Detail Information

Basic Information:


  VIRBase ID:  

HHID00060726

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-579-3p:           KIF5B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-579-3p KIF5B
miRBase
Accession/Entrez ID		 MIMAT0003244 3799
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HEL-S-61//KINH//KNS//KNS1//UKHC

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-579-3p
rs1165224671 chr5:32394404    T/C
rs1190752232 chr5:32394395    C/T
rs1404190650 chr5:32394401    T/C
rs1412824363 chr5:32394357    AAAGACCATAGACTGTAGTAAGTTGATGCAAAAATAATCGCGG/A
rs1415619084 chr5:32394406    C/T
rs376231726 chr5:32394397    C/T
rs768681140 chr5:32394396    G/A
rs939936972 chr5:32394398    G/A
rs1487016067 chr5:32394410    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KIF5B
chr10:32305672(-) A-I      intronic
chr10:32301857(-) A-I      intronic
chr10:32301856(-) A-I      intronic
chr10:32301841(-) A-I      intronic
chr10:32305682(-) A-I      intronic
chr10:32305691(-) A-I      intronic
chr10:32305696(-) A-I      intronic
chr10:32305714(-) A-I      intronic
chr10:32305731(-) A-I      intronic
chr10:32305559(-) A-I      intronic
chr10:32310784(-) A-I      intronic
chr10:32303868(-) A-I      intronic
chr10:32301859(-) A-I      intronic
chr10:32301864(-) A-I      intronic
chr10:32301867(-) A-I      intronic
chr10:32301868(-) A-I      intronic
chr10:32301877(-) A-I      intronic
chr10:32301882(-) A-I      intronic
chr10:32304855(-) A-I      intronic
chr10:32304932(-) A-I      intronic
chr10:32304950(-) A-I      intronic
chr10:32304977(-) A-I      intronic
chr10:32305546(-) A-I      intronic
chr10:32305576(-) A-I      intronic
chr10:32305669(-) A-I      intronic
chr10:32301196(-) A-I      intronic
chr10:32302056(-) A-I      intronic
chr10:32305275(-) A-I      intronic
chr10:32301967(-) A-I      intronic
chr10:32304923(-) A-I      intronic
chr10:32304804(-) A-I      intronic
chr10:32301366(-) A-I      intronic
chr10:32304928(-) A-I      intronic
chr10:32313893(-) A-I      intronic
chr10:32304960(-) A-I      intronic
chr10:32305222(-) A-I      intronic
chr10:32305240(-) A-I      intronic
chr10:32301935(-) A-I      intronic
chr10:32305467(-) A-I      intronic
chr10:32305468(-) A-I      intronic
chr10:32301184(-) A-I      intronic
chr10:32301941(-) A-I      intronic
chr10:32303905(-) A-I      intronic
chr10:32301962(-) A-I      intronic
chr10:32301968(-) A-I      intronic
chr10:32305529(-) A-I      intronic
chr10:32305638(-) A-I      intronic
chr10:32303904(-) A-I      intronic
chr10:32304037(-) A-I      intronic
chr10:32305640(-) A-I      intronic
chr10:32304042(-) A-I      intronic
chr10:32305728(-) A-I      intronic
chr10:32330827(-) A-I      intronic
chr10:32302061(-) A-I      intronic
chr10:32305639(-) A-I      intronic
chr10:32304800(-) A-I      intronic
chr10:32301149(-) A-I      intronic
chr10:32301189(-) A-I      intronic
chr10:32313895(-) A-I      intronic
chr10:32329708(-) A-I      intronic
chr10:32305471(-) A-I      intronic
chr10:32301235(-) A-I      intronic
chr10:32301322(-) A-I      intronic
chr10:32304811(-) A-I      intronic
chr10:32329752(-) A-I      intronic
chr10:32330803(-) A-I      intronic
chr10:32302101(-) A-I      intronic
chr10:32304853(-) A-I      intronic
chr10:32301958(-) A-I      intronic
chr10:32303197(-) A-I      intronic
chr10:32329735(-) A-I      intronic
chr10:32303848(-) A-I      intronic
chr10:32332158(-) A-I      intronic
chr10:32304854(-) A-I      intronic
chr10:32301321(-) A-I      intronic
chr10:32330655(-) A-I      intronic
chr10:32304924(-) A-I      intronic
chr10:32317085(-) A-I      intronic
chr10:32313606(-) A-I      intronic
chr10:32313610(-) A-I      intronic
chr10:32305730(-) A-I      intronic
chr10:32330826(-) A-I      intronic
chr10:32301858(-) A-I      intronic
chr10:32301238(-) A-I      intronic
chr10:32305581(-) A-I      intronic
chr10:32305575(-) A-I      intronic
chr10:32305629(-) A-I      intronic
chr10:32305140(-) A-I      intronic
chr10:32315195(-) A-I      intronic
chr10:32305469(-) A-I      intronic
chr10:32305566(-) A-I      intronic
chr10:32304837(-) A-I      intronic
chr10:32302100(-) A-I      intronic
chr10:32305041(-) A-I      intronic
chr10:32305633(-) A-I      intronic
chr10:32301218(-) A-I      intronic
chr10:32302107(-) A-I      intronic
chr10:32302066(-) A-I      intronic
chr10:32305236(-) A-I      intronic
chr10:32301927(-) A-I      intronic
chr10:32305701(-) A-I      intronic
chr10:32305301(-) A-I      intronic
chr10:32315173(-) A-I      intronic
chr10:32305558(-) A-I      intronic
chr10:32335619(-) A-I      intronic
chr10:32303998(-) A-I      intronic
chr10:32330752(-) A-I      intronic
chr10:32317048(-) A-I      intronic
chr10:32313850(-) A-I      intronic
chr10:32301291(-) A-I      intronic
chr10:32304913(-) A-I      intronic
chr10:32301318(-) A-I      intronic
chr10:32302045(-) A-I      intronic
chr10:32305636(-) A-I      intronic
chr10:32301144(-) A-I      intronic
chr10:32305484(-) A-I      intronic
chr10:32340151(-) A-I      intronic
chr10:32301922(-) A-I      intronic
chr10:32332220(-) A-I      intronic
chr10:32304986(-) A-I      intronic
chr10:32304880(-) A-I      intronic
chr10:32302022(-) A-I      intronic
chr10:32330756(-) A-I      intronic
chr10:32304842(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KIF5B
chr10:32299187-32299188(-) m6A 3'UTR       -
chr10:32300224-32300225(-) m6A 3'UTR       26404942
chr10:32300283-32300284(-) m6A 3'UTR       26404942
chr10:32300413-32300414(-) m6A 3'UTR       26404942
chr10:32304465-32304466(-) m6A CDS       26404942
chr10:32304502-32304503(-) m6A CDS       26404942
chr10:32304582-32304583(-) m6A CDS       26404942//27773535
chr10:32307003-32307004(-) m6A CDS//exon       24981863
chr10:32307265-32307266(-) m6A CDS//intron       24981863//26404942//27773535//27371828//22575960
chr10:32307279-32307280(-) m6A CDS//intron       24981863//26404942//27773535//27371828//22575960
chr10:32307299-32307300(-) m6A CDS//intron       24981863//26404942//27773535//27371828//22575960
chr10:32307306-32307307(-) m6A CDS//intron       24981863//26404942//27773535//27371828//22575960
chr10:32307434-32307435(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr10:32307447-32307448(-) Gm CDS//exon       -
chr10:32307454-32307455(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr10:32307459-32307460(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr10:32307468-32307469(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr10:32308790-32308791(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr10:32308799-32308800(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr10:32308821-32308822(-) Cm CDS//exon       -
chr10:32308841-32308842(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr10:32308881-32308882(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr10:32309969-32309970(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr10:32310011-32310012(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr10:32310022-32310023(-) m6A CDS       24981863//27773535//27371828//22575960
chr10:32310047-32310048(-) m6A CDS       24981863//28052920//27773535//22575960
chr10:32310170-32310171(-) m6A CDS       24981863//28052920//27773535
chr10:32311089-32311090(-) m6A CDS       24981863//27773535
chr10:32311125-32311126(-) m6A CDS       24981863//27773535
chr10:32311137-32311138(-) m6A CDS       24981863//27773535
chr10:32311843-32311844(-) m6A CDS       24981863//27773535//22575960
chr10:32311882-32311883(-) m6A CDS       24981863//27773535
chr10:32311916-32311917(-) m6A CDS       24981863//27773535
chr10:32311951-32311952(-) m6A CDS       24981863//27773535
chr10:32317398-32317399(-) m6A CDS       27773535
chr10:32317463-32317464(-) m6A CDS       27773535
chr10:32320044-32320045(-) m6A CDS       24981863//27773535
chr10:32320049-32320050(-) m6A CDS       24981863//27773535
chr10:32320090-32320091(-) m6A CDS       24981863//27773535//22575960
chr10:32320178-32320179(-) m6A CDS       24981863//27773535//22575960
chr10:32321646-32321647(-) Tm CDS       -
chr10:32321663-32321664(-) m6A CDS       24981863//27773535//22575960
chr10:32322787-32322788(-) m6A CDS       24981863//27773535//22575960
chr10:32322871-32322872(-) m6A CDS       24981863//27773535//22575960
chr10:32322943-32322944(-) m6A CDS       24981863//28052920//27773535
chr10:32323661-32323662(-) m6A CDS       24981863//26404942//27773535
chr10:32323714-32323715(-) m6A CDS       24981863//26404942//27773535
chr10:32323748-32323749(-) m6A CDS       24981863
chr10:32323758-32323759(-) m6A CDS       24981863
chr10:32326295-32326296(-) m6A CDS       22575960
chr10:32326463-32326464(-) m6A CDS       22575960
chr10:32328353-32328354(-) m6A CDS       24981863
chr10:32329325-32329326(-) m6A CDS       24981863
chr10:32344791-32344792(-) m6A CDS       27773536
chr10:32344830-32344831(-) m6A CDS       27773536
chr10:32344853-32344854(-) m6A CDS       27371828//27773536
chr10:32344893-32344894(-) m6A CDS       27371828//27773536
chr10:32344950-32344951(-) m6A 5'UTR       24209618//27371828//27773536//22575960
chr10:32345192-32345193(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960
chr10:32345220-32345221(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960
chr10:32345247-32345248(-) m1A 5'UTR       26863196//26863410

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-579-3p
Exosome Lung adenocarcinoma epithelial cell line (A549)     20615901
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Fibroblasts|Mesenchymal stem cells     -
KIF5B
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleus K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-579-3p
Interactor2: KIF5B

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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