Detail Information

Basic Information:


  VIRBase ID:  

HHID00060728

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-579-3p:           NPHP1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-579-3p NPHP1
miRBase
Accession/Entrez ID		 MIMAT0003244 4867
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - JBTS4//NPH1//SLSN1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-579-3p
rs1165224671 chr5:32394404    T/C
rs1190752232 chr5:32394395    C/T
rs1404190650 chr5:32394401    T/C
rs1412824363 chr5:32394357    AAAGACCATAGACTGTAGTAAGTTGATGCAAAAATAATCGCGG/A
rs1415619084 chr5:32394406    C/T
rs376231726 chr5:32394397    C/T
rs768681140 chr5:32394396    G/A
rs939936972 chr5:32394398    G/A
rs1487016067 chr5:32394410    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NPHP1
chr2:110918619(-) A-I      intronic
chr2:110918631(-) A-I      intronic
chr2:110921414(-) A-I      intronic
chr2:110921411(-) A-I      intronic
chr2:110918660(-) A-I      intronic
chr2:110918613(-) A-I      intronic
chr2:110921389(-) A-I      intronic
chr2:110921402(-) A-I      intronic
chr2:110909838(-) A-I      intronic
chr2:110909839(-) A-I      intronic
chr2:110918541(-) A-I      intronic
chr2:110918576(-) A-I      intronic
chr2:110918648(-) A-I      intronic
chr2:110908223(-) A-I      intronic
chr2:110908229(-) A-I      intronic
chr2:110908232(-) A-I      intronic
chr2:110918493(-) A-I      intronic
chr2:110921406(-) A-I      intronic
chr2:110930285(-) A-I      intronic
chr2:110918526(-) A-I      intronic
chr2:110930173(-) A-I      intronic
chr2:110930647(-) A-I      intronic
chr2:110908415(-) A-I      intronic
chr2:110930674(-) A-I      intronic
chr2:110921376(-) A-I      intronic
chr2:110930175(-) A-I      intronic
chr2:110913792(-) A-I      intronic
chr2:110921833(-) A-I      intronic
chr2:110918712(-) A-I      intronic
chr2:110921627(-) A-I      intronic
chr2:110921698(-) A-I      intronic
chr2:110892884(-) A-I      intronic
chr2:110930737(-) A-I      intronic
chr2:110921778(-) A-I      intronic
chr2:110913783(-) A-I      intronic
chr2:110921752(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NPHP1
chr2:110881408-110881409(-) m6A CDS//exon       25456834//24981863//22608085
chr2:110881430-110881431(-) m6A CDS//exon       24209618//25456834//24981863//22608085
chr2:110881476-110881477(-) m6A CDS//exon       25456834//24981863//22608085
chr2:110881485-110881486(-) m6A CDS//exon       25456834//24981863//22608085
chr2:110881525-110881526(-) m6A CDS//exon       24981863//22608085
chr2:110881531-110881532(-) m6A CDS//exon       24981863//22608085
chr2:110922656-110922657(-) m6A CDS//exon       24981863//27773535
chr2:110926039-110926040(-) m6A CDS//exon       24981863
chr2:110927521-110927522(-) m6A CDS//exon       24981863//27773535//22608085
chr2:110935641-110935642(-) m6A 3'UTR//intron       27773535
chr2:110935741-110935742(-) m6A 3'UTR//intron       27773535
chr2:110960031-110960032(-) m6A CDS//intron       24981863
chr2:110960052-110960053(-) m6A CDS//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-579-3p
Exosome Lung adenocarcinoma epithelial cell line (A549)     20615901
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Fibroblasts|Mesenchymal stem cells     -
NPHP1
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-579-3p
Interactor2: NPHP1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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