Detail Information

Basic Information:


  VIRBase ID:  

HHID00060734

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-579-3p:           CCT4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-579-3p CCT4
miRBase
Accession/Entrez ID		 MIMAT0003244 10575
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CCT-DELTA//Cctd//SRB

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-579-3p
rs1165224671 chr5:32394404    T/C
rs1190752232 chr5:32394395    C/T
rs1404190650 chr5:32394401    T/C
rs1412824363 chr5:32394357    AAAGACCATAGACTGTAGTAAGTTGATGCAAAAATAATCGCGG/A
rs1415619084 chr5:32394406    C/T
rs376231726 chr5:32394397    C/T
rs768681140 chr5:32394396    G/A
rs939936972 chr5:32394398    G/A
rs1487016067 chr5:32394410    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CCT4
chr2:62110399(-) A-I      intronic
chr2:62098321(-) A-I      intronic
chr2:62097833(-) A-I      intronic
chr2:62097832(-) A-I      intronic
chr2:62097828(-) A-I      intronic
chr2:62097811(-) A-I      intronic
chr2:62098351(-) A-I      intronic
chr2:62100833(-) A-I      intronic
chr2:62100768(-) A-I      intronic
chr2:62100876(-) A-I      intronic
chr2:62097169(-) A-I      intronic
chr2:62097223(-) A-I      intronic
chr2:62097259(-) A-I      intronic
chr2:62097263(-) A-I      intronic
chr2:62097288(-) A-I      intronic
chr2:62097290(-) A-I      intronic
chr2:62097312(-) A-I      intronic
chr2:62097329(-) A-I      intronic
chr2:62097330(-) A-I      intronic
chr2:62097396(-) A-I      intronic
chr2:62097404(-) A-I      intronic
chr2:62097809(-) A-I      intronic
chr2:62097810(-) A-I      intronic
chr2:62097819(-) A-I      intronic
chr2:62097842(-) A-I      intronic
chr2:62097874(-) A-I      intronic
chr2:62097888(-) A-I      intronic
chr2:62097891(-) A-I      intronic
chr2:62097935(-) A-I      intronic
chr2:62097957(-) A-I      intronic
chr2:62097968(-) A-I      intronic
chr2:62097997(-) A-I      intronic
chr2:62098002(-) A-I      intronic
chr2:62098048(-) A-I      intronic
chr2:62098235(-) A-I      intronic
chr2:62098239(-) A-I      intronic
chr2:62098252(-) A-I      intronic
chr2:62098263(-) A-I      intronic
chr2:62098264(-) A-I      intronic
chr2:62098278(-) A-I      intronic
chr2:62098282(-) A-I      intronic
chr2:62098305(-) A-I      intronic
chr2:62098331(-) A-I      intronic
chr2:62098368(-) A-I      intronic
chr2:62098376(-) A-I      intronic
chr2:62098410(-) A-I      intronic
chr2:62098415(-) A-I      intronic
chr2:62098429(-) A-I      intronic
chr2:62098440(-) A-I      intronic
chr2:62098445(-) A-I      intronic
chr2:62100793(-) A-I      intronic
chr2:62100798(-) A-I      intronic
chr2:62100829(-) A-I      intronic
chr2:62100839(-) A-I      intronic
chr2:62102615(-) A-I      intronic
chr2:62100956(-) A-I      intronic
chr2:62100965(-) A-I      intronic
chr2:62101003(-) A-I      intronic
chr2:62101012(-) A-I      intronic
chr2:62114126(-) A-I      intronic
chr2:62101055(-) A-I      intronic
chr2:62102603(-) A-I      intronic
chr2:62102158(-) A-I      intronic
chr2:62102037(-) A-I      intronic
chr2:62102035(-) A-I      intronic
chr2:62101710(-) A-I      intronic
chr2:62109698(-) A-I      intronic
chr2:62109841(-) A-I      intronic
chr2:62101130(-) A-I      intronic
chr2:62110390(-) A-I      intronic
chr2:62101510(-) A-I      intronic
chr2:62101585(-) A-I      intronic
chr2:62109788(-) A-I      intronic
chr2:62109768(-) A-I      intronic
chr2:62109716(-) A-I      intronic
chr2:62100861(-) A-I      intronic
chr2:62100865(-) A-I      intronic
chr2:62100874(-) A-I      intronic
chr2:62100877(-) A-I      intronic
chr2:62100878(-) A-I      intronic
chr2:62100879(-) A-I      intronic
chr2:62100880(-) A-I      intronic
chr2:62100883(-) A-I      intronic
chr2:62100904(-) A-I      intronic
chr2:62100905(-) A-I      intronic
chr2:62100932(-) A-I      intronic
chr2:62100933(-) A-I      intronic
chr2:62096949(-) A-I      intronic
chr2:62110393(-) A-I      intronic
chr2:62101102(-) A-I      intronic
chr2:62102273(-) A-I      intronic
chr2:62101107(-) A-I      intronic
chr2:62114185(-) A-I      intronic
chr2:62113447(-) A-I      intronic
chr2:62113419(-) A-I      intronic
chr2:62112819(-) A-I      intronic
chr2:62112694(-) A-I      intronic
chr2:62112638(-) A-I      intronic
chr2:62112622(-) A-I      intronic
chr2:62096939(-) A-I      intronic
chr2:62096963(-) A-I      intronic
chr2:62096973(-) A-I      intronic
chr2:62097017(-) A-I      intronic
chr2:62097039(-) A-I      intronic
chr2:62097040(-) A-I      intronic
chr2:62111531(-) A-I      intronic
chr2:62109247(-) A-I      intronic
chr2:62109206(-) A-I      intronic
chr2:62109205(-) A-I      intronic
chr2:62109134(-) A-I      intronic
chr2:62110456(-) A-I      intronic
chr2:62109116(-) A-I      intronic
chr2:62110333(-) A-I      intronic
chr2:62110447(-) A-I      intronic
chr2:62101660(-) A-I      intronic
chr2:62110354(-) A-I      intronic
chr2:62101108(-) A-I      intronic
chr2:62110352(-) A-I      intronic
chr2:62109708(-) A-I      intronic
chr2:62109703(-) A-I      intronic
chr2:62110314(-) A-I      intronic
chr2:62110302(-) A-I      intronic
chr2:62097156(-) A-I      intronic
chr2:62109919(-) A-I      intronic
chr2:62109918(-) A-I      intronic
chr2:62109847(-) A-I      intronic
chr2:62109657(-) A-I      intronic
chr2:62101694(-) A-I      intronic
chr2:62101623(-) A-I      intronic
chr2:62113311(-) A-I      intronic
chr2:62110374(-) A-I      intronic
chr2:62113465(-) A-I      intronic
chr2:62113411(-) A-I      intronic
chr2:62101124(-) A-I      intronic
chr2:62110521(-) A-I      intronic
chr2:62101054(-) A-I      intronic
chr2:62113363(-) A-I      intronic
chr2:62110500(-) A-I      intronic
chr2:62110444(-) A-I      intronic
chr2:62113380(-) A-I      intronic
chr2:62102275(-) A-I      intronic
chr2:62113966(-) A-I      intronic
chr2:62102217(-) A-I      intronic
chr2:62102274(-) A-I      intronic
chr2:62097245(-) A-I      intronic
chr2:62112842(-) A-I      intronic
chr2:62100960(-) A-I      intronic
chr2:62097925(-) A-I      intronic
chr2:62097023(-) A-I      intronic
chr2:62102092(-) A-I      intronic
chr2:62098043(-) A-I      intronic
chr2:62113286(-) A-I      intronic
chr2:62114062(-) A-I      intronic
chr2:62098369(-) A-I      intronic
chr2:62114023(-) A-I      intronic
chr2:62100769(-) A-I      intronic
chr2:62112820(-) A-I      intronic
chr2:62100797(-) A-I      intronic
chr2:62112775(-) A-I      intronic
chr2:62098399(-) A-I      intronic
chr2:62114166(-) A-I      intronic
chr2:62096933(-) A-I      intronic
chr2:62113374(-) A-I      intronic
chr2:62101664(-) A-I      intronic
chr2:62109685(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CCT4
chr2:62097803(-) A-I intron -    22327324
chr2:62101124(-) A-I intron -    22327324
chr2:62110444(-) A-I intron -    22327324
chr2:62113305(-) T-C intron -    22484847
chr2:62113363(-) A-G intron -    22484847
chr2:62113464(-) A-G intron -    22484847
chr2:62113465(-) A-G intron -    22484847
chr2:62114023(-) A-G intron -    22484847
chr2:62114033(-) A-G intron -    22484847
chr2:62114076(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CCT4
chr2:62095487-62095488(-) m6A 3'UTR       24981863//27773535
chr2:62095580-62095581(-) m6A 3'UTR//exon       27773535
chr2:62095590-62095591(-) m6A 3'UTR//exon       27773535
chr2:62095677-62095678(-) m6A 3'UTR//exon       27773535
chr2:62095770-62095771(-) Am 3'UTR//exon       -
chr2:62099239-62099240(-) m6A CDS//intron       26404942
chr2:62099262-62099263(-) m6A CDS//intron       26404942
chr2:62099270-62099271(-) m6A CDS//intron       26404942
chr2:62103269-62103270(-) m6A CDS//exon       26404942
chr2:62103328-62103329(-) m6A CDS//exon       26404942
chr2:62104059-62104060(-) m6A CDS//exon       26404942
chr2:62104182-62104183(-) m6A CDS       26404942
chr2:62106010-62106011(-) m6A CDS       26404942
chr2:62106041-62106042(-) m6A CDS       26404942
chr2:62106057-62106058(-) m6A CDS       26404942
chr2:62110626-62110627(-) m6A CDS//intron       26404942
chr2:62112175-62112176(-) m6A CDS       26404942
chr2:62112186-62112187(-) m6A CDS       26404942
chr2:62115100-62115101(-) m6A exon//intron       27773535
chr2:62115112-62115113(-) m6A exon//intron       27773535
chr2:62115161-62115162(-) m6A exon//intron       27773535
chr2:62115316-62115317(-) m6A exon//intron       24284625//26404942
chr2:62115565-62115566(-) m6A CDS//exon       24284625//24981863//26404942//27773536//22575960
chr2:62115658-62115659(-) m6A 5'UTR       24284625//24981863//26404942//27773536//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-579-3p
Exosome Lung adenocarcinoma epithelial cell line (A549)     20615901
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Fibroblasts|Mesenchymal stem cells     -
CCT4
Chromatin K562 cells     -
Cytoplasm PTC cell lines (IHH-4|TPC-1)     33898108
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Membrane K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-579-3p
Interactor2: CCT4

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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