Detail Information

Basic Information:


  VIRBase ID:  

HHID00053449

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           OAS3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p OAS3
miRBase
Accession/Entrez ID		 MIMAT0000458 4940
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - p100//p100OAS

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR OAS3
chr12:113380327(+) A-I      intronic
chr12:113380328(+) A-I      intronic
chr12:113381000(+) A-I      intronic
chr12:113380333(+) A-I      intronic
chr12:113380365(+) A-I      intronic
chr12:113380929(+) A-I      intronic
chr12:113380417(+) A-I      intronic
chr12:113380762(+) A-I      intronic
chr12:113380369(+) A-I      intronic
chr12:113380518(+) A-I      intronic
chr12:113380889(+) A-I      intronic
chr12:113380412(+) A-I      intronic
chr12:113380366(+) A-I      intronic
chr12:113377315(+) A-I      intronic
chr12:113379077(+) A-I      intronic
chr12:113381619(+) A-I      intronic
chr12:113377205(+) A-I      intronic
chr12:113380334(+) A-I      intronic
chr12:113381758(+) A-I      intronic
chr12:113380349(+) A-I      intronic
chr12:113377360(+) A-I      intronic
chr12:113378870(+) A-I      intronic
chr12:113380844(+) A-I      intronic
chr12:113380969(+) A-I      intronic
chr12:113380949(+) A-I      intronic
chr12:113380501(+) A-I      intronic
chr12:113380823(+) A-I      intronic
chr12:113386202(+) A-I      intronic
chr12:113380330(+) A-I      intronic
chr12:113381745(+) A-I      intronic
chr12:113381658(+) A-I      intronic
chr12:113381772(+) A-I      intronic
chr12:113380238(+) A-I      intronic
chr12:113380841(+) A-I      intronic
chr12:113380858(+) A-I      intronic
chr12:113381707(+) A-I      intronic
chr12:113380326(+) A-I      intronic
chr12:113380761(+) A-I      intronic
chr12:113380921(+) A-I      intronic
chr12:113377422(+) A-I      intronic
chr12:113380937(+) A-I      intronic
chr12:113381008(+) A-I      intronic
chr12:113378991(+) A-I      intronic
chr12:113377402(+) A-I      intronic
chr12:113380368(+) A-I      intronic
chr12:113380892(+) A-I      intronic
chr12:113380388(+) A-I      intronic
chr12:113381133(+) A-I      intronic
chr12:113380385(+) A-I      intronic
chr12:113380840(+) A-I      intronic
chr12:113381014(+) A-I      intronic
chr12:113380845(+) A-I      intronic
chr12:113381379(+) A-I      intronic
chr12:113381378(+) A-I      intronic
chr12:113381389(+) A-I      intronic
chr12:113380350(+) A-I      intronic
chr12:113406188(+) A-I      intronic
chr12:113408811(+) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED OAS3
chr12:113377360(+) A-G intron -    22484847
chr12:113377402(+) A-G intron -    22484847
chr12:113380330(+) A-G intron -    22484847
chr12:113380949(+) A-G intron -    22484847
chr12:113377315(+) A-G intron -    22484847
chr12:113378870(+) A-G intron -    22484847
chr12:113379077(+) A-G intron -    22484847
chr12:113380238(+) A-G intron -    22484847
chr12:113380762(+) A-G intron -    22484847
chr12:113380823(+) A-G intron -    22484847
chr12:113380840(+) A-G intron -    22484847
chr12:113380841(+) A-G intron -    22484847
chr12:113380845(+) A-G intron -    22484847
chr12:113380858(+) A-G intron -    22484847
chr12:113380921(+) A-G intron -    22484847
chr12:113380928(+) T-C intron -    22484847
chr12:113380937(+) A-G intron -    22484847
chr12:113380948(+) T-C intron -    22484847
chr12:113380969(+) A-G intron -    22484847
chr12:113381619(+) A-G intron -    22484847
chr12:113381707(+) A-G intron -    22484847
chr12:113382876(+) A-G intron -    22484847
chr12:113386202(+) A-G intron -    22484847
chr12:113406562(+) C-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase OAS3
chr12:113376172-113376173(+) m6A 5'UTR       24981863
chr12:113376178-113376179(+) m6A 5'UTR       24981863
chr12:113376215-113376216(+) m6A 5'UTR       24981863
chr12:113376222-113376223(+) m6A 5'UTR       24981863
chr12:113376229-113376230(+) m6A 5'UTR       24981863
chr12:113376275-113376276(+) m6A 5'UTR       24981863
chr12:113376339-113376340(+) m6A CDS       24981863
chr12:113376369-113376370(+) m6A CDS//exon       24981863
chr12:113376503-113376504(+) m6A CDS//exon       -
chr12:113379424-113379425(+) m6A CDS//intron       -
chr12:113379462-113379463(+) m6A CDS//intron       -
chr12:113379528-113379529(+) m6A CDS//intron       24209618//25456834//24981863//22575960
chr12:113379547-113379548(+) m6A CDS//intron       24209618//25456834//24981863//22575960
chr12:113379615-113379616(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960
chr12:113379672-113379673(+) m6A CDS//intron       24284625//24209618//25456834//24981863
chr12:113379707-113379708(+) m6A CDS//intron       24209618//25456834//24981863
chr12:113379717-113379718(+) m6A CDS//intron       24209618//25456834//24981863
chr12:113379796-113379797(+) m6A 3'UTR//intron       24209618//24981863
chr12:113379801-113379802(+) m6A 3'UTR//intron       24209618//24981863
chr12:113379810-113379811(+) m6A 3'UTR//intron       24209618//24981863
chr12:113379821-113379822(+) m6A 3'UTR//intron       24209618//24981863
chr12:113379835-113379836(+) m6A 3'UTR//intron       24209618//24981863
chr12:113379977-113379978(+) m6A 3'UTR//intron       24209618//24981863
chr12:113388576-113388577(+) m6A CDS//exon       24981863
chr12:113388585-113388586(+) m6A CDS//exon       24981863
chr12:113405793-113405794(+) m6A CDS       24981863
chr12:113405831-113405832(+) m6A CDS       24284625//24981863
chr12:113405911-113405912(+) m6A CDS       24284625
chr12:113405933-113405934(+) m6A CDS       24284625
chr12:113405938-113405939(+) m6A CDS       24284625
chr12:113405948-113405949(+) m6A CDS       24284625
chr12:113409095-113409096(+) m6A 3'UTR       24981863
chr12:113409100-113409101(+) m6A 3'UTR       24981863
chr12:113410501-113410502(+) m6A 3'UTR       24981863
chr12:113410635-113410636(+) m6A 3'UTR       24981863
chr12:113410647-113410648(+) m6A 3'UTR       24981863
chr12:113410841-113410842(+) m6A 3'UTR       27773535
chr12:113410905-113410906(+) m6A 3'UTR       24981863//27773535
chr12:113410929-113410930(+) m6A 3'UTR       24981863//27773535
chr12:113410937-113410938(+) m6A 3'UTR       24981863//27773535
chr12:113410993-113410994(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
OAS3
Exosome Blood     -
Nucleus Colon cancer cells     24393600
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: OAS3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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