Detail Information

Basic Information:


  VIRBase ID:  

HHID00053474

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           HECA:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p HECA
miRBase
Accession/Entrez ID		 MIMAT0000458 51696
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - dJ225E12.1//HDC//HDCL//HHDC

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR HECA
chr6:139462990(+) A-I      intronic
chr6:139462914(+) A-I      intronic
chr6:139461947(+) A-I      intronic
chr6:139479236(+) A-I      intronic
chr6:139477556(+) A-I      intronic
chr6:139477544(+) A-I      intronic
chr6:139477537(+) A-I      intronic
chr6:139463965(+) A-I      intronic
chr6:139468587(+) A-I      intronic
chr6:139464887(+) A-I      intronic
chr6:139477479(+) A-I      intronic
chr6:139464822(+) A-I      intronic
chr6:139463806(+) A-I      intronic
chr6:139464877(+) A-I      intronic
chr6:139468563(+) A-I      intronic
chr6:139474653(+) A-I      intronic
chr6:139477581(+) A-I      intronic
chr6:139468507(+) A-I      intronic
chr6:139468521(+) A-I      intronic
chr6:139464812(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED HECA
chr6:139463270(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HECA
chr6:139456412-139456413(+) m6A 5'UTR       24209618
chr6:139456549-139456550(+) m6A CDS       24209618//27371828
chr6:139456570-139456571(+) m6A CDS       24209618//27371828
chr6:139487468-139487469(+) m6A CDS       24209618
chr6:139487633-139487634(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139487641-139487642(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139487711-139487712(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085
chr6:139487717-139487718(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085
chr6:139487777-139487778(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085
chr6:139487885-139487886(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085
chr6:139487894-139487895(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085
chr6:139488153-139488154(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488191-139488192(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488201-139488202(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488233-139488234(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488284-139488285(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488338-139488339(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488375-139488376(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr6:139488397-139488398(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr6:139488420-139488421(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr6:139495525-139495526(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr6:139495554-139495555(+) m6A CDS       -
chr6:139500156-139500157(+) m6A 3'UTR       26404942
chr6:139500211-139500212(+) m6A 3'UTR       26404942
chr6:139500249-139500250(+) m6A 3'UTR       26404942
chr6:139500265-139500266(+) m6A 3'UTR       26404942
chr6:139500591-139500592(+) m6A 3'UTR       26404942
chr6:139500641-139500642(+) m6A 3'UTR       26404942
chr6:139501402-139501403(+) m6A 3'UTR       26404942
chr6:139501410-139501411(+) m6A 3'UTR       26404942
chr6:139501423-139501424(+) m6A 3'UTR       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
HECA
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: HECA

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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