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive 1-o-benzoylcastanospermine - Drug sensitive 2'-deoxy-2'-methoxycarbonylmethylidine-uridine - Drug sensitive 2'-o-(all trans)-retinoyl-erythromicine a - Drug sensitive 4-bromo-2-(2-hydroxy-3-methyl-3-butenyl)phenol - Drug sensitive 4'-chloro-3-nitro-o-salicylotoluidide - Drug sensitive 5-methoxy camptothecin - Drug sensitive 7-propanoyltaxol - Drug sensitive ambrosin piperidine diadduct di-n-oxide - Drug sensitive Aminocamptothecin - Drug sensitive Aminopterin Derivative - Drug sensitive analog of cc-1065 - Drug sensitive Annamycin Liposomal - Drug sensitive antibiotic a54556 - Drug sensitive antineoplastic-624657 - Drug sensitive antineoplastic-644916 - Drug sensitive antineoplastic-d665839 - Drug sensitive Aphidicoline glycinate - Drug sensitive arylpurine derivatives - Drug sensitive bis(2-nitrophenyl)sulfilimine - Drug sensitive Camptothecin Derivative - Drug sensitive chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive CI-921: amsacrine derivative - Drug sensitive Copper(II) complex with quin as a ligand - Drug sensitive devadarool (erthoxydiol-x) - Drug sensitive erytroxytriol-p - Drug sensitive Indenoisoquinoline derivative - Drug sensitive insulin-methotrexate conjugate - Drug sensitive largomycin f-ii - Drug sensitive merophan - Drug sensitive Methotrexate Derivative - Drug sensitive mitaplatin - Drug sensitive o-linoleoyl-2-butoxy-1-desoamine - Drug sensitive o-linoleoyl-6-d-glucose - Drug sensitive organosulfur compound - Drug sensitive orlistat (usan) - Drug sensitive phosphocitrate penta sodium salt - Drug sensitive pyrazoline derivative - Drug sensitive rh(iii)-amodiaquine - Drug sensitive secafascaplysin - Drug sensitive stereoisomer of nsc 675784-h - Drug sensitive thiadiazines - Drug sensitive thiostrepton (usan) - Drug sensitive trimethyl(phenylthio)stannane - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-671-5p	Gemcitabine 60750 Drug interaction    RC00006650 Diethylstilbestrol 448537 Drug interaction    RC00006654 Microcystin-LR 445434 Drug interaction    RC00006653 Naringin 442428 Drug interaction    RC00006652 Paroxetine 43815 Drug interaction    RC00006649 Carboplatinum 38904 Drug interaction    RC00006648 Paclitaxel 36314 Drug interaction    RC00006647 5-Fluorouracil 3385 Drug interaction    RC00006645 Bromocriptine 31101 Drug interaction    RC00006646 Proanthocyanidin 108065 Drug interaction    RC00006651

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-671-5p	Paclitaxel       36314

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-671-5p
Interactor2: RAB12

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.