Detail Information

Basic Information:


  VIRBase ID:  

HHID00060995

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548a-3p:           RACK1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548a-3p RACK1
miRBase
Accession/Entrez ID		 MIMAT0003251 10399
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - Gnb2-rs1//GNB2L1//H12.3//HLC-7//PIG21

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548a-3p
rs1164461265 chr6:18571854    A/G
rs1165672383 chr6:18571864    G/C
rs1367516995 chr6:18571852    G/A
rs1452081761 chr6:18571844    C/T
rs1456125774 chr6:18571853    C/A
rs371324260 chr6:18571856    T/TTAC
rs745784846 chr6:18571855    AT/A
rs753232100 chr6:18571865    C/T
rs765730274 chr6:18571860    T/G
rs1029034755 chr6:135239228    G/T
rs1178036684 chr6:135239234    A/T
rs1395774538 chr6:135239235    C/T
rs373439066 chr6:135239231    A/C
rs373439066 chr6:135239231    A/G
rs1181589874 chr8:104484390    G/T
rs1328816266 chr8:104484397    C/T
rs552025667 chr8:104484394    T/C
rs746672467 chr8:104484389    A/T
rs766393197 chr8:104484388    A/G
rs769687902 chr8:104484405    G/A
rs769687902 chr8:104484405    G/T
rs1177955102 chr6:18571847    A/G
rs1178800173 chr6:18571851    G/C
rs1236087532 chr6:18571849    C/A
rs1236087532 chr6:18571849    C/T
rs1441316829 chr6:18571850    T/C
rs1441316829 chr6:18571850    T/G
rs970024181 chr6:18571848    A/T
rs1252922886 chr6:135239223    A/T
rs1309130208 chr8:104484401    T/A
rs1375898875 chr8:104484398    C/G
rs745714043 chr8:104484402    T/A
rs776399840 chr8:104484399    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RACK1
chr5:180667784(-) A-I      intronic
chr5:180669832(-) A-I      intronic
chr5:180669779(-) A-I      intronic
chr5:180669815(-) A-I      intronic
chr5:180667722(-) A-I      intronic
chr5:180669620(-) A-I      intronic
chr5:180669634(-) A-I      intronic
chr5:180669664(-) A-I      intronic
chr5:180669715(-) A-I      intronic
chr5:180669736(-) A-I      intronic
chr5:180669763(-) A-I      intronic
chr5:180667957(-) A-I      ncRNA
chr5:180669695(-) A-I      intronic
chr5:180667912(-) A-I      intronic
chr5:180667894(-) A-I      intronic
chr5:180667778(-) A-I      intronic
chr5:180669834(-) A-I      intronic
chr5:180667800(-) A-I      intronic
chr5:180669666(-) A-I      intronic
chr5:180667733(-) A-I      intronic
chr5:180667404(-) A-I      intronic
chr5:180669786(-) A-I      intronic
chr5:180669772(-) A-I      intronic
chr5:180667966(-) A-I      ncRNA
chr5:180667961(-) A-I      ncRNA
chr5:180668002(-) A-I      ncRNA
chr5:180668041(-) A-I      ncRNA

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548a-3p
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Follicular fluid     23666971
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
RACK1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548a-3p
Interactor2: RACK1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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