Basic Information:

  VIRBase ID:  

HHID00059807

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-502-5p:  MIMAT0002873          RBM27:  NM_018989     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-502-5p	RBM27
miRBase Accession/Entrez ID	MIMAT0002873	54439
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ARRS1//Psc1//ZC3H18//ZC3H20

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-502-5p	rs1557183210 chrX:50014624    C/G rs1557183213 chrX:50014627    G/A rs1557183214 chrX:50014629    T/C rs1557183215 chrX:50014631    C/A rs373544813 chrX:50014622    A/G rs782505645 chrX:50014626    G/T rs1557183206 chrX:50014617    T/C rs1557183207 chrX:50014620    C/A rs1557183207 chrX:50014620    C/G rs782685418 chrX:50014616    C/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RBM27	chr5:145617907(+) A-I      intronic chr5:145617896(+) A-I      intronic chr5:145617892(+) A-I      intronic chr5:145617886(+) A-I      intronic chr5:145617825(+) A-I      intronic chr5:145617817(+) A-I      intronic chr5:145617434(+) A-I      intronic chr5:145615492(+) A-I      intronic chr5:145615488(+) A-I      intronic chr5:145615380(+) A-I      intronic chr5:145615305(+) A-I      intronic chr5:145615107(+) A-I      intronic chr5:145614957(+) A-I      intronic chr5:145614935(+) A-I      intronic chr5:145614923(+) A-I      intronic chr5:145614863(+) A-I      intronic chr5:145614847(+) A-I      intronic chr5:145591745(+) A-I      intronic chr5:145591719(+) A-I      intronic chr5:145591683(+) A-I      intronic chr5:145591125(+) A-I      intronic chr5:145591122(+) A-I      intronic chr5:145590792(+) A-I      intronic chr5:145590716(+) A-I      intronic chr5:145587711(+) A-I      intronic chr5:145586285(+) A-I      intronic chr5:145586264(+) A-I      intronic chr5:145586244(+) A-I      intronic chr5:145674963(+) A-I      intronic chr5:145616397(+) A-I      intronic chr5:145643888(+) A-I      intronic chr5:145653965(+) A-I      intronic chr5:145628999(+) A-I      intronic chr5:145659195(+) A-I      intronic chr5:145659194(+) A-I      intronic chr5:145652217(+) A-I      intronic chr5:145652205(+) A-I      intronic chr5:145652182(+) A-I      intronic chr5:145652165(+) A-I      intronic chr5:145643881(+) A-I      intronic chr5:145643847(+) A-I      intronic chr5:145643810(+) A-I      intronic chr5:145643555(+) A-I      intronic chr5:145643412(+) A-I      intronic chr5:145643406(+) A-I      intronic chr5:145639660(+) A-I      intronic chr5:145639089(+) A-I      intronic chr5:145639088(+) A-I      intronic chr5:145639087(+) A-I      intronic chr5:145638952(+) A-I      intronic chr5:145638869(+) A-I      intronic chr5:145629925(+) A-I      intronic chr5:145629910(+) A-I      intronic chr5:145629893(+) A-I      intronic chr5:145629883(+) A-I      intronic chr5:145629865(+) A-I      intronic chr5:145629130(+) A-I      intronic chr5:145629096(+) A-I      intronic chr5:145616384(+) A-I      intronic chr5:145616396(+) A-I      intronic chr5:145629063(+) A-I      intronic chr5:145674998(+) A-I      intronic chr5:145674973(+) A-I      intronic chr5:145674968(+) A-I      intronic chr5:145663025(+) A-I      intronic chr5:145629053(+) A-I      intronic chr5:145628684(+) A-I      intronic chr5:145628674(+) A-I      intronic chr5:145628272(+) A-I      intronic chr5:145628158(+) A-I      intronic chr5:145628042(+) A-I      intronic chr5:145626167(+) A-I      intronic chr5:145623802(+) A-I      intronic chr5:145623782(+) A-I      intronic chr5:145622749(+) A-I      intronic chr5:145622669(+) A-I      intronic chr5:145622619(+) A-I      intronic chr5:145622600(+) A-I      intronic chr5:145622574(+) A-I      intronic chr5:145622573(+) A-I      intronic chr5:145622382(+) A-I      intronic chr5:145622370(+) A-I      intronic chr5:145622212(+) A-I      intronic chr5:145622176(+) A-I      intronic chr5:145621766(+) A-I      intronic chr5:145621242(+) A-I      intronic chr5:145621076(+) A-I      intronic chr5:145620047(+) A-I      intronic chr5:145620015(+) A-I      intronic chr5:145619994(+) A-I      intronic chr5:145619990(+) A-I      intronic chr5:145619989(+) A-I      intronic chr5:145703622(+) A-I      intronic chr5:145628610(+) A-I      intronic chr5:145628625(+) A-I      intronic chr5:145628686(+) A-I      intronic chr5:145628711(+) A-I      intronic chr5:145639755(+) A-I      intronic chr5:145639759(+) A-I      intronic chr5:145639774(+) A-I      intronic chr5:145639777(+) A-I      intronic chr5:145663045(+) A-I      intronic chr5:145696896(+) A-I      intronic chr5:145676406(+) A-I      intronic chr5:145619959(+) A-I      intronic chr5:145663015(+) A-I      intronic chr5:145663003(+) A-I      intronic chr5:145662985(+) A-I      intronic chr5:145661837(+) A-I      intronic chr5:145660621(+) A-I      intronic chr5:145660582(+) A-I      intronic chr5:145660570(+) A-I      intronic chr5:145660521(+) A-I      intronic chr5:145659892(+) A-I      intronic chr5:145659841(+) A-I      intronic chr5:145659818(+) A-I      intronic chr5:145659702(+) A-I      intronic chr5:145659686(+) A-I      intronic chr5:145643585(+) A-I      intronic chr5:145674819(+) A-I      intronic chr5:145585461(+) A-I      intronic chr5:145638461(+) A-I      intronic chr5:145592342(+) A-I      intronic chr5:145643626(+) A-I      intronic chr5:145615363(+) A-I      intronic chr5:145628735(+) A-I      intronic chr5:145591184(+) A-I      intronic chr5:145661734(+) A-I      intronic chr5:145659228(+) A-I      intronic chr5:145623858(+) A-I      intronic chr5:145622595(+) A-I      intronic chr5:145659696(+) A-I      intronic chr5:145628163(+) A-I      intronic chr5:145619274(+) A-I      intronic chr5:145639715(+) A-I      intronic chr5:145659801(+) A-I      intronic chr5:145628168(+) A-I      intronic chr5:145615274(+) A-I      intronic chr5:145613701(+) A-I      intronic chr5:145621605(+) A-I      intronic chr5:145617924(+) A-I      intronic chr5:145590763(+) A-I      intronic chr5:145639024(+) A-I      intronic chr5:145586942(+) A-I      intronic chr5:145646308(+) A-I      intronic chr5:145629170(+) A-I      intronic chr5:145629087(+) A-I      intronic chr5:145661816(+) A-I      intronic chr5:145614959(+) A-I      intronic chr5:145608267(+) A-I      intronic chr5:145586273(+) A-I      intronic chr5:145661653(+) A-I      intronic chr5:145628129(+) A-I      intronic chr5:145628599(+) A-I      intronic chr5:145629048(+) A-I      intronic chr5:145628780(+) A-I      intronic chr5:145629050(+) A-I      intronic chr5:145622628(+) A-I      intronic chr5:145587383(+) A-I      intronic chr5:145659113(+) A-I      intronic chr5:145622226(+) A-I      intronic chr5:145674877(+) A-I      intronic chr5:145601154(+) A-I      intronic chr5:145652138(+) A-I      intronic chr5:145643610(+) A-I      intronic chr5:145658850(+) A-I      intronic chr5:145628195(+) A-I      intronic chr5:145638821(+) A-I      intronic chr5:145658758(+) A-I      intronic chr5:145659170(+) A-I      intronic chr5:145623824(+) A-I      intronic chr5:145629100(+) A-I      intronic chr5:145622682(+) A-I      intronic chr5:145656436(+) A-I      intronic chr5:145616643(+) A-I      intronic chr5:145629205(+) A-I      intronic chr5:145629142(+) A-I      intronic chr5:145615438(+) A-I      intronic chr5:145621243(+) A-I      intronic chr5:145659872(+) A-I      intronic chr5:145638391(+) A-I      intronic chr5:145615390(+) A-I      intronic chr5:145659782(+) A-I      intronic chr5:145586328(+) A-I      intronic chr5:145615392(+) A-I      intronic chr5:145639701(+) A-I      intronic chr5:145620029(+) A-I      intronic chr5:145586223(+) A-I      intronic chr5:145614335(+) A-I      intronic chr5:145643482(+) A-I      intronic chr5:145659321(+) A-I      intronic chr5:145606011(+) A-I      intronic chr5:145652109(+) A-I      intronic chr5:145628768(+) A-I      intronic chr5:145586158(+) A-I      intronic chr5:145659786(+) A-I      intronic chr5:145622296(+) A-I      intronic chr5:145585432(+) A-I      intronic chr5:145675834(+) A-I      intronic chr5:145617950(+) A-I      intronic chr5:145605652(+) A-I      intronic chr5:145590732(+) A-I      intronic chr5:145624454(+) A-I      intronic chr5:145659093(+) A-I      intronic chr5:145586309(+) A-I      intronic chr5:145617274(+) A-I      intronic chr5:145591211(+) A-I      intronic chr5:145658840(+) A-I      intronic chr5:145670549(+) A-I      intronic chr5:145662853(+) A-I      intronic chr5:145619145(+) A-I      intronic chr5:145626119(+) A-I      intronic chr5:145614956(+) A-I      intronic chr5:145654951(+) A-I      intronic chr5:145628645(+) A-I      intronic chr5:145629029(+) A-I      intronic chr5:145659804(+) A-I      intronic chr5:145646377(+) A-I      intronic chr5:145608243(+) A-I      intronic chr5:145613707(+) A-I      intronic chr5:145628194(+) A-I      intronic chr5:145628784(+) A-I      intronic chr5:145619921(+) A-I      intronic chr5:145622286(+) A-I      intronic chr5:145674886(+) A-I      intronic chr5:145620019(+) A-I      intronic chr5:145591174(+) A-I      intronic chr5:145591819(+) A-I      intronic chr5:145629779(+) A-I      intronic chr5:145646436(+) A-I      intronic chr5:145623865(+) A-I      intronic chr5:145606071(+) A-I      intronic chr5:145662997(+) A-I      intronic chr5:145630371(+) A-I      intronic chr5:145628985(+) A-I      intronic chr5:145628678(+) A-I      intronic chr5:145629135(+) A-I      intronic chr5:145604035(+) A-I      intronic chr5:145628644(+) A-I      intronic chr5:145597478(+) A-I      intronic chr5:145586916(+) A-I      intronic chr5:145654946(+) A-I      intronic chr5:145629039(+) A-I      intronic chr5:145652026(+) A-I      intronic chr5:145675593(+) A-I      intronic chr5:145617956(+) A-I      intronic chr5:145614432(+) A-I      intronic chr5:145617380(+) A-I      intronic chr5:145585512(+) A-I      intronic chr5:145658348(+) A-I      intronic chr5:145614943(+) A-I      intronic chr5:145617914(+) A-I      intronic chr5:145630440(+) A-I      intronic chr5:145586385(+) A-I      intronic chr5:145638963(+) A-I      intronic chr5:145658949(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RBM27	chr5:145626119(+) A-I intron -    21960545 chr5:145585452(+) C-T intron -    22484847 chr5:145586158(+) A-G intron -    22484847 chr5:145586223(+) A-G intron -    22484847 chr5:145586273(+) A-G intron -    22484847 chr5:145586309(+) A-G intron -    22484847 chr5:145586328(+) A-G intron -    22484847 chr5:145586812(+) A-G intron -    22484847 chr5:145590763(+) A-G intron -    22484847 chr5:145591819(+) A-G intron -    22484847 chr5:145591860(+) A-G intron -    22484847 chr5:145592024(+) A-G intron -    22484847 chr5:145592114(+) A-G intron -    22484847 chr5:145592342(+) A-G intron -    22484847 chr5:145599786(+) A-G intron -    22484847 chr5:145599930(+) C-T intron -    22484847 chr5:145601120(+) T-C intron -    22484847 chr5:145601154(+) A-G intron -    22484847 chr5:145605317(+) T-C intron -    22484847 chr5:145606071(+) A-G intron -    22484847 chr5:145606124(+) A-G intron -    22484847 chr5:145614335(+) A-G intron -    22484847 chr5:145614943(+) A-G intron -    22484847 chr5:145614956(+) A-G intron -    22484847 chr5:145614959(+) A-G intron -    22484847 chr5:145615106(+) A-G intron -    22484847 chr5:145615274(+) A-G intron -    22484847 chr5:145615363(+) A-G intron -    22484847 chr5:145615390(+) A-G intron -    22484847 chr5:145615392(+) A-G intron -    22484847 chr5:145615438(+) A-G intron -    22484847 chr5:145615489(+) A-G intron -    22484847 chr5:145617274(+) A-G intron -    22484847 chr5:145617320(+) A-G intron -    22484847 chr5:145617847(+) A-G intron -    22484847 chr5:145617857(+) A-G intron -    22484847 chr5:145617910(+) A-G intron -    22484847 chr5:145617914(+) A-G intron -    22484847 chr5:145617950(+) A-G intron -    22484847 chr5:145617956(+) A-G intron -    22484847 chr5:145619921(+) A-G intron -    22484847 chr5:145620019(+) A-G intron -    22484847 chr5:145620029(+) A-G intron -    22484847 chr5:145622226(+) A-G intron -    22484847 chr5:145622286(+) A-G intron -    22484847 chr5:145622296(+) A-G intron -    22484847 chr5:145622435(+) A-G intron -    22484847 chr5:145622595(+) A-G intron -    22484847 chr5:145622651(+) A-G intron -    22484847 chr5:145622682(+) A-G intron -    22484847 chr5:145622761(+) A-G intron -    22484847 chr5:145623858(+) A-G intron -    22484847 chr5:145623865(+) A-G intron -    22484847 chr5:145628163(+) A-G intron -    22484847 chr5:145628168(+) A-G intron -    22484847 chr5:145628194(+) A-G intron -    22484847 chr5:145628203(+) A-G intron -    22484847 chr5:145628264(+) A-G intron -    22484847 chr5:145628585(+) A-G intron -    22484847 chr5:145628599(+) A-G intron -    22484847 chr5:145628645(+) A-G intron -    22484847 chr5:145628678(+) A-G intron -    22484847 chr5:145628710(+) A-G intron -    22484847 chr5:145628735(+) A-G intron -    22484847 chr5:145628751(+) A-G intron -    22484847 chr5:145628780(+) A-G intron -    22484847 chr5:145628781(+) A-G intron -    22484847 chr5:145628784(+) A-G intron -    22484847 chr5:145629029(+) A-G intron -    22484847 chr5:145629062(+) A-G intron -    22484847 chr5:145629100(+) A-G intron -    22484847 chr5:145629135(+) A-G intron -    22484847 chr5:145629779(+) A-G intron -    22484847 chr5:145636170(+) G-A intron -    22484847 chr5:145638821(+) A-G intron -    22484847 chr5:145650963(+) C-A intron -    22484847 chr5:145652109(+) A-G intron -    22484847 chr5:145652206(+) A-G intron -    22484847 chr5:145654946(+) A-G intron -    22484847 chr5:145654951(+) A-G intron -    22484847 chr5:145658840(+) A-G intron -    22484847 chr5:145659093(+) A-G intron -    22484847 chr5:145659228(+) A-G intron -    22484847 chr5:145659696(+) A-G intron -    22484847 chr5:145659766(+) A-G intron -    22484847 chr5:145659782(+) A-G intron -    22484847 chr5:145659786(+) A-G intron -    22484847 chr5:145659801(+) A-G intron -    22484847 chr5:145659804(+) A-G intron -    22484847 chr5:145659821(+) A-G intron -    22484847 chr5:145659872(+) A-G intron -    22484847 chr5:145660495(+) A-G intron -    22484847 chr5:145661653(+) A-G intron -    22484847 chr5:145661686(+) A-G intron -    22484847 chr5:145661752(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RBM27	chr5:145583276-145583277(+) m6A 5'UTR       24284625//24981863 chr5:145583295-145583296(+) m1A 5'UTR       26863196//26863410 chr5:145603013-145603014(+) m6A CDS       24981863 chr5:145603032-145603033(+) m6A CDS       24981863 chr5:145603053-145603054(+) m6A CDS       24981863//27773535 chr5:145608574-145608575(+) m6A CDS       24981863//27773535//22608085 chr5:145609317-145609318(+) m6A CDS       24209618//24981863//27773535//22608085 chr5:145609449-145609450(+) m6A CDS       24209618//24981863//27773535 chr5:145613247-145613248(+) m6A CDS       - chr5:145613265-145613266(+) m6A CDS       - chr5:145616890-145616891(+) m6A CDS       - chr5:145616910-145616911(+) m6A CDS       - chr5:145638141-145638142(+) m6A CDS       24981863 chr5:145640331-145640332(+) m6A CDS       24981863 chr5:145640363-145640364(+) m6A CDS       24981863 chr5:145647257-145647258(+) m6A CDS       24981863 chr5:145647265-145647266(+) m6A CDS       24981863 chr5:145647327-145647328(+) m6A CDS       24981863//27773535 chr5:145648807-145648808(+) m6A CDS       24981863//27773535//22608085 chr5:145649007-145649008(+) m6A CDS       24981863//27773535//22608085 chr5:145649013-145649014(+) m6A CDS       24981863//27773535//22608085 chr5:145649020-145649021(+) m6A CDS       24981863//27773535//22608085 chr5:145649048-145649049(+) m6A CDS       24981863//27773535//22608085 chr5:145649099-145649100(+) m6A CDS       24981863//22608085 chr5:145649135-145649136(+) m6A CDS       24981863 chr5:145651084-145651085(+) m6A CDS       22575960 chr5:145664191-145664192(+) m6A CDS       24981863 chr5:145664212-145664213(+) m6A CDS       24981863 chr5:145664268-145664269(+) m6A CDS       24981863 chr5:145665721-145665722(+) m6A 3'UTR       24284625//24981863//26404942//22575960//22608085 chr5:145665741-145665742(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22575960//22608085 chr5:145666933-145666934(+) Tm 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-502-5p	Cytoplasm GC cell lines (MKN-28|MKN-45)     30953514 Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Primary dendritic cells|T cell line (J77)     21505438 Exosome Brain tissue     23382797 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	RBM27	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome HEK-293 cells     22199352

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-502-5p	Tetrangulol 99188 Drug sensitive Midostaurin 9829523 Drug resistant (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione 98137101 Drug resistant 1-(4-Methoxyphenyl)-3-[(2-oxo-3-indolyl)amino]thiourea 947057 Drug resistant Pentamidine isethionate 8813 Drug sensitive Acridine Yellow G 8672 Drug resistant Benzethonium chloride 8478 Drug sensitive 2,4,6-Tris(2-pyridyl)-s-triazine 77258 Drug sensitive Clothixamide maleate 76972759 Drug sensitive Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive Secalonic acid D 73431 Drug sensitive o-Aminoazotoluene 7340 Drug resistant 5-Methyl-1,10-phenanthroline 72791 Drug resistant Berberine iodide 72350 Drug sensitive Coptisine chloride 72321 Drug sensitive 7-Hydroxystaurosporine 72271 Drug resistant Lauryl isoquinolinium bromide 7132 Drug sensitive Anaxirone 71218 Drug resistant Thiocoraline 70698112 Drug resistant Resorufin 69462 Drug sensitive 1-(2-Pyridylazo)-2-naphthol 6825 Drug resistant Sulbentine 67686 Drug sensitive Laurolinium acetate 67354 Drug sensitive 3-Hydroxy-3'-nitro-2-naphthanilide 67277 Drug sensitive Tacacoside A2 6712615 Drug sensitive Indazole analogue 17 6539599 Drug sensitive Tanespimycin 6505803 Drug sensitive Mevastatin 64715 Drug resistant Everolimus 6442177 Drug resistant Verrucarin A 6326658 Drug sensitive Methylene blue 6099 Drug sensitive Verrucarin A, 3'-(acetyloxy)-7'-deoxo-2'-deoxy-4'-hydroxy-7'-(1-hydroxyethyl)- 5933240 Drug sensitive N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-(1H-pyrrol-2-yl)thieno[3,2-d]pyrimidin-4-amine;hydrochloride 57401575 Drug resistant 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive 8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive Iejimalide A. 5473233 Drug sensitive 11-Cyanomethylen-11H-indolo[1,2-a]indazole 5472501 Drug resistant Antineoplastic-643001 5466797 Drug sensitive 6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive Bleomycin 5460769 Drug resistant Herveline O 5459269 Drug sensitive Thiram 5455 Drug sensitive Berberal 5351462 Drug sensitive 1-Piperidineethanol, alpha-[p-(p-chlorostyryl)phenyl]- 5351150 Drug sensitive 5-[2-(4-Hydroxy-2,6-dimethylphenyl)ethenyl]pyridine-3-carboxamide 53239975 Drug sensitive Proscillaridin 5284613 Drug resistant Purapuridine 5250 Drug resistant 5-Fluoro-2'-deoxycytidine 515328 Drug resistant Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498558 Drug sensitive Staurosporine, 98% 49831000 Drug resistant 6-Bromosangivamycin 470030 Drug resistant 9-beta-D-Xylofuranosyladenine 447916 Drug resistant Latrunculin a 445420 Drug resistant 4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine 44397453 Drug resistant 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Triciribine phosphate 43860 Drug resistant Antibiotic X-14766A 434840 Drug sensitive Bleomycin-BAPP 431594 Drug resistant Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide 42640 Drug resistant Mitoxantrone 4212 Drug resistant Menadione 4055 Drug sensitive Purpureagitosid 401298 Drug resistant 1,2 Benzo-8-(1-hydroxy-2-methylamino propane)-3-phenoxazone 400530 Drug sensitive 7,8-Dehydrocalotropin 390666 Drug resistant Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug sensitive 2-(1-Propynyl)estradiol 388008 Drug sensitive 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant Bortezomib 387447 Drug sensitive 3-(4-Fluorophenyl)-3-(4-acetoxy-2-methylphenyl)phthalide 383342 Drug resistant 19-Hydroxy-8-O-methyltetrangulol 379539 Drug sensitive 7-Chloro-6-(2-fluoroethylamino)quinoline-5,8-dione 379079 Drug sensitive 2-(3-Chloropropyloxy)naphthazarin 378771 Drug sensitive N-(8-Hydroxy-6-methyl-1,4-dioxo-1,4-dihydro-2-naphthalenyl)acetamide 377214 Drug sensitive 2-(2-(Dimethylamino)ethylamino)naphthazarin 376950 Drug sensitive 5,8-Dihydroxy-2-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]naphthalene-1,4-dione 376948 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant 2,3-Bis(dodecanoyloxy)propylarsonic acid 375754 Drug sensitive Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant 3,8,13,18,23-Pentaazapentacosane 368998 Drug sensitive Diisopropoxybis(1,4-naphthochinone-2-olato)titanium(IV) 368058 Drug sensitive 4-(1-Benzofuran-2-yl)-7-methoxychromen-2-one 364364 Drug resistant Girolline 362388 Drug resistant 1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)- 362170 Drug sensitive 7alpha-Acetoxyroylenane 362048 Drug sensitive 2,3-Dimethylbenzo[g]quinoxaline-5,10-dione 353644 Drug sensitive Acronycine, 2-nitro 342903 Drug sensitive 8-Trichloromethyldihydroberberine 320713 Drug sensitive Dasatinib 3062316 Drug resistant Deoxycamptothecin 266552 Drug resistant Gardenin A 261859 Drug resistant Antimycin A3 245869 Drug sensitive 5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive 1,2-Benzo-8-(L-alanyl)-3-phenoxazone nitrate salt 24202491 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive Antibiotic U 29135 24196291 Drug sensitive Mepacrine mustard dihydrochloride 24180972 Drug resistant Cytembena 23665583 Drug sensitive 6,7-Dimethoxy-4-(3-hydroxy-4-methylanilino)quinazoline hydrochloride 21701565 Drug resistant Kinetin riboside 20345 Drug resistant 2,2-Diethyl-6-(hydroxymethyl)-4,6,7,7a-tetrahydro-3aH-[1,3,2]dioxastannolo[4,5-c]pyran-4,7-diol 16683462 Drug sensitive Trihexyltetradecylphosphonium hexafluorophosphate 16212610 Drug sensitive Ellipticine analog 148569 Drug resistant Amphethinile 146332 Drug sensitive [(1R,5R)-16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl] acetate 146159135 Drug resistant (2R)-2-Hydroxy-3-[(6R)-11-hydroxy-2-[4-[(6R)-4-hydroxy-2-[1-hydroxy-3-[(6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-methylpropanoic acid 146158002 Drug sensitive N-[3-[(3-Amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl]-2-[(1S)-18-[(2S)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8,31-bis(1-hydroxyethyl)-26,46-dimethyl-40,43-dimethylidene-6,9,16,23,28,38,41,44,47-nonaoxo-37-propan-2-yl-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecazanonacyclo[23.23.9.329,35.12,5.112,15.119,22.154,57.01,53.032,60]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazole-4-carboxamide 146156820 Drug sensitive Astrazon Orange R 135747272 Drug sensitive C8, Carbonyl prodigiosine 135540857 Drug sensitive Formycin b 135449281 Drug resistant 4-[2-[4-(2-Methylprop-1-enyl)-2-oxoindol-3-yl]hydrazinyl]benzenesulfonamide 135409809 Drug resistant [(8Ar)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate 134694047 Drug resistant (2R,4R,6S,7S,12S)-6,7,16-Trihydroxy-18-methoxy-12-methyl-3,13-dioxatricyclo[13.4.0.02,4]nonadeca-1(15),9,16,18-tetraene-8,14-dione 131676399 Drug sensitive 1,4-Bis((2-aminoethyl)amino)-5,8-dihydroxy-9,10-anthraquinone 125982 Drug resistant 15-Deacetylsergeolide 125729 Drug sensitive Berberine chloride 12456 Drug sensitive Pepleo 122804 Drug resistant Pecilocerin A 118701034 Drug resistant Unii-C616DV5Y11 117587576 Drug sensitive Cyanoaminopyranopyridine derivatives 11494577 Drug resistant 3-Bromo-4-(3,3-dimethyl-but-1-ynyl)-2(5H)-furanone 11413833 Drug resistant (5S,7S)-5,7,9,10-Tetrahydroxy-2-methoxy-7-methyl-6,8-dihydro-5H-anthracene-1,4-dione 11209399 Drug sensitive 1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug resistant Uridine, 2'-deoxy-2'-methylene- 11075548 Drug resistant Unii-9JU14BJ5QG 109374088 Drug sensitive 9-Chloro-2-methylellipticinium acetate, hydrate 10383530 Drug resistant Withajardin C 102469053 Drug sensitive Cepharanthine 10206 Drug sensitive (1S,3R,6R,12S,14R,15S,18R,19E,21Z,25R,26S,27R)-6,15-Dihydroxy-18-[(1R)-1-hydroxyethyl]-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione 101307863 Drug sensitive Selumetinib 10127622 Drug sensitive Chimaphilin 101211 Drug sensitive (3Z,4R)-4-Hydroxy-3-[2-[(1S,3R)-3-[2-[(1S,3S,3'R,4S)-1-hydroxy-4,6,6-trimethylspiro[2,5-dioxabicyclo[2.2.2]octane-3,6'-oxane]-3'-yl]ethyl]-2,2-dimethyl-6-methylidenecyclohexyl]ethylidene]oxolan-2-one 101206903 Drug sensitive 1,3,6-triphenyl-oxazolo(5,4-d)pyrimidin-2',4(1h,3h)-dion - Drug resistant 1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant 3,7-di(trifluoromethyl)-2-furoylquioxaline 1,4-dioxide - Drug resistant 4-methoxy-2,6-bis[hydroxy(methyl)amino]-1,3,5-triazine - Drug resistant 6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant indole-2,3-dione, 5-methyl-, 3-[(o-nitrophenyl)hydrazone] - Drug resistant 1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant 6-aryl alkyl fluoro quinolone derivative - Drug resistant 7-pentanoyltaxol - Drug resistant Annamycin Liposomal - Drug resistant antineoplastic-d655481 - Drug resistant geldanamycin dimethylglycinate - Drug resistant Indenoisoquinoline derivative - Drug resistant stereoisomer of nsc 675784-h - Drug resistant tgf.alpha.-pe40 - Drug resistant toxin .delta.53l - Drug resistant tp4ek - Drug resistant tp4ek-k6 - Drug resistant tunicamycin - Drug resistant viridomycin - Drug resistant (z) 3,3',4,5-tetramethoxystilbene - Drug sensitive 1,12-diaziridinyl-4,9-diazadodecane - Drug sensitive 1,2-benzo-8-(d,l-alanyl)-3-phenoxazone nitrate salt - Drug sensitive 1,4-naphthoquinone, 2-chloro-3-furfurylamino- - Drug sensitive 4(1h)-quinazolinone, 2,3-dihydro-2-(1-naphthyl)- (8ci) - Drug sensitive 4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive 4'-deoxy-13',17-dinitro-3',4'-epoxy-vincaleukoblastine - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug sensitive 6-(4-ethylphenyl)-2-(4-(methylsulfonyl)phenyl)-4,5-dihydropyridazin-3(2H)-one - Drug sensitive 7h-5,6-dithioleno[4,3-d]uracil - Drug sensitive 9-cis-retinol,palmitic acid ester - Drug sensitive 9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 2-phenyl- - Drug sensitive benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate - Drug sensitive benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive benzonitrile, 2-amino-3,5-dinitro- (9ci) - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive iodonium, (4-methoxyphenyl)(3-methylphenyl)-, bromide - Drug sensitive isoindolo[1,2-b]quinazoline, 10,12-dihydro-3-methyl-12-oxo- - Drug sensitive naphth[2,3-d]oxazol-9-one, 2-methyl-4-(phenylimino)- - Drug sensitive naphthalene-1,2-dione, 1,2-dihydro-4-[(3-pyridinyl)amino]- - Drug sensitive naphthalene-1,2-dione, 4-[(4-bromophenyl)amino]-, 1-oxime - Drug sensitive naphtho[1,2-c]quinolizinium, 13-methyl-, chloride - Drug sensitive naphtho[2,3-d]oxazole-4,9-dione, 2-(1,1-dimethylethyl)- - Drug sensitive phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) - Drug sensitive thiazolo[3,2-f]phenanthridinium, 3-phenyl- perchlorate - Drug sensitive thiourea, n-(1-ethylpropyl)-n'-[(2-thienyl)thioxomethyl]- - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 2-(4-hydroxy-benzylidene)-2-(2-pyridyl)acetonitrile - Drug sensitive 5-hydroxyamino camptothecin - Drug sensitive 6-nitro-1-indazolecarboxy-4'-chloro-2'-anisidide - Drug sensitive 9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive antineoplastic-615538 - Drug sensitive antineoplastic-d183258 - Drug sensitive b705009k098 - Drug sensitive chalmydocin - Drug sensitive chlorambucil-spermidine - Drug sensitive dichlorobisoxinatotitanium(iv) - Drug sensitive geldanamycin deriv - Drug sensitive tetra(isobutenyl)antimony bromide - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-502-5p	Oxaliplatine 6857599 Drug interaction    RC00005714 Topotecan 60700 Drug interaction    RC00005711 D-Glucose 5793 Drug interaction    RC00005708 Temozolomide 5394 Drug interaction    RC00005707 Eloxatine 5310940 Drug interaction    RC00005713 Paroxetine 43815 Drug interaction    RC00005710 5-Fluorouracil 3385 Drug interaction    RC00005706 Doxorubicin 31703 Drug interaction    RC00005709 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005705 Verapamil 2520 Drug interaction    RC00005704 Docetaxel 148124 Drug interaction    RC00005712 Leucovorin 135403648 Drug interaction    RC00005715 Mistletoe lectin-I - Drug interaction    RC00005717 1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00005716

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-502-5p
Interactor2: RBM27

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.