Basic Information:

  VIRBase ID:  

HHID00053240

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-185-5p:  MIMAT0000455          PMF1:  NM_001393910     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-185-5p	PMF1
miRBase Accession/Entrez ID	MIMAT0000455	11243
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-185-5p	rs1249170072 chr22:20033164    G/A rs770235403 chr22:20033168    T/C rs775856637 chr22:20033173    G/A rs1398989482 chr22:20033154    G/A rs761385932 chr22:20033159    GAA/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PMF1	chr1:156195908(+) A-I      intronic chr1:156200852(+) A-I      intronic chr1:156183844(+) A-I      intronic chr1:156194817(+) A-I      intronic chr1:156194943(+) A-I      intronic chr1:156197523(+) A-I      intronic chr1:156194951(+) A-I      intronic chr1:156194830(+) A-I      intronic chr1:156195906(+) A-I      intronic chr1:156185536(+) A-I      intronic chr1:156194960(+) A-I      intronic chr1:156185541(+) A-I      intronic chr1:156194994(+) A-I      intronic chr1:156195926(+) A-I      intronic chr1:156187429(+) A-I      intronic chr1:156194989(+) A-I      intronic chr1:156188858(+) A-I      intronic chr1:156188866(+) A-I      intronic chr1:156183832(+) A-I      intronic chr1:156185959(+) A-I      intronic chr1:156201426(+) A-I      intronic chr1:156197572(+) A-I      intronic chr1:156195880(+) A-I      intronic chr1:156188856(+) A-I      intronic chr1:156201475(+) A-I      intronic chr1:156186164(+) A-I      intronic chr1:156186088(+) A-I      intronic chr1:156197906(+) A-I      intronic chr1:156203747(+) A-I      intronic chr1:156185935(+) A-I      intronic chr1:156188848(+) A-I      intronic chr1:156197387(+) A-I      intronic chr1:156188295(+) A-I      intronic chr1:156188301(+) A-I      intronic chr1:156203592(+) A-I      intronic chr1:156188919(+) A-I      intronic chr1:156188944(+) A-I      intronic chr1:156194560(+) A-I      intronic chr1:156201439(+) A-I      intronic chr1:156198898(+) A-I      intronic chr1:156201419(+) A-I      intronic chr1:156198884(+) A-I      intronic chr1:156201383(+) A-I      intronic chr1:156190016(+) A-I      intronic chr1:156195732(+) A-I      intronic chr1:156188361(+) A-I      intronic chr1:156200760(+) A-I      intronic chr1:156188385(+) A-I      intronic chr1:156201374(+) A-I      intronic chr1:156198769(+) A-I      intronic chr1:156201373(+) A-I      intronic chr1:156185947(+) A-I      intronic chr1:156200595(+) A-I      intronic chr1:156194827(+) A-I      intronic chr1:156185983(+) A-I      intronic chr1:156199461(+) A-I      intronic chr1:156200757(+) A-I      intronic chr1:156200579(+) A-I      intronic chr1:156201347(+) A-I      intronic chr1:156197136(+) A-I      intronic chr1:156188387(+) A-I      intronic chr1:156188395(+) A-I      intronic chr1:156188410(+) A-I      intronic chr1:156188423(+) A-I      intronic chr1:156188434(+) A-I      intronic chr1:156188962(+) A-I      intronic chr1:156194398(+) A-I      intronic chr1:156194741(+) A-I      intronic chr1:156198793(+) A-I      intronic chr1:156192329(+) A-I      intronic chr1:156201341(+) A-I      intronic chr1:156186004(+) A-I      intronic chr1:156192303(+) A-I      intronic chr1:156188485(+) A-I      intronic chr1:156198841(+) A-I      intronic chr1:156199405(+) A-I      intronic chr1:156194356(+) A-I      intronic chr1:156190205(+) A-I      intronic chr1:156186084(+) A-I      intronic chr1:156197119(+) A-I      intronic chr1:156194565(+) A-I      intronic chr1:156198935(+) A-I      intronic chr1:156192340(+) A-I      intronic chr1:156190682(+) A-I      intronic chr1:156201335(+) A-I      intronic chr1:156198901(+) A-I      intronic chr1:156192508(+) A-I      intronic chr1:156190188(+) A-I      intronic chr1:156190086(+) A-I      intronic chr1:156188838(+) A-I      intronic chr1:156198875(+) A-I      intronic chr1:156188834(+) A-I      intronic chr1:156201333(+) A-I      intronic chr1:156188812(+) A-I      intronic chr1:156194318(+) A-I      intronic chr1:156188809(+) A-I      intronic chr1:156188808(+) A-I      intronic chr1:156200643(+) A-I      intronic chr1:156188762(+) A-I      intronic chr1:156199498(+) A-I      intronic chr1:156188518(+) A-I      intronic chr1:156200698(+) A-I      intronic chr1:156188494(+) A-I      intronic chr1:156188446(+) A-I      intronic chr1:156185932(+) A-I      intronic chr1:156190705(+) A-I      intronic chr1:156192254(+) A-I      intronic chr1:156190257(+) A-I      intronic chr1:156185629(+) A-I      intronic chr1:156188984(+) A-I      intronic chr1:156185619(+) A-I      intronic chr1:156185560(+) A-I      intronic chr1:156186177(+) A-I      intronic chr1:156187297(+) A-I      intronic chr1:156185559(+) A-I      intronic chr1:156201318(+) A-I      intronic chr1:156185411(+) A-I      intronic chr1:156185373(+) A-I      intronic chr1:156199466(+) A-I      intronic chr1:156184929(+) A-I      intronic chr1:156201308(+) A-I      intronic chr1:156187302(+) A-I      intronic chr1:156195763(+) A-I      intronic chr1:156184870(+) A-I      intronic chr1:156184835(+) A-I      intronic chr1:156189438(+) A-I      intronic chr1:156189518(+) A-I      intronic chr1:156201307(+) A-I      intronic chr1:156184834(+) A-I      intronic chr1:156187311(+) A-I      intronic chr1:156184440(+) A-I      intronic chr1:156184414(+) A-I      intronic chr1:156201293(+) A-I      intronic chr1:156183970(+) A-I      intronic chr1:156197133(+) A-I      intronic chr1:156183936(+) A-I      intronic chr1:156192313(+) A-I      intronic chr1:156192560(+) A-I      intronic chr1:156183907(+) A-I      intronic chr1:156189872(+) A-I      intronic chr1:156183904(+) A-I      intronic chr1:156183802(+) A-I      intronic chr1:156187432(+) A-I      intronic chr1:156198960(+) A-I      intronic chr1:156194440(+) A-I      intronic chr1:156183264(+) A-I      intronic chr1:156203816(+) A-I      intronic chr1:156188469(+) A-I      intronic chr1:156200707(+) A-I      intronic chr1:156200751(+) A-I      intronic chr1:156189859(+) A-I      intronic chr1:156201292(+) A-I      intronic chr1:156189658(+) A-I      intronic chr1:156200814(+) A-I      intronic chr1:156195746(+) A-I      intronic chr1:156198800(+) A-I      intronic chr1:156201255(+) A-I      intronic chr1:156189774(+) A-I      intronic chr1:156189998(+) A-I      intronic chr1:156198817(+) A-I      intronic chr1:156201284(+) A-I      intronic chr1:156195739(+) A-I      intronic chr1:156195911(+) A-I      intronic chr1:156201274(+) A-I      intronic chr1:156201247(+) A-I      intronic chr1:156197405(+) A-I      intronic chr1:156201332(+) A-I      intronic chr1:156197164(+) A-I      intronic chr1:156201238(+) A-I      intronic chr1:156201134(+) A-I      intronic chr1:156197674(+) A-I      intronic chr1:156201093(+) A-I      intronic chr1:156200901(+) A-I      intronic chr1:156200861(+) A-I      intronic chr1:156197144(+) A-I      intronic chr1:156200847(+) A-I      intronic chr1:156200846(+) A-I      intronic chr1:156200803(+) A-I      intronic chr1:156189894(+) A-I      intronic chr1:156197806(+) A-I      intronic chr1:156200790(+) A-I      intronic chr1:156186023(+) A-I      intronic chr1:156185435(+) A-I      intronic chr1:156200672(+) A-I      intronic chr1:156200752(+) A-I      intronic chr1:156194971(+) A-I      intronic chr1:156183803(+) A-I      intronic chr1:156184522(+) A-I      intronic chr1:156189702(+) A-I      intronic chr1:156200844(+) A-I      intronic chr1:156200620(+) A-I      intronic chr1:156187341(+) A-I      intronic chr1:156197139(+) A-I      intronic chr1:156184906(+) A-I      intronic chr1:156197562(+) A-I      intronic chr1:156201239(+) A-I      intronic chr1:156185920(+) A-I      intronic chr1:156190240(+) A-I      intronic chr1:156185910(+) A-I      intronic chr1:156197175(+) A-I      intronic chr1:156200606(+) A-I      intronic chr1:156186067(+) A-I      intronic chr1:156189621(+) A-I      intronic chr1:156207715(+) A-I      intronic chr1:156186102(+) A-I      intronic chr1:156197093(+) A-I      intronic chr1:156200888(+) A-I      intronic chr1:156200887(+) A-I      intronic chr1:156185580(+) A-I      intronic chr1:156187396(+) A-I      intronic chr1:156188393(+) A-I      intronic chr1:156189456(+) A-I      intronic chr1:156190279(+) A-I      intronic chr1:156187454(+) A-I      intronic chr1:156183973(+) A-I      intronic chr1:156203195(+) A-I      intronic chr1:156189707(+) A-I      intronic chr1:156195907(+) A-I      intronic chr1:156188972(+) A-I      intronic chr1:156187384(+) A-I      intronic chr1:156183897(+) A-I      intronic chr1:156200674(+) A-I      intronic chr1:156186011(+) A-I      intronic chr1:156188907(+) A-I      intronic chr1:156190681(+) A-I      intronic chr1:156199501(+) A-I      intronic chr1:156186045(+) A-I      intronic chr1:156197024(+) A-I      intronic chr1:156186000(+) A-I      intronic chr1:156190135(+) A-I      intronic chr1:156189653(+) A-I      intronic chr1:156194920(+) A-I      intronic chr1:156184516(+) A-I      intronic chr1:156198007(+) A-I      intronic chr1:156203870(+) A-I      intronic chr1:156203607(+) A-I      intronic chr1:156187370(+) A-I      intronic chr1:156184449(+) A-I      intronic chr1:156206915(+) A-I      intronic chr1:156203590(+) A-I      intronic chr1:156207689(+) A-I      intronic chr1:156203668(+) A-I      intronic chr1:156183286(+) A-I      intronic chr1:156189564(+) A-I      intronic chr1:156188316(+) A-I      intronic chr1:156187330(+) A-I      intronic chr1:156190191(+) A-I      intronic chr1:156194434(+) A-I      intronic chr1:156188892(+) A-I      intronic chr1:156189706(+) A-I      intronic chr1:156189516(+) A-I      intronic chr1:156196829(+) A-I      intronic chr1:156201244(+) A-I      intronic chr1:156187355(+) A-I      intronic chr1:156197039(+) A-I      intronic chr1:156203733(+) A-I      intronic chr1:156197094(+) A-I      intronic chr1:156186035(+) A-I      intronic chr1:156195829(+) A-I      intronic chr1:156197910(+) A-I      intronic chr1:156184902(+) A-I      intronic chr1:156195867(+) A-I      intronic chr1:156201232(+) A-I      intronic chr1:156197826(+) A-I      intronic chr1:156197427(+) A-I      intronic chr1:156185926(+) A-I      intronic chr1:156183395(+) A-I      intronic chr1:156199479(+) A-I      intronic chr1:156183758(+) A-I      intronic chr1:156192230(+) A-I      intronic chr1:156202540(+) A-I      intronic chr1:156197909(+) A-I      intronic chr1:156184413(+) A-I      intronic chr1:156199607(+) A-I      intronic chr1:156184699(+) A-I      intronic chr1:156184867(+) A-I      intronic chr1:156185646(+) A-I      intronic chr1:156185641(+) A-I      intronic chr1:156187307(+) A-I      intronic chr1:156203806(+) A-I      intronic chr1:156190233(+) A-I      intronic chr1:156185548(+) A-I      intronic chr1:156197865(+) A-I      intronic chr1:156195677(+) A-I      intronic chr1:156184748(+) A-I      intronic chr1:156189940(+) A-I      intronic chr1:156186110(+) A-I      intronic chr1:156186006(+) A-I      intronic chr1:156192278(+) A-I      intronic chr1:156197511(+) A-I      intronic chr1:156192235(+) A-I      intronic chr1:156183979(+) A-I      intronic chr1:156190090(+) A-I      intronic chr1:156207699(+) A-I      intronic chr1:156187383(+) A-I      intronic chr1:156197130(+) A-I      intronic chr1:156197550(+) A-I      intronic chr1:156200845(+) A-I      intronic chr1:156184808(+) A-I      intronic chr1:156194271(+) A-I      intronic chr1:156188323(+) A-I      intronic chr1:156199547(+) A-I      intronic chr1:156187397(+) A-I      intronic chr1:156195704(+) A-I      intronic chr1:156197145(+) A-I      intronic chr1:156184454(+) A-I      intronic chr1:156197174(+) A-I      intronic chr1:156186103(+) A-I      intronic chr1:156200850(+) A-I      intronic chr1:156203793(+) A-I      intronic chr1:156189596(+) A-I      intronic chr1:156203642(+) A-I      intronic chr1:156197524(+) A-I      intronic chr1:156194953(+) A-I      intronic chr1:156183842(+) A-I      intronic chr1:156184769(+) A-I      intronic chr1:156198967(+) A-I      intronic chr1:156188881(+) A-I      intronic chr1:156201112(+) A-I      intronic chr1:156194874(+) A-I      intronic chr1:156185451(+) A-I      intronic chr1:156186111(+) A-I      intronic chr1:156197469(+) A-I      intronic chr1:156194335(+) A-I      intronic chr1:156183890(+) A-I      intronic chr1:156183355(+) A-I      intronic chr1:156203852(+) A-I      intronic chr1:156184803(+) A-I      intronic chr1:156183330(+) A-I      intronic chr1:156194312(+) A-I      intronic chr1:156201440(+) A-I      intronic chr1:156187460(+) A-I      intronic chr1:156192217(+) A-I      intronic chr1:156188813(+) A-I      intronic chr1:156194444(+) A-I      intronic chr1:156201449(+) A-I      intronic chr1:156188334(+) A-I      intronic chr1:156187442(+) A-I      intronic chr1:156197216(+) A-I      intronic chr1:156188889(+) A-I      intronic chr1:156197551(+) A-I      intronic chr1:156197417(+) A-I      intronic chr1:156185418(+) A-I      intronic chr1:156203684(+) A-I      intronic chr1:156186139(+) A-I      intronic chr1:156185962(+) A-I      intronic chr1:156186017(+) A-I      intronic chr1:156190017(+) A-I      intronic chr1:156197048(+) A-I      intronic chr1:156185503(+) A-I      intronic chr1:156198021(+) A-I      intronic chr1:156187469(+) A-I      intronic chr1:156194378(+) A-I      intronic chr1:156201443(+) A-I      intronic chr1:156186061(+) A-I      intronic chr1:156189680(+) A-I      intronic chr1:156200624(+) A-I      intronic chr1:156203784(+) A-I      intronic chr1:156194348(+) A-I      intronic chr1:156187352(+) A-I      intronic chr1:156188392(+) A-I      intronic chr1:156200774(+) A-I      intronic chr1:156197388(+) A-I      intronic chr1:156189463(+) A-I      intronic chr1:156186094(+) A-I      intronic chr1:156199418(+) A-I      intronic chr1:156189962(+) A-I      intronic chr1:156199544(+) A-I      intronic chr1:156183820(+) A-I      intronic chr1:156189477(+) A-I      intronic chr1:156200716(+) A-I      intronic chr1:156194313(+) A-I      intronic chr1:156185393(+) A-I      intronic chr1:156199625(+) A-I      intronic chr1:156194965(+) A-I      intronic chr1:156197563(+) A-I      intronic chr1:156195723(+) A-I      intronic chr1:156201094(+) A-I      intronic chr1:156197782(+) A-I      intronic chr1:156199592(+) A-I      intronic chr1:156187340(+) A-I      intronic chr1:156197795(+) A-I      intronic chr1:156187419(+) A-I      intronic chr1:156203744(+) A-I      intronic chr1:156184688(+) A-I      intronic chr1:156186085(+) A-I      intronic chr1:156201080(+) A-I      intronic chr1:156199626(+) A-I      intronic chr1:156197118(+) A-I      intronic chr1:156203654(+) A-I      intronic chr1:156187267(+) A-I      intronic chr1:156185663(+) A-I      intronic chr1:156194755(+) A-I      intronic chr1:156188362(+) A-I      intronic chr1:156188452(+) A-I      intronic chr1:156186152(+) A-I      intronic chr1:156197843(+) A-I      intronic chr1:156197220(+) A-I      intronic chr1:156188406(+) A-I      intronic chr1:156205254(+) A-I      intronic chr1:156206965(+) A-I      intronic chr1:156189937(+) A-I      intronic chr1:156190029(+) A-I      intronic chr1:156200733(+) A-I      intronic chr1:156189400(+) A-I      intronic chr1:156185927(+) A-I      intronic chr1:156194938(+) A-I      intronic chr1:156187239(+) A-I      intronic chr1:156194795(+) A-I      intronic chr1:156190131(+) A-I      intronic chr1:156194408(+) A-I      intronic chr1:156188426(+) A-I      intronic chr1:156189966(+) A-I      intronic chr1:156207627(+) A-I      intronic chr1:156183804(+) A-I      intronic chr1:156197075(+) A-I      intronic chr1:156184773(+) A-I      intronic chr1:156184462(+) A-I      intronic chr1:156201444(+) A-I      intronic chr1:156200589(+) A-I      intronic chr1:156186031(+) A-I      intronic chr1:156185366(+) A-I      intronic chr1:156184859(+) A-I      intronic chr1:156184755(+) A-I      intronic chr1:156183342(+) A-I      intronic chr1:156185645(+) A-I      intronic chr1:156201066(+) A-I      intronic chr1:156197056(+) A-I      intronic chr1:156184509(+) A-I      intronic chr1:156203800(+) A-I      intronic chr1:156184786(+) A-I      intronic chr1:156194820(+) A-I      intronic chr1:156183335(+) A-I      intronic chr1:156197931(+) A-I      intronic chr1:156186062(+) A-I      intronic chr1:156192260(+) A-I      intronic chr1:156194321(+) A-I      intronic chr1:156199564(+) A-I      intronic chr1:156197184(+) A-I      intronic chr1:156188475(+) A-I      intronic chr1:156187402(+) A-I      intronic chr1:156183892(+) A-I      intronic chr1:156187262(+) A-I      intronic chr1:156192267(+) A-I      intronic chr1:156203667(+) A-I      intronic chr1:156195866(+) A-I      intronic chr1:156184830(+) A-I      intronic chr1:156197461(+) A-I      intronic chr1:156194865(+) A-I      intronic chr1:156190129(+) A-I      intronic chr1:156187261(+) A-I      intronic chr1:156199549(+) A-I      intronic chr1:156199431(+) A-I      intronic chr1:156192407(+) A-I      intronic chr1:156200670(+) A-I      intronic chr1:156187381(+) A-I      intronic chr1:156184947(+) A-I      intronic chr1:156188786(+) A-I      intronic chr1:156184853(+) A-I      intronic chr1:156187423(+) A-I      intronic chr1:156204429(+) A-I      intronic chr1:156189727(+) A-I      intronic chr1:156185579(+) A-I      intronic chr1:156194956(+) A-I      intronic chr1:156194856(+) A-I      intronic chr1:156186032(+) A-I      intronic chr1:156194272(+) A-I      intronic chr1:156197472(+) A-I      intronic chr1:156186131(+) A-I      intronic chr1:156184941(+) A-I      intronic chr1:156198009(+) A-I      intronic chr1:156188791(+) A-I      intronic chr1:156194525(+) A-I      intronic chr1:156194952(+) A-I      intronic chr1:156195881(+) A-I      intronic chr1:156199462(+) A-I      intronic chr1:156197565(+) A-I      intronic chr1:156194871(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PMF1	chr1:156182933-156182934(+) m6A CDS//exon       24981863//22575960 chr1:156206146-156206147(+) m6A 3'UTR//CDS//exon       24209618//22575960 chr1:156206171-156206172(+) m6A 3'UTR//CDS//exon       24209618//22575960 chr1:156206185-156206186(+) m6A 3'UTR//CDS//exon       24209618//24981863//22575960 chr1:156206365-156206366(+) m6A exon//intron       24209618 chr1:156207078-156207079(+) m6A exon//intron       24209618 chr1:156209352-156209353(+) m6A 3'UTR//CDS       24209618 chr1:156209396-156209397(+) m6A 3'UTR       24209618 chr1:156209529-156209530(+) m6A 3'UTR       24284625//24981863//22575960 chr1:156209585-156209586(+) m6A 3'UTR       24284625//24981863//22575960 chr1:156209812-156209813(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-185-5p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Plasma     29130611 Exosome Primary dendritic cells|T cell line (J77)     21505438 Exosome Breast milk     22211110 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Serum     25135963 Exosome Blood|Tongue tissue     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	PMF1	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-185-5p	7-Epi-10-deacetylbaccatin III 9872117 Drug sensitive Midostaurin 9829523 Drug resistant Tiotixene 941651 Drug sensitive Acridine Yellow G 8672 Drug resistant 1,9-Pyrazoloanthrone 8515 Drug resistant Pingyangmycin 84046 Drug resistant Tanakan 83818 Drug sensitive 2,4,6-Tris(2-pyridyl)-s-triazine 77258 Drug sensitive Secalonic acid D 73431 Drug sensitive Coptisine chloride 72321 Drug sensitive 7-Hydroxystaurosporine 72271 Drug resistant Anaxirone 71218 Drug resistant Dihydroxydiphenyl-pyridyl methane 69046 Drug resistant Mevastatin 64715 Drug resistant Everolimus 6442177 Drug resistant Primaquine phosphate 6135 Drug sensitive 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive 8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive Thiopyrimidine-CH3 5473238 Drug sensitive Iejimalide A. 5473233 Drug sensitive 11-Cyanomethylen-11H-indolo[1,2-a]indazole 5472501 Drug resistant 6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive Bleomycin 5460769 Drug resistant Herveline O 5459269 Drug sensitive [2-[2-[(1R,2S)-2-[[6-Amino-2-[1-[(2S)-2,3-diamino-3-oxopropyl]-4-oxoazetidin-2-yl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4S)-3-hydroxy-5-[[(2S,3R)-3-hydroxy-1-[2-[4-[4-[2-(2-hydroxypropylamino)ethylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate 5458321 Drug resistant Melampodin B acetate 5359212 Drug sensitive 5-Methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 Drug sensitive Lovastatin 53232 Drug resistant Cytochalasin B 5311281 Drug resistant Herbimycin 5311102 Drug sensitive 5-Fluoro-2'-deoxycytidine 515328 Drug resistant Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498558 Drug sensitive Staurosporine, 98% 49831000 Drug resistant 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 4713 Drug sensitive Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive 3-3'-(1H-Pyrazole-3,5-diyl)bis(1-methyl-1H-indole) 44433919 Drug resistant 4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine 44397453 Drug resistant 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Bleomycin-BAPP 431594 Drug resistant Bleomycin A5, sulfate 422920 Drug resistant Aminopyrimidine-CH3 406278 Drug sensitive 1H-Naphth[2,3-d]imidazole, 2-[(4-chlorophenyl)methyl]- 405626 Drug resistant Purpureagitosid 401298 Drug resistant Trapoxin B 395803 Drug sensitive 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant 2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive 2-(3-Chloropropyloxy)naphthazarin 378771 Drug sensitive 5,8-Dihydroxy-2-(4-(2-pyridinyl)-1-piperazinyl)naphthoquinone 376947 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant 2,3-Bis(dodecanoyloxy)propylarsonic acid 375754 Drug sensitive Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant 1-(4-Methoxy-2-methylphenyl)naphtho[1,2-c]furan-3(1H)-one 369148 Drug sensitive 3,8,13,18,23-Pentaazapentacosane 368998 Drug sensitive 2,7-Dicyanoxanthone 363841 Drug sensitive Girolline 362388 Drug resistant 1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)- 362170 Drug sensitive 7alpha-Acetoxyroylenane 362048 Drug sensitive Thiosangivamycin 3580213 Drug sensitive Imidazole, 1-(4-chlorophenyl)-4-(4-nitrophenyl)- 355940 Drug resistant 2,3-Dimethylbenzo[g]quinoxaline-5,10-dione 353644 Drug sensitive 1,4-Diaminoanthraquinone 31420 Drug resistant Clomifene citrate 3033832 Drug sensitive SMA-491 (free base of NSC D742838) 302576 Drug resistant Gardenin A 261859 Drug resistant Hookerianamide J 25016666 Drug sensitive Hookerianamide K 25016412 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive CID 24197685 24197685 Drug sensitive Antibiotic U 29135 24196291 Drug sensitive 4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive Kinetin riboside 20345 Drug resistant Chonemorphine 165208 Drug sensitive (6R)-1,6,11-Trihydroxy-8-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-3-methyl-5,6-dihydrobenzo[a]anthracene-7,12-dione 15507920 Drug sensitive Ellipticine analog 148569 Drug resistant (2R)-2-Hydroxy-3-[(6R)-11-hydroxy-2-[4-[(6R)-4-hydroxy-2-[1-hydroxy-3-[(6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-methylpropanoic acid 146158002 Drug sensitive Astrazon Orange R 135747272 Drug sensitive [(8Ar)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate 134694047 Drug resistant Methyl (1S,10R,11S,12S)-11-acetyloxy-12-ethyl-4-[(13R,15R,17R)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 133126830 Drug sensitive (2R,4R,6S,7S,12S)-6,7,16-Trihydroxy-18-methoxy-12-methyl-3,13-dioxatricyclo[13.4.0.02,4]nonadeca-1(15),9,16,18-tetraene-8,14-dione 131676399 Drug sensitive 1,4-Bis((2-aminoethyl)amino)-5,8-dihydroxy-9,10-anthraquinone 125982 Drug resistant Pepleo 122804 Drug resistant Cyanoaminopyranopyridine derivatives 11494577 Drug resistant 1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug resistant Uridine, 2'-deoxy-2'-methylene- 11075548 Drug resistant Acetylenedicarboxamide 10971 Drug sensitive Cladospirone bisepoxide 10316810 Drug sensitive Binimetinib 10288191 Drug sensitive (1S,3R,6R,12S,14R,15S,18R,19E,21Z,25R,26S,27R)-6,15-Dihydroxy-18-[(1R)-1-hydroxyethyl]-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione 101307863 Drug sensitive Selumetinib 10127622 Drug sensitive 1,3,6-triphenyl-oxazolo(5,4-d)pyrimidin-2',4(1h,3h)-dion - Drug resistant 1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant 1-naphthalenecarboxamide, n,n'-1,8-(octanediyl)bis- - Drug resistant 6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant 3-peg fudr (peg floxuridine) - Drug resistant 6-aryl alkyl fluoro quinolone derivative - Drug resistant Annamycin Liposomal - Drug resistant antineoplastic-d655481 - Drug resistant Camptothecin Derivative - Drug resistant geldanamycin dimethylglycinate - Drug resistant organosulfur compound - Drug resistant tartrolon a1 - Drug resistant toxin .delta.53l - Drug resistant tp4ek - Drug resistant viridomycin - Drug resistant (z) 3,3',4,5-tetramethoxystilbene - Drug sensitive 1,2-benzo-8-(d,l-alanyl)-3-phenoxazone nitrate salt - Drug sensitive 1-piperidinecarbodithioic acid, antimony complex - Drug sensitive 2-azabicyclo[16.3.1]docosane, geldanamycin deriv. - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug sensitive benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive iodonium, (4-methoxyphenyl)(3-methylphenyl)-, bromide - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive 5-hydroxyamino camptothecin - Drug sensitive antineoplastic-615538 - Drug sensitive dichlorobisoxinatotitanium(iv) - Drug sensitive geldanamycin deriv - Drug sensitive tetra(isobutenyl)antimony bromide - Drug sensitive xenorhabdin 1 - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-185-5p	Formaldehyde 712 Drug interaction    RC00003208 Oxaliplatine 6857599 Drug interaction    RC00003218 Gemcitabine 60750 Drug interaction    RC00003213 Cholesterol 5997 Drug interaction    RC00003211 Eloxatine 5310940 Drug interaction    RC00003217 Decitabine 451668 Drug interaction    RC00003215 5-Fluorouracil 3385 Drug interaction    RC00003210 Doxorubicin 31703 Drug interaction    RC00003212 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00003209 Tamoxifen 2733526 Drug interaction    RC00003216 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00003219 Benzene 241 Drug interaction    RC00003207 Leucovorin 135403648 Drug interaction    RC00003220

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-185-5p	Cisplatin 5702198       27906433 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-185-5p
Interactor2: PMF1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.