Detail Information

Basic Information:


  VIRBase ID:  

HHID00053458

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           CRIPT:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p CRIPT
miRBase
Accession/Entrez ID		 MIMAT0000458 9419
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HSPC139//SSMDF

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CRIPT
chr2:46852400(+) A-I      3'UTR
chr2:46852390(+) A-I      3'UTR
chr2:46852393(+) A-I      3'UTR
chr2:46852384(+) A-I      3'UTR
chr2:46849302(+) A-I      intronic
chr2:46847425(+) A-I      intronic
chr2:46847436(+) A-I      intronic
chr2:46852377(+) A-I      3'UTR
chr2:46852420(+) A-I      3'UTR
chr2:46852340(+) A-I      3'UTR
chr2:46852336(+) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CRIPT
chr2:46844405-46844406(+) m6A 5'UTR//intron       24209618//24981863
chr2:46845921-46845922(+) m6A CDS//exon       24209618//24981863
chr2:46852113-46852114(+) m6A 3'UTR//exon       24981863
chr2:46852118-46852119(+) m6A 3'UTR//exon       24981863
chr2:46852177-46852178(+) m6A 3'UTR//exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
CRIPT
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: CRIPT

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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