Basic Information:

  VIRBase ID:  

HHID00053249

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-185-5p:  MIMAT0000455          ZSWIM6:  NM_020928     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-185-5p	ZSWIM6
miRBase Accession/Entrez ID	MIMAT0000455	57688
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	AFND//NEDMAGA

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-185-5p	rs1249170072 chr22:20033164    G/A rs770235403 chr22:20033168    T/C rs775856637 chr22:20033173    G/A rs1398989482 chr22:20033154    G/A rs761385932 chr22:20033159    GAA/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZSWIM6	chr5:60635069(+) A-I      intronic chr5:60674643(+) A-I      intronic chr5:60674522(+) A-I      intronic chr5:60674460(+) A-I      intronic chr5:60674439(+) A-I      intronic chr5:60673456(+) A-I      intronic chr5:60663869(+) A-I      intronic chr5:60663734(+) A-I      intronic chr5:60663714(+) A-I      intronic chr5:60663692(+) A-I      intronic chr5:60679997(+) A-I      intronic chr5:60663686(+) A-I      intronic chr5:60663674(+) A-I      intronic chr5:60663355(+) A-I      intronic chr5:60663157(+) A-I      intronic chr5:60663107(+) A-I      intronic chr5:60662755(+) A-I      intronic chr5:60635073(+) A-I      intronic chr5:60674856(+) A-I      intronic chr5:60674842(+) A-I      intronic chr5:60635072(+) A-I      intronic chr5:60680002(+) A-I      intronic chr5:60683462(+) A-I      intronic chr5:60683909(+) A-I      intronic chr5:60683971(+) A-I      intronic chr5:60641871(+) A-I      intronic chr5:60641872(+) A-I      intronic chr5:60641977(+) A-I      intronic chr5:60659903(+) A-I      intronic chr5:60659975(+) A-I      intronic chr5:60689450(+) A-I      intronic chr5:60689458(+) A-I      intronic chr5:60717024(+) A-I      intronic chr5:60719048(+) A-I      intronic chr5:60719052(+) A-I      intronic chr5:60724304(+) A-I      intronic chr5:60724418(+) A-I      intronic chr5:60724472(+) A-I      intronic chr5:60745254(+) A-I      intronic chr5:60674797(+) A-I      intronic chr5:60801775(+) A-I      intronic chr5:60661931(+) A-I      intronic chr5:60661997(+) A-I      intronic chr5:60662615(+) A-I      intronic chr5:60662706(+) A-I      intronic chr5:60662715(+) A-I      intronic chr5:60683556(+) A-I      intronic chr5:60801780(+) A-I      intronic chr5:60825024(+) A-I      intronic chr5:60825025(+) A-I      intronic chr5:60632503(+) A-I      intronic chr5:60754611(+) A-I      intronic chr5:60754620(+) A-I      intronic chr5:60754630(+) A-I      intronic chr5:60754644(+) A-I      intronic chr5:60662725(+) A-I      intronic chr5:60824544(+) A-I      intronic chr5:60676003(+) A-I      intronic chr5:60663214(+) A-I      intronic chr5:60663183(+) A-I      intronic chr5:60683591(+) A-I      intronic chr5:60824946(+) A-I      intronic chr5:60824954(+) A-I      intronic chr5:60724433(+) A-I      intronic chr5:60824532(+) A-I      intronic chr5:60745257(+) A-I      intronic chr5:60825017(+) A-I      intronic chr5:60632461(+) A-I      intronic chr5:60632462(+) A-I      intronic chr5:60632479(+) A-I      intronic chr5:60679813(+) A-I      intronic chr5:60679554(+) A-I      intronic chr5:60632488(+) A-I      intronic chr5:60632491(+) A-I      intronic chr5:60802228(+) A-I      intronic chr5:60802226(+) A-I      intronic chr5:60802333(+) A-I      intronic chr5:60679540(+) A-I      intronic chr5:60679539(+) A-I      intronic chr5:60678602(+) A-I      intronic chr5:60678582(+) A-I      intronic chr5:60678538(+) A-I      intronic chr5:60678534(+) A-I      intronic chr5:60678521(+) A-I      intronic chr5:60678511(+) A-I      intronic chr5:60678470(+) A-I      intronic chr5:60678468(+) A-I      intronic chr5:60678430(+) A-I      intronic chr5:60678421(+) A-I      intronic chr5:60676969(+) A-I      intronic chr5:60676959(+) A-I      intronic chr5:60676933(+) A-I      intronic chr5:60676900(+) A-I      intronic chr5:60675014(+) A-I      intronic chr5:60802289(+) A-I      intronic chr5:60674929(+) A-I      intronic chr5:60802283(+) A-I      intronic chr5:60641836(+) A-I      intronic chr5:60635086(+) A-I      intronic chr5:60714151(+) A-I      intronic chr5:60674861(+) A-I      intronic chr5:60673424(+) A-I      intronic chr5:60688504(+) A-I      intronic chr5:60673389(+) A-I      intronic chr5:60661085(+) A-I      intronic chr5:60679576(+) A-I      intronic chr5:60674887(+) A-I      intronic chr5:60727069(+) A-I      intronic chr5:60688579(+) A-I      intronic chr5:60674941(+) A-I      intronic chr5:60683558(+) A-I      intronic chr5:60676655(+) A-I      intronic chr5:60824494(+) A-I      intronic chr5:60753571(+) A-I      intronic chr5:60674858(+) A-I      intronic chr5:60679648(+) A-I      intronic chr5:60720822(+) A-I      intronic chr5:60724207(+) A-I      intronic chr5:60726943(+) A-I      intronic chr5:60679503(+) A-I      intronic chr5:60824515(+) A-I      intronic chr5:60719144(+) A-I      intronic chr5:60678571(+) A-I      intronic chr5:60678517(+) A-I      intronic chr5:60712706(+) A-I      intronic chr5:60688496(+) A-I      intronic chr5:60662635(+) A-I      intronic chr5:60692238(+) A-I      intronic chr5:60802155(+) A-I      intronic chr5:60659972(+) A-I      intronic chr5:60729576(+) A-I      intronic chr5:60685262(+) A-I      intronic chr5:60679529(+) A-I      intronic chr5:60724240(+) A-I      intronic chr5:60720744(+) A-I      intronic chr5:60662681(+) A-I      intronic chr5:60679382(+) A-I      intronic chr5:60675967(+) A-I      intronic chr5:60674949(+) A-I      intronic chr5:60674743(+) A-I      intronic chr5:60674897(+) A-I      intronic chr5:60824991(+) A-I      intronic chr5:60688539(+) A-I      intronic chr5:60720823(+) A-I      intronic chr5:60824955(+) A-I      intronic chr5:60678465(+) A-I      intronic chr5:60683927(+) A-I      intronic chr5:60679389(+) A-I      intronic chr5:60714195(+) A-I      intronic chr5:60674585(+) A-I      intronic chr5:60824941(+) A-I      intronic chr5:60712712(+) A-I      intronic chr5:60678455(+) A-I      intronic chr5:60720755(+) A-I      intronic chr5:60662677(+) A-I      intronic chr5:60662613(+) A-I      intronic chr5:60632407(+) A-I      intronic chr5:60719115(+) A-I      intronic chr5:60689506(+) A-I      intronic chr5:60679654(+) A-I      intronic chr5:60673390(+) A-I      intronic chr5:60679814(+) A-I      intronic chr5:60674765(+) A-I      intronic chr5:60731774(+) A-I      intronic chr5:60674592(+) A-I      intronic chr5:60662000(+) A-I      intronic chr5:60716886(+) A-I      intronic chr5:60719088(+) A-I      intronic chr5:60802156(+) A-I      intronic chr5:60754558(+) A-I      intronic chr5:60637887(+) A-I      intronic chr5:60674509(+) A-I      intronic chr5:60688540(+) A-I      intronic chr5:60674901(+) A-I      intronic chr5:60674524(+) A-I      intronic chr5:60661883(+) A-I      intronic chr5:60824921(+) A-I      intronic chr5:60716982(+) A-I      intronic chr5:60683578(+) A-I      intronic chr5:60674940(+) A-I      intronic chr5:60720658(+) A-I      intronic chr5:60661763(+) A-I      intronic chr5:60712707(+) A-I      intronic chr5:60632852(+) A-I      intronic chr5:60674463(+) A-I      intronic chr5:60689515(+) A-I      intronic chr5:60714194(+) A-I      intronic chr5:60676960(+) A-I      intronic chr5:60659923(+) A-I      intronic chr5:60824983(+) A-I      intronic chr5:60674567(+) A-I      intronic chr5:60662609(+) A-I      intronic chr5:60678552(+) A-I      intronic chr5:60688966(+) A-I      intronic chr5:60683573(+) A-I      intronic chr5:60661922(+) A-I      intronic chr5:60754594(+) A-I      intronic chr5:60661762(+) A-I      intronic chr5:60663349(+) A-I      intronic chr5:60683990(+) A-I      intronic chr5:60679636(+) A-I      intronic chr5:60662704(+) A-I      intronic chr5:60661896(+) A-I      intronic chr5:60679432(+) A-I      intronic chr5:60663771(+) A-I      intronic chr5:60720684(+) A-I      intronic chr5:60660011(+) A-I      intronic chr5:60683262(+) A-I      intronic chr5:60683572(+) A-I      intronic chr5:60662610(+) A-I      intronic chr5:60683994(+) A-I      intronic chr5:60632844(+) A-I      intronic chr5:60754495(+) A-I      intronic chr5:60674885(+) A-I      intronic chr5:60714252(+) A-I      intronic chr5:60659957(+) A-I      intronic chr5:60674999(+) A-I      intronic chr5:60663132(+) A-I      intronic chr5:60662505(+) A-I      intronic chr5:60641933(+) A-I      intronic chr5:60824698(+) A-I      intronic chr5:60689572(+) A-I      intronic chr5:60727093(+) A-I      intronic chr5:60824984(+) A-I      intronic chr5:60679519(+) A-I      intronic chr5:60673494(+) A-I      intronic chr5:60674630(+) A-I      intronic chr5:60674512(+) A-I      intronic chr5:60661813(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZSWIM6	chr5:60671169(+) A-I intron -    22327324 chr5:60663132(+) A-I intron -    21960545 chr5:60663183(+) A-I intron -    21960545 chr5:60673397(+) A-I intron -    21960545 chr5:60659923(+) A-G intron -    22484847 chr5:60659957(+) A-G intron -    22484847 chr5:60659984(+) A-G intron -    22484847 chr5:60661058(+) A-G intron -    22484847 chr5:60661081(+) A-G intron -    22484847 chr5:60661762(+) A-G intron -    22484847 chr5:60661763(+) A-G intron -    22484847 chr5:60661813(+) A-G intron -    22484847 chr5:60661826(+) A-G intron -    22484847 chr5:60661883(+) A-G intron -    22484847 chr5:60661922(+) A-G intron -    22484847 chr5:60662000(+) A-G intron -    22484847 chr5:60663132(+) A-G intron -    22484847 chr5:60663152(+) A-G intron -    22484847 chr5:60674476(+) A-G intron -    22484847 chr5:60674592(+) A-G intron -    22484847 chr5:60674743(+) A-G intron -    22484847 chr5:60674765(+) A-G intron -    22484847 chr5:60679389(+) A-G intron -    22484847 chr5:60679814(+) A-G intron -    22484847 chr5:60688539(+) A-G intron -    22484847 chr5:60688966(+) A-G intron -    22484847 chr5:60699973(+) T-C intron -    22484847 chr5:60824983(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZSWIM6	chr5:60628113-60628114(+) m6A CDS       24981863 chr5:60628309-60628310(+) m6A CDS       24209618 chr5:60628334-60628335(+) m6A CDS       24284625//24209618 chr5:60628738-60628739(+) Y CDS       26075521 chr5:60628757-60628758(+) m6A CDS       24209618 chr5:60643329-60643330(+) m6A intron       22575960 chr5:60643347-60643348(+) m6A intron       22575960 chr5:60643365-60643366(+) m6A intron       22575960 chr5:60643373-60643374(+) m6A intron       22575960 chr5:60671140-60671141(+) m6A intron       27773535 chr5:60671153-60671154(+) m6A intron       27773535 chr5:60671162-60671163(+) m6A intron       27773535 chr5:60671210-60671211(+) m6A intron       27773535 chr5:60671601-60671602(+) m6A intron       27773535 chr5:60671627-60671628(+) m6A intron       27773535 chr5:60768535-60768536(+) m6A CDS       24209618//24981863//22608085 chr5:60768560-60768561(+) m6A CDS       24209618//24981863//22608085 chr5:60768627-60768628(+) m6A CDS       24284625//24981863//22608085 chr5:60768633-60768634(+) m6A CDS       24284625//24981863//22608085 chr5:60768700-60768701(+) m6A CDS       24284625//24981863//22608085 chr5:60768722-60768723(+) m6A CDS       24284625//24981863//22608085 chr5:60768744-60768745(+) m6A CDS       24284625//24981863//22608085 chr5:60821635-60821636(+) m6A CDS       - chr5:60821649-60821650(+) m6A CDS       - chr5:60821764-60821765(+) m6A CDS       - chr5:60839296-60839297(+) m6A CDS       24284625//24209618//24981863 chr5:60839310-60839311(+) m6A CDS       24284625//24209618//24981863//22608085 chr5:60839401-60839402(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr5:60839439-60839440(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr5:60839476-60839477(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr5:60839686-60839687(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr5:60839812-60839813(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:60839855-60839856(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:60839872-60839873(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:60839896-60839897(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:60840027-60840028(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr5:60840050-60840051(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr5:60840086-60840087(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr5:60840110-60840111(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr5:60840516-60840517(+) m6A 3'UTR       24981863 chr5:60840521-60840522(+) m6A 3'UTR       24981863 chr5:60840526-60840527(+) m6A 3'UTR       24981863 chr5:60840609-60840610(+) m6A 3'UTR       24981863 chr5:60840712-60840713(+) m6A 3'UTR       24981863 chr5:60840899-60840900(+) m6A 3'UTR       24981863//22608085 chr5:60840905-60840906(+) m6A 3'UTR       24981863//22608085 chr5:60840916-60840917(+) m6A 3'UTR       24981863//22608085 chr5:60840927-60840928(+) m6A 3'UTR       24981863//22608085 chr5:60840940-60840941(+) m6A 3'UTR       24981863//22608085 chr5:60840981-60840982(+) m6A 3'UTR       24981863//22608085 chr5:60841031-60841032(+) m6A 3'UTR       24981863//22608085 chr5:60841111-60841112(+) m6A 3'UTR       24981863//27773535//22608085 chr5:60841182-60841183(+) m6A 3'UTR       24981863//27773535//22608085 chr5:60841271-60841272(+) m6A 3'UTR       24981863 chr5:60841300-60841301(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-185-5p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Plasma     29130611 Exosome Primary dendritic cells|T cell line (J77)     21505438 Exosome Breast milk     22211110 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Serum     25135963 Exosome Blood|Tongue tissue     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	ZSWIM6	Chromatin K562 cells     - Cytosol HeLa-S3 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-185-5p	7-Epi-10-deacetylbaccatin III 9872117 Drug sensitive Midostaurin 9829523 Drug resistant Tiotixene 941651 Drug sensitive Acridine Yellow G 8672 Drug resistant 1,9-Pyrazoloanthrone 8515 Drug resistant Pingyangmycin 84046 Drug resistant Tanakan 83818 Drug sensitive 2,4,6-Tris(2-pyridyl)-s-triazine 77258 Drug sensitive Secalonic acid D 73431 Drug sensitive Coptisine chloride 72321 Drug sensitive 7-Hydroxystaurosporine 72271 Drug resistant Anaxirone 71218 Drug resistant Dihydroxydiphenyl-pyridyl methane 69046 Drug resistant Mevastatin 64715 Drug resistant Everolimus 6442177 Drug resistant Primaquine phosphate 6135 Drug sensitive 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive 8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive Thiopyrimidine-CH3 5473238 Drug sensitive Iejimalide A. 5473233 Drug sensitive 11-Cyanomethylen-11H-indolo[1,2-a]indazole 5472501 Drug resistant 6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive Bleomycin 5460769 Drug resistant Herveline O 5459269 Drug sensitive [2-[2-[(1R,2S)-2-[[6-Amino-2-[1-[(2S)-2,3-diamino-3-oxopropyl]-4-oxoazetidin-2-yl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4S)-3-hydroxy-5-[[(2S,3R)-3-hydroxy-1-[2-[4-[4-[2-(2-hydroxypropylamino)ethylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate 5458321 Drug resistant Melampodin B acetate 5359212 Drug sensitive 5-Methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 Drug sensitive Lovastatin 53232 Drug resistant Cytochalasin B 5311281 Drug resistant Herbimycin 5311102 Drug sensitive 5-Fluoro-2'-deoxycytidine 515328 Drug resistant Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498558 Drug sensitive Staurosporine, 98% 49831000 Drug resistant 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 4713 Drug sensitive Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive 3-3'-(1H-Pyrazole-3,5-diyl)bis(1-methyl-1H-indole) 44433919 Drug resistant 4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine 44397453 Drug resistant 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Bleomycin-BAPP 431594 Drug resistant Bleomycin A5, sulfate 422920 Drug resistant Aminopyrimidine-CH3 406278 Drug sensitive 1H-Naphth[2,3-d]imidazole, 2-[(4-chlorophenyl)methyl]- 405626 Drug resistant Purpureagitosid 401298 Drug resistant Trapoxin B 395803 Drug sensitive 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant 2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive 2-(3-Chloropropyloxy)naphthazarin 378771 Drug sensitive 5,8-Dihydroxy-2-(4-(2-pyridinyl)-1-piperazinyl)naphthoquinone 376947 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant 2,3-Bis(dodecanoyloxy)propylarsonic acid 375754 Drug sensitive Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant 1-(4-Methoxy-2-methylphenyl)naphtho[1,2-c]furan-3(1H)-one 369148 Drug sensitive 3,8,13,18,23-Pentaazapentacosane 368998 Drug sensitive 2,7-Dicyanoxanthone 363841 Drug sensitive Girolline 362388 Drug resistant 1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)- 362170 Drug sensitive 7alpha-Acetoxyroylenane 362048 Drug sensitive Thiosangivamycin 3580213 Drug sensitive Imidazole, 1-(4-chlorophenyl)-4-(4-nitrophenyl)- 355940 Drug resistant 2,3-Dimethylbenzo[g]quinoxaline-5,10-dione 353644 Drug sensitive 1,4-Diaminoanthraquinone 31420 Drug resistant Clomifene citrate 3033832 Drug sensitive SMA-491 (free base of NSC D742838) 302576 Drug resistant Gardenin A 261859 Drug resistant Hookerianamide J 25016666 Drug sensitive Hookerianamide K 25016412 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive CID 24197685 24197685 Drug sensitive Antibiotic U 29135 24196291 Drug sensitive 4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive Kinetin riboside 20345 Drug resistant Chonemorphine 165208 Drug sensitive (6R)-1,6,11-Trihydroxy-8-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-3-methyl-5,6-dihydrobenzo[a]anthracene-7,12-dione 15507920 Drug sensitive Ellipticine analog 148569 Drug resistant (2R)-2-Hydroxy-3-[(6R)-11-hydroxy-2-[4-[(6R)-4-hydroxy-2-[1-hydroxy-3-[(6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-methylpropanoic acid 146158002 Drug sensitive Astrazon Orange R 135747272 Drug sensitive [(8Ar)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate 134694047 Drug resistant Methyl (1S,10R,11S,12S)-11-acetyloxy-12-ethyl-4-[(13R,15R,17R)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 133126830 Drug sensitive (2R,4R,6S,7S,12S)-6,7,16-Trihydroxy-18-methoxy-12-methyl-3,13-dioxatricyclo[13.4.0.02,4]nonadeca-1(15),9,16,18-tetraene-8,14-dione 131676399 Drug sensitive 1,4-Bis((2-aminoethyl)amino)-5,8-dihydroxy-9,10-anthraquinone 125982 Drug resistant Pepleo 122804 Drug resistant Cyanoaminopyranopyridine derivatives 11494577 Drug resistant 1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug resistant Uridine, 2'-deoxy-2'-methylene- 11075548 Drug resistant Acetylenedicarboxamide 10971 Drug sensitive Cladospirone bisepoxide 10316810 Drug sensitive Binimetinib 10288191 Drug sensitive (1S,3R,6R,12S,14R,15S,18R,19E,21Z,25R,26S,27R)-6,15-Dihydroxy-18-[(1R)-1-hydroxyethyl]-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione 101307863 Drug sensitive Selumetinib 10127622 Drug sensitive 1,3,6-triphenyl-oxazolo(5,4-d)pyrimidin-2',4(1h,3h)-dion - Drug resistant 1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant 1-naphthalenecarboxamide, n,n'-1,8-(octanediyl)bis- - Drug resistant 6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant 3-peg fudr (peg floxuridine) - Drug resistant 6-aryl alkyl fluoro quinolone derivative - Drug resistant Annamycin Liposomal - Drug resistant antineoplastic-d655481 - Drug resistant Camptothecin Derivative - Drug resistant geldanamycin dimethylglycinate - Drug resistant organosulfur compound - Drug resistant tartrolon a1 - Drug resistant toxin .delta.53l - Drug resistant tp4ek - Drug resistant viridomycin - Drug resistant (z) 3,3',4,5-tetramethoxystilbene - Drug sensitive 1,2-benzo-8-(d,l-alanyl)-3-phenoxazone nitrate salt - Drug sensitive 1-piperidinecarbodithioic acid, antimony complex - Drug sensitive 2-azabicyclo[16.3.1]docosane, geldanamycin deriv. - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug sensitive benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive iodonium, (4-methoxyphenyl)(3-methylphenyl)-, bromide - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive 5-hydroxyamino camptothecin - Drug sensitive antineoplastic-615538 - Drug sensitive dichlorobisoxinatotitanium(iv) - Drug sensitive geldanamycin deriv - Drug sensitive tetra(isobutenyl)antimony bromide - Drug sensitive xenorhabdin 1 - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-185-5p	Formaldehyde 712 Drug interaction    RC00003208 Oxaliplatine 6857599 Drug interaction    RC00003218 Gemcitabine 60750 Drug interaction    RC00003213 Cholesterol 5997 Drug interaction    RC00003211 Eloxatine 5310940 Drug interaction    RC00003217 Decitabine 451668 Drug interaction    RC00003215 5-Fluorouracil 3385 Drug interaction    RC00003210 Doxorubicin 31703 Drug interaction    RC00003212 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00003209 Tamoxifen 2733526 Drug interaction    RC00003216 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00003219 Benzene 241 Drug interaction    RC00003207 Leucovorin 135403648 Drug interaction    RC00003220

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-185-5p	Cisplatin 5702198       27906433 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-185-5p
Interactor2: ZSWIM6

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.