Basic Information:

  VIRBase ID:  

HHID00059958

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-505-3p:  MIMAT0002876          USP10:  NR_073578     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-505-3p	USP10
miRBase Accession/Entrez ID	MIMAT0002876	9100
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	UBPO

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-505-3p	rs1399022406 chrX:139924172    A/C rs752398973 chrX:139924166    C/T rs769780782 chrX:139924181    G/A rs1164352633 chrX:139924164    AACCAGCAAGTGTTG/A rs143213653 chrX:139924180    C/T rs751353935 chrX:139924177    T/C rs762594106 chrX:139924174    T/A rs763934588 chrX:139924176    T/C rs763934588 chrX:139924176    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	USP10	chr16:84783813(+) A-I      intronic chr16:84783858(+) A-I      intronic chr16:84783849(+) A-I      intronic chr16:84759718(+) A-I      intronic chr16:84807698(+) A-I      intronic chr16:84807700(+) A-I      intronic chr16:84807709(+) A-I      intronic chr16:84807819(+) A-I      intronic chr16:84807870(+) A-I      intronic chr16:84808177(+) A-I      intronic chr16:84741506(+) A-I      intronic chr16:84783828(+) A-I      intronic chr16:84807829(+) A-I      intronic chr16:84748723(+) A-I      intronic chr16:84807831(+) A-I      intronic chr16:84807836(+) A-I      intronic chr16:84783799(+) A-I      intronic chr16:84807685(+) A-I      intronic chr16:84805779(+) A-I      intronic chr16:84738912(+) A-I      intronic chr16:84736437(+) A-I      intronic chr16:84735883(+) A-I      intronic chr16:84735780(+) A-I      intronic chr16:84735763(+) A-I      intronic chr16:84741604(+) A-I      intronic chr16:84741499(+) A-I      intronic chr16:84810609(+) A-I      intronic chr16:84810568(+) A-I      intronic chr16:84810536(+) A-I      intronic chr16:84810523(+) A-I      intronic chr16:84808280(+) A-I      intronic chr16:84807785(+) A-I      intronic chr16:84807777(+) A-I      intronic chr16:84807767(+) A-I      intronic chr16:84807660(+) A-I      intronic chr16:84807601(+) A-I      intronic chr16:84807600(+) A-I      intronic chr16:84805878(+) A-I      intronic chr16:84805877(+) A-I      intronic chr16:84789167(+) A-I      intronic chr16:84805824(+) A-I      intronic chr16:84805787(+) A-I      intronic chr16:84805324(+) A-I      intronic chr16:84805317(+) A-I      intronic chr16:84805298(+) A-I      intronic chr16:84805279(+) A-I      intronic chr16:84805265(+) A-I      intronic chr16:84804608(+) A-I      intronic chr16:84804467(+) A-I      intronic chr16:84786642(+) A-I      intronic chr16:84783983(+) A-I      intronic chr16:84783854(+) A-I      intronic chr16:84783853(+) A-I      intronic chr16:84783832(+) A-I      intronic chr16:84783742(+) A-I      intronic chr16:84783740(+) A-I      intronic chr16:84782162(+) A-I      intronic chr16:84782110(+) A-I      intronic chr16:84782014(+) A-I      intronic chr16:84781974(+) A-I      intronic chr16:84781953(+) A-I      intronic chr16:84781681(+) A-I      intronic chr16:84781680(+) A-I      intronic chr16:84781649(+) A-I      intronic chr16:84781573(+) A-I      intronic chr16:84781570(+) A-I      intronic chr16:84781556(+) A-I      intronic chr16:84781547(+) A-I      intronic chr16:84781542(+) A-I      intronic chr16:84781353(+) A-I      intronic chr16:84781234(+) A-I      intronic chr16:84781224(+) A-I      intronic chr16:84756327(+) A-I      intronic chr16:84752681(+) A-I      intronic chr16:84752674(+) A-I      intronic chr16:84752660(+) A-I      intronic chr16:84752659(+) A-I      intronic chr16:84752581(+) A-I      intronic chr16:84752268(+) A-I      intronic chr16:84752264(+) A-I      intronic chr16:84752243(+) A-I      intronic chr16:84752242(+) A-I      intronic chr16:84752186(+) A-I      intronic chr16:84752118(+) A-I      intronic chr16:84742034(+) A-I      intronic chr16:84742012(+) A-I      intronic chr16:84741976(+) A-I      intronic chr16:84741936(+) A-I      intronic chr16:84741903(+) A-I      intronic chr16:84741898(+) A-I      intronic chr16:84741877(+) A-I      intronic chr16:84741846(+) A-I      intronic chr16:84741800(+) A-I      intronic chr16:84740276(+) A-I      intronic chr16:84740211(+) A-I      intronic chr16:84739763(+) A-I      intronic chr16:84739525(+) A-I      intronic chr16:84739508(+) A-I      intronic chr16:84739426(+) A-I      intronic chr16:84739099(+) A-I      intronic chr16:84739098(+) A-I      intronic chr16:84739084(+) A-I      intronic chr16:84739024(+) A-I      intronic chr16:84739003(+) A-I      intronic chr16:84738999(+) A-I      intronic chr16:84738983(+) A-I      intronic chr16:84738977(+) A-I      intronic chr16:84738964(+) A-I      intronic chr16:84738942(+) A-I      intronic chr16:84738938(+) A-I      intronic chr16:84739044(+) A-I      intronic chr16:84808194(+) A-I      intronic chr16:84739377(+) A-I      intronic chr16:84752462(+) A-I      intronic chr16:84739443(+) A-I      intronic chr16:84789193(+) A-I      intronic chr16:84805677(+) A-I      intronic chr16:84807680(+) A-I      intronic chr16:84807735(+) A-I      intronic chr16:84756199(+) A-I      intronic chr16:84752565(+) A-I      intronic chr16:84781270(+) A-I      intronic chr16:84752184(+) A-I      intronic chr16:84752516(+) A-I      intronic chr16:84740328(+) A-I      intronic chr16:84770625(+) A-I      intronic chr16:84810593(+) A-I      intronic chr16:84805327(+) A-I      intronic chr16:84739036(+) A-I      intronic chr16:84756311(+) A-I      intronic chr16:84781779(+) A-I      intronic chr16:84805322(+) A-I      intronic chr16:84741593(+) A-I      intronic chr16:84739412(+) A-I      intronic chr16:84781315(+) A-I      intronic chr16:84807679(+) A-I      intronic chr16:84752438(+) A-I      intronic chr16:84741895(+) A-I      intronic chr16:84789300(+) A-I      intronic chr16:84741520(+) A-I      intronic chr16:84783926(+) A-I      intronic chr16:84807745(+) A-I      intronic chr16:84752282(+) A-I      intronic chr16:84741970(+) A-I      intronic chr16:84807762(+) A-I      intronic chr16:84782090(+) A-I      intronic chr16:84805783(+) A-I      intronic chr16:84781296(+) A-I      intronic chr16:84736417(+) A-I      intronic chr16:84752115(+) A-I      intronic chr16:84805909(+) A-I      intronic chr16:84805363(+) A-I      intronic chr16:84756248(+) A-I      intronic chr16:84781309(+) A-I      intronic chr16:84807837(+) A-I      intronic chr16:84781231(+) A-I      intronic chr16:84736457(+) A-I      intronic chr16:84741456(+) A-I      intronic chr16:84805315(+) A-I      intronic chr16:84804522(+) A-I      intronic chr16:84807703(+) A-I      intronic chr16:84740420(+) A-I      intronic chr16:84740345(+) A-I      intronic chr16:84781961(+) A-I      intronic chr16:84810519(+) A-I      intronic chr16:84741914(+) A-I      intronic chr16:84805919(+) A-I      intronic chr16:84755469(+) A-I      intronic chr16:84805219(+) A-I      intronic chr16:84808327(+) A-I      intronic chr16:84808116(+) A-I      intronic chr16:84742007(+) A-I      intronic chr16:84739419(+) A-I      intronic chr16:84807594(+) A-I      intronic chr16:84741909(+) A-I      intronic chr16:84805711(+) A-I      intronic chr16:84752303(+) A-I      intronic chr16:84782093(+) A-I      intronic chr16:84752608(+) A-I      intronic chr16:84741563(+) A-I      intronic chr16:84781188(+) A-I      intronic chr16:84739723(+) A-I      intronic chr16:84782049(+) A-I      intronic chr16:84745591(+) A-I      intronic chr16:84783954(+) A-I      intronic chr16:84783903(+) A-I      intronic chr16:84783852(+) A-I      intronic chr16:84752183(+) A-I      intronic chr16:84808206(+) A-I      intronic chr16:84752308(+) A-I      intronic chr16:84783928(+) A-I      intronic chr16:84781190(+) A-I      intronic chr16:84805274(+) A-I      intronic chr16:84786840(+) A-I      intronic chr16:84736452(+) A-I      intronic chr16:84735569(+) A-I      intronic chr16:84804620(+) A-I      intronic chr16:84783126(+) A-I      intronic chr16:84743656(+) A-I      intronic chr16:84743765(+) A-I      intronic chr16:84752160(+) A-I      intronic chr16:84789962(+) A-I      intronic chr16:84781356(+) A-I      intronic chr16:84741528(+) A-I      intronic chr16:84808252(+) A-I      intronic chr16:84735863(+) A-I      intronic chr16:84751977(+) A-I      intronic chr16:84739754(+) A-I      intronic chr16:84783867(+) A-I      intronic chr16:84781571(+) A-I      intronic chr16:84738955(+) A-I      intronic chr16:84807828(+) A-I      intronic chr16:84781299(+) A-I      intronic chr16:84805762(+) A-I      intronic chr16:84781393(+) A-I      intronic chr16:84807736(+) A-I      intronic chr16:84741470(+) A-I      intronic chr16:84781247(+) A-I      intronic chr16:84752499(+) A-I      intronic chr16:84805242(+) A-I      intronic chr16:84810442(+) A-I      intronic chr16:84805797(+) A-I      intronic chr16:84752175(+) A-I      intronic chr16:84781581(+) A-I      intronic chr16:84752498(+) A-I      intronic chr16:84781295(+) A-I      intronic chr16:84781639(+) A-I      intronic chr16:84739514(+) A-I      intronic chr16:84736434(+) A-I      intronic chr16:84805840(+) A-I      intronic chr16:84783893(+) A-I      intronic chr16:84739405(+) A-I      intronic chr16:84740353(+) A-I      intronic chr16:84756261(+) A-I      intronic chr16:84742002(+) A-I      intronic chr16:84807717(+) A-I      intronic chr16:84810558(+) A-I      intronic chr16:84805236(+) A-I      intronic chr16:84782039(+) A-I      intronic chr16:84781762(+) A-I      intronic chr16:84741801(+) A-I      intronic chr16:84781688(+) A-I      intronic chr16:84781653(+) A-I      intronic chr16:84805837(+) A-I      intronic chr16:84741523(+) A-I      intronic chr16:84739004(+) A-I      intronic chr16:84805938(+) A-I      intronic chr16:84736478(+) A-I      intronic chr16:84743783(+) A-I      intronic chr16:84807768(+) A-I      intronic chr16:84739511(+) A-I      intronic chr16:84756247(+) A-I      intronic chr16:84805273(+) A-I      intronic chr16:84808337(+) A-I      intronic chr16:84781373(+) A-I      intronic chr16:84804117(+) A-I      intronic chr16:84805376(+) A-I      intronic chr16:84735829(+) A-I      intronic chr16:84781617(+) A-I      intronic chr16:84807765(+) A-I      intronic chr16:84756436(+) A-I      intronic chr16:84805319(+) A-I      intronic chr16:84805682(+) A-I      intronic chr16:84743629(+) A-I      intronic chr16:84783859(+) A-I      intronic chr16:84756346(+) A-I      intronic chr16:84756340(+) A-I      intronic chr16:84782009(+) A-I      intronic chr16:84781610(+) A-I      intronic chr16:84805316(+) A-I      intronic chr16:84783894(+) A-I      intronic chr16:84741430(+) A-I      intronic chr16:84743755(+) A-I      intronic chr16:84739608(+) A-I      intronic chr16:84783907(+) A-I      intronic chr16:84752678(+) A-I      intronic chr16:84756349(+) A-I      intronic chr16:84752478(+) A-I      intronic chr16:84782075(+) A-I      intronic chr16:84752595(+) A-I      intronic chr16:84805314(+) A-I      intronic chr16:84741905(+) A-I      intronic chr16:84783935(+) A-I      intronic chr16:84756191(+) A-I      intronic chr16:84752473(+) A-I      intronic chr16:84805896(+) A-I      intronic chr16:84752274(+) A-I      intronic chr16:84808283(+) A-I      intronic chr16:84781360(+) A-I      intronic chr16:84805367(+) A-I      intronic chr16:84739039(+) A-I      intronic chr16:84741935(+) A-I      intronic chr16:84741900(+) A-I      intronic chr16:84738857(+) A-I      intronic chr16:84752672(+) A-I      intronic chr16:84781763(+) A-I      intronic chr16:84808216(+) A-I      intronic chr16:84780064(+) A-I      intronic chr16:84756351(+) A-I      intronic chr16:84808349(+) A-I      intronic chr16:84784659(+) A-I      intronic chr16:84752110(+) A-I      intronic chr16:84783131(+) A-I      intronic chr16:84741403(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	USP10	chr16:84788485(+) A-I intron -    21960545 chr16:84781247(+) A-G intron -    22484847 chr16:84781295(+) A-G intron -    22484847 chr16:84781299(+) A-G intron -    22484847 chr16:84781309(+) A-G intron -    22484847 chr16:84781571(+) A-G intron -    22484847 chr16:84789193(+) A-G intron -    22484847 chr16:84804620(+) A-G intron -    22484847 chr16:84805363(+) A-G intron -    22484847 chr16:84805367(+) A-G intron -    22484847 chr16:84805783(+) A-G intron -    22484847 chr16:84805840(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	USP10	chr16:84778284-84778285(+) m6A 3'UTR//CDS//exon//intron       24981863 chr16:84778306-84778307(+) m6A 3'UTR//CDS//exon//intron       24981863 chr16:84778337-84778338(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863//22608085 chr16:84778521-84778522(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84778646-84778647(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84778708-84778709(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84778727-84778728(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84778736-84778737(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84778798-84778799(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84778871-84778872(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr16:84778885-84778886(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr16:84778928-84778929(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84778947-84778948(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84779018-84779019(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84779024-84779025(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84779034-84779035(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr16:84779170-84779171(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr16:84792352-84792353(+) m6A 3'UTR//CDS//intron       - chr16:84796641-84796642(+) m6A 3'UTR//CDS//exon       27773535 chr16:84796661-84796662(+) m6A 3'UTR//CDS//exon       27773535 chr16:84797718-84797719(+) m6A 3'UTR//CDS//exon       27773535 chr16:84797749-84797750(+) m6A 3'UTR//CDS//exon       24981863//27773535 chr16:84797779-84797780(+) m6A 3'UTR//CDS//intron       24981863//27773535 chr16:84797796-84797797(+) m6A 3'UTR//CDS//intron       24981863//27773535 chr16:84797801-84797802(+) m6A 3'UTR//CDS//intron       24981863//27773535 chr16:84797834-84797835(+) m6A 3'UTR//CDS//intron       24981863 chr16:84812595-84812596(+) m6A 3'UTR//CDS       24284625 chr16:84812630-84812631(+) m6A 3'UTR//CDS       24284625 chr16:84812677-84812678(+) m6A 3'UTR//CDS       24284625 chr16:84812688-84812689(+) m6A 3'UTR       24284625 chr16:84812731-84812732(+) m6A 3'UTR       24284625//24981863 chr16:84812783-84812784(+) m6A 3'UTR       24284625//24981863//22608085 chr16:84812895-84812896(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr16:84812930-84812931(+) m6A 3'UTR       24284625//24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-505-3p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Primary dendritic cells|T cell line (J77)     21505438 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	USP10	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome-free cytosol Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-505-3p	4-Thiazolidinone, 3-(1-phenylethyl)-2-thioxo- 99773 Drug sensitive Sensorad 99342 Drug sensitive Curcumin 969516 Drug sensitive 5-Iodo-8-quinolinol 96111 Drug sensitive Hydrazinecarboximidamide, 2,2'-(carbonylbis(imino-3,1-phenyleneethylidyne))bis-, hydrochloride 9577144 Drug sensitive Actinomycin X4357G methoxime 9573583 Drug sensitive [[4-(3-Aminophenyl)-2-pyridyl]methyleneamino]thiourea 9556427 Drug sensitive 4-(1,3-Benzoxazol-2-yl)aniline 88733 Drug sensitive L-2-Aminobutyric acid 80283 Drug sensitive Arjunolic acid 73641 Drug sensitive Morpholine-N-dithiocarbamate 72675 Drug sensitive 4,4'-Bis(dimethylamino)thiobenzophenone 71045 Drug sensitive Tolonium chloride 7083 Drug sensitive Azure B 68275 Drug sensitive Melicopidine 68060 Drug sensitive Sulbentine 67686 Drug sensitive 3-Hydroxy-3'-nitro-2-naphthanilide 67277 Drug sensitive Baccharinoid B4 6711263 Drug sensitive Reactive Blue 2 656725 Drug sensitive Indazole analogue 17 6539599 Drug sensitive N-(6-Phenyl-1H-indazol-3-yl)cyclopropanecarboxamide 6539593 Drug sensitive Baccatin III 65366 Drug sensitive Ixabepilone 6445540 Drug sensitive Methylene blue 6099 Drug sensitive Piriqualone 6015423 Drug sensitive Verrucarin A, 3'-(acetyloxy)-7'-deoxo-2'-deoxy-4'-hydroxy-7'-(1-hydroxyethyl)- 5933240 Drug sensitive 3-[[4-[[2-(Methoxycarbonylamino)-3H-benzimidazol-5-yl]oxy]phenyl]carbamoylamino]benzoic acid;hydrochloride 57399799 Drug sensitive 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive (3beta)-3-((4-O-beta-D Glucopyranosyl-beta-D-xylopyranosyl)oxy)-14-hydroxy-19-oxocarda-4,20(22)-dienolide 56840951 Drug sensitive Antibiotic 1907-VIII 5477807 Drug sensitive 8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive Artelasticin 5471311 Drug sensitive Antineoplastic-643001 5466797 Drug sensitive Withacnistin 54606507 Drug sensitive 2, 2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-, trihydrochloride 54600704 Drug sensitive Dysorone E 5459221 Drug sensitive Thiram 5455 Drug sensitive (E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive (1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive Indanthren Corinth RK 5351878 Drug sensitive Dihydro-5-azacytidine 5351280 Drug sensitive 5-Methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 Drug sensitive 5-[2-(4-Hydroxy-2,6-dimethylphenyl)ethenyl]pyridine-3-carboxamide 53239975 Drug sensitive Rhamnazin 5320945 Drug sensitive Centaureidin 5315773 Drug sensitive Peridinin 5289155 Drug sensitive 8-Hydroxymanzamine A 5270765 Drug sensitive Spiperone 5265 Drug resistant Kekule 499328 Drug sensitive Ammonia; dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498559 Drug sensitive Pipamperone 4830 Drug sensitive 1-[2-(3-Chlorophenyl)-2-oxoethyl]-2-acetylbenzimidazole 46911792 Drug sensitive Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive N-Methyl-1,5-bis(4-cyanophenoxy)-3-aza-pentane 45028719 Drug sensitive Isopinnatal 44558939 Drug sensitive 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Neriifolin 441867 Drug sensitive Isobrucein A 441802 Drug sensitive Glaucarubinone 441796 Drug sensitive Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide 42640 Drug sensitive S-(Diethylarsino)-3-mercapto-1,2-propanediol 406476 Drug sensitive Ethanone, 1-[3-(bromomethyl)-1,4-dioxido-2-quinoxalinyl]- 404859 Drug sensitive 2-[(Phenylamino)methyl]benzene-1,4-diol 403336 Drug sensitive 3-[(2-Bromoacetyl)amino]-N-carbamoylbenzamide 398525 Drug sensitive Phosphine, 1,2-ethanediylbis[bis[2-(methylthio)phenyl]- 397601 Drug sensitive Lomustine 3950 Drug sensitive Amino MMI-S02 CI 393532 Drug sensitive Sjg-136 393111 Drug sensitive 2-Amino-4-(2-hydroxy-4-methylphenyl)-5-phenylpyrimidine 392744 Drug sensitive 15-Oxozoapatlin 391317 Drug sensitive Isopropyl 4-(2-(4-bromo-2,5-dihydroxyphenyl)ethyl)benzoate 389288 Drug sensitive Cardenolide 2 388098 Drug sensitive Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug sensitive 2-(1-Propynyl)estradiol 388008 Drug sensitive L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive 4-Methylthio-N-(3,4,5-trimethoxybenzyl)aniline 373808 Drug sensitive N-Hydroxy-N-methylpropanethioamide 371713 Drug sensitive Antineoplastic-645804 371505 Drug sensitive 11H-Benzo[a]carbazole-1,4-dione, 7,11-dimethyl- 371271 Drug sensitive Sanguilutine pseudobase 371258 Drug sensitive Tetrakis(8-chinolineolato)titanium(IV)-tetrahydrochloride 368279 Drug sensitive Tris(tropolonato)samarium(III) 366262 Drug sensitive [1-(2-Benzyl-3-methoxy-5-oxo-2H-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl] 1-[1-[2-[[2-[[2-(dimethylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylate 357989 Drug sensitive 1-Chloro-3-(3-chloropropylsulfonylsulfanyl)propane 355643 Drug sensitive Maxima isoflavone D 343081 Drug sensitive 2-Isopropenyl-4,6-diphenoxy-1,3,5-triazine 340916 Drug sensitive 4-Selenazolecarboxamide, 2-beta-D-ribofuranosyl- 334706 Drug sensitive Phenyl gallate 333279 Drug sensitive Zonarol 332671 Drug sensitive Mercury, (p-carboxyphenyl)(purin-6-ylthio)- 3246339 Drug sensitive 2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive Stannane, trimethyl[(4-morpholinylthioxomethyl)thio]- 300936 Drug sensitive 2-Hydroxy-4-((2,4,6-triamino-5-pyrimidinyl)diazenyl)phenylarsonic acid 272658 Drug sensitive Digoxin 2724385 Drug sensitive (15S)-15-Ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one 2724040 Drug sensitive 3,6-Dibromophenanthrene-9,10-dione 258450 Drug sensitive 3-[(1R)-1-(2-Chlorophenyl)ethoxy]-5-{6-[(2S)-2,3-dihydroxypropoxy]-1H-1,3-benzodiazol-1-yl}thiophene-2-carboxamide 25263120 Drug sensitive 3-[(2-Chlorophenyl)methoxy]-5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)thiophene-2-carboxamide 25263092 Drug sensitive 2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide 25023715 Drug resistant 1-(3-Bromo-phenyl)-3-(pyridin-2-ylsulfanyl)-propenone 24203485 Drug sensitive 2-[4-(Methoxy)phenyltio]-3-phenyl-5,7-diamino quinoxaline 24203447 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive Sodium 2-(4-((7-chloro-2-quinoxalinyl)oxy)phenoxy)propionate 23675947 Drug sensitive [(1R,2S,4R,6R,7R,10S,11R,14S,16S)-16-Hydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-14-yl] acetate 23618199 Drug sensitive (1S,2R,5Z,10R,11S,12R,16S)-2-Hydroxy-2,6,10-trimethyl-15-methylidene-13,18-dioxatricyclo[9.6.1.012,16]octadec-5-en-14-one 23425613 Drug sensitive Scillirosidin, glycoside 222160 Drug sensitive (1S,3R,7Z,9R,12S,13R,15R)-13-Hydroxy-3,7,12-trimethyl-13-prop-1-en-2-yl-10,14,16-trioxatetracyclo[7.5.1.13,6.012,15]hexadeca-5,7-diene-4,11-dione 20835084 Drug sensitive 8-Hydroxyquinoline 1923 Drug sensitive Sudan II 18386 Drug sensitive Butyltriphenylphosphonium bromide 159628 Drug sensitive Arsenic trioxide 14888 Drug sensitive Methyl 3,4-dichloro-5-nitro-2-furoate 147711 Drug sensitive (5S,10S,13R,14S)-3-[3,4-Dihydroxy-6-methyl-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,14-dihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde 146156945 Drug sensitive Dtxsid30327893 138402823 Drug sensitive Acid Alizarine Red B 135565636 Drug sensitive 6-Aryl-pyrazolo[3,4-b]pyridine analogue 23 135435015 Drug sensitive (1R,2S,5S,8S,9S,17R,18R,21S,24R,26S,27S)-14-Chloro-5,15-dihydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacos-11-ene-4,10,22,29-tetrone 134715214 Drug sensitive Methyl (1S,10R,11S,12S)-11-acetyloxy-12-ethyl-4-[(13R,15R,17R)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 133126830 Drug sensitive Actinomycin D, 93% 131954673 Drug sensitive Dibutyltin dichloride 12688 Drug sensitive Triphenyltin chloride 12540 Drug sensitive Berberine chloride 12456 Drug sensitive (2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive Benzyl trisulfide 122842 Drug sensitive Homovinblastine methanesulfonate salt 11970002 Drug sensitive Melampodinin 11953936 Drug sensitive Unii-C616DV5Y11 117587576 Drug sensitive Neoambrosin 11128594 Drug sensitive p-Toluquinone 11122 Drug sensitive Unii-9JU14BJ5QG 109374088 Drug sensitive Capri Blue 102162 Drug sensitive (1S,3R,6R,12S,14R,15S,18R,19E,21Z,25R,26S,27R)-6,15-Dihydroxy-18-[(1R)-1-hydroxyethyl]-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione 101307863 Drug sensitive Chimaphilin 101211 Drug sensitive 1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant (1s,2e,4r,7e,11e)-4-hydroxy-2,7,11-cembratrien-6-one - Drug sensitive (1s,2e,4s,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug sensitive (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-5-(3-methyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole - Drug sensitive (Z)-5-chloro-3-((1-(3,5-dimethoxyphenyl)-9H-pyrido[3,4-b]indol-3-yl)methylene)indolin-2-one - Drug sensitive 1,2-benzisothiazoline-3-thione, 2-methyl- (8ci) - Drug sensitive 1,3,5-triazin-2-amine, 4,6-dimethoxy-n-phenyl- - Drug sensitive 1,3-isoquinolinedione, 4-[(3,4-dimethoxyphenyl)methylene]- - Drug sensitive 1,6,7,8-tetra-o-phenylcarbamoylcastnospermine - Drug sensitive 1,8-naphthyridin-4(1h)-one, 2-(3-chlorophenyl)-5-methyl- - Drug sensitive 1,8-naphthyridin-4(1h)-one, 2-(4-fluorophenyl)-5-methyl- - Drug sensitive 2-(4-(methylsulfonyl)phenyl)-6-p-tolyl-4,5-dihydropyridazin-3(2H)-one - Drug sensitive 2,4-diethoxyestra-1,3,5(10)trien-3,17.beta.-diol - Drug sensitive 2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive 2k2S,S? - Drug sensitive 3,19-(2,6-dimethyoxy)benzylidineandrographolide - Drug sensitive 3,19-(4-n,n-dimethylamino)benzylidineandrographolide - Drug sensitive 4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive 5-[2-(4-methoxyphenyl)ethyl]-1,2,3-dimethoxy benzene - Drug sensitive 5-chloro-1-(7-chloro-3-methyl-1,4-dioxyquinoxalin-2-yl)-5-(3,4,5-trimethoxy)-penta-2,4-dien-1-one - Drug sensitive 9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 2-phenyl- - Drug sensitive aceanthryleno[1,2-b]quinoxaline, 12-nitro- - Drug sensitive aquatris(1,3-diphenylpropane-1,3-dionato)neodymium(iii) - Drug sensitive benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive c4, carbonyl, ethyl prodigiosine - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive gold(1+), bis(trimethylphosphine)-, chloride - Drug sensitive inosine, 6-thio-, 2',3',5'-tris(4-methoxybenzoate) - Drug sensitive l-cysteine, s-[(4-methylphenyl)diphenylmethyl]- (9ci) - Drug sensitive phosphonium, (3-bromopropyl)triphenyl- bromide - Drug sensitive phosphonium, 1,8-octanediylbis[triphenyl-, diiodide - Drug sensitive piceatannol, 4,3',5'-trimethyl,1s0 - Drug sensitive piperazine-2,2,5,5-tetracarbonitrile, 3,6-dipropyl- - Drug sensitive purine, 2,6,8-tris(hexylamino)- - Drug sensitive roridin a, 8-hydroxy-9b,10b-epoxy- - Drug sensitive thiazolo[3,2-f]phenanthridinium, 3-phenyl- perchlorate - Drug sensitive urea, n'-(5,6-dichloro-1h-benzimidazol-2-yl)-n,n-dimethyl- - Drug sensitive (s)(-)-methyl perillate - Drug sensitive (Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive 2-(4-hydroxy-benzylidene)-2-(2-pyridyl)acetonitrile - Drug sensitive 2-amino-5-chloro-6-(2-thiazolyloxy)-benzimidazole - Drug sensitive 2-oxo-N-(pyridin-4-yl)-2-(1-tosyl-1H-indol-3-yl)acetamide - Drug sensitive 4-carbo-1-thiazolidine-3-o-gluconyl-.gamma.-lactone - Drug sensitive 5-methoxy camptothecin - Drug sensitive 9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive antineoplastic-615538 - Drug sensitive antineoplastic-644916 - Drug sensitive Copper(II) complex with a thiosemicarbazone as a ligand - Drug sensitive dichlorobisoxinatotitanium(iv) - Drug sensitive his 47-methyl ct - Drug sensitive methyl 3-farnesylthioacetate - Drug sensitive n-acetyl-4-s-cystaminyl phenol - Drug sensitive n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive phenylmercuric acetate (usan) - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-505-3p	D-Glucose 5793 Drug interaction    RC00005735 Sunitinib 5329102 Drug interaction    RC00005738 Doxorubicin 31703 Drug interaction    RC00005736 Verapamil 2520 Drug interaction    RC00005734 Gefitinib 123631 Drug interaction    RC00005737 Chemotherapy - Drug interaction    RC00008872

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-505-3p
Interactor2: USP10

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.