Basic Information:

  VIRBase ID:  

HHID00061339

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-642a-5p:  MIMAT0003312          PEG10:  NM_001184961     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-642a-5p	PEG10
miRBase Accession/Entrez ID	MIMAT0003312	23089
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	EDR//HB-1//Mar2//Mart2//MEF3L//RGAG3//RTL2//SIRH1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-642a-5p	rs1187651627 chr19:45674964    G/GATCCCCCACCCCAA rs1441411829 chr19:45674963    TGGGGTGGGG/T rs775648115 chr19:45674943    G/T rs374751972 chr19:45674950    T/A rs78902025 chr19:45674948    T/G

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PEG10	chr7:94285718-94285719(+) m6A 5'UTR//exon       25456834//24981863 chr7:94285740-94285741(+) m6A 5'UTR//exon       24981863 chr7:94285830-94285831(+) m6A 5'UTR//exon       22575960 chr7:94285853-94285854(+) m6A 5'UTR//exon       24284625 chr7:94292664-94292665(+) m6A 5'UTR//CDS//exon       24284625 chr7:94292901-94292902(+) Gm CDS//intron       - chr7:94292947-94292948(+) m6A CDS//intron       24284625//24981863//26404942//27773535 chr7:94292989-94292990(+) m6A CDS//intron       24284625//24981863//26404942//27773535 chr7:94293014-94293015(+) m6A CDS//intron       24284625//24981863//26404942 chr7:94293109-94293110(+) m6A CDS//intron       24284625//26404942 chr7:94293139-94293140(+) m6A CDS//intron       24284625//26404942 chr7:94293346-94293347(+) m6A CDS//intron       26404942 chr7:94293448-94293449(+) m6A CDS//intron       26404942 chr7:94293745-94293746(+) m6A CDS//intron       26404942//22575960 chr7:94293765-94293766(+) m6A CDS//intron       26404942//22575960 chr7:94293826-94293827(+) m6A CDS//intron       26404942//22575960 chr7:94293850-94293851(+) m6A 3'UTR//CDS//intron       26404942//22575960 chr7:94293946-94293947(+) m6A 3'UTR//CDS//intron       24284625//26404942//22575960 chr7:94294047-94294048(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863//26404942//27773535//22575960 chr7:94294112-94294113(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863//26404942//27773535//22575960 chr7:94294229-94294230(+) Am 3'UTR//CDS//exon//intron       - chr7:94294501-94294502(+) m6A 3'UTR//CDS//intron       26404942 chr7:94294522-94294523(+) m6A 3'UTR//CDS//intron       26404942 chr7:94294636-94294637(+) m6A 3'UTR//CDS//intron       26404942//27773535 chr7:94294668-94294669(+) m6A 3'UTR//CDS//intron       26404942//27773535 chr7:94294722-94294723(+) m6A 3'UTR//CDS//intron       26404942//27773535 chr7:94294778-94294779(+) m6A 3'UTR//CDS//intron       26404942//27773535 chr7:94294849-94294850(+) m6A 3'UTR//CDS//intron       24284625//24981863//26404942//27773535//22575960 chr7:94295150-94295151(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94295178-94295179(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94295319-94295320(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535 chr7:94295438-94295439(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94295487-94295488(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94295567-94295568(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960 chr7:94295583-94295584(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960 chr7:94295653-94295654(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960 chr7:94295669-94295670(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960 chr7:94295707-94295708(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960 chr7:94295723-94295724(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960 chr7:94295827-94295828(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960 chr7:94295932-94295933(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960 chr7:94296103-94296104(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94296179-94296180(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94296211-94296212(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94296231-94296232(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94296372-94296373(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960 chr7:94296386-94296387(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960 chr7:94296455-94296456(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960 chr7:94296498-94296499(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960 chr7:94296594-94296595(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94296669-94296670(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535 chr7:94296791-94296792(+) m6A 3'UTR//intron       26404942 chr7:94296852-94296853(+) m6A 3'UTR//intron       26404942 chr7:94296895-94296896(+) m6A 3'UTR//intron       26404942 chr7:94296945-94296946(+) m6A 3'UTR//intron       26404942 chr7:94296981-94296982(+) m6A 3'UTR//intron       26404942 chr7:94297103-94297104(+) m6A 3'UTR//intron       26404942 chr7:94297127-94297128(+) m6A 3'UTR//intron       26404942 chr7:94297223-94297224(+) m6A 3'UTR//intron       24284625//26404942 chr7:94297386-94297387(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//27773535//22575960 chr7:94297803-94297804(+) m6A 3'UTR//intron       24981863//27773535 chr7:94297855-94297856(+) m6A 3'UTR//intron       24981863//27773535 chr7:94297960-94297961(+) m6A 3'UTR//intron       26404942//27773535 chr7:94297992-94297993(+) m6A 3'UTR//intron       26404942//27773535 chr7:94298037-94298038(+) m6A 3'UTR//intron       26404942//27773535 chr7:94298106-94298107(+) m6A 3'UTR//exon//intron       26404942//27773535 chr7:94298187-94298188(+) m6A 3'UTR//exon//intron       24981863//26404942//27773535 chr7:94298221-94298222(+) m6A 3'UTR//exon//intron       24981863//26404942//27773535 chr7:94298241-94298242(+) m6A 3'UTR//exon//intron       24981863//26404942//27773535 chr7:94298266-94298267(+) m6A 3'UTR//exon//intron       25456834//24981863//26404942//27773535 chr7:94298282-94298283(+) m6A 3'UTR//exon//intron       25456834//24981863//26404942//27773535 chr7:94298312-94298313(+) m6A 3'UTR//exon//intron       25456834//24981863//26404942//27773535 chr7:94298357-94298358(+) m6A 3'UTR//exon//intron       25456834//24981863//26404942//27773535 chr7:94298495-94298496(+) m6A 3'UTR//exon       26404942 chr7:94298573-94298574(+) m6A 3'UTR//exon       26404942//27773535 chr7:94298634-94298635(+) m6A 3'UTR//exon       26404942//27773535 chr7:94298645-94298646(+) m6A 3'UTR//exon       26404942//27773535 chr7:94298656-94298657(+) m6A 3'UTR//exon       26404942//27773535 chr7:94298680-94298681(+) m6A 3'UTR//exon       26404942//27773535 chr7:94298692-94298693(+) m6A 3'UTR//exon       26404942//27773535 chr7:94298777-94298778(+) m6A 3'UTR//exon       24981863//26404942//27773535 chr7:94298833-94298834(+) m6A 3'UTR//exon       24981863//26404942//27773535 chr7:94298877-94298878(+) m6A 3'UTR//exon       24981863//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-642a-5p	Exosome Primary ovarian tumor cells|Serum     18589210 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	PEG10	Cytosol HCC cell line (HepG2)     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)     - Nucleus HCC cell line (HepG2)     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-642a-5p
Interactor2: PEG10

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.