Detail Information

Basic Information:


  VIRBase ID:  

HHID00060698

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-573:           TMEM170B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-573 TMEM170B
miRBase
Accession/Entrez ID		 MIMAT0003238 100113407
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-573
rs1203521332 chr4:24520263    C/T
rs1262008333 chr4:24520263    C/CACA
rs1323507871 chr4:24520254    G/T
rs373452545 chr4:24520267    T/C
rs554771730 chr4:24520260    T/C
rs562847917 chr4:24520264    A/G
rs760302615 chr4:24520257    C/T
rs776058506 chr4:24520265    C/T
rs1371079024 chr4:24520270    C/T
rs1447248378 chr4:24520261    TACACATC/T
rs899607846 chr4:24520271    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMEM170B
chr6:11549623(+) A-I      intronic
chr6:11546053(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMEM170B
chr6:11538598-11538599(+) m6A CDS       24284625
chr6:11575702-11575703(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:11575739-11575740(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:11575829-11575830(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr6:11575896-11575897(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr6:11575922-11575923(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr6:11576019-11576020(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr6:11578673-11578674(+) m6A 3'UTR       24981863//22608085
chr6:11578688-11578689(+) m6A 3'UTR       24981863//22608085
chr6:11578741-11578742(+) m6A 3'UTR       24981863//22608085
chr6:11578760-11578761(+) m6A 3'UTR       22608085
chr6:11578777-11578778(+) m6A 3'UTR       22608085
chr6:11578793-11578794(+) m6A 3'UTR       22608085
chr6:11578801-11578802(+) m6A 3'UTR       22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-573
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
TMEM170B
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-573
Interactor2: TMEM170B

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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