Basic Information:

  VIRBase ID:  

HHID00060690

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-573:  MIMAT0003238          DCBLD2:  NM_080927     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-573	DCBLD2
miRBase Accession/Entrez ID	MIMAT0003238	131566
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CLCP1//ESDN

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-573	rs1203521332 chr4:24520263    C/T rs1262008333 chr4:24520263    C/CACA rs1323507871 chr4:24520254    G/T rs373452545 chr4:24520267    T/C rs554771730 chr4:24520260    T/C rs562847917 chr4:24520264    A/G rs760302615 chr4:24520257    C/T rs776058506 chr4:24520265    C/T rs1371079024 chr4:24520270    C/T rs1447248378 chr4:24520261    TACACATC/T rs899607846 chr4:24520271    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DCBLD2	chr3:98563278(-) A-I      intronic chr3:98563502(-) A-I      intronic chr3:98563488(-) A-I      intronic chr3:98563456(-) A-I      intronic chr3:98563439(-) A-I      intronic chr3:98563434(-) A-I      intronic chr3:98563330(-) A-I      intronic chr3:98564832(-) A-I      intronic chr3:98583687(-) A-I      intronic chr3:98563270(-) A-I      intronic chr3:98560873(-) A-I      intronic chr3:98541809(-) A-I      intronic chr3:98550032(-) A-I      intronic chr3:98554395(-) A-I      intronic chr3:98567891(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DCBLD2	chr3:98515206-98515207(-) m6A 3'UTR       26404942 chr3:98515221-98515222(-) m6A 3'UTR       26404942 chr3:98515263-98515264(-) m6A 3'UTR       26404942 chr3:98515316-98515317(-) m6A 3'UTR       26404942 chr3:98515619-98515620(-) m6A 3'UTR       26404942 chr3:98515688-98515689(-) m6A 3'UTR       26404942 chr3:98515755-98515756(-) m6A 3'UTR       26404942 chr3:98515841-98515842(-) m6A 3'UTR       26404942 chr3:98515996-98515997(-) m6A 3'UTR       26404942 chr3:98516045-98516046(-) m6A 3'UTR       26404942 chr3:98516078-98516079(-) m6A 3'UTR       26404942 chr3:98516327-98516328(-) m6A 3'UTR       26404942 chr3:98516393-98516394(-) m6A 3'UTR       26404942 chr3:98516405-98516406(-) m6A 3'UTR       26404942 chr3:98516418-98516419(-) m6A 3'UTR       26404942 chr3:98516425-98516426(-) m6A 3'UTR       26404942 chr3:98516820-98516821(-) m6A 3'UTR       26404942 chr3:98516841-98516842(-) m6A 3'UTR       26404942 chr3:98516889-98516890(-) m6A 3'UTR       26404942 chr3:98517098-98517099(-) m6A 3'UTR       26404942 chr3:98517178-98517179(-) m6A 3'UTR       26404942 chr3:98517295-98517296(-) m6A 3'UTR       26404942 chr3:98517881-98517882(-) m6A 3'UTR       24284625//24981863//26404942//22608085 chr3:98517978-98517979(-) m6A 3'UTR       26404942//27773535 chr3:98518073-98518074(-) m6A 3'UTR       26404942//27773535 chr3:98518379-98518380(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:98518403-98518404(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:98518426-98518427(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:98518492-98518493(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:98518539-98518540(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr3:98518591-98518592(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr3:98518623-98518624(-) m6A CDS       24209618//24981863//26404942//27773535//22608085 chr3:98519503-98519504(-) m6A CDS//exon       26404942 chr3:98519514-98519515(-) m6A CDS//exon       26404942 chr3:98520451-98520452(-) m6A CDS//exon       27773535 chr3:98520482-98520483(-) m6A CDS//exon       27773535 chr3:98520598-98520599(-) m6A exon//intron       27773535 chr3:98520606-98520607(-) m6A exon//intron       27773535 chr3:98520615-98520616(-) m6A exon//intron       27773535 chr3:98520649-98520650(-) m6A exon//intron       27773535 chr3:98520654-98520655(-) m6A exon//intron       27773535 chr3:98520661-98520662(-) m6A exon//intron       27773535 chr3:98520673-98520674(-) m6A exon//intron       27773535 chr3:98520690-98520691(-) m6A exon//intron       27773535 chr3:98530095-98530096(-) m6A CDS//exon       24284625//24981863//26404942//27773535 chr3:98530100-98530101(-) m6A CDS//exon       24284625//24981863//26404942//27773535 chr3:98530340-98530341(-) m6A CDS//exon       24284625//24981863//26404942//27773535 chr3:98530358-98530359(-) m6A CDS//exon       24284625//24981863//26404942//27773535 chr3:98530384-98530385(-) m6A CDS//exon       24284625//24981863//26404942//27773535 chr3:98531312-98531313(-) m6A CDS//exon       26404942 chr3:98531399-98531400(-) m6A exon//intron       24981863 chr3:98531405-98531406(-) m6A exon//intron       24981863 chr3:98536647-98536648(-) m6A CDS//exon       24981863//26404942 chr3:98538121-98538122(-) m6A CDS//exon       24981863//26404942 chr3:98538127-98538128(-) m6A CDS//exon       24981863//26404942 chr3:98538151-98538152(-) m6A CDS//exon       24981863//26404942 chr3:98538161-98538162(-) m6A CDS//exon       24981863//26404942 chr3:98538183-98538184(-) m6A CDS//exon       26404942 chr3:98538249-98538250(-) m6A CDS       26404942 chr3:98539097-98539098(-) m6A CDS       26404942 chr3:98539128-98539129(-) m6A CDS       26404942 chr3:98568411-98568412(-) m6A CDS//exon       26404942 chr3:98600392-98600393(-) m6A CDS//exon//intron       26404942 chr3:98600542-98600543(-) m6A 5'UTR//CDS//exon//intron       26404942 chr3:98600553-98600554(-) m6A 5'UTR//CDS//exon//intron       26404942 chr3:98600569-98600570(-) m6A 5'UTR//CDS//exon//intron       26404942 chr3:98600597-98600598(-) m6A 5'UTR//CDS//exon//intron       26404942//27773535 chr3:98609242-98609243(-) m6A 5'UTR//intron       26404942//27773535 chr3:98614089-98614090(-) m6A exon//intron       27773535 chr3:98620185-98620186(-) m6A 5'UTR       24209618//27773536 chr3:98620417-98620418(-) m6A 5'UTR       24981863//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-573	Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	DCBLD2	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-573
Interactor2: DCBLD2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.