Basic Information:

  VIRBase ID:  

HHID00061021

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548a-3p:  MIMAT0003251          PALM2AKAP2:  NM_007203     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548a-3p	PALM2AKAP2
miRBase Accession/Entrez ID	MIMAT0003251	445815
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	AKAP-2//AKAP-KL//AKAP2//AKAPKL//MISP2//PALM2//PALM2-AKAP2//PRKA2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548a-3p	rs1164461265 chr6:18571854    A/G rs1165672383 chr6:18571864    G/C rs1367516995 chr6:18571852    G/A rs1452081761 chr6:18571844    C/T rs1456125774 chr6:18571853    C/A rs371324260 chr6:18571856    T/TTAC rs745784846 chr6:18571855    AT/A rs753232100 chr6:18571865    C/T rs765730274 chr6:18571860    T/G rs1029034755 chr6:135239228    G/T rs1178036684 chr6:135239234    A/T rs1395774538 chr6:135239235    C/T rs373439066 chr6:135239231    A/C rs373439066 chr6:135239231    A/G rs1181589874 chr8:104484390    G/T rs1328816266 chr8:104484397    C/T rs552025667 chr8:104484394    T/C rs746672467 chr8:104484389    A/T rs766393197 chr8:104484388    A/G rs769687902 chr8:104484405    G/A rs769687902 chr8:104484405    G/T rs1177955102 chr6:18571847    A/G rs1178800173 chr6:18571851    G/C rs1236087532 chr6:18571849    C/A rs1236087532 chr6:18571849    C/T rs1441316829 chr6:18571850    T/C rs1441316829 chr6:18571850    T/G rs970024181 chr6:18571848    A/T rs1252922886 chr6:135239223    A/T rs1309130208 chr8:104484401    T/A rs1375898875 chr8:104484398    C/G rs745714043 chr8:104484402    T/A rs776399840 chr8:104484399    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PALM2AKAP2	chr9:112781507(+) A-I      intronic chr9:112801043(+) A-I      intronic chr9:112781465(+) A-I      intronic chr9:112801054(+) A-I      intronic chr9:112801100(+) A-I      intronic chr9:112801101(+) A-I      intronic chr9:112801035(+) A-I      intronic chr9:112788460(+) A-I      intronic chr9:112801106(+) A-I      intronic chr9:112781658(+) A-I      intronic chr9:112801444(+) A-I      intronic chr9:112781610(+) A-I      intronic chr9:112780071(+) A-I      intronic chr9:112780115(+) A-I      intronic chr9:112780137(+) A-I      intronic chr9:112801110(+) A-I      intronic chr9:112781670(+) A-I      intronic chr9:112801127(+) A-I      intronic chr9:112804583(+) A-I      intronic chr9:112781470(+) A-I      intronic chr9:112781480(+) A-I      intronic chr9:112801133(+) A-I      intronic chr9:112801033(+) A-I      intronic chr9:112801032(+) A-I      intronic chr9:112801018(+) A-I      intronic chr9:112801470(+) A-I      intronic chr9:112800478(+) A-I      intronic chr9:112800370(+) A-I      intronic chr9:112781499(+) A-I      intronic chr9:112781506(+) A-I      intronic chr9:112800362(+) A-I      intronic chr9:112800345(+) A-I      intronic chr9:112795131(+) A-I      intronic chr9:112795111(+) A-I      intronic chr9:112789293(+) A-I      intronic chr9:112789275(+) A-I      intronic chr9:112789264(+) A-I      intronic chr9:112789248(+) A-I      intronic chr9:112785672(+) A-I      intronic chr9:112785651(+) A-I      intronic chr9:112780242(+) A-I      intronic chr9:112780217(+) A-I      intronic chr9:112780111(+) A-I      intronic chr9:112780108(+) A-I      intronic chr9:112759371(+) A-I      intronic chr9:112718129(+) A-I      intronic chr9:112781676(+) A-I      intronic chr9:112793411(+) A-I      intronic chr9:112809022(+) A-I      intronic chr9:112785675(+) A-I      intronic chr9:112793477(+) A-I      intronic chr9:112794581(+) A-I      intronic chr9:112746025(+) A-I      intronic chr9:112781343(+) A-I      intronic chr9:112800964(+) A-I      intronic chr9:112780740(+) A-I      intronic chr9:112786025(+) A-I      intronic chr9:112781357(+) A-I      intronic chr9:112745986(+) A-I      intronic chr9:112781361(+) A-I      intronic chr9:112781452(+) A-I      intronic chr9:112785723(+) A-I      intronic chr9:112746700(+) A-I      intronic chr9:112780704(+) A-I      intronic chr9:112786117(+) A-I      intronic chr9:112800359(+) A-I      intronic chr9:112781334(+) A-I      intronic chr9:112799537(+) A-I      intronic chr9:112781426(+) A-I      intronic chr9:112795136(+) A-I      intronic chr9:112786138(+) A-I      intronic chr9:112799681(+) A-I      intronic chr9:112798379(+) A-I      intronic chr9:112746030(+) A-I      intronic chr9:112733921(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548a-3p	Exosome Pooled sera     27278097 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Follicular fluid     23666971 Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	PALM2AKAP2	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548a-3p
Interactor2: PALM2AKAP2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.