Detail Information

Basic Information:


  VIRBase ID:  

HHID00061005

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548a-3p:           MEX3C:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548a-3p MEX3C
miRBase
Accession/Entrez ID		 MIMAT0003251 51320
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BM-013//MEX-3C//RKHD2//RNF194

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548a-3p
rs1164461265 chr6:18571854    A/G
rs1165672383 chr6:18571864    G/C
rs1367516995 chr6:18571852    G/A
rs1452081761 chr6:18571844    C/T
rs1456125774 chr6:18571853    C/A
rs371324260 chr6:18571856    T/TTAC
rs745784846 chr6:18571855    AT/A
rs753232100 chr6:18571865    C/T
rs765730274 chr6:18571860    T/G
rs1029034755 chr6:135239228    G/T
rs1178036684 chr6:135239234    A/T
rs1395774538 chr6:135239235    C/T
rs373439066 chr6:135239231    A/C
rs373439066 chr6:135239231    A/G
rs1181589874 chr8:104484390    G/T
rs1328816266 chr8:104484397    C/T
rs552025667 chr8:104484394    T/C
rs746672467 chr8:104484389    A/T
rs766393197 chr8:104484388    A/G
rs769687902 chr8:104484405    G/A
rs769687902 chr8:104484405    G/T
rs1177955102 chr6:18571847    A/G
rs1178800173 chr6:18571851    G/C
rs1236087532 chr6:18571849    C/A
rs1236087532 chr6:18571849    C/T
rs1441316829 chr6:18571850    T/C
rs1441316829 chr6:18571850    T/G
rs970024181 chr6:18571848    A/T
rs1252922886 chr6:135239223    A/T
rs1309130208 chr8:104484401    T/A
rs1375898875 chr8:104484398    C/G
rs745714043 chr8:104484402    T/A
rs776399840 chr8:104484399    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MEX3C
chr18:48707141(-) A-I      intronic
chr18:48706959(-) A-I      intronic
chr18:48706874(-) A-I      intronic
chr18:48705645(-) A-I      intronic
chr18:48705534(-) A-I      intronic
chr18:48705143(-) A-I      intronic
chr18:48705122(-) A-I      intronic
chr18:48711072(-) A-I      intronic
chr18:48705086(-) A-I      intronic
chr18:48705082(-) A-I      intronic
chr18:48705081(-) A-I      intronic
chr18:48706940(-) A-I      intronic
chr18:48711024(-) A-I      intronic
chr18:48705644(-) A-I      intronic
chr18:48705121(-) A-I      intronic
chr18:48707035(-) A-I      intronic
chr18:48705033(-) A-I      intronic
chr18:48705062(-) A-I      intronic
chr18:48705615(-) A-I      intronic
chr18:48705108(-) A-I      intronic
chr18:48705167(-) A-I      intronic
chr18:48704995(-) A-I      intronic
chr18:48705063(-) A-I      intronic
chr18:48705512(-) A-I      intronic
chr18:48705470(-) A-I      intronic
chr18:48705217(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MEX3C
chr18:48702125-48702126(-) m6A 3'UTR       26404942
chr18:48702131-48702132(-) m6A 3'UTR       26404942
chr18:48702485-48702486(-) m6A 3'UTR       26404942
chr18:48702493-48702494(-) m6A 3'UTR       26404942
chr18:48702549-48702550(-) m6A 3'UTR       24981863//26404942//22608085
chr18:48702579-48702580(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr18:48702644-48702645(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085
chr18:48702682-48702683(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr18:48702755-48702756(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr18:48703041-48703042(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr18:48703106-48703107(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:48703158-48703159(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:48703169-48703170(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:48703178-48703179(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:48703228-48703229(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:48703270-48703271(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:48703510-48703511(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//27371828//22608085
chr18:48703596-48703597(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr18:48703634-48703635(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr18:48703671-48703672(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr18:48703721-48703722(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr18:48703777-48703778(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr18:48703792-48703793(-) Y CDS//exon       26075521
chr18:48703898-48703899(-) m6A CDS//exon       24284625//24209618//24981863
chr18:48703916-48703917(-) m6A CDS//exon       24981863
chr18:48723230-48723231(-) m6A CDS//intron       24209618//25456834//24981863//27371828//27773536
chr18:48723280-48723281(-) m6A CDS//intron       24209618//25456834//24981863//27371828//27773536
chr18:48723322-48723323(-) m6A CDS//intron       24209618//25456834//24981863//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548a-3p
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Follicular fluid     23666971
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
MEX3C
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548a-3p
Interactor2: MEX3C

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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