Detail Information

Basic Information:


  VIRBase ID:  

HHID00059722

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-519d-3p:           SLC16A9:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-519d-3p SLC16A9
miRBase
Accession/Entrez ID		 MIMAT0002853 220963
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C10orf36//MCT9

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-519d-3p
rs1031566931 chr19:53713420    T/A
rs116796400 chr19:53713416    A/G
rs1177367352 chr19:53713409    T/A
rs1362826944 chr19:53713419    G/T
rs1443130720 chr19:53713413    T/A
rs748935087 chr19:53713417    G/T
rs752635598 chr19:53713417    G/GTGTTACCCAAAGTGTTACCCAAACGTAACCCAA
rs754470034 chr19:53713415    T/TACCAA
rs754470034 chr19:53713415    T/TA
rs754629979 chr19:53713421    G/T
rs755601254 chr19:53713414    T/A
rs752048127 chr19:53713406    G/T
rs764695340 chr19:53713405    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SLC16A9
chr10:61453516(-) A-I      intronic
chr10:61453510(-) A-I      intronic
chr10:61453572(-) A-I      intronic
chr10:61453550(-) A-I      intronic
chr10:61453542(-) A-I      intronic
chr10:61447704(-) A-I      intronic
chr10:61447527(-) A-I      intronic
chr10:61454451(-) A-I      intronic
chr10:61454450(-) A-I      intronic
chr10:61454447(-) A-I      intronic
chr10:61447685(-) A-I      intronic
chr10:61454356(-) A-I      intronic
chr10:61446803(-) A-I      intronic
chr10:61458634(-) A-I      intronic
chr10:61463018(-) A-I      intronic
chr10:61458571(-) A-I      intronic
chr10:61446936(-) A-I      intronic
chr10:61447501(-) A-I      intronic
chr10:61447596(-) A-I      intronic
chr10:61447623(-) A-I      intronic
chr10:61447480(-) A-I      intronic
chr10:61446935(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLC16A9
chr10:61412019-61412020(-) m6A 3'UTR       24284625//27773535
chr10:61412056-61412057(-) m6A 3'UTR       24284625//24981863//27773535
chr10:61412063-61412064(-) m6A 3'UTR       24284625//24981863//27773535
chr10:61412164-61412165(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr10:61412299-61412300(-) m6A 3'UTR       24284625//27773535//22608085
chr10:61412386-61412387(-) Y 3'UTR       26075521
chr10:61412439-61412440(-) m6A 3'UTR       24981863//27773535
chr10:61412514-61412515(-) m6A 3'UTR       27773535
chr10:61412684-61412685(-) m6A CDS       22608085
chr10:61412690-61412691(-) m6A CDS       22608085
chr10:61413445-61413446(-) m6A CDS       24284625//22608085
chr10:61413463-61413464(-) m6A CDS       24284625//24981863//22608085
chr10:61413519-61413520(-) m6A CDS       24284625//24981863//27773535//22608085
chr10:61413712-61413713(-) m6A CDS       27773535//22608085
chr10:61413875-61413876(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr10:61413894-61413895(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr10:61413908-61413909(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr10:61413943-61413944(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr10:61413961-61413962(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr10:61414016-61414017(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr10:61414034-61414035(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085
chr10:61414039-61414040(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085
chr10:61414106-61414107(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr10:61414112-61414113(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr10:61414216-61414217(-) m6A CDS       24284625//22608085
chr10:61444043-61444044(-) m6A CDS//exon       27773536
chr10:61468412-61468413(-) m6A exon//intron       27773536
chr10:61468482-61468483(-) m6A exon//intron       27773536
chr10:61469418-61469419(-) m6A 5'UTR//intron       27773536
chr10:61469551-61469552(-) m6A 5'UTR//intron       25456834//24981863//27773536//22608085
chr10:61469563-61469564(-) m6A 5'UTR//intron       25456834//24981863//27773536//22608085
chr10:61469578-61469579(-) m6A 5'UTR//intron       25456834//24981863//27773536//22608085
chr10:61469605-61469606(-) m6A 5'UTR//intron       25456834//24981863//27773536//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-519d-3p
Exosome Serum     18589210
Exosome Human mast cell line (HMC-1)     24009880
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts     -
SLC16A9
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-519d-3p
Interactor2: SLC16A9

Evidence Support:


Weak-Evidence HITS-CLIP
Support Database ViRBase

References:


PMID 22473208 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Jijoye cells Interactor2 expression None
Description Our HITS-CLIP data yield 1185 human 3'UTRs targeted by members of the miR-17~92 cluster in Jijoye cells. Comparison to the 1664 3'UTRs targeted by EBV miRNAs reveals 740 shared genes (44% of EBV targets and 62% of miR-17~92 targets; Figure 6B and Supplementary Table 7). Thus, EBV miRNAs co-target a majority of miR-17~92 regulated mRNAs, which are assigned to a variety of pathways, most notably regulating transcription, apoptosis, and the cell cycle (Figure 6C). Similarly, other abundant immunologically relevant miRNAs, 142-3p and miR-155, co-target with EBV miRNAs a large fraction of their Ago-bound 3'UTRs, representing ~60% of the targets for each of these host miRNAs (Supplementary Figure 5).

Starting a new search, please wait ...