Detail Information

Basic Information:


  VIRBase ID:  

HHID00060981

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548a-3p:           MBP:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548a-3p MBP
miRBase
Accession/Entrez ID		 MIMAT0003251 4155
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548a-3p
rs1164461265 chr6:18571854    A/G
rs1165672383 chr6:18571864    G/C
rs1367516995 chr6:18571852    G/A
rs1452081761 chr6:18571844    C/T
rs1456125774 chr6:18571853    C/A
rs371324260 chr6:18571856    T/TTAC
rs745784846 chr6:18571855    AT/A
rs753232100 chr6:18571865    C/T
rs765730274 chr6:18571860    T/G
rs1029034755 chr6:135239228    G/T
rs1178036684 chr6:135239234    A/T
rs1395774538 chr6:135239235    C/T
rs373439066 chr6:135239231    A/C
rs373439066 chr6:135239231    A/G
rs1181589874 chr8:104484390    G/T
rs1328816266 chr8:104484397    C/T
rs552025667 chr8:104484394    T/C
rs746672467 chr8:104484389    A/T
rs766393197 chr8:104484388    A/G
rs769687902 chr8:104484405    G/A
rs769687902 chr8:104484405    G/T
rs1177955102 chr6:18571847    A/G
rs1178800173 chr6:18571851    G/C
rs1236087532 chr6:18571849    C/A
rs1236087532 chr6:18571849    C/T
rs1441316829 chr6:18571850    T/C
rs1441316829 chr6:18571850    T/G
rs970024181 chr6:18571848    A/T
rs1252922886 chr6:135239223    A/T
rs1309130208 chr8:104484401    T/A
rs1375898875 chr8:104484398    C/G
rs745714043 chr8:104484402    T/A
rs776399840 chr8:104484399    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MBP
chr18:74828703(-) A-I      intronic
chr18:74825006(-) A-I      intronic
chr18:74738770(-) A-I      intronic
chr18:74739858(-) A-I      intronic
chr18:74738822(-) A-I      intronic
chr18:74713730(-) A-I      intronic
chr18:74713724(-) A-I      intronic
chr18:74711480(-) A-I      intronic
chr18:74825033(-) A-I      intronic
chr18:74824934(-) A-I      intronic
chr18:74739859(-) A-I      intronic
chr18:74828809(-) A-I      intronic
chr18:74824992(-) A-I      intronic
chr18:74825023(-) A-I      intronic
chr18:74713658(-) A-I      intronic
chr18:74713604(-) A-I      intronic
chr18:74739782(-) A-I      intronic
chr18:74825032(-) A-I      intronic
chr18:74733711(-) A-I      intronic
chr18:74825010(-) A-I      intronic
chr18:74769820(-) A-I      intronic
chr18:74824968(-) A-I      intronic
chr18:74713641(-) A-I      intronic
chr18:74824993(-) A-I      intronic
chr18:74711547(-) A-I      intronic
chr18:74824923(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MBP
chr18:74824992(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MBP
chr18:74691252-74691253(-) m6A 3'UTR//exon       27773535
chr18:74691287-74691288(-) m6A 3'UTR//exon       27773535//22575960
chr18:74691441-74691442(-) m6A 3'UTR//exon       22575960
chr18:74691472-74691473(-) m6A 3'UTR//exon       22575960
chr18:74691510-74691511(-) m6A 3'UTR//exon       22575960
chr18:74691541-74691542(-) m6A 3'UTR//exon       22575960
chr18:74691557-74691558(-) m6A 3'UTR//exon       22575960
chr18:74692051-74692052(-) m6A 3'UTR//exon//intron       25456834//22575960
chr18:74692170-74692171(-) m6A 3'UTR//exon//intron       22575960
chr18:74692186-74692187(-) m6A 3'UTR//exon//intron       22575960
chr18:74692194-74692195(-) m6A 3'UTR//exon//intron       22575960
chr18:74725245-74725246(-) m6A 3'UTR//intron       24284625//27773535
chr18:74725312-74725313(-) m6A 3'UTR//intron       27773535
chr18:74725332-74725333(-) m6A 3'UTR//intron       27773535
chr18:74727464-74727465(-) m6A 3'UTR//intron       27773535
chr18:74728302-74728303(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr18:74728310-74728311(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr18:74728442-74728443(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr18:74728502-74728503(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr18:74728536-74728537(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr18:74728700-74728701(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr18:74728720-74728721(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr18:74728860-74728861(-) m6A CDS//exon//intron       24284625//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr18:74728896-74728897(-) m6A CDS//exon//intron       24284625//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr18:74728946-74728947(-) m6A CDS//exon//intron       24284625//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr18:74728995-74728996(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr18:74729008-74729009(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr18:74729037-74729038(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//24981863//27773535//27371828//27773536
chr18:74729052-74729053(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//24981863//27773535//27371828//27773536
chr18:74729148-74729149(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//24981863//27773535//27371828//27773536
chr18:74729181-74729182(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//27773535//27371828//27773536
chr18:74729194-74729195(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//27773535//27371828//27773536
chr18:74729202-74729203(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//27773535//27371828//27773536
chr18:74729208-74729209(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//27773535//27371828//27773536
chr18:74729409-74729410(-) m6A 5'UTR//intron       24284625//27773535//27371828
chr18:74778267-74778268(-) m6A CDS//exon       24981863
chr18:74778280-74778281(-) m6A CDS//exon       24981863
chr18:74778290-74778291(-) m6A CDS//exon       24981863
chr18:74778300-74778301(-) m6A CDS//exon       24981863
chr18:74778331-74778332(-) m6A CDS//exon       24981863
chr18:74792996-74792997(-) Y intron       16381836
chr18:74817209-74817210(-) m6A CDS//exon       27371828//27773536
chr18:74839260-74839261(-) m6A 5'UTR//intron       27371828//27773536
chr18:74844578-74844579(-) m6A 5'UTR//exon//intron       27371828//27773536
chr18:74844619-74844620(-) m6A 5'UTR//exon//intron       25456834//24981863//27371828//27773536
chr18:74844647-74844648(-) m6A 5'UTR//exon//intron       25456834//24981863//27371828//27773536
chr18:74845551-74845552(-) m6A exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548a-3p
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Follicular fluid     23666971
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
MBP
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548a-3p
Interactor2: MBP

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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