Basic Information:

  VIRBase ID:  

HHID00060412

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-92b-3p:  MIMAT0003218          DSTYK:  NM_015375     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-92b-3p	DSTYK
miRBase Accession/Entrez ID	MIMAT0003218	25778
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CAKUT1//DustyPK//HDCMD38P//RIP5//RIPK5//SPG23

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-92b-3p	rs1235528450 chr1:155195237    T/C rs12759620 chr1:155195253    G/C rs1350664926 chr1:155195246    C/T rs1355214420 chr1:155195256    T/TCCGGCCCCC

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DSTYK	chr1:205142952(-) A-I      intronic chr1:205142949(-) A-I      intronic chr1:205142975(-) A-I      intronic chr1:205142985(-) A-I      intronic chr1:205142958(-) A-I      intronic chr1:205142967(-) A-I      intronic chr1:205172962(-) A-I      intronic chr1:205172961(-) A-I      intronic chr1:205171008(-) A-I      intronic chr1:205170240(-) A-I      intronic chr1:205170227(-) A-I      intronic chr1:205170226(-) A-I      intronic chr1:205170221(-) A-I      intronic chr1:205169591(-) A-I      intronic chr1:205169551(-) A-I      intronic chr1:205169313(-) A-I      intronic chr1:205166043(-) A-I      intronic chr1:205166025(-) A-I      intronic chr1:205166024(-) A-I      intronic chr1:205165563(-) A-I      intronic chr1:205165519(-) A-I      intronic chr1:205165511(-) A-I      intronic chr1:205154614(-) A-I      intronic chr1:205154325(-) A-I      intronic chr1:205154220(-) A-I      intronic chr1:205154217(-) A-I      intronic chr1:205154091(-) A-I      intronic chr1:205153780(-) A-I      intronic chr1:205150974(-) A-I      intronic chr1:205149665(-) A-I      intronic chr1:205143012(-) A-I      intronic chr1:205142971(-) A-I      intronic chr1:205142436(-) A-I      intronic chr1:205142435(-) A-I      intronic chr1:205133504(-) A-I      intronic chr1:205128292(-) A-I      intronic chr1:205145860(-) A-I      intronic chr1:205177745(-) A-I      intronic chr1:205177143(-) A-I      intronic chr1:205177006(-) A-I      intronic chr1:205177071(-) A-I      intronic chr1:205134264(-) A-I      intronic chr1:205143759(-) A-I      intronic chr1:205150659(-) A-I      intronic chr1:205150661(-) A-I      intronic chr1:205146168(-) A-I      intronic chr1:205126720(-) A-I      intronic chr1:205148003(-) A-I      intronic chr1:205172502(-) A-I      intronic chr1:205141357(-) A-I      intronic chr1:205146104(-) A-I      intronic chr1:205148188(-) A-I      intronic chr1:205154567(-) A-I      intronic chr1:205165635(-) A-I      intronic chr1:205172515(-) A-I      intronic chr1:205171065(-) A-I      intronic chr1:205144416(-) A-I      intronic chr1:205150942(-) A-I      intronic chr1:205149820(-) A-I      intronic chr1:205114651(-) A-I      3'UTR chr1:205171105(-) A-I      intronic chr1:205148181(-) A-I      intronic chr1:205168045(-) A-I      intronic chr1:205165983(-) A-I      intronic chr1:205146142(-) A-I      intronic chr1:205164099(-) A-I      intronic chr1:205124283(-) A-I      intronic chr1:205135064(-) A-I      intronic chr1:205169452(-) A-I      intronic chr1:205143289(-) A-I      intronic chr1:205146332(-) A-I      intronic chr1:205143123(-) A-I      intronic chr1:205171016(-) A-I      intronic chr1:205153617(-) A-I      intronic chr1:205132636(-) A-I      intronic chr1:205124259(-) A-I      intronic chr1:205150934(-) A-I      intronic chr1:205171075(-) A-I      intronic chr1:205135546(-) A-I      intronic chr1:205128285(-) A-I      intronic chr1:205141685(-) A-I      intronic chr1:205169303(-) A-I      intronic chr1:205177767(-) A-I      intronic chr1:205169521(-) A-I      intronic chr1:205134961(-) A-I      intronic chr1:205150665(-) A-I      intronic chr1:205143962(-) A-I      intronic chr1:205177835(-) A-I      intronic chr1:205164029(-) A-I      intronic chr1:205166002(-) A-I      intronic chr1:205171111(-) A-I      intronic chr1:205161968(-) A-I      intronic chr1:205161943(-) A-I      intronic chr1:205134289(-) A-I      intronic chr1:205141136(-) A-I      intronic chr1:205148006(-) A-I      intronic chr1:205150679(-) A-I      intronic chr1:205142439(-) A-I      intronic chr1:205134324(-) A-I      intronic chr1:205146213(-) A-I      intronic chr1:205170976(-) A-I      intronic chr1:205148555(-) A-I      intronic chr1:205169574(-) A-I      intronic chr1:205161951(-) A-I      intronic chr1:205153588(-) A-I      intronic chr1:205112269(-) A-I      3'UTR chr1:205133487(-) A-I      intronic chr1:205143067(-) A-I      intronic chr1:205177847(-) A-I      intronic chr1:205169302(-) A-I      intronic chr1:205144138(-) A-I      intronic chr1:205148559(-) A-I      intronic chr1:205177070(-) A-I      intronic chr1:205135529(-) A-I      intronic chr1:205148189(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DSTYK	chr1:205148555(-) A-I intron -    15545495 chr1:205148559(-) A-I intron -    15545495 chr1:205177799(-) A-I intron -    21960545 chr1:205124232(-) G-C intron -    22484847 chr1:205124259(-) A-G intron -    22484847 chr1:205124274(-) T-C intron -    22484847 chr1:205124283(-) A-G intron -    22484847 chr1:205134264(-) A-G intron -    22484847 chr1:205143067(-) A-G intron -    22484847 chr1:205143123(-) A-G intron -    22484847 chr1:205143289(-) A-G intron -    22484847 chr1:205143759(-) A-G intron -    22484847 chr1:205143867(-) T-A intron -    22484847 chr1:205150659(-) A-G intron -    22484847 chr1:205150661(-) A-G intron -    22484847 chr1:205150665(-) A-G intron -    22484847 chr1:205150679(-) A-G intron -    22484847 chr1:205153617(-) A-G intron -    22484847 chr1:205171016(-) A-G intron -    22484847 chr1:205171065(-) A-G intron -    22484847 chr1:205171075(-) A-G intron -    22484847 chr1:205171105(-) A-G intron -    22484847 chr1:205171111(-) A-G intron -    22484847 chr1:205172914(-) A-C intron -    22484847 chr1:205177835(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DSTYK	chr1:205116080-205116081(-) m6A 3'UTR       27773535 chr1:205116127-205116128(-) m6A 3'UTR       27773535 chr1:205116215-205116216(-) m6A 3'UTR       27773535 chr1:205116221-205116222(-) m6A 3'UTR       27773535 chr1:205116229-205116230(-) m6A 3'UTR       27773535 chr1:205116266-205116267(-) m6A 3'UTR       27773535 chr1:205116341-205116342(-) m6A 3'UTR       27773535 chr1:205116353-205116354(-) m6A 3'UTR       27773535 chr1:205116526-205116527(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205116553-205116554(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205116560-205116561(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205116578-205116579(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205116594-205116595(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205116676-205116677(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr1:205116703-205116704(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr1:205116710-205116711(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr1:205132927-205132928(-) m6A CDS//intron       24284625 chr1:205138324-205138325(-) m6A CDS//intron       27773535//22608085 chr1:205138347-205138348(-) m6A CDS//intron       24284625//24981863//27773535//22575960//22608085 chr1:205138466-205138467(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:205138526-205138527(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205138557-205138558(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205138591-205138592(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205138609-205138610(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205138658-205138659(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205138745-205138746(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205138765-205138766(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205138846-205138847(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:205156578-205156579(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085 chr1:205156609-205156610(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr1:205156643-205156644(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205156683-205156684(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205156692-205156693(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205156718-205156719(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205156724-205156725(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:205156873-205156874(-) m6A CDS       24284625//24209618//24981863 chr1:205180413-205180414(-) m6A CDS       24284625//24981863//27773536 chr1:205180521-205180522(-) m6A CDS       24981863//27371828//27773536 chr1:205180532-205180533(-) m6A CDS       24981863//27371828//27773536 chr1:205180680-205180681(-) m6A 5'UTR       25456834//24981863//27371828//27773536//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-92b-3p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Peripheral blood     31746410 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Cerebrospinal fluid     25420022 Exosome Blood|B lymphoblastoid cells|Breast tissue|Endothelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Tongue tissue     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Seminal plasma     23539611 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	DSTYK	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-92b-3p	Iodine Green 9956454 Drug sensitive Sensorad 99342 Drug sensitive 8-Aminoadenosine 96851 Drug resistant Gardenin B 96539 Drug sensitive Hydrazinecarboximidamide, 2,2'-(carbonylbis(imino-3,1-phenyleneethylidyne))bis-, hydrochloride 9577144 Drug sensitive Actinomycin X4357G methoxime 9573583 Drug sensitive (3Z,8S,11Z,16S)-8,16-Bis(2-oxopropyl)-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetrone 92973777 Drug sensitive L-2-Aminobutyric acid 80283 Drug sensitive Vancide 26 79411 Drug sensitive Cinerubin B 73593 Drug sensitive 4-(2-Naphthylamino)phenol 7141 Drug sensitive Sulbentine 67686 Drug sensitive Ixabepilone 6445540 Drug sensitive Piriqualone 6015423 Drug sensitive trans-1,2-Bis(propylsulfonyl)ethylene 5904452 Drug sensitive 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive Artelasticin 5471311 Drug sensitive 2-(1,3-Benzodioxol-5-yl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one 5466137 Drug sensitive 6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive Herveline O 5459269 Drug sensitive Cuspidatin C 5459164 Drug sensitive Thiram 5455 Drug sensitive (1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive Indanthren Corinth RK 5351878 Drug sensitive 5-Phenyl-N-(3,4,5-trimethoxyphenyl)-1,3-oxazol-2-amine 5329854 Drug sensitive 1-[3-(Propylamino)phenyl]-N-(pyridin-4-ylmethylideneamino)pyrazolo[3,4-d]pyrimidin-4-amine 53239979 Drug sensitive Vorinostat 5311 Drug sensitive Spiperone 5265 Drug resistant Kekule 499328 Drug sensitive 10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive 6-Methoxy-7-(2lambda(5)-1,2-triazadienyl)-5,8-quinolinedione 494043 Drug sensitive Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive BAS100 Monohydrate 45028404 Drug sensitive 1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive Isopinnatal 44558939 Drug sensitive 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive 2,6-Epoxy-2H-1-benzoxocin-5(6H)-one, 6,8-dimethyl- 434882 Drug sensitive Di-n-octyl-secalonsaure A 430141 Drug sensitive 2-Amino-4-(2-hydroxy-4-methylphenyl)-5-phenylpyrimidine 392744 Drug sensitive beta-Lapachone 3885 Drug sensitive Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive 4-Phenacyloxychromen-2-one 386272 Drug resistant 2-Ethylaminoestradiol 384235 Drug sensitive (-)7,8-Dihydrocalanolide A 383107 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant 4-Methylthio-N-(3,4,5-trimethoxybenzyl)aniline 373808 Drug sensitive Sanguilutine pseudobase 371258 Drug sensitive 1-(4-Methoxy-2-methylphenyl)naphtho[1,2-c]furan-3(1H)-one 369148 Drug sensitive 1-Chloro-3-(3-chloropropylsulfonylsulfanyl)propane 355643 Drug sensitive Maxima isoflavone D 343081 Drug sensitive Bis(helenalinyl)glutarate 336831 Drug sensitive Rustaiyan A 324967 Drug sensitive (15S)-15-Ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one 2724040 Drug sensitive Antineoplastic-92915 261051 Drug sensitive 5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive Prumycin HCl 24197905 Drug resistant 9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive 4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive 3-Amino-N-(2-fluorophenyl)-5-oxo-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide 1856915 Drug sensitive Sudan II 18386 Drug sensitive (2R)-2-[(3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(5S)-5-[(3S)-5-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2-yl]propanoic acid 152743331 Drug sensitive Arsenic trioxide 14888 Drug sensitive Astrazon Orange R 135747272 Drug sensitive C8, Carbonyl prodigiosine 135540857 Drug sensitive (2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive Melampodinin 11953936 Drug sensitive 2,2'-Bioxirane 11254 Drug sensitive Perillyl alcohol 10819 Drug sensitive Cladospirone bisepoxide 10316810 Drug sensitive Chimaphilin 101211 Drug sensitive 6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant 1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant tgf.alpha.-pe40 - Drug resistant tp4ek - Drug resistant tunicamycin - Drug resistant (z) 3,3',4,5-tetramethoxystilbene - Drug sensitive (z) 4-acetoxy-(3,4',5)-trimethoxystilbene - Drug sensitive (Z)-N-phenyl-3-(3,4,5-trimethoxystyryl)pyridin-2-amine - Drug sensitive 1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive 2-(4-(methylsulfonyl)phenyl)-6-p-tolyl-4,5-dihydropyridazin-3(2H)-one - Drug sensitive 2,4-diethoxyestra-1,3,5(10)trien-3,17.beta.-diol - Drug sensitive 2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive 4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 4-thiomorpholinecarbodithioic acid, antimony complex - Drug sensitive 5-[2-(4-methoxyphenyl)ethyl]-1,2,3-dimethoxy benzene - Drug sensitive 7-n,n-dimethylamino brefeldin a hydrochloride - Drug sensitive 9-acridinamine, n-(4-ethoxyphenyl)-, monohydrochloride - Drug sensitive anthracen-9-one, 10-[(2-methoxyphenyl)methylene]- - Drug sensitive benzamide, 5-bromo-2-hydroxy-n-[3-(trifluoromethyl)phenyl]- - Drug sensitive benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive inosine, 6-thio-, 2',3',5'-tris(4-methoxybenzoate) - Drug sensitive isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive phosphonium, (3-bromopropyl)triphenyl- bromide - Drug sensitive (Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive 2-amino-5-chloro-6-(2-thiazolyloxy)-benzimidazole - Drug sensitive 4-carbo-1-thiazolidine-3-o-gluconyl-.gamma.-lactone - Drug sensitive 9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive antineoplastic-615538 - Drug sensitive antineoplastic-d665837 - Drug sensitive arylmethylene-f - Drug sensitive carzinostatin - Drug sensitive cyclo [n-naphthoyl-d-lys-asn-gln-trp-ala-val-d-ala-his-leu] - Drug sensitive geldanamycin-11-hexadecanic acid ester - Drug sensitive his 47-methyl ct - Drug sensitive n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-92b-3p	(S)-N-[1-(3-Morpholin-4-yl-phenyl)-ethyl]-3-phenyl-acrylamide 9949648 Drug interaction    RC00005944 Gemcitabine 60750 Drug interaction    RC00005940 Vincristine 5978 Drug interaction    RC00005938 Eloxatine 5310940 Drug interaction    RC00005943 Diethylstilbestrol 448537 Drug interaction    RC00005942 Bortezomib 387447 Drug interaction    RC00005941 5-Fluorouracil 3385 Drug interaction    RC00005937 Doxorubicin 31703 Drug interaction    RC00005939 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005936 Trastuzumab - Drug interaction    RC00005945

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-92b-3p	Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-92b-3p
Interactor2: DSTYK

Evidence Support:

Weak-Evidence	HITS-CLIP
Support Database	ViRBase

References:

PMID	22473208	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Jijoye cells	Interactor2 expression	None
Description	Our HITS-CLIP data yield 1185 human 3'UTRs targeted by members of the miR-17~92 cluster in Jijoye cells. Comparison to the 1664 3'UTRs targeted by EBV miRNAs reveals 740 shared genes (44% of EBV targets and 62% of miR-17~92 targets; Figure 6B and Supplementary Table 7). Thus, EBV miRNAs co-target a majority of miR-17~92 regulated mRNAs, which are assigned to a variety of pathways, most notably regulating transcription, apoptosis, and the cell cycle (Figure 6C). Similarly, other abundant immunologically relevant miRNAs, 142-3p and miR-155, co-target with EBV miRNAs a large fraction of their Ago-bound 3'UTRs, representing ~60% of the targets for each of these host miRNAs (Supplementary Figure 5).