Basic Information:

  VIRBase ID:  

HHID00060772

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-580-3p:  MIMAT0003245          DNAJB9:  NM_012328     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-580-3p	DNAJB9
miRBase Accession/Entrez ID	MIMAT0003245	4189
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ERdj4//MDG-1//MDG1//MST049//MSTP049

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-580-3p	rs1277701030 chr5:36147917    C/T rs748870940 chr5:36147915    T/C rs771814640 chr5:36147913    GATTCATC/G rs779426932 chr5:36147912    T/C rs867183932 chr5:36147914    A/T rs894333782 chr5:36147913    G/A rs1211215739 chr5:36147923    T/A rs1258987446 chr5:36147924    C/T rs1372042495 chr5:36147922    T/G rs1485122288 chr5:36147921    A/C

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DNAJB9	chr7:108210035-108210036(+) m6A 5'UTR       24981863//27371828//27773536 chr7:108210371-108210372(+) m6A 5'UTR//exon       24981863 chr7:108213350-108213351(+) m6A CDS//intron       24284625//24981863//27773535//22608085 chr7:108213394-108213395(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22608085 chr7:108213421-108213422(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22608085 chr7:108213486-108213487(+) m6A CDS//intron       24284625//24981863//26404942//27773535//22608085 chr7:108213507-108213508(+) m6A CDS//intron       24284625//24981863//26404942//27773535//22608085 chr7:108213513-108213514(+) m6A CDS//intron       24284625//24981863//26404942//27773535//22608085 chr7:108213551-108213552(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:108213577-108213578(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:108213698-108213699(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:108213737-108213738(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:108213790-108213791(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:108213858-108213859(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:108213872-108213873(+) m6A 3'UTR//intron       24981863//26404942//27773535//22608085 chr7:108213904-108213905(+) m6A 3'UTR//intron       24981863//26404942//27773535//22608085 chr7:108214791-108214792(+) m6A 3'UTR//intron       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-580-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	DNAJB9	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-580-3p
Interactor2: DNAJB9

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.