Basic Information:

  VIRBase ID:  

HHID00061135

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-624-5p:  MIMAT0003293          MAX:  NR_073137     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-624-5p	MAX
miRBase Accession/Entrez ID	MIMAT0003293	4149
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	bHLHd4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-624-5p	rs1278140211 chr14:31014716    G/C rs1340440431 chr14:31014712    CA/C rs991440005 chr14:31014714    A/T rs1281278674 chr14:31014726    T/C rs1331954189 chr14:31014720    T/C rs1339745262 chr14:31014723    T/C rs1436307961 chr14:31014714    AGGTACT/A rs778437262 chr14:31014725    C/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAX	chr14:65503099(-) A-I      intronic chr14:65503103(-) A-I      intronic chr14:65503122(-) A-I      intronic chr14:65526624(-) A-I      intronic chr14:65526598(-) A-I      intronic chr14:65525856(-) A-I      intronic chr14:65503123(-) A-I      intronic chr14:65524038(-) A-I      intronic chr14:65521025(-) A-I      intronic chr14:65520995(-) A-I      intronic chr14:65520923(-) A-I      intronic chr14:65518125(-) A-I      intronic chr14:65518117(-) A-I      intronic chr14:65518083(-) A-I      intronic chr14:65518049(-) A-I      intronic chr14:65517146(-) A-I      intronic chr14:65517139(-) A-I      intronic chr14:65503124(-) A-I      intronic chr14:65504067(-) A-I      intronic chr14:65504088(-) A-I      intronic chr14:65504093(-) A-I      intronic chr14:65504699(-) A-I      intronic chr14:65526730(-) A-I      intronic chr14:65526604(-) A-I      intronic chr14:65526727(-) A-I      intronic chr14:65526720(-) A-I      intronic chr14:65526716(-) A-I      intronic chr14:65526690(-) A-I      intronic chr14:65526711(-) A-I      intronic chr14:65526673(-) A-I      intronic chr14:65518785(-) A-I      intronic chr14:65534452(-) A-I      intronic chr14:65504123(-) A-I      intronic chr14:65517126(-) A-I      intronic chr14:65526708(-) A-I      intronic chr14:65534409(-) A-I      intronic chr14:65481383(-) A-I      intronic chr14:65481404(-) A-I      intronic chr14:65481410(-) A-I      intronic chr14:65481432(-) A-I      intronic chr14:65481437(-) A-I      intronic chr14:65514784(-) A-I      intronic chr14:65506906(-) A-I      intronic chr14:65506898(-) A-I      intronic chr14:65506897(-) A-I      intronic chr14:65506895(-) A-I      intronic chr14:65504755(-) A-I      intronic chr14:65504750(-) A-I      intronic chr14:65504729(-) A-I      intronic chr14:65481446(-) A-I      intronic chr14:65503047(-) A-I      intronic chr14:65503051(-) A-I      intronic chr14:65503057(-) A-I      intronic chr14:65503066(-) A-I      intronic chr14:65503069(-) A-I      intronic chr14:65503075(-) A-I      intronic chr14:65503076(-) A-I      intronic chr14:65503083(-) A-I      intronic chr14:65521032(-) A-I      intronic chr14:65521012(-) A-I      intronic chr14:65521006(-) A-I      intronic chr14:65520999(-) A-I      intronic chr14:65520968(-) A-I      intronic chr14:65520963(-) A-I      intronic chr14:65520945(-) A-I      intronic chr14:65520933(-) A-I      intronic chr14:65525838(-) A-I      intronic chr14:65520922(-) A-I      intronic chr14:65520899(-) A-I      intronic chr14:65530359(-) A-I      intronic chr14:65525879(-) A-I      intronic chr14:65527085(-) A-I      intronic chr14:65502770(-) A-I      intronic chr14:65518315(-) A-I      intronic chr14:65518303(-) A-I      intronic chr14:65518217(-) A-I      intronic chr14:65518172(-) A-I      intronic chr14:65518166(-) A-I      intronic chr14:65505373(-) A-I      intronic chr14:65527063(-) A-I      intronic chr14:65518149(-) A-I      intronic chr14:65518071(-) A-I      intronic chr14:65517300(-) A-I      intronic chr14:65527062(-) A-I      intronic chr14:65517257(-) A-I      intronic chr14:65517246(-) A-I      intronic chr14:65527034(-) A-I      intronic chr14:65526770(-) A-I      intronic chr14:65502793(-) A-I      intronic chr14:65517227(-) A-I      intronic chr14:65517226(-) A-I      intronic chr14:65526746(-) A-I      intronic chr14:65526745(-) A-I      intronic chr14:65526725(-) A-I      intronic chr14:65502797(-) A-I      intronic chr14:65526689(-) A-I      intronic chr14:65526680(-) A-I      intronic chr14:65526666(-) A-I      intronic chr14:65502830(-) A-I      intronic chr14:65526648(-) A-I      intronic chr14:65526641(-) A-I      intronic chr14:65502782(-) A-I      intronic chr14:65526628(-) A-I      intronic chr14:65526619(-) A-I      intronic chr14:65524060(-) A-I      intronic chr14:65526590(-) A-I      intronic chr14:65524052(-) A-I      intronic chr14:65522512(-) A-I      intronic chr14:65522507(-) A-I      intronic chr14:65522481(-) A-I      intronic chr14:65522408(-) A-I      intronic chr14:65522405(-) A-I      intronic chr14:65522373(-) A-I      intronic chr14:65526005(-) A-I      intronic chr14:65522372(-) A-I      intronic chr14:65522346(-) A-I      intronic chr14:65505306(-) A-I      intronic chr14:65505353(-) A-I      intronic chr14:65527102(-) A-I      intronic chr14:65525973(-) A-I      intronic chr14:65525967(-) A-I      intronic chr14:65525960(-) A-I      intronic chr14:65525937(-) A-I      intronic chr14:65525885(-) A-I      intronic chr14:65525869(-) A-I      intronic chr14:65525753(-) A-I      intronic chr14:65525752(-) A-I      intronic chr14:65517233(-) A-I      intronic chr14:65524037(-) A-I      intronic chr14:65526019(-) A-I      intronic chr14:65545060(-) A-I      intronic chr14:65524025(-) A-I      intronic chr14:65524015(-) A-I      intronic chr14:65517222(-) A-I      intronic chr14:65522530(-) A-I      intronic chr14:65534498(-) A-I      intronic chr14:65522516(-) A-I      intronic chr14:65533867(-) A-I      intronic chr14:65527090(-) A-I      intronic chr14:65533859(-) A-I      intronic chr14:65533517(-) A-I      intronic chr14:65525844(-) A-I      intronic chr14:65517137(-) A-I      intronic chr14:65522340(-) A-I      intronic chr14:65545084(-) A-I      intronic chr14:65533856(-) A-I      intronic chr14:65533809(-) A-I      intronic chr14:65522331(-) A-I      intronic chr14:65533804(-) A-I      intronic chr14:65521107(-) A-I      intronic chr14:65533691(-) A-I      intronic chr14:65533689(-) A-I      intronic chr14:65521101(-) A-I      intronic chr14:65517116(-) A-I      intronic chr14:65533528(-) A-I      intronic chr14:65533518(-) A-I      intronic chr14:65521056(-) A-I      intronic chr14:65517112(-) A-I      intronic chr14:65533410(-) A-I      intronic chr14:65530562(-) A-I      intronic chr14:65521048(-) A-I      intronic chr14:65530471(-) A-I      intronic chr14:65521046(-) A-I      intronic chr14:65530452(-) A-I      intronic chr14:65517063(-) A-I      intronic chr14:65530447(-) A-I      intronic chr14:65517104(-) A-I      intronic chr14:65521041(-) A-I      intronic chr14:65517069(-) A-I      intronic chr14:65524118(-) A-I      intronic chr14:65524109(-) A-I      intronic chr14:65517057(-) A-I      intronic chr14:65517041(-) A-I      intronic chr14:65515823(-) A-I      intronic chr14:65515819(-) A-I      intronic chr14:65524085(-) A-I      intronic chr14:65515807(-) A-I      intronic chr14:65515806(-) A-I      intronic chr14:65515793(-) A-I      intronic chr14:65515733(-) A-I      intronic chr14:65515619(-) A-I      intronic chr14:65515615(-) A-I      intronic chr14:65514973(-) A-I      intronic chr14:65514910(-) A-I      intronic chr14:65514900(-) A-I      intronic chr14:65514869(-) A-I      intronic chr14:65514838(-) A-I      intronic chr14:65514837(-) A-I      intronic chr14:65514832(-) A-I      intronic chr14:65544987(-) A-I      intronic chr14:65524065(-) A-I      intronic chr14:65514810(-) A-I      intronic chr14:65514773(-) A-I      intronic chr14:65524064(-) A-I      intronic chr14:65514766(-) A-I      intronic chr14:65514743(-) A-I      intronic chr14:65507296(-) A-I      intronic chr14:65507269(-) A-I      intronic chr14:65507266(-) A-I      intronic chr14:65507251(-) A-I      intronic chr14:65505430(-) A-I      intronic chr14:65505400(-) A-I      intronic chr14:65505390(-) A-I      intronic chr14:65524031(-) A-I      intronic chr14:65545095(-) A-I      intronic chr14:65549320(-) A-I      intronic chr14:65534584(-) A-I      intronic chr14:65517187(-) A-I      intronic chr14:65534417(-) A-I      intronic chr14:65534464(-) A-I      intronic chr14:65535053(-) A-I      intronic chr14:65527539(-) A-I      intronic chr14:65534438(-) A-I      intronic chr14:65545344(-) A-I      intronic chr14:65518207(-) A-I      intronic chr14:65533520(-) A-I      intronic chr14:65534468(-) A-I      intronic chr14:65534504(-) A-I      intronic chr14:65518080(-) A-I      intronic chr14:65526620(-) A-I      intronic chr14:65535041(-) A-I      intronic chr14:65525905(-) A-I      intronic chr14:65545098(-) A-I      intronic chr14:65534460(-) A-I      intronic chr14:65517209(-) A-I      intronic chr14:65533356(-) A-I      intronic chr14:65533456(-) A-I      intronic chr14:65534578(-) A-I      intronic chr14:65533460(-) A-I      intronic chr14:65525857(-) A-I      intronic chr14:65557361(-) A-I      intronic chr14:65489901(-) A-I      intronic chr14:65534583(-) A-I      intronic chr14:65535139(-) A-I      intronic chr14:65524047(-) A-I      intronic chr14:65557402(-) A-I      intronic chr14:65526013(-) A-I      intronic chr14:65535031(-) A-I      intronic chr14:65518137(-) A-I      intronic chr14:65534433(-) A-I      intronic chr14:65525833(-) A-I      intronic chr14:65549337(-) A-I      intronic chr14:65525909(-) A-I      intronic chr14:65533485(-) A-I      intronic chr14:65530411(-) A-I      intronic chr14:65525852(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAX	chr14:65542427-65542428(-) m6A 3'UTR//intron       27773535 chr14:65542597-65542598(-) m6A 3'UTR//intron       24284625//24209618//27773535//27371828 chr14:65542640-65542641(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr14:65542710-65542711(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr14:65542756-65542757(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085 chr14:65542771-65542772(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085 chr14:65542889-65542890(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//22608085 chr14:65542905-65542906(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr14:65542937-65542938(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr14:65542943-65542944(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr14:65543034-65543035(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr14:65543098-65543099(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//22608085 chr14:65543110-65543111(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr14:65543165-65543166(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr14:65543260-65543261(-) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//27773535//27371828 chr14:65543320-65543321(-) m6A 3'UTR//CDS//intron       24284625//24209618//27773535//27371828 chr14:65543339-65543340(-) m6A 3'UTR//CDS//intron       24284625//24209618//27773535//27371828 chr14:65543439-65543440(-) m6A 3'UTR//intron       24284625//24209618//27773535//27371828 chr14:65543453-65543454(-) m6A 3'UTR//intron       24284625//24209618//27773535//27371828 chr14:65543462-65543463(-) m6A 3'UTR//intron       24284625//24209618//27773535//27371828 chr14:65543533-65543534(-) m6A 3'UTR//intron       27371828 chr14:65543972-65543973(-) m6A 3'UTR//exon//intron       - chr14:65544405-65544406(-) m6A 3'UTR//exon//intron       27371828 chr14:65544415-65544416(-) m6A 3'UTR//exon//intron       27371828 chr14:65544437-65544438(-) m6A 3'UTR//exon//intron       27371828 chr14:65544458-65544459(-) m6A 3'UTR//exon//intron       27371828 chr14:65544692-65544693(-) m6A 5'UTR//CDS//exon//intron       24981863//27773535 chr14:65544731-65544732(-) m6A 5'UTR//CDS//exon//intron       24981863//27773535 chr14:65550478-65550479(-) m6A 3'UTR//intron       27773535 chr14:65560453-65560454(-) m6A 5'UTR//CDS//exon//intron       27773535 chr14:65560474-65560475(-) m6A 5'UTR//CDS//exon//intron       27773535 chr14:65560486-65560487(-) m6A 5'UTR//CDS//exon//intron       27773535 chr14:65569035-65569036(-) Gm CDS//exon//intron       - chr14:65569148-65569149(-) m6A 5'UTR//exon//intron       24284625//24981863//27773535//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-624-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Plasma     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
	MAX	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HeLa-S3 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-624-5p	Iodine Green 9956454 Drug sensitive Midostaurin 9829523 Drug resistant L-2-Aminobutyric acid 80283 Drug sensitive Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive Sulbentine 67686 Drug sensitive Ixabepilone 6445540 Drug sensitive Verrucarin A 6326658 Drug sensitive Tributyrin 6050 Drug sensitive 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive Artelasticin 5471311 Drug sensitive 3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive Herveline O 5459269 Drug sensitive Cuspidatin C 5459164 Drug sensitive Thiram 5455 Drug sensitive Simvastatin 54454 Drug resistant (1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive Rozex 5353923 Drug sensitive Indanthren Corinth RK 5351878 Drug sensitive Vorinostat 5311 Drug sensitive Spiperone 5265 Drug resistant Kekule 499328 Drug sensitive 10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive Propyl gallate 4947 Drug resistant Tiazofurin 457954 Drug sensitive 1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Di-n-octyl-secalonsaure A 430141 Drug sensitive Cyano pyridine-P-CH3 406496 Drug sensitive S-(Dimethylarsino)-3-mercapto-1,2-propyl dibenzoate 406481 Drug sensitive Aminopyrimidine-CH3 406278 Drug sensitive 2-Amino-4-(2-hydroxy-4-methylphenyl)-5-phenylpyrimidine 392744 Drug sensitive 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive 4-Phenacyloxychromen-2-one 386272 Drug resistant 2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive 2-Ethylaminoestradiol 384235 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant 3,8-Dimethyl-1,2-naphthoquinone 373912 Drug sensitive Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant Maxima isoflavone D 343081 Drug sensitive Antimycin A3 245869 Drug sensitive 5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive Prumycin HCl 24197905 Drug resistant 9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive Drostanolone propionate 224004 Drug sensitive Sudan II 18386 Drug sensitive Astrazon Orange R 135747272 Drug sensitive C8, Carbonyl prodigiosine 135540857 Drug sensitive (2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive Fusariotoxin T-2 102515111 Drug sensitive Chimaphilin 101211 Drug sensitive 6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant 1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant tp4ek - Drug resistant tunicamycin - Drug resistant (z) 3,3',4,5-tetramethoxystilbene - Drug sensitive (z) 4-acetoxy-(3,4',5)-trimethoxystilbene - Drug sensitive 1,4-benzenediamine (9ci), n-butyl-n'-phenyl- - Drug sensitive 1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive 2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive 4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive 4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 4-thiomorpholinecarbodithioic acid, antimony complex - Drug sensitive 7-n,n-dimethylamino brefeldin a hydrochloride - Drug sensitive 9-acridinamine, n-(4-ethoxyphenyl)-, monohydrochloride - Drug sensitive benzamide, 5-bromo-2-hydroxy-n-[3-(trifluoromethyl)phenyl]- - Drug sensitive benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive (Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 2-amino-5-chloro-6-(2-thiazolyloxy)-benzimidazole - Drug sensitive 9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive arylmethylene-f - Drug sensitive his 47-methyl ct - Drug sensitive n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-624-5p
Interactor2: MAX

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.