Detail Information

Basic Information:


  VIRBase ID:  

HHID00053887

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-195-5p:           TBC1D14:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-195-5p TBC1D14
miRBase
Accession/Entrez ID
MIMAT0000461 57533
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-195-5p
rs1346604530 chr17:7017676    T/C
rs1354352122 chr17:7017679    G/C
rs376953960 chr17:7017671    A/G
rs761226479 chr17:7017674    T/C
rs767045828 chr17:7017669    C/A
rs975705809 chr17:7017668    C/T
rs1230392050 chr17:7017682    C/T
rs1257736738 chr17:7017684    G/A
rs1311315368 chr17:7017686    T/C
rs1483556117 chr17:7017685    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TBC1D14
chr4:7020844(+) A-I      intronic
chr4:7019038(+) A-I      intronic
chr4:7018852(+) A-I      intronic
chr4:7018841(+) A-I      intronic
chr4:6997770(+) A-I      intronic
chr4:6997749(+) A-I      intronic
chr4:6997746(+) A-I      intronic
chr4:6997665(+) A-I      intronic
chr4:6997633(+) A-I      intronic
chr4:6991989(+) A-I      intronic
chr4:6982971(+) A-I      intronic
chr4:6977709(+) A-I      intronic
chr4:6977705(+) A-I      intronic
chr4:6977700(+) A-I      intronic
chr4:6977172(+) A-I      intronic
chr4:6977171(+) A-I      intronic
chr4:6977075(+) A-I      intronic
chr4:6977065(+) A-I      intronic
chr4:6977029(+) A-I      intronic
chr4:6977005(+) A-I      intronic
chr4:6976960(+) A-I      intronic
chr4:6976876(+) A-I      intronic
chr4:6976778(+) A-I      intronic
chr4:6976768(+) A-I      intronic
chr4:6976765(+) A-I      intronic
chr4:6976708(+) A-I      intronic
chr4:6960401(+) A-I      intronic
chr4:6960382(+) A-I      intronic
chr4:6960235(+) A-I      intronic
chr4:6959515(+) A-I      intronic
chr4:6959493(+) A-I      intronic
chr4:6954856(+) A-I      intronic
chr4:6951172(+) A-I      intronic
chr4:6950807(+) A-I      intronic
chr4:6950774(+) A-I      intronic
chr4:6950527(+) A-I      intronic
chr4:6950526(+) A-I      intronic
chr4:6950496(+) A-I      intronic
chr4:6950491(+) A-I      intronic
chr4:6948309(+) A-I      intronic
chr4:6948188(+) A-I      intronic
chr4:6936731(+) A-I      intronic
chr4:7013961(+) A-I      intronic
chr4:6936543(+) A-I      intronic
chr4:6935173(+) A-I      intronic
chr4:6935165(+) A-I      intronic
chr4:6933976(+) A-I      intronic
chr4:6933853(+) A-I      intronic
chr4:7013773(+) A-I      intronic
chr4:6932729(+) A-I      intronic
chr4:6932728(+) A-I      intronic
chr4:6932727(+) A-I      intronic
chr4:6932275(+) A-I      intronic
chr4:6915641(+) A-I      intronic
chr4:7013485(+) A-I      intronic
chr4:7013468(+) A-I      intronic
chr4:7013401(+) A-I      intronic
chr4:7010162(+) A-I      intronic
chr4:6999909(+) A-I      intronic
chr4:6999940(+) A-I      intronic
chr4:7031423(+) A-I      intronic
chr4:7031409(+) A-I      intronic
chr4:6999980(+) A-I      intronic
chr4:7031402(+) A-I      intronic
chr4:7031401(+) A-I      intronic
chr4:7031398(+) A-I      intronic
chr4:7031396(+) A-I      intronic
chr4:7031393(+) A-I      intronic
chr4:7031392(+) A-I      intronic
chr4:7031387(+) A-I      intronic
chr4:7031375(+) A-I      intronic
chr4:7028728(+) A-I      intronic
chr4:7028693(+) A-I      intronic
chr4:7028676(+) A-I      intronic
chr4:7013388(+) A-I      intronic
chr4:7000346(+) A-I      intronic
chr4:6932837(+) A-I      intronic
chr4:6932833(+) A-I      intronic
chr4:6932817(+) A-I      intronic
chr4:6932794(+) A-I      intronic
chr4:6932785(+) A-I      intronic
chr4:6999993(+) A-I      intronic
chr4:7000098(+) A-I      intronic
chr4:7000316(+) A-I      intronic
chr4:7031431(+) A-I      intronic
chr4:7030426(+) A-I      intronic
chr4:7030334(+) A-I      intronic
chr4:7030328(+) A-I      intronic
chr4:7030234(+) A-I      intronic
chr4:7030218(+) A-I      intronic
chr4:7028699(+) A-I      intronic
chr4:7028468(+) A-I      intronic
chr4:7028462(+) A-I      intronic
chr4:7028459(+) A-I      intronic
chr4:7028390(+) A-I      intronic
chr4:7028352(+) A-I      intronic
chr4:7000431(+) A-I      intronic
chr4:6983004(+) A-I      intronic
chr4:7000500(+) A-I      intronic
chr4:7010160(+) A-I      intronic
chr4:7010279(+) A-I      intronic
chr4:7013323(+) A-I      intronic
chr4:6936591(+) A-I      intronic
chr4:7023213(+) A-I      intronic
chr4:7022554(+) A-I      intronic
chr4:7022521(+) A-I      intronic
chr4:7020994(+) A-I      intronic
chr4:7020929(+) A-I      intronic
chr4:6932757(+) A-I      intronic
chr4:6977101(+) A-I      intronic
chr4:7031405(+) A-I      intronic
chr4:7013851(+) A-I      intronic
chr4:6948186(+) A-I      intronic
chr4:7013410(+) A-I      intronic
chr4:7000405(+) A-I      intronic
chr4:7023175(+) A-I      intronic
chr4:7000463(+) A-I      intronic
chr4:7022507(+) A-I      intronic
chr4:6948886(+) A-I      intronic
chr4:6977127(+) A-I      intronic
chr4:6996467(+) A-I      intronic
chr4:7030787(+) A-I      intronic
chr4:7027781(+) A-I      intronic
chr4:6959524(+) A-I      intronic
chr4:6933966(+) A-I      intronic
chr4:6932445(+) A-I      intronic
chr4:7028720(+) A-I      intronic
chr4:6981294(+) A-I      intronic
chr4:6948083(+) A-I      intronic
chr4:6960345(+) A-I      intronic
chr4:6959406(+) A-I      intronic
chr4:7013882(+) A-I      intronic
chr4:6971164(+) A-I      intronic
chr4:7020998(+) A-I      intronic
chr4:7028497(+) A-I      intronic
chr4:7031502(+) A-I      intronic
chr4:7031547(+) A-I      intronic
chr4:7030644(+) A-I      intronic
chr4:7031458(+) A-I      intronic
chr4:7028922(+) A-I      intronic
chr4:7030722(+) A-I      intronic
chr4:7013908(+) A-I      intronic
chr4:7000315(+) A-I      intronic
chr4:7013353(+) A-I      intronic
chr4:6932404(+) A-I      intronic
chr4:6948942(+) A-I      intronic
chr4:6932479(+) A-I      intronic
chr4:6996570(+) A-I      intronic
chr4:7018959(+) A-I      intronic
chr4:6936650(+) A-I      intronic
chr4:6981139(+) A-I      intronic
chr4:6948099(+) A-I      intronic
chr4:6981171(+) A-I      intronic
chr4:6999369(+) A-I      intronic
chr4:6948134(+) A-I      intronic
chr4:7030829(+) A-I      intronic
chr4:6932654(+) A-I      intronic
chr4:7018875(+) A-I      intronic
chr4:6932471(+) A-I      intronic
chr4:6992187(+) A-I      intronic
chr4:7031337(+) A-I      intronic
chr4:7031445(+) A-I      intronic
chr4:7000330(+) A-I      intronic
chr4:6935268(+) A-I      intronic
chr4:7013841(+) A-I      intronic
chr4:7020954(+) A-I      intronic
chr4:7028407(+) A-I      intronic
chr4:6948279(+) A-I      intronic
chr4:7030615(+) A-I      intronic
chr4:7000383(+) A-I      intronic
chr4:7031472(+) A-I      intronic
chr4:6981276(+) A-I      intronic
chr4:6962054(+) A-I      intronic
chr4:7028599(+) A-I      intronic
chr4:7024834(+) A-I      intronic
chr4:7031473(+) A-I      intronic
chr4:7013361(+) A-I      intronic
chr4:7028856(+) A-I      intronic
chr4:7022567(+) A-I      intronic
chr4:6922781(+) A-I      intronic
chr4:6935101(+) A-I      intronic
chr4:6932247(+) A-I      intronic
chr4:7028782(+) A-I      intronic
chr4:7020946(+) A-I      intronic
chr4:6991990(+) A-I      intronic
chr4:7018907(+) A-I      intronic
chr4:7013845(+) A-I      intronic
chr4:6954817(+) A-I      intronic
chr4:7028516(+) A-I      intronic
chr4:6936236(+) A-I      intronic
chr4:7023203(+) A-I      intronic
chr4:7028558(+) A-I      intronic
chr4:7028377(+) A-I      intronic
chr4:7027777(+) A-I      intronic
chr4:6997583(+) A-I      intronic
chr4:7020932(+) A-I      intronic
chr4:6936722(+) A-I      intronic
chr4:6981287(+) A-I      intronic
chr4:6950485(+) A-I      intronic
chr4:7018867(+) A-I      intronic
chr4:6932900(+) A-I      intronic
chr4:6996536(+) A-I      intronic
chr4:7000366(+) A-I      intronic
chr4:7024754(+) A-I      intronic
chr4:6948287(+) A-I      intronic
chr4:6999967(+) A-I      intronic
chr4:7018871(+) A-I      intronic
chr4:6936619(+) A-I      intronic
chr4:7024931(+) A-I      intronic
chr4:7031376(+) A-I      intronic
chr4:6935216(+) A-I      intronic
chr4:7013384(+) A-I      intronic
chr4:7030595(+) A-I      intronic
chr4:7028533(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TBC1D14
chr4:6946203(+) A-I intron -    15342557
chr4:6946691(+) A-I intron -    15342557
chr4:6947212(+) A-I intron -    15342557
chr4:6947256(+) A-I intron -    15342557
chr4:6947261(+) A-I intron -    15342557
chr4:6947280(+) A-I intron -    15342557
chr4:6947311(+) A-I intron -    15342557
chr4:6947314(+) A-I intron -    15342557
chr4:6947315(+) A-I intron -    15342557
chr4:6947316(+) A-I intron -    15342557
chr4:6947356(+) A-I intron -    15342557
chr4:6947388(+) A-I intron -    15342557
chr4:6947397(+) A-I intron -    15342557
chr4:6947441(+) G-A intron -    21725310
chr4:6932247(+) A-G intron -    22484847
chr4:6932404(+) A-G intron -    22484847
chr4:6932405(+) A-G intron -    22484847
chr4:6932479(+) A-G intron -    22484847
chr4:6932654(+) A-G intron -    22484847
chr4:6932767(+) A-G intron -    22484847
chr4:6948083(+) A-G intron -    22484847
chr4:6948134(+) A-G intron -    22484847
chr4:6948287(+) A-G intron -    22484847
chr4:6950485(+) A-G intron -    22484847
chr4:6953124(+) T-C intron -    22484847
chr4:6954806(+) A-G intron -    22484847
chr4:6954809(+) A-G intron -    22484847
chr4:6954817(+) A-G intron -    22484847
chr4:6954852(+) A-G intron -    22484847
chr4:6960345(+) A-G intron -    22484847
chr4:6966899(+) T-G intron -    22484847
chr4:6976838(+) A-G intron -    22484847
chr4:6976909(+) A-G intron -    22484847
chr4:6999908(+) A-G intron -    22484847
chr4:6999967(+) A-G intron -    22484847
chr4:7000330(+) A-G intron -    22484847
chr4:7000366(+) A-G intron -    22484847
chr4:7000378(+) A-G intron -    22484847
chr4:7000405(+) A-G intron -    22484847
chr4:7000463(+) A-G intron -    22484847
chr4:7013340(+) A-G intron -    22484847
chr4:7013353(+) A-G intron -    22484847
chr4:7013361(+) A-G intron -    22484847
chr4:7013410(+) A-G intron -    22484847
chr4:7013465(+) A-G intron -    22484847
chr4:7013882(+) A-G intron -    22484847
chr4:7013908(+) A-G intron -    22484847
chr4:7018867(+) A-G intron -    22484847
chr4:7018907(+) A-G intron -    22484847
chr4:7018959(+) A-G intron -    22484847
chr4:7020932(+) A-G intron -    22484847
chr4:7020946(+) A-G intron -    22484847
chr4:7020954(+) A-G intron -    22484847
chr4:7020998(+) A-G intron -    22484847
chr4:7022507(+) A-G intron -    22484847
chr4:7022553(+) A-G intron -    22484847
chr4:7022557(+) A-G intron -    22484847
chr4:7023175(+) A-G intron -    22484847
chr4:7023203(+) A-G intron -    22484847
chr4:7028362(+) A-G intron -    22484847
chr4:7028377(+) A-G intron -    22484847
chr4:7028442(+) A-G intron -    22484847
chr4:7028465(+) A-G intron -    22484847
chr4:7028856(+) A-G intron -    22484847
chr4:7028922(+) A-G intron -    22484847
chr4:7031405(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TBC1D14
chr4:6925110-6925111(+) m6A 5'UTR       -
chr4:6925130-6925131(+) m6A CDS       24284625
chr4:6925189-6925190(+) m6A CDS       24284625//22608085
chr4:6925201-6925202(+) m6A CDS       24284625//22608085
chr4:6925268-6925269(+) m6A CDS       24284625//24981863//22608085
chr4:6925285-6925286(+) m6A CDS       24284625//24981863//22608085
chr4:6925309-6925310(+) m6A CDS       24284625//24981863//22608085
chr4:6925339-6925340(+) m6A CDS       24284625//24981863//22608085
chr4:6925478-6925479(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr4:6925512-6925513(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr4:6925605-6925606(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr4:6925642-6925643(+) m6A CDS       24284625//25456834//24981863//26404942//22575960//22608085
chr4:6925651-6925652(+) m6A CDS       24284625//25456834//24981863//26404942//22575960//22608085
chr4:6925746-6925747(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085
chr4:6925768-6925769(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085
chr4:6956025-6956026(+) m6A 5'UTR//intron       24284625//24981863//22608085
chr4:6956061-6956062(+) m6A CDS//intron       24284625//24981863//22608085
chr4:6969032-6969033(+) m6A CDS       24284625//24981863
chr4:6969048-6969049(+) m6A CDS       24284625//24981863
chr4:6969069-6969070(+) m6A CDS       24284625//24981863
chr4:6995920-6995921(+) m6A 5'UTR//CDS       24209618//24981863
chr4:6995933-6995934(+) m6A 5'UTR//CDS       24209618//24981863
chr4:6995987-6995988(+) m6A 5'UTR//CDS//exon       24209618//24981863
chr4:6996019-6996020(+) m6A 5'UTR//CDS//exon       24981863
chr4:6998066-6998067(+) m6A 5'UTR//CDS//exon       24981863
chr4:6998093-6998094(+) m6A 5'UTR//CDS//exon       24981863
chr4:7006641-7006642(+) Gm CDS       -
chr4:7026855-7026856(+) m6A CDS       24284625//25456834
chr4:7026873-7026874(+) m6A CDS       24284625//25456834
chr4:7026915-7026916(+) m6A CDS       24284625//25456834//22575960
chr4:7026972-7026973(+) m6A CDS       24284625//25456834//22575960//22608085
chr4:7032075-7032076(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr4:7032186-7032187(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr4:7032211-7032212(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr4:7032232-7032233(+) Y 3'UTR       26075521
chr4:7032257-7032258(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr4:7032262-7032263(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr4:7032274-7032275(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr4:7032290-7032291(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr4:7032338-7032339(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr4:7032503-7032504(+) m6A 3'UTR       24284625//24209618
chr4:7033001-7033002(+) m6A 3'UTR       24284625
chr4:7033074-7033075(+) m6A 3'UTR       24284625
chr4:7033181-7033182(+) m6A 3'UTR       24284625//22608085
chr4:7033207-7033208(+) m6A 3'UTR       24284625//22608085
chr4:7033290-7033291(+) m6A 3'UTR       24284625//22608085
chr4:7033303-7033304(+) m6A 3'UTR       24284625//22608085
chr4:7033332-7033333(+) m6A 3'UTR       24284625//22608085
chr4:7033432-7033433(+) m6A 3'UTR       24284625
chr4:7033649-7033650(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr4:7033763-7033764(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr4:7033818-7033819(+) m6A 3'UTR       24284625//24209618//24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-195-5p
Exosome Serum     18589210
Exosome Primary dendritic cells|T cell line (J77)     21505438
Exosome Breast milk     22211110
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
TBC1D14
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID
Function
ncDR hsa-miR-195-5p
Succinimide, 3-chloro-N-(p-methoxyphenyl)- 99724 Drug resistant
(3R,10S,13S,16S,19R)-16-[(2S)-Butan-2-yl]-10,11,14-trimethyl-3-(2-methylpropyl)-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone 90471303 Drug resistant
Acridine Yellow G 8672 Drug resistant
2-Amino-3H-phenoxazin-3-one 72725 Drug sensitive
1-(2-Pyridylazo)-2-naphthol 6825 Drug resistant
Deferoxamine hydrochloride 62880 Drug resistant
21-[2-(N,3,5(10),17(20)-Tetraen-3-ol citrate salt 54612678 Drug sensitive
(10R,13R,16R,19S)-16-Butan-2-yl-3-(3-chloro-2-hydroxypropyl)-10,11,14-trimethyl-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone 5459202 Drug resistant
2-Methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol 5386397 Drug sensitive
1-Piperidineethanol, alpha-[p-(p-chlorostyryl)phenyl]- 5351150 Drug resistant
Amonafide 50515 Drug resistant
Justicidin B 442882 Drug resistant
Entinostat 4261 Drug resistant
5-Benzyl-9-hydroxy-5H-indeno[1,2-b]indol-10-one 406582 Drug sensitive
Massoia lactone 39914 Drug resistant
1H-Indole, 5-bromo-3-[2-(2-pyridinyl)-4-thiazolyl]- 397551 Drug resistant
L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug resistant
Stereoisomer of NSC 674066-O 384359 Drug resistant
2-Amino-5,8-dihydroxy-1,4-naphthoquinone 377209 Drug resistant
Miltefosine 3599 Drug resistant
2-Chloro-3-(dodecylsulfanyl)-5,6-dimethoxycyclohexa-2,5-diene-1,4-dione 312122 Drug sensitive
L-Cysteine, S-[(4-chlorophenyl)diphenylmethyl]- 275977 Drug sensitive
Antineoplastic-92909 261046 Drug sensitive
Spongiaquinone 23424796 Drug sensitive
8-Hydroxyquinoline 1923 Drug resistant
Verrucarin A 9,10-epoxide 181390 Drug resistant
Aklavin 149755 Drug resistant
Perifosine 148177 Drug resistant
Edelfosine 1392 Drug resistant
Emofolin sodium 135475347 Drug resistant
1-Phenazinecarboxylic acid, 6-formyl-4,7,9-trihydroxy-, methyl ester 135457300 Drug sensitive
Octadecylphosphocholine 125219 Drug resistant
Pararosaniline hydrochloride 11292 Drug sensitive
Erigerol 101318126 Drug resistant
Cinnoline, 4-nitro-, 1-oxide 100397 Drug resistant
1,8-octanediamine, n,n'-di-9-acridinyl- (9ci) - Drug resistant
ethanol, 2-[4-(2,2':6',2-terpyridin-4'-yl)phenoxy]- - Drug resistant
tellurium, trichloro[1,2-hexanedioato(2-)-o,o']-, ammonium - Drug resistant
1-o-benzoylcastanospermine - Drug resistant
methyl (e)-4-methyl-6-(5-bromo-2-hydroxyphenyl)-4-hexenoate - Drug resistant
xenorhabdin 1 - Drug resistant
(2r,3r)-(+)-methyl 3-phenyloxirane-carboxylate - Drug sensitive
2,4-diethoxyestra-1,3,5(10)trien-3,17.beta.-diol - Drug sensitive
3,4-diphenylisoxazolo[3,4-d]pyridazin-7(6h)-one - Drug sensitive
6-Chloro-5-[2-(piperazin-1-yl)ethyl]-1,3-dihydro-2H-indol-2-one - Drug sensitive
6-aryl alkyl fluoro quinolone derivative - Drug sensitive
crotoxin cd - Drug sensitive
Resource Symbol Drug Name PubChem
ID
Function Link  
RNAInter hsa-miR-195-5p
Palmitic acid 985 Drug interaction    RC00003301
Curcumin 969516 Drug interaction    RC00003314
Benzothiazole 7222 Drug interaction    RC00003308
Gemcitabine 60750 Drug interaction    RC00003311
D-Glucose 5793 Drug interaction    RC00003307
Temozolomide 5394 Drug interaction    RC00003306
Eloxatine 5310940 Drug interaction    RC00003315
Imatinib 5291 Drug interaction    RC00003305
Diethylstilbestrol 448537 Drug interaction    RC00003313
Paclitaxel 36314 Drug interaction    RC00003310
5-Fluorouracil 3385 Drug interaction    RC00003304
Doxorubicin 31703 Drug interaction    RC00003309
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00003303
Celecoxib 2662 Drug interaction    RC00003302
Docetaxel 148124 Drug interaction    RC00003312
platinum-based doublet chemotherapy - Drug interaction    RC00003316
1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00003317
Aidi injection - Drug interaction    RC00003318
Trastuzumab - Drug interaction    RC00003320
Glucocorticoid - Drug interaction    RC00003319
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-195-5p

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-195-5p
Interactor2: TBC1D14

Evidence Support:


Weak-Evidence HITS-CLIP
Support Database ViRBase

References:


PMID 22473208 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Jijoye cells Interactor2 expression None
Description Our HITS-CLIP data yield 1185 human 3'UTRs targeted by members of the miR-17~92 cluster in Jijoye cells. Comparison to the 1664 3'UTRs targeted by EBV miRNAs reveals 740 shared genes (44% of EBV targets and 62% of miR-17~92 targets; Figure 6B and Supplementary Table 7). Thus, EBV miRNAs co-target a majority of miR-17~92 regulated mRNAs, which are assigned to a variety of pathways, most notably regulating transcription, apoptosis, and the cell cycle (Figure 6C). Similarly, other abundant immunologically relevant miRNAs, 142-3p and miR-155, co-target with EBV miRNAs a large fraction of their Ago-bound 3'UTRs, representing ~60% of the targets for each of these host miRNAs (Supplementary Figure 5).

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