Basic Information:

  VIRBase ID:  

HHID00060984

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548a-3p:  MIMAT0003251          PRCC:  NM_005973     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548a-3p	PRCC
miRBase Accession/Entrez ID	MIMAT0003251	5546
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	RCCP1//TPRC

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548a-3p	rs1164461265 chr6:18571854    A/G rs1165672383 chr6:18571864    G/C rs1367516995 chr6:18571852    G/A rs1452081761 chr6:18571844    C/T rs1456125774 chr6:18571853    C/A rs371324260 chr6:18571856    T/TTAC rs745784846 chr6:18571855    AT/A rs753232100 chr6:18571865    C/T rs765730274 chr6:18571860    T/G rs1029034755 chr6:135239228    G/T rs1178036684 chr6:135239234    A/T rs1395774538 chr6:135239235    C/T rs373439066 chr6:135239231    A/C rs373439066 chr6:135239231    A/G rs1181589874 chr8:104484390    G/T rs1328816266 chr8:104484397    C/T rs552025667 chr8:104484394    T/C rs746672467 chr8:104484389    A/T rs766393197 chr8:104484388    A/G rs769687902 chr8:104484405    G/A rs769687902 chr8:104484405    G/T rs1177955102 chr6:18571847    A/G rs1178800173 chr6:18571851    G/C rs1236087532 chr6:18571849    C/A rs1236087532 chr6:18571849    C/T rs1441316829 chr6:18571850    T/C rs1441316829 chr6:18571850    T/G rs970024181 chr6:18571848    A/T rs1252922886 chr6:135239223    A/T rs1309130208 chr8:104484401    T/A rs1375898875 chr8:104484398    C/G rs745714043 chr8:104484402    T/A rs776399840 chr8:104484399    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PRCC	chr1:156757736(+) A-I      intronic chr1:156757862(+) A-I      intronic chr1:156758534(+) A-I      intronic chr1:156757904(+) A-I      intronic chr1:156757902(+) A-I      intronic chr1:156757867(+) A-I      intronic chr1:156757850(+) A-I      intronic chr1:156725892(+) A-I      intronic chr1:156723604(+) A-I      intronic chr1:156757728(+) A-I      intronic chr1:156757723(+) A-I      intronic chr1:156755125(+) A-I      intronic chr1:156755115(+) A-I      intronic chr1:156725924(+) A-I      intronic chr1:156723603(+) A-I      intronic chr1:156725885(+) A-I      intronic chr1:156725882(+) A-I      intronic chr1:156725878(+) A-I      intronic chr1:156758583(+) A-I      intronic chr1:156758535(+) A-I      intronic chr1:156723808(+) A-I      intronic chr1:156758547(+) A-I      intronic chr1:156755721(+) A-I      intronic chr1:156758561(+) A-I      intronic chr1:156725857(+) A-I      intronic chr1:156723847(+) A-I      intronic chr1:156755159(+) A-I      intronic chr1:156723888(+) A-I      intronic chr1:156723905(+) A-I      intronic chr1:156755733(+) A-I      intronic chr1:156723908(+) A-I      intronic chr1:156745255(+) A-I      intronic chr1:156755141(+) A-I      intronic chr1:156723913(+) A-I      intronic chr1:156744482(+) A-I      intronic chr1:156760182(+) A-I      intronic chr1:156755116(+) A-I      intronic chr1:156727111(+) A-I      intronic chr1:156726671(+) A-I      intronic chr1:156723968(+) A-I      intronic chr1:156755185(+) A-I      intronic chr1:156726768(+) A-I      intronic chr1:156725788(+) A-I      intronic chr1:156725793(+) A-I      intronic chr1:156725897(+) A-I      intronic chr1:156760213(+) A-I      intronic chr1:156725965(+) A-I      intronic chr1:156745247(+) A-I      intronic chr1:156744650(+) A-I      intronic chr1:156725972(+) A-I      intronic chr1:156726659(+) A-I      intronic chr1:156727053(+) A-I      intronic chr1:156753352(+) A-I      intronic chr1:156744560(+) A-I      intronic chr1:156753351(+) A-I      intronic chr1:156726724(+) A-I      intronic chr1:156726726(+) A-I      intronic chr1:156744310(+) A-I      intronic chr1:156726664(+) A-I      intronic chr1:156755824(+) A-I      intronic chr1:156757685(+) A-I      intronic chr1:156723756(+) A-I      intronic chr1:156757880(+) A-I      intronic chr1:156757688(+) A-I      intronic chr1:156755183(+) A-I      intronic chr1:156752916(+) A-I      intronic chr1:156757698(+) A-I      intronic chr1:156757727(+) A-I      intronic chr1:156757741(+) A-I      intronic chr1:156723771(+) A-I      intronic chr1:156752875(+) A-I      intronic chr1:156723772(+) A-I      intronic chr1:156752797(+) A-I      intronic chr1:156757753(+) A-I      intronic chr1:156757765(+) A-I      intronic chr1:156726665(+) A-I      intronic chr1:156723807(+) A-I      intronic chr1:156755729(+) A-I      intronic chr1:156727500(+) A-I      intronic chr1:156746072(+) A-I      intronic chr1:156767865(+) A-I      intronic chr1:156767837(+) A-I      intronic chr1:156760364(+) A-I      intronic chr1:156757837(+) A-I      intronic chr1:156745898(+) A-I      intronic chr1:156760355(+) A-I      intronic chr1:156760181(+) A-I      intronic chr1:156745892(+) A-I      intronic chr1:156723825(+) A-I      intronic chr1:156760321(+) A-I      intronic chr1:156755179(+) A-I      intronic chr1:156760311(+) A-I      intronic chr1:156745272(+) A-I      intronic chr1:156726732(+) A-I      intronic chr1:156753328(+) A-I      intronic chr1:156760300(+) A-I      intronic chr1:156760238(+) A-I      intronic chr1:156760234(+) A-I      intronic chr1:156755648(+) A-I      intronic chr1:156755065(+) A-I      intronic chr1:156744557(+) A-I      intronic chr1:156760219(+) A-I      intronic chr1:156753388(+) A-I      intronic chr1:156753373(+) A-I      intronic chr1:156757537(+) A-I      intronic chr1:156755212(+) A-I      intronic chr1:156755270(+) A-I      intronic chr1:156755087(+) A-I      intronic chr1:156752754(+) A-I      intronic chr1:156744365(+) A-I      intronic chr1:156753427(+) A-I      intronic chr1:156726654(+) A-I      intronic chr1:156726649(+) A-I      intronic chr1:156755152(+) A-I      intronic chr1:156767861(+) A-I      intronic chr1:156755255(+) A-I      intronic chr1:156753473(+) A-I      intronic chr1:156755769(+) A-I      intronic chr1:156755086(+) A-I      intronic chr1:156755704(+) A-I      intronic chr1:156760159(+) A-I      intronic chr1:156755140(+) A-I      intronic chr1:156768640(+) A-I      intronic chr1:156757889(+) A-I      intronic chr1:156768562(+) A-I      intronic chr1:156760340(+) A-I      intronic chr1:156760253(+) A-I      intronic chr1:156760336(+) A-I      intronic chr1:156753407(+) A-I      intronic chr1:156760237(+) A-I      intronic chr1:156755049(+) A-I      intronic chr1:156745899(+) A-I      intronic chr1:156745563(+) A-I      intronic chr1:156726648(+) A-I      intronic chr1:156755155(+) A-I      intronic chr1:156760214(+) A-I      intronic chr1:156757848(+) A-I      intronic chr1:156755143(+) A-I      intronic chr1:156760160(+) A-I      intronic chr1:156753395(+) A-I      intronic chr1:156768520(+) A-I      intronic chr1:156723837(+) A-I      intronic chr1:156749382(+) A-I      intronic chr1:156760304(+) A-I      intronic chr1:156760295(+) A-I      intronic chr1:156760404(+) A-I      intronic chr1:156745260(+) A-I      intronic chr1:156745713(+) A-I      intronic chr1:156757724(+) A-I      intronic chr1:156767754(+) A-I      intronic chr1:156757863(+) A-I      intronic chr1:156760268(+) A-I      intronic chr1:156743757(+) A-I      intronic chr1:156760294(+) A-I      intronic chr1:156755657(+) A-I      intronic chr1:156755254(+) A-I      intronic chr1:156760348(+) A-I      intronic chr1:156746101(+) A-I      intronic chr1:156755239(+) A-I      intronic chr1:156760151(+) A-I      intronic chr1:156753266(+) A-I      intronic chr1:156757717(+) A-I      intronic chr1:156743691(+) A-I      intronic chr1:156757769(+) A-I      intronic chr1:156760239(+) A-I      intronic chr1:156755838(+) A-I      intronic chr1:156726774(+) A-I      intronic chr1:156745722(+) A-I      intronic chr1:156758524(+) A-I      intronic chr1:156754013(+) A-I      intronic chr1:156754004(+) A-I      intronic chr1:156757763(+) A-I      intronic chr1:156758593(+) A-I      intronic chr1:156757849(+) A-I      intronic chr1:156767800(+) A-I      intronic chr1:156744490(+) A-I      intronic chr1:156768393(+) A-I      intronic chr1:156760244(+) A-I      intronic chr1:156740306(+) A-I      intronic chr1:156757890(+) A-I      intronic chr1:156755186(+) A-I      intronic chr1:156723764(+) A-I      intronic chr1:156745893(+) A-I      intronic chr1:156757811(+) A-I      intronic chr1:156757751(+) A-I      intronic chr1:156768375(+) A-I      intronic chr1:156767848(+) A-I      intronic chr1:156745575(+) A-I      intronic chr1:156755864(+) A-I      intronic chr1:156755123(+) A-I      intronic chr1:156760423(+) A-I      intronic chr1:156746041(+) A-I      intronic chr1:156745876(+) A-I      intronic chr1:156723370(+) A-I      intronic chr1:156758705(+) A-I      intronic chr1:156755293(+) A-I      intronic chr1:156744227(+) A-I      intronic chr1:156757643(+) A-I      intronic chr1:156755804(+) A-I      intronic chr1:156744542(+) A-I      intronic chr1:156723367(+) A-I      intronic chr1:156755787(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PRCC	chr1:156739540(+) C-G intron -    22484847 chr1:156740306(+) A-G intron -    22484847 chr1:156744542(+) A-G intron -    22484847 chr1:156745260(+) A-G intron -    22484847 chr1:156745575(+) A-G intron -    22484847 chr1:156745893(+) A-G intron -    22484847 chr1:156753395(+) A-G intron -    22484847 chr1:156753407(+) A-G intron -    22484847 chr1:156755087(+) A-G intron -    22484847 chr1:156755123(+) A-G intron -    22484847 chr1:156755140(+) A-G intron -    22484847 chr1:156755186(+) A-G intron -    22484847 chr1:156755212(+) A-G intron -    22484847 chr1:156755255(+) A-G intron -    22484847 chr1:156755657(+) A-G intron -    22484847 chr1:156755769(+) A-G intron -    22484847 chr1:156755864(+) A-G intron -    22484847 chr1:156757537(+) A-G intron -    22484847 chr1:156757717(+) A-G intron -    22484847 chr1:156757811(+) A-G intron -    22484847 chr1:156757848(+) A-G intron -    22484847 chr1:156758705(+) A-G intron -    22484847 chr1:156760237(+) A-G intron -    22484847 chr1:156760239(+) A-G intron -    22484847 chr1:156760268(+) A-G intron -    22484847 chr1:156760304(+) A-G intron -    22484847 chr1:156760340(+) A-G intron -    22484847 chr1:156762279(+) G-A intron -    22484847 chr1:156767800(+) A-G intron -    22484847 chr1:156768520(+) A-G intron -    22484847 chr1:156768562(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PRCC	chr1:156737354-156737355(+) m6A 5'UTR//exon//intron       24284625//24981863//26404942//22608085 chr1:156737451-156737452(+) m6A 5'UTR//intron       24284625//24981863//26404942//22575960//22608085 chr1:156737783-156737784(+) m6A CDS//intron       24284625 chr1:156737883-156737884(+) m6A CDS//intron       24284625 chr1:156752093-156752094(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:156752109-156752110(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:156756414-156756415(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156756448-156756449(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156756465-156756466(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156756503-156756504(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156756539-156756540(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156756552-156756553(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156756558-156756559(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156756706-156756707(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156756803-156756804(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:156760913-156760914(+) m6A CDS//intron       24284625 chr1:156760933-156760934(+) m6A CDS//intron       24284625 chr1:156761522-156761523(+) m6A CDS//exon//intron       24284625 chr1:156764481-156764482(+) m6A CDS//exon       24284625//24981863//27773535 chr1:156764579-156764580(+) m6A CDS//exon       24284625//24981863//27773535 chr1:156765608-156765609(+) m6A exon//intron       24284625//24981863//27773535 chr1:156765633-156765634(+) m6A exon//intron       24284625//24981863//27773535 chr1:156765646-156765647(+) m6A exon//intron       24284625//24981863//27773535 chr1:156765685-156765686(+) m6A exon//intron       24284625//24981863 chr1:156765692-156765693(+) m6A exon//intron       24284625//24981863 chr1:156765714-156765715(+) m6A exon//intron       24284625//24981863 chr1:156767105-156767106(+) m6A CDS//exon       24284625//24209618//24981863 chr1:156770185-156770186(+) m6A CDS//exon       24284625//24209618//24981863//26404942 chr1:156770193-156770194(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22608085 chr1:156770208-156770209(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22608085 chr1:156770228-156770229(+) m6A CDS//exon       24284625//24209618//24981863//22608085 chr1:156770261-156770262(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr1:156770323-156770324(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr1:156770362-156770363(+) m6A 3'UTR//exon       24284625//24981863//22608085 chr1:156770389-156770390(+) m6A 3'UTR//exon       24284625//24981863//22608085 chr1:156770457-156770458(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:156770535-156770536(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:156770566-156770567(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:156770590-156770591(+) m6A 3'UTR//exon       24284625//24981863//22608085 chr1:156770606-156770607(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548a-3p	Exosome Pooled sera     27278097 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Follicular fluid     23666971 Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	PRCC	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548a-3p
Interactor2: PRCC

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.