Detail Information

Basic Information:


  VIRBase ID:  

HHID00061497

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-363-5p:           HUWE1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-363-5p HUWE1
miRBase
Accession/Entrez ID		 MIMAT0003385 10075
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ARF-BP1//HECTH9//HSPC272//Ib772//LASU1//MRXST//MULE//URE-B1//UREB1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-363-5p
rs1021883203 chrX:134169428    T/C
rs199822597 chrX:134169435    G/A
rs774988958 chrX:134169446    G/A
rs769433936 chrX:134169439    T/C
rs999048524 chrX:134169445    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR HUWE1
chrX:53684358(-) A-I      intronic
chrX:53684335(-) A-I      intronic
chrX:53673343(-) A-I      intronic
chrX:53568682(-) A-I      intronic
chrX:53673222(-) A-I      intronic
chrX:53684418(-) A-I      intronic
chrX:53688172(-) A-I      intronic
chrX:53673193(-) A-I      intronic
chrX:53688255(-) A-I      intronic
chrX:53688260(-) A-I      intronic
chrX:53688243(-) A-I      intronic
chrX:53670446(-) A-I      intronic
chrX:53667236(-) A-I      intronic
chrX:53667177(-) A-I      intronic
chrX:53663459(-) A-I      intronic
chrX:53662336(-) A-I      intronic
chrX:53651456(-) A-I      intronic
chrX:53651452(-) A-I      intronic
chrX:53651398(-) A-I      intronic
chrX:53689798(-) A-I      intronic
chrX:53689874(-) A-I      intronic
chrX:53690210(-) A-I      intronic
chrX:53709188(-) A-I      intronic
chrX:53688078(-) A-I      intronic
chrX:53567525(-) A-I      intronic
chrX:53567522(-) A-I      intronic
chrX:53651395(-) A-I      intronic
chrX:53651377(-) A-I      intronic
chrX:53600535(-) A-I      intronic
chrX:53567509(-) A-I      intronic
chrX:53567469(-) A-I      intronic
chrX:53600517(-) A-I      intronic
chrX:53600435(-) A-I      intronic
chrX:53690301(-) A-I      intronic
chrX:53690341(-) A-I      intronic
chrX:53699391(-) A-I      intronic
chrX:53699392(-) A-I      intronic
chrX:53688189(-) A-I      intronic
chrX:53582607(-) A-I      intronic
chrX:53580514(-) A-I      intronic
chrX:53580376(-) A-I      intronic
chrX:53580323(-) A-I      intronic
chrX:53580306(-) A-I      intronic
chrX:53688160(-) A-I      intronic
chrX:53580197(-) A-I      intronic
chrX:53578667(-) A-I      intronic
chrX:53568472(-) A-I      intronic
chrX:53568447(-) A-I      intronic
chrX:53568433(-) A-I      intronic
chrX:53567517(-) A-I      intronic
chrX:53567460(-) A-I      intronic
chrX:53688153(-) A-I      intronic
chrX:53688127(-) A-I      intronic
chrX:53580242(-) A-I      intronic
chrX:53580228(-) A-I      intronic
chrX:53688121(-) A-I      intronic
chrX:53688252(-) A-I      intronic
chrX:53684432(-) A-I      intronic
chrX:53690405(-) A-I      intronic
chrX:53691037(-) A-I      intronic
chrX:53691102(-) A-I      intronic
chrX:53691133(-) A-I      intronic
chrX:53691165(-) A-I      intronic
chrX:53691172(-) A-I      intronic
chrX:53691184(-) A-I      intronic
chrX:53691187(-) A-I      intronic
chrX:53690348(-) A-I      intronic
chrX:53567294(-) A-I      intronic
chrX:53690359(-) A-I      intronic
chrX:53691271(-) A-I      intronic
chrX:53691289(-) A-I      intronic
chrX:53692942(-) A-I      intronic
chrX:53567382(-) A-I      intronic
chrX:53567418(-) A-I      intronic
chrX:53567427(-) A-I      intronic
chrX:53567458(-) A-I      intronic
chrX:53695147(-) A-I      intronic
chrX:53695168(-) A-I      intronic
chrX:53695334(-) A-I      intronic
chrX:53695349(-) A-I      intronic
chrX:53695374(-) A-I      intronic
chrX:53695382(-) A-I      intronic
chrX:53690367(-) A-I      intronic
chrX:53690380(-) A-I      intronic
chrX:53598531(-) A-I      intronic
chrX:53598505(-) A-I      intronic
chrX:53690404(-) A-I      intronic
chrX:53598380(-) A-I      intronic
chrX:53598368(-) A-I      intronic
chrX:53598327(-) A-I      intronic
chrX:53582608(-) A-I      intronic
chrX:53684370(-) A-I      intronic
chrX:53699310(-) A-I      intronic
chrX:53699390(-) A-I      intronic
chrX:53699486(-) A-I      intronic
chrX:53690284(-) A-I      intronic
chrX:53629909(-) A-I      intronic
chrX:53598510(-) A-I      intronic
chrX:53569058(-) A-I      intronic
chrX:53580695(-) A-I      intronic
chrX:53598355(-) A-I      intronic
chrX:53568708(-) A-I      intronic
chrX:53600294(-) A-I      intronic
chrX:53689810(-) A-I      intronic
chrX:53580241(-) A-I      intronic
chrX:53568775(-) A-I      intronic
chrX:53580658(-) A-I      intronic
chrX:53695230(-) A-I      intronic
chrX:53568364(-) A-I      intronic
chrX:53598528(-) A-I      intronic
chrX:53699503(-) A-I      intronic
chrX:53568759(-) A-I      intronic
chrX:53598518(-) A-I      intronic
chrX:53695352(-) A-I      intronic
chrX:53593389(-) A-I      intronic
chrX:53708129(-) A-I      intronic
chrX:53663579(-) A-I      intronic
chrX:53690355(-) A-I      intronic
chrX:53568678(-) A-I      intronic
chrX:53663592(-) A-I      intronic
chrX:53638836(-) A-I      intronic
chrX:53663611(-) A-I      intronic
chrX:53689803(-) A-I      intronic
chrX:53691156(-) A-I      intronic
chrX:53691047(-) A-I      intronic
chrX:53580255(-) A-I      intronic
chrX:53598433(-) A-I      intronic
chrX:53567465(-) A-I      intronic
chrX:53662549(-) A-I      intronic
chrX:53567428(-) A-I      intronic
chrX:53684387(-) A-I      intronic
chrX:53567560(-) A-I      intronic
chrX:53689804(-) A-I      intronic
chrX:53567463(-) A-I      intronic
chrX:53651218(-) A-I      intronic
chrX:53690343(-) A-I      intronic
chrX:53598516(-) A-I      intronic
chrX:53567508(-) A-I      intronic
chrX:53699487(-) A-I      intronic
chrX:53598486(-) A-I      intronic
chrX:53598354(-) A-I      intronic
chrX:53699356(-) A-I      intronic
chrX:53568383(-) A-I      intronic
chrX:53580604(-) A-I      intronic
chrX:53580375(-) A-I      intronic
chrX:53636075(-) A-I      intronic
chrX:53691280(-) A-I      intronic
chrX:53692944(-) A-I      intronic
chrX:53670439(-) A-I      intronic
chrX:53692842(-) A-I      intronic
chrX:53598369(-) A-I      intronic
chrX:53600486(-) A-I      intronic
chrX:53690384(-) A-I      intronic
chrX:53662409(-) A-I      intronic
chrX:53689780(-) A-I      intronic
chrX:53598500(-) A-I      intronic
chrX:53580328(-) A-I      intronic
chrX:53567322(-) A-I      intronic
chrX:53699417(-) A-I      intronic
chrX:53568978(-) A-I      intronic
chrX:53662308(-) A-I      intronic
chrX:53568975(-) A-I      intronic
chrX:53598387(-) A-I      intronic
chrX:53600265(-) A-I      intronic
chrX:53663552(-) A-I      intronic
chrX:53691137(-) A-I      intronic
chrX:53582668(-) A-I      intronic
chrX:53567446(-) A-I      intronic
chrX:53691279(-) A-I      intronic
chrX:53670977(-) A-I      intronic
chrX:53691175(-) A-I      intronic
chrX:53598417(-) A-I      intronic
chrX:53699393(-) A-I      intronic
chrX:53689876(-) A-I      intronic
chrX:53580598(-) A-I      intronic
chrX:53699493(-) A-I      intronic
chrX:53695153(-) A-I      intronic
chrX:53673220(-) A-I      intronic
chrX:53567386(-) A-I      intronic
chrX:53567466(-) A-I      intronic
chrX:53695248(-) A-I      intronic
chrX:53597220(-) A-I      intronic
chrX:53593384(-) A-I      intronic
chrX:53684436(-) A-I      intronic
chrX:53568891(-) A-I      intronic
chrX:53689862(-) A-I      intronic
chrX:53568657(-) A-I      intronic
chrX:53568758(-) A-I      intronic
chrX:53695216(-) A-I      intronic
chrX:53568715(-) A-I      intronic
chrX:53580298(-) A-I      intronic
chrX:53671068(-) A-I      intronic
chrX:53689859(-) A-I      intronic
chrX:53695314(-) A-I      intronic
chrX:53567457(-) A-I      intronic
chrX:53600428(-) A-I      intronic
chrX:53598479(-) A-I      intronic
chrX:53699478(-) A-I      intronic
chrX:53600424(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED HUWE1
chrX:53597074(-) A-I intron -    21960545
chrX:53689876(-) A-I intron -    21960545
chrX:53709188(-) A-I intron -    21960545
chrX:53598510(-) A-G intron -    22484847
chrX:53689804(-) A-G intron -    22484847
chrX:53692842(-) A-G intron -    22484847
chrX:53695352(-) A-G intron -    22484847
chrX:53699356(-) A-G intron -    22484847
chrX:53699417(-) A-G intron -    22484847
chrX:53699418(-) A-G intron -    22484847
chrX:53699481(-) A-G intron -    22484847
chrX:53699493(-) A-G intron -    22484847
chrX:53699503(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HUWE1
chrX:53559917-53559918(-) m6A 3'UTR       27773535
chrX:53559924-53559925(-) m6A 3'UTR       27773535
chrX:53559972-53559973(-) m6A 3'UTR       24284625//24209618//24981863//27773535
chrX:53559995-53559996(-) m6A 3'UTR       24284625//24209618//24981863//28052920//27773535
chrX:53560175-53560176(-) m6A 3'UTR       24284625//24209618//24981863//28052920//27773535
chrX:53560196-53560197(-) m6A 3'UTR       24284625//24981863//27773535
chrX:53560224-53560225(-) m6A 3'UTR       24284625//24981863//27773535
chrX:53560761-53560762(-) m6A exon//intron       27773535
chrX:53560775-53560776(-) m6A exon//intron       27773535
chrX:53560795-53560796(-) m6A exon//intron       27773535
chrX:53560857-53560858(-) m6A exon//intron       27773535
chrX:53561110-53561111(-) Y CDS//exon       26075521
chrX:53563363-53563364(-) m6A CDS//exon       24981863
chrX:53564567-53564568(-) m6A CDS//exon       27773535
chrX:53564606-53564607(-) m6A CDS//exon       27773535
chrX:53565333-53565334(-) m6A CDS//exon       27773535//22575960
chrX:53565393-53565394(-) m6A CDS//exon       27773535//22575960
chrX:53565412-53565413(-) m6A CDS//exon       27773535//22575960
chrX:53565968-53565969(-) m6A CDS       24981863//27773535//22575960
chrX:53566651-53566652(-) m6A CDS//exon       22575960
chrX:53566676-53566677(-) m6A CDS//exon       22575960
chrX:53566729-53566730(-) m6A CDS//exon       22575960
chrX:53566761-53566762(-) m6A CDS//exon       22575960
chrX:53569441-53569442(-) m6A 3'UTR//CDS//exon       22575960
chrX:53569690-53569691(-) m6A exon//intron       27773535
chrX:53569739-53569740(-) m6A exon//intron       27773535
chrX:53569795-53569796(-) m6A exon//intron       27773535
chrX:53570819-53570820(-) m6A CDS//exon//intron       22575960
chrX:53571532-53571533(-) m6A CDS//exon//intron       22575960
chrX:53571622-53571623(-) m6A CDS//exon//intron       27773536
chrX:53572059-53572060(-) m6A CDS//exon       22575960
chrX:53574869-53574870(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chrX:53574904-53574905(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chrX:53574913-53574914(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chrX:53574962-53574963(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chrX:53575008-53575009(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chrX:53575052-53575053(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chrX:53575082-53575083(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chrX:53575087-53575088(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chrX:53575100-53575101(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chrX:53575109-53575110(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chrX:53575181-53575182(-) Gm CDS       -
chrX:53575194-53575195(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chrX:53575203-53575204(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chrX:53575952-53575953(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chrX:53576024-53576025(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chrX:53576062-53576063(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chrX:53576145-53576146(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chrX:53576157-53576158(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chrX:53576222-53576223(-) m6A CDS       24284625//24981863//28052920//27371828//22575960//22608085
chrX:53576230-53576231(-) m6A CDS       24284625//24981863//28052920//27371828//22575960//22608085
chrX:53576302-53576303(-) m6A CDS       24284625//22575960
chrX:53576409-53576410(-) m6A CDS       24284625//22575960
chrX:53578010-53578011(-) m6A CDS       22575960
chrX:53578043-53578044(-) m6A CDS       22575960
chrX:53578056-53578057(-) m6A CDS       22575960
chrX:53578076-53578077(-) m6A CDS       22575960
chrX:53578088-53578089(-) m6A CDS       22575960
chrX:53578111-53578112(-) m6A CDS       22575960
chrX:53579601-53579602(-) m6A CDS       27773536
chrX:53584355-53584356(-) m6A CDS       24981863//27773535
chrX:53585631-53585632(-) Gm CDS       -
chrX:53585634-53585635(-) m6A CDS       24981863//27773535
chrX:53585671-53585672(-) m6A CDS       24981863//27773535
chrX:53585690-53585691(-) m6A CDS       24981863//27773535
chrX:53585982-53585983(-) m6A CDS       27773535//22575960
chrX:53586018-53586019(-) m6A CDS       22575960
chrX:53587239-53587240(-) m6A CDS       27773535//22575960
chrX:53587313-53587314(-) m6A CDS       27773535//22575960
chrX:53587373-53587374(-) m6A CDS       24981863//27773535//27371828
chrX:53589150-53589151(-) m6A CDS       24209618//24981863//28052920//27773535//27371828//22575960
chrX:53589180-53589181(-) Am CDS       -
chrX:53589181-53589182(-) Gm CDS       -
chrX:53589186-53589187(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22575960
chrX:53590720-53590721(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22575960
chrX:53590762-53590763(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22575960
chrX:53591590-53591591(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960
chrX:53591632-53591633(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960
chrX:53592032-53592033(-) m6A CDS       24284625//27773535//22575960
chrX:53592089-53592090(-) m6A CDS       27773535//22575960
chrX:53592134-53592135(-) m6A CDS       22575960
chrX:53592153-53592154(-) m6A CDS       22575960
chrX:53595748-53595749(-) m6A CDS       22575960
chrX:53596583-53596584(-) m6A CDS       22575960
chrX:53596719-53596720(-) m6A CDS       22575960
chrX:53596725-53596726(-) m6A CDS       22575960
chrX:53596758-53596759(-) m6A CDS       22575960
chrX:53600852-53600853(-) Cm CDS       -
chrX:53607858-53607859(-) m6A CDS       22575960
chrX:53610646-53610647(-) m6A CDS       22575960
chrX:53610650-53610651(-) Cm CDS       -
chrX:53610674-53610675(-) m6A CDS       22575960
chrX:53610725-53610726(-) m6A CDS       27371828//22575960
chrX:53610819-53610820(-) m6A CDS       24981863//28052920//27773535//27371828//22608085
chrX:53610834-53610835(-) m6A CDS       24981863//28052920//27773535//27371828//22608085
chrX:53610848-53610849(-) m6A CDS       24981863//28052920//27773535//27371828//22608085
chrX:53611209-53611210(-) m6A CDS//exon       24981863//27773535
chrX:53611215-53611216(-) m6A CDS//exon       24981863//27773535
chrX:53611225-53611226(-) m6A CDS//exon       24981863//27773535
chrX:53611285-53611286(-) m6A CDS//intron       27773535//22575960
chrX:53611292-53611293(-) m6A CDS//intron       27773535//22575960
chrX:53612033-53612034(-) m6A CDS//exon       22575960
chrX:53617402-53617403(-) m6A CDS//exon       -
chrX:53617436-53617437(-) m6A CDS//exon       -
chrX:53618032-53618033(-) m6A CDS//exon       22575960
chrX:53618055-53618056(-) m6A CDS//exon       22575960
chrX:53618074-53618075(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chrX:53619387-53619388(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chrX:53619459-53619460(-) m6A CDS//exon       24981863//27773535//22575960
chrX:53619477-53619478(-) m6A CDS//exon       24981863//27773535//22575960
chrX:53619549-53619550(-) m6A CDS//exon       27773535
chrX:53619556-53619557(-) m6A CDS//exon       27773535
chrX:53619565-53619566(-) m6A CDS//exon       27773535
chrX:53622310-53622311(-) m6A CDS//exon       27773535
chrX:53627261-53627262(-) m6A CDS//exon       22575960
chrX:53629576-53629577(-) m6A CDS//exon       22575960
chrX:53630331-53630332(-) m6A CDS//exon       22575960
chrX:53641510-53641511(-) m6A CDS//exon       24981863//27773535
chrX:53654372-53654373(-) m6A CDS//exon       -
chrX:53654406-53654407(-) m6A CDS//exon       -
chrX:53654716-53654717(-) m6A CDS//exon       27773535
chrX:53654801-53654802(-) m6A CDS//exon       27773535
chrX:53654806-53654807(-) m6A CDS//exon       27773535
chrX:53656536-53656537(-) m6A CDS//exon       22575960
chrX:53657848-53657849(-) m6A exon//intron       22575960
chrX:53658565-53658566(-) m6A CDS//exon       27773535
chrX:53658646-53658647(-) m6A exon//intron       27773535
chrX:53661200-53661201(-) m6A CDS//exon       27773535
chrX:53672297-53672298(-) m6A CDS//exon       22575960
chrX:53672329-53672330(-) m6A CDS//exon       22575960
chrX:53707003-53707004(-) Tm 5'UTR//exon       -
chrX:53707601-53707602(-) m6A 5'UTR//intron       27773536
chrX:53713575-53713576(-) m6A 5'UTR//exon       24209618//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-363-5p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Serum     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293)     22984580
HUWE1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm K562 cells     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-363-5p
Interactor2: HUWE1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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