Detail Information

Basic Information:


  VIRBase ID:  

HHID00060534

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-92b-3p:           PIK3AP1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-92b-3p PIK3AP1
miRBase
Accession/Entrez ID		 MIMAT0003218 118788
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BCAP

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-92b-3p
rs1235528450 chr1:155195237    T/C
rs12759620 chr1:155195253    G/C
rs1350664926 chr1:155195246    C/T
rs1355214420 chr1:155195256    T/TCCGGCCCCC

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PIK3AP1
chr10:98467323(-) A-I      intronic
chr10:98450224(-) A-I      intronic
chr10:98467758(-) A-I      intronic
chr10:98469286(-) A-I      intronic
chr10:98469195(-) A-I      intronic
chr10:98462801(-) A-I      intronic
chr10:98364781(-) A-I      intronic
chr10:98412912(-) A-I      intronic
chr10:98439202(-) A-I      intronic
chr10:98439203(-) A-I      intronic
chr10:98452222(-) A-I      intronic
chr10:98431694(-) A-I      intronic
chr10:98413383(-) A-I      intronic
chr10:98361737(-) A-I      intronic
chr10:98452223(-) A-I      intronic
chr10:98452231(-) A-I      intronic
chr10:98452268(-) A-I      intronic
chr10:98431687(-) A-I      intronic
chr10:98454512(-) A-I      intronic
chr10:98364790(-) A-I      intronic
chr10:98465789(-) A-I      intronic
chr10:98412218(-) A-I      intronic
chr10:98364799(-) A-I      intronic
chr10:98388826(-) A-I      intronic
chr10:98420914(-) A-I      intronic
chr10:98400491(-) A-I      intronic
chr10:98365598(-) A-I      intronic
chr10:98420773(-) A-I      intronic
chr10:98437946(-) A-I      intronic
chr10:98413040(-) A-I      intronic
chr10:98462807(-) A-I      intronic
chr10:98464429(-) A-I      intronic
chr10:98465680(-) A-I      intronic
chr10:98412907(-) A-I      intronic
chr10:98413304(-) A-I      intronic
chr10:98365599(-) A-I      intronic
chr10:98415181(-) A-I      intronic
chr10:98457403(-) A-I      intronic
chr10:98464440(-) A-I      intronic
chr10:98415088(-) A-I      intronic
chr10:98462924(-) A-I      intronic
chr10:98412208(-) A-I      intronic
chr10:98395496(-) A-I      intronic
chr10:98462722(-) A-I      intronic
chr10:98438178(-) A-I      intronic
chr10:98365637(-) A-I      intronic
chr10:98400647(-) A-I      intronic
chr10:98364682(-) A-I      intronic
chr10:98415044(-) A-I      intronic
chr10:98450291(-) A-I      intronic
chr10:98450295(-) A-I      intronic
chr10:98437852(-) A-I      intronic
chr10:98467322(-) A-I      intronic
chr10:98400539(-) A-I      intronic
chr10:98388804(-) A-I      intronic
chr10:98400475(-) A-I      intronic
chr10:98365661(-) A-I      intronic
chr10:98468850(-) A-I      intronic
chr10:98454307(-) A-I      intronic
chr10:98400483(-) A-I      intronic
chr10:98464292(-) A-I      intronic
chr10:98415004(-) A-I      intronic
chr10:98462108(-) A-I      intronic
chr10:98468653(-) A-I      intronic
chr10:98413370(-) A-I      intronic
chr10:98468719(-) A-I      intronic
chr10:98462798(-) A-I      intronic
chr10:98438109(-) A-I      intronic
chr10:98467210(-) A-I      intronic
chr10:98412982(-) A-I      intronic
chr10:98413159(-) A-I      intronic
chr10:98412920(-) A-I      intronic
chr10:98412905(-) A-I      intronic
chr10:98464363(-) A-I      intronic
chr10:98468806(-) A-I      intronic
chr10:98467218(-) A-I      intronic
chr10:98390514(-) A-I      intronic
chr10:98413517(-) A-I      intronic
chr10:98400498(-) A-I      intronic
chr10:98462173(-) A-I      intronic
chr10:98413518(-) A-I      intronic
chr10:98467116(-) A-I      intronic
chr10:98431713(-) A-I      intronic
chr10:98431700(-) A-I      intronic
chr10:98473686(-) A-I      intronic
chr10:98468842(-) A-I      intronic
chr10:98412190(-) A-I      intronic
chr10:98468766(-) A-I      intronic
chr10:98468220(-) A-I      intronic
chr10:98468197(-) A-I      intronic
chr10:98467152(-) A-I      intronic
chr10:98413105(-) A-I      intronic
chr10:98361752(-) A-I      intronic
chr10:98365675(-) A-I      intronic
chr10:98413080(-) A-I      intronic
chr10:98465855(-) A-I      intronic
chr10:98461995(-) A-I      intronic
chr10:98413038(-) A-I      intronic
chr10:98439209(-) A-I      intronic
chr10:98464309(-) A-I      intronic
chr10:98465831(-) A-I      intronic
chr10:98365741(-) A-I      intronic
chr10:98384363(-) A-I      intronic
chr10:98361891(-) A-I      intronic
chr10:98465830(-) A-I      intronic
chr10:98361912(-) A-I      intronic
chr10:98462128(-) A-I      intronic
chr10:98462144(-) A-I      intronic
chr10:98438080(-) A-I      intronic
chr10:98462757(-) A-I      intronic
chr10:98361913(-) A-I      intronic
chr10:98395479(-) A-I      intronic
chr10:98364647(-) A-I      intronic
chr10:98395493(-) A-I      intronic
chr10:98364777(-) A-I      intronic
chr10:98465825(-) A-I      intronic
chr10:98412996(-) A-I      intronic
chr10:98397181(-) A-I      intronic
chr10:98468716(-) A-I      intronic
chr10:98389424(-) A-I      intronic
chr10:98465845(-) A-I      intronic
chr10:98467220(-) A-I      intronic
chr10:98413342(-) A-I      intronic
chr10:98415178(-) A-I      intronic
chr10:98467178(-) A-I      intronic
chr10:98468662(-) A-I      intronic
chr10:98412959(-) A-I      intronic
chr10:98385784(-) A-I      intronic
chr10:98465508(-) A-I      intronic
chr10:98462001(-) A-I      intronic
chr10:98413412(-) A-I      intronic
chr10:98465513(-) A-I      intronic
chr10:98413049(-) A-I      intronic
chr10:98468867(-) A-I      intronic
chr10:98361765(-) A-I      intronic
chr10:98384339(-) A-I      intronic
chr10:98389543(-) A-I      intronic
chr10:98462811(-) A-I      intronic
chr10:98468705(-) A-I      intronic
chr10:98454300(-) A-I      intronic
chr10:98464353(-) A-I      intronic
chr10:98413413(-) A-I      intronic
chr10:98462230(-) A-I      intronic
chr10:98457283(-) A-I      intronic
chr10:98360996(-) A-I      intronic
chr10:98412979(-) A-I      intronic
chr10:98467245(-) A-I      intronic
chr10:98464312(-) A-I      intronic
chr10:98462174(-) A-I      intronic
chr10:98465628(-) A-I      intronic
chr10:98373029(-) A-I      intronic
chr10:98364755(-) A-I      intronic
chr10:98462134(-) A-I      intronic
chr10:98465536(-) A-I      intronic
chr10:98438170(-) A-I      intronic
chr10:98361726(-) A-I      intronic
chr10:98467329(-) A-I      intronic
chr10:98413418(-) A-I      intronic
chr10:98457300(-) A-I      intronic
chr10:98415026(-) A-I      intronic
chr10:98462731(-) A-I      intronic
chr10:98437885(-) A-I      intronic
chr10:98450304(-) A-I      intronic
chr10:98462090(-) A-I      intronic
chr10:98468722(-) A-I      intronic
chr10:98454406(-) A-I      intronic
chr10:98450220(-) A-I      intronic
chr10:98464367(-) A-I      intronic
chr10:98464230(-) A-I      intronic
chr10:98467187(-) A-I      intronic
chr10:98464240(-) A-I      intronic
chr10:98364013(-) A-I      intronic
chr10:98464442(-) A-I      intronic
chr10:98464388(-) A-I      intronic
chr10:98413373(-) A-I      intronic
chr10:98365719(-) A-I      intronic
chr10:98365629(-) A-I      intronic
chr10:98467203(-) A-I      intronic
chr10:98365791(-) A-I      intronic
chr10:98464470(-) A-I      intronic
chr10:98454451(-) A-I      intronic
chr10:98467188(-) A-I      intronic
chr10:98468807(-) A-I      intronic
chr10:98365717(-) A-I      intronic
chr10:98465442(-) A-I      intronic
chr10:98467223(-) A-I      intronic
chr10:98384413(-) A-I      intronic
chr10:98467115(-) A-I      intronic
chr10:98361868(-) A-I      intronic
chr10:98464218(-) A-I      intronic
chr10:98462088(-) A-I      intronic
chr10:98415142(-) A-I      intronic
chr10:98415043(-) A-I      intronic
chr10:98438110(-) A-I      intronic
chr10:98361835(-) A-I      intronic
chr10:98468837(-) A-I      intronic
chr10:98431673(-) A-I      intronic
chr10:98423117(-) A-I      intronic
chr10:98462248(-) A-I      intronic
chr10:98413050(-) A-I      intronic
chr10:98365693(-) A-I      intronic
chr10:98468768(-) A-I      intronic
chr10:98457410(-) A-I      intronic
chr10:98365729(-) A-I      intronic
chr10:98462247(-) A-I      intronic
chr10:98431790(-) A-I      intronic
chr10:98437859(-) A-I      intronic
chr10:98457455(-) A-I      intronic
chr10:98454492(-) A-I      intronic
chr10:98365732(-) A-I      intronic
chr10:98413079(-) A-I      intronic
chr10:98365826(-) A-I      intronic
chr10:98450240(-) A-I      intronic
chr10:98439160(-) A-I      intronic
chr10:98364894(-) A-I      intronic
chr10:98413382(-) A-I      intronic
chr10:98462854(-) A-I      intronic
chr10:98415182(-) A-I      intronic
chr10:98364901(-) A-I      intronic
chr10:98467147(-) A-I      intronic
chr10:98464389(-) A-I      intronic
chr10:98413449(-) A-I      intronic
chr10:98360986(-) A-I      intronic
chr10:98454414(-) A-I      intronic
chr10:98361805(-) A-I      intronic
chr10:98469301(-) A-I      intronic
chr10:98467723(-) A-I      intronic
chr10:98469253(-) A-I      intronic
chr10:98467631(-) A-I      intronic
chr10:98467595(-) A-I      intronic
chr10:98465412(-) A-I      intronic
chr10:98415058(-) A-I      intronic
chr10:98468778(-) A-I      intronic
chr10:98462947(-) A-I      intronic
chr10:98457713(-) A-I      intronic
chr10:98469230(-) A-I      intronic
chr10:98365608(-) A-I      intronic
chr10:98449325(-) A-I      intronic
chr10:98467763(-) A-I      intronic
chr10:98361821(-) A-I      intronic
chr10:98412970(-) A-I      intronic
chr10:98469297(-) A-I      intronic
chr10:98469298(-) A-I      intronic
chr10:98469207(-) A-I      intronic
chr10:98469222(-) A-I      intronic
chr10:98469203(-) A-I      intronic
chr10:98469227(-) A-I      intronic
chr10:98467727(-) A-I      intronic
chr10:98462741(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PIK3AP1
chr10:98467727(-) A-I intron -    22327324
chr10:98360996(-) A-G intron -    22484847
chr10:98365791(-) A-G intron -    22484847
chr10:98365826(-) A-G intron -    22484847
chr10:98402062(-) T-C intron -    22484847
chr10:98402089(-) T-C intron -    22484847
chr10:98412907(-) A-G intron -    22484847
chr10:98412912(-) A-G intron -    22484847
chr10:98462798(-) A-G intron -    22484847
chr10:98462924(-) A-G intron -    22484847
chr10:98464292(-) A-G intron -    22484847
chr10:98464309(-) A-G intron -    22484847
chr10:98464353(-) A-G intron -    22484847
chr10:98464363(-) A-G intron -    22484847
chr10:98467115(-) A-G intron -    22484847
chr10:98467116(-) A-G intron -    22484847
chr10:98467147(-) A-G intron -    22484847
chr10:98467178(-) A-G intron -    22484847
chr10:98467210(-) A-G intron -    22484847
chr10:98467723(-) A-G intron -    22484847
chr10:98467763(-) A-G intron -    22484847
chr10:98469207(-) A-G intron -    22484847
chr10:98469222(-) A-G intron -    22484847
chr10:98469297(-) A-G intron -    22484847
chr10:98469298(-) A-G intron -    22484847
chr10:98469301(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PIK3AP1
chr10:98355076-98355077(-) m6A 3'UTR       24981863//27773535
chr10:98355106-98355107(-) m6A 3'UTR       24981863//28052920//27773535
chr10:98355142-98355143(-) m6A 3'UTR       24981863//28052920//27773535
chr10:98355294-98355295(-) m6A 3'UTR       24209618//24981863//28052920//27773535//27371828//22608085
chr10:98355302-98355303(-) m6A 3'UTR       24209618//24981863//28052920//27773535//27371828//22608085
chr10:98355318-98355319(-) m6A 3'UTR       24209618//24981863//28052920//27773535//27371828//22608085
chr10:98355374-98355375(-) m6A CDS//exon       24209618//24981863//27773535//27371828
chr10:98362071-98362072(-) m6A CDS//exon       24209618//27773535//27371828
chr10:98362094-98362095(-) m6A CDS//exon       24209618//27773535
chr10:98363516-98363517(-) m6A exon//intron       27773535
chr10:98363530-98363531(-) m6A exon//intron       27773535
chr10:98363584-98363585(-) m6A exon//intron       27773535
chr10:98369492-98369493(-) m6A CDS//exon       24981863//27773535//27371828
chr10:98369500-98369501(-) m6A CDS//exon       24981863//27773535//27371828
chr10:98376398-98376399(-) m6A CDS//exon       27773535//27371828
chr10:98376429-98376430(-) m6A CDS//exon       27773535//27371828
chr10:98376445-98376446(-) m6A CDS//exon       27773535//27371828
chr10:98378442-98378443(-) m6A exon//intron       27773535
chr10:98405380-98405381(-) m6A CDS//exon       27773535
chr10:98405408-98405409(-) m6A CDS//exon       27773535
chr10:98408443-98408444(-) m6A CDS//exon       27773535
chr10:98408457-98408458(-) m6A CDS//exon       27773535
chr10:98469583-98469584(-) m6A CDS       27371828
chr10:98469668-98469669(-) m6A CDS       27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-92b-3p
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Peripheral blood     31746410
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome Cerebrospinal fluid     25420022
Exosome Blood|B lymphoblastoid cells|Breast tissue|Endothelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Tongue tissue     -
Extracellular vesicle HEK-293T cells     22849433
Microvesicle Seminal plasma     23539611
Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
PIK3AP1
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-92b-3p
Iodine Green 9956454 Drug sensitive
Sensorad 99342 Drug sensitive
8-Aminoadenosine 96851 Drug resistant
Gardenin B 96539 Drug sensitive
Hydrazinecarboximidamide, 2,2'-(carbonylbis(imino-3,1-phenyleneethylidyne))bis-, hydrochloride 9577144 Drug sensitive
Actinomycin X4357G methoxime 9573583 Drug sensitive
(3Z,8S,11Z,16S)-8,16-Bis(2-oxopropyl)-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetrone 92973777 Drug sensitive
L-2-Aminobutyric acid 80283 Drug sensitive
Vancide 26 79411 Drug sensitive
Cinerubin B 73593 Drug sensitive
4-(2-Naphthylamino)phenol 7141 Drug sensitive
Sulbentine 67686 Drug sensitive
Ixabepilone 6445540 Drug sensitive
Piriqualone 6015423 Drug sensitive
trans-1,2-Bis(propylsulfonyl)ethylene 5904452 Drug sensitive
1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive
Artelasticin 5471311 Drug sensitive
2-(1,3-Benzodioxol-5-yl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one 5466137 Drug sensitive
6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive
Herveline O 5459269 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Thiram 5455 Drug sensitive
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive
Indanthren Corinth RK 5351878 Drug sensitive
5-Phenyl-N-(3,4,5-trimethoxyphenyl)-1,3-oxazol-2-amine 5329854 Drug sensitive
1-[3-(Propylamino)phenyl]-N-(pyridin-4-ylmethylideneamino)pyrazolo[3,4-d]pyrimidin-4-amine 53239979 Drug sensitive
Vorinostat 5311 Drug sensitive
Spiperone 5265 Drug resistant
Kekule 499328 Drug sensitive
10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive
6-Methoxy-7-(2lambda(5)-1,2-triazadienyl)-5,8-quinolinedione 494043 Drug sensitive
Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive
BAS100 Monohydrate 45028404 Drug sensitive
1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive
Isopinnatal 44558939 Drug sensitive
1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive
2,6-Epoxy-2H-1-benzoxocin-5(6H)-one, 6,8-dimethyl- 434882 Drug sensitive
Di-n-octyl-secalonsaure A 430141 Drug sensitive
2-Amino-4-(2-hydroxy-4-methylphenyl)-5-phenylpyrimidine 392744 Drug sensitive
beta-Lapachone 3885 Drug sensitive
Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive
L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive
4-Phenacyloxychromen-2-one 386272 Drug resistant
2-Ethylaminoestradiol 384235 Drug sensitive
(-)7,8-Dihydrocalanolide A 383107 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
4-Methylthio-N-(3,4,5-trimethoxybenzyl)aniline 373808 Drug sensitive
Sanguilutine pseudobase 371258 Drug sensitive
1-(4-Methoxy-2-methylphenyl)naphtho[1,2-c]furan-3(1H)-one 369148 Drug sensitive
1-Chloro-3-(3-chloropropylsulfonylsulfanyl)propane 355643 Drug sensitive
Maxima isoflavone D 343081 Drug sensitive
Bis(helenalinyl)glutarate 336831 Drug sensitive
Rustaiyan A 324967 Drug sensitive
(15S)-15-Ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one 2724040 Drug sensitive
Antineoplastic-92915 261051 Drug sensitive
5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive
(2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive
Prumycin HCl 24197905 Drug resistant
9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive
4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive
3-Amino-N-(2-fluorophenyl)-5-oxo-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide 1856915 Drug sensitive
Sudan II 18386 Drug sensitive
(2R)-2-[(3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(5S)-5-[(3S)-5-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2-yl]propanoic acid 152743331 Drug sensitive
Arsenic trioxide 14888 Drug sensitive
Astrazon Orange R 135747272 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
(2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive
Melampodinin 11953936 Drug sensitive
2,2'-Bioxirane 11254 Drug sensitive
Perillyl alcohol 10819 Drug sensitive
Cladospirone bisepoxide 10316810 Drug sensitive
Chimaphilin 101211 Drug sensitive
6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant
1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant
tgf.alpha.-pe40 - Drug resistant
tp4ek - Drug resistant
tunicamycin - Drug resistant
(z) 3,3',4,5-tetramethoxystilbene - Drug sensitive
(z) 4-acetoxy-(3,4',5)-trimethoxystilbene - Drug sensitive
(Z)-N-phenyl-3-(3,4,5-trimethoxystyryl)pyridin-2-amine - Drug sensitive
1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive
2-(4-(methylsulfonyl)phenyl)-6-p-tolyl-4,5-dihydropyridazin-3(2H)-one - Drug sensitive
2,4-diethoxyestra-1,3,5(10)trien-3,17.beta.-diol - Drug sensitive
2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive
4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive
4-morpholinecarbodithioic acid, antimony complex - Drug sensitive
4-thiomorpholinecarbodithioic acid, antimony complex - Drug sensitive
5-[2-(4-methoxyphenyl)ethyl]-1,2,3-dimethoxy benzene - Drug sensitive
7-n,n-dimethylamino brefeldin a hydrochloride - Drug sensitive
9-acridinamine, n-(4-ethoxyphenyl)-, monohydrochloride - Drug sensitive
anthracen-9-one, 10-[(2-methoxyphenyl)methylene]- - Drug sensitive
benzamide, 5-bromo-2-hydroxy-n-[3-(trifluoromethyl)phenyl]- - Drug sensitive
benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive
E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive
inosine, 6-thio-, 2',3',5'-tris(4-methoxybenzoate) - Drug sensitive
isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive
phosphonium, (3-bromopropyl)triphenyl- bromide - Drug sensitive
(Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
(Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive
2-amino-5-chloro-6-(2-thiazolyloxy)-benzimidazole - Drug sensitive
4-carbo-1-thiazolidine-3-o-gluconyl-.gamma.-lactone - Drug sensitive
9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive
antineoplastic-615538 - Drug sensitive
antineoplastic-d665837 - Drug sensitive
arylmethylene-f - Drug sensitive
carzinostatin - Drug sensitive
cyclo [n-naphthoyl-d-lys-asn-gln-trp-ala-val-d-ala-his-leu] - Drug sensitive
geldanamycin-11-hexadecanic acid ester - Drug sensitive
his 47-methyl ct - Drug sensitive
n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-92b-3p
(S)-N-[1-(3-Morpholin-4-yl-phenyl)-ethyl]-3-phenyl-acrylamide 9949648 Drug interaction    RC00005944
Gemcitabine 60750 Drug interaction    RC00005940
Vincristine 5978 Drug interaction    RC00005938
Eloxatine 5310940 Drug interaction    RC00005943
Diethylstilbestrol 448537 Drug interaction    RC00005942
Bortezomib 387447 Drug interaction    RC00005941
5-Fluorouracil 3385 Drug interaction    RC00005937
Doxorubicin 31703 Drug interaction    RC00005939
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005936
Trastuzumab - Drug interaction    RC00005945
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-92b-3p
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-92b-3p
Interactor2: PIK3AP1

Evidence Support:


Weak-Evidence HITS-CLIP
Support Database ViRBase

References:


PMID 22473208 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line Jijoye cells Interactor2 expression None
Description Our HITS-CLIP data yield 1185 human 3'UTRs targeted by members of the miR-17~92 cluster in Jijoye cells. Comparison to the 1664 3'UTRs targeted by EBV miRNAs reveals 740 shared genes (44% of EBV targets and 62% of miR-17~92 targets; Figure 6B and Supplementary Table 7). Thus, EBV miRNAs co-target a majority of miR-17~92 regulated mRNAs, which are assigned to a variety of pathways, most notably regulating transcription, apoptosis, and the cell cycle (Figure 6C). Similarly, other abundant immunologically relevant miRNAs, 142-3p and miR-155, co-target with EBV miRNAs a large fraction of their Ago-bound 3'UTRs, representing ~60% of the targets for each of these host miRNAs (Supplementary Figure 5).

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