Detail Information

Basic Information:


  VIRBase ID:  

HHID00054089

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320a-3p:           FBXO33:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-320a-3p FBXO33
miRBase
Accession/Entrez ID		 MIMAT0000510 254170
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BMND12//c14_5247//Fbx33

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-320a-3p
rs1276783280 chr8:22244983    T/C
rs1304651256 chr8:22244976    C/A
rs1335522641 chr8:22244984    C/G
rs1342806696 chr8:22244985    A/T
rs1380599305 chr8:22244977    G/A
rs376090584 chr8:22244982    C/T
rs745462427 chr8:22244996    T/A
rs745462427 chr8:22244996    T/C
rs778232802 chr8:22244988    C/A
rs778232802 chr8:22244988    C/T
rs1029283088 chr8:22244995    T/C
rs1272164828 chr8:22244990    A/G
rs1295910991 chr8:22244991    G/C
rs1311220991 chr8:22244994    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FBXO33
chr14:39873700(-) A-I      intronic
chr14:39873699(-) A-I      intronic
chr14:39889702(-) A-I      intronic
chr14:39873695(-) A-I      intronic
chr14:39873687(-) A-I      intronic
chr14:39897043(-) A-I      intronic
chr14:39873639(-) A-I      intronic
chr14:39885041(-) A-I      intronic
chr14:39873711(-) A-I      intronic
chr14:39885122(-) A-I      intronic
chr14:39872068(-) A-I      intronic
chr14:39897146(-) A-I      intronic
chr14:39873705(-) A-I      intronic
chr14:39874109(-) A-I      intronic
chr14:39874276(-) A-I      intronic
chr14:39873759(-) A-I      intronic
chr14:39897502(-) A-I      intronic
chr14:39897534(-) A-I      intronic
chr14:39897578(-) A-I      intronic
chr14:39885135(-) A-I      intronic
chr14:39873703(-) A-I      intronic
chr14:39885035(-) A-I      intronic
chr14:39897628(-) A-I      intronic
chr14:39873702(-) A-I      intronic
chr14:39874324(-) A-I      intronic
chr14:39896900(-) A-I      intronic
chr14:39874185(-) A-I      intronic
chr14:39887396(-) A-I      intronic
chr14:39874265(-) A-I      intronic
chr14:39887416(-) A-I      intronic
chr14:39885150(-) A-I      intronic
chr14:39887457(-) A-I      intronic
chr14:39885022(-) A-I      intronic
chr14:39897547(-) A-I      intronic
chr14:39873802(-) A-I      intronic
chr14:39897068(-) A-I      intronic
chr14:39873216(-) A-I      intronic
chr14:39874118(-) A-I      intronic
chr14:39897036(-) A-I      intronic
chr14:39885144(-) A-I      intronic
chr14:39874314(-) A-I      intronic
chr14:39880397(-) A-I      intronic
chr14:39897142(-) A-I      intronic
chr14:39885044(-) A-I      intronic
chr14:39897636(-) A-I      intronic
chr14:39878058(-) A-I      intronic
chr14:39897095(-) A-I      intronic
chr14:39874096(-) A-I      intronic
chr14:39896926(-) A-I      intronic
chr14:39872051(-) A-I      intronic
chr14:39887446(-) A-I      intronic
chr14:39874244(-) A-I      intronic
chr14:39884498(-) A-I      intronic
chr14:39887447(-) A-I      intronic
chr14:39887540(-) A-I      intronic
chr14:39891449(-) A-I      intronic
chr14:39874240(-) A-I      intronic
chr14:39874108(-) A-I      intronic
chr14:39874146(-) A-I      intronic
chr14:39897506(-) A-I      intronic
chr14:39889848(-) A-I      intronic
chr14:39889743(-) A-I      intronic
chr14:39874243(-) A-I      intronic
chr14:39887892(-) A-I      intronic
chr14:39883944(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED FBXO33
chr14:39874244(-) A-G intron -    22484847
chr14:39874276(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FBXO33
chr14:39867607-39867608(-) m6A 3'UTR       24981863//22608085
chr14:39867658-39867659(-) m6A 3'UTR       22608085
chr14:39868726-39868727(-) m6A CDS       24284625//24981863//27773535//22608085
chr14:39868770-39868771(-) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//27371828//22608085
chr14:39868798-39868799(-) m6A 3'UTR//CDS       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr14:39868884-39868885(-) m6A 3'UTR//CDS       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr14:39870608-39870609(-) m6A CDS//intron       24284625//27773535//22608085
chr14:39870720-39870721(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr14:39870872-39870873(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:39870915-39870916(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:39871606-39871607(-) m6A CDS//intron       24284625
chr14:39871628-39871629(-) m6A CDS//intron       24284625
chr14:39871685-39871686(-) m6A CDS//intron       -
chr14:39871712-39871713(-) m6A CDS//intron       -
chr14:39900773-39900774(-) m6A CDS       -
chr14:39900876-39900877(-) m6A CDS       25456834//27371828//27773536//22608085
chr14:39900884-39900885(-) m6A CDS       25456834//27371828//27773536//22608085
chr14:39900926-39900927(-) m6A CDS       25456834//27371828//27773536//22608085
chr14:39901317-39901318(-) m6A CDS//intron       27773536
chr14:39901647-39901648(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-320a-3p
Apoptotic body Human umbilical vein endothelial cells     19996457
Cytoplasm Cardiomyocytes     31837603
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Human cervical cancer cell line (HeLa)     25760330
Exosome Pooled sera     27278097
Exosome Serum     18589210
Exosome Glioblastoma cells     19011622
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Ovarian follicular fluid     22116803
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome Serum     25135963
Exosome Human esophageal cancer cell line (EC9706)     25184951
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Cerebrospinal fluid     25420022
Exosome Blood|B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Colon tissue|Endothelial cells|Epithelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Seminal fluid|Tongue tissue     -
Extracellular vesicle HEK-293T cells     22849433
Microvesicle Glioblastoma cells     19011622
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Serum     24797360
Microvesicle Blood|Breast cell line|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion HEK-293 cells|HeLa cells     27396686
Mitochondrion HEK-293 cells|HeLa cells     27563705
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Cardiomyocytes     31837603
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Neural progenitor cells     21363885
FBXO33
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-320a-3p
Interactor2: FBXO33

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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