Basic Information:

  VIRBase ID:  

HHID00053224

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-185-5p:  MIMAT0000455          RREB1:  NM_001168344     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-185-5p	RREB1
miRBase Accession/Entrez ID	MIMAT0000455	6239
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	FINB//HNT//LZ321//RREB-1//Zep-1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-185-5p	rs1249170072 chr22:20033164    G/A rs770235403 chr22:20033168    T/C rs775856637 chr22:20033173    G/A rs1398989482 chr22:20033154    G/A rs761385932 chr22:20033159    GAA/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RREB1	chr6:7240995(+) A-I      intronic chr6:7178012(+) A-I      intronic chr6:7178108(+) A-I      intronic chr6:7178328(+) A-I      intronic chr6:7184712(+) A-I      intronic chr6:7177908(+) A-I      intronic chr6:7177893(+) A-I      intronic chr6:7188240(+) A-I      intronic chr6:7188241(+) A-I      intronic chr6:7188281(+) A-I      intronic chr6:7188553(+) A-I      intronic chr6:7194677(+) A-I      intronic chr6:7194693(+) A-I      intronic chr6:7177892(+) A-I      intronic chr6:7194719(+) A-I      intronic chr6:7200052(+) A-I      intronic chr6:7227240(+) A-I      intronic chr6:7227249(+) A-I      intronic chr6:7227273(+) A-I      intronic chr6:7227285(+) A-I      intronic chr6:7227312(+) A-I      intronic chr6:7227409(+) A-I      intronic chr6:7228755(+) A-I      intronic chr6:7228756(+) A-I      intronic chr6:7228786(+) A-I      intronic chr6:7228833(+) A-I      intronic chr6:7228931(+) A-I      intronic chr6:7177211(+) A-I      intronic chr6:7177431(+) A-I      intronic chr6:7177472(+) A-I      intronic chr6:7229061(+) A-I      intronic chr6:7233207(+) A-I      intronic chr6:7233208(+) A-I      intronic chr6:7233227(+) A-I      intronic chr6:7233228(+) A-I      intronic chr6:7237200(+) A-I      intronic chr6:7237205(+) A-I      intronic chr6:7237213(+) A-I      intronic chr6:7244275(+) A-I      intronic chr6:7244334(+) A-I      intronic chr6:7244405(+) A-I      intronic chr6:7244408(+) A-I      intronic chr6:7188259(+) A-I      intronic chr6:7122566(+) A-I      intronic chr6:7122573(+) A-I      intronic chr6:7122585(+) A-I      intronic chr6:7114484(+) A-I      intronic chr6:7122628(+) A-I      intronic chr6:7122638(+) A-I      intronic chr6:7122648(+) A-I      intronic chr6:7128960(+) A-I      intronic chr6:7120700(+) A-I      intronic chr6:7117778(+) A-I      intronic chr6:7117780(+) A-I      intronic chr6:7117794(+) A-I      intronic chr6:7118453(+) A-I      intronic chr6:7118543(+) A-I      intronic chr6:7119344(+) A-I      intronic chr6:7119422(+) A-I      intronic chr6:7119424(+) A-I      intronic chr6:7119428(+) A-I      intronic chr6:7120608(+) A-I      intronic chr6:7120612(+) A-I      intronic chr6:7233246(+) A-I      intronic chr6:7121286(+) A-I      intronic chr6:7121291(+) A-I      intronic chr6:7129059(+) A-I      intronic chr6:7129099(+) A-I      intronic chr6:7129106(+) A-I      intronic chr6:7157748(+) A-I      intronic chr6:7157749(+) A-I      intronic chr6:7157901(+) A-I      intronic chr6:7157932(+) A-I      intronic chr6:7160842(+) A-I      intronic chr6:7160860(+) A-I      intronic chr6:7160892(+) A-I      intronic chr6:7160973(+) A-I      intronic chr6:7160989(+) A-I      intronic chr6:7161023(+) A-I      intronic chr6:7163105(+) A-I      intronic chr6:7163182(+) A-I      intronic chr6:7163640(+) A-I      intronic chr6:7163754(+) A-I      intronic chr6:7168368(+) A-I      intronic chr6:7168373(+) A-I      intronic chr6:7168394(+) A-I      intronic chr6:7168408(+) A-I      intronic chr6:7168409(+) A-I      intronic chr6:7168413(+) A-I      intronic chr6:7172282(+) A-I      intronic chr6:7172399(+) A-I      intronic chr6:7173603(+) A-I      intronic chr6:7173632(+) A-I      intronic chr6:7173637(+) A-I      intronic chr6:7173638(+) A-I      intronic chr6:7173641(+) A-I      intronic chr6:7173651(+) A-I      intronic chr6:7173676(+) A-I      intronic chr6:7173810(+) A-I      intronic chr6:7173820(+) A-I      intronic chr6:7174027(+) A-I      intronic chr6:7177188(+) A-I      intronic chr6:7227296(+) A-I      intronic chr6:7227295(+) A-I      intronic chr6:7168330(+) A-I      intronic chr6:7168313(+) A-I      intronic chr6:7168311(+) A-I      intronic chr6:7177195(+) A-I      intronic chr6:7114472(+) A-I      intronic chr6:7114459(+) A-I      intronic chr6:7114455(+) A-I      intronic chr6:7114441(+) A-I      intronic chr6:7129046(+) A-I      intronic chr6:7121266(+) A-I      intronic chr6:7177274(+) A-I      intronic chr6:7120540(+) A-I      intronic chr6:7163156(+) A-I      intronic chr6:7114494(+) A-I      intronic chr6:7118537(+) A-I      intronic chr6:7228839(+) A-I      intronic chr6:7228872(+) A-I      intronic chr6:7160844(+) A-I      intronic chr6:7184701(+) A-I      intronic chr6:7168324(+) A-I      intronic chr6:7244375(+) A-I      intronic chr6:7188366(+) A-I      intronic chr6:7178340(+) A-I      intronic chr6:7178176(+) A-I      intronic chr6:7178030(+) A-I      intronic chr6:7178136(+) A-I      intronic chr6:7177384(+) A-I      intronic chr6:7174967(+) A-I      intronic chr6:7119447(+) A-I      intronic chr6:7188537(+) A-I      intronic chr6:7120548(+) A-I      intronic chr6:7194709(+) A-I      intronic chr6:7119486(+) A-I      intronic chr6:7227309(+) A-I      intronic chr6:7118057(+) A-I      intronic chr6:7163648(+) A-I      intronic chr6:7118454(+) A-I      intronic chr6:7163647(+) A-I      intronic chr6:7235800(+) A-I      intronic chr6:7118471(+) A-I      intronic chr6:7120420(+) A-I      intronic chr6:7174942(+) A-I      intronic chr6:7177248(+) A-I      intronic chr6:7168367(+) A-I      intronic chr6:7157480(+) A-I      intronic chr6:7120695(+) A-I      intronic chr6:7163646(+) A-I      intronic chr6:7227640(+) A-I      intronic chr6:7173892(+) A-I      intronic chr6:7118440(+) A-I      intronic chr6:7228857(+) A-I      intronic chr6:7227292(+) A-I      intronic chr6:7228941(+) A-I      intronic chr6:7120501(+) A-I      intronic chr6:7229082(+) A-I      intronic chr6:7118377(+) A-I      intronic chr6:7120576(+) A-I      intronic chr6:7120580(+) A-I      intronic chr6:7119470(+) A-I      intronic chr6:7130869(+) A-I      intronic chr6:7228813(+) A-I      intronic chr6:7227245(+) A-I      intronic chr6:7176379(+) A-I      intronic chr6:7178161(+) A-I      intronic chr6:7238571(+) A-I      intronic chr6:7126763(+) A-I      intronic chr6:7120632(+) A-I      intronic chr6:7245374(+) A-I      intronic chr6:7177906(+) A-I      intronic chr6:7223342(+) A-I      intronic chr6:7178302(+) A-I      intronic chr6:7173829(+) A-I      intronic chr6:7177194(+) A-I      intronic chr6:7126764(+) A-I      intronic chr6:7118466(+) A-I      intronic chr6:7120628(+) A-I      intronic chr6:7244297(+) A-I      intronic chr6:7244266(+) A-I      intronic chr6:7229080(+) A-I      intronic chr6:7121092(+) A-I      intronic chr6:7118528(+) A-I      intronic chr6:7120980(+) A-I      intronic chr6:7121357(+) A-I      intronic chr6:7157858(+) A-I      intronic chr6:7119419(+) A-I      intronic chr6:7167704(+) A-I      intronic chr6:7121009(+) A-I      intronic chr6:7174906(+) A-I      intronic chr6:7174865(+) A-I      intronic chr6:7227241(+) A-I      intronic chr6:7237298(+) A-I      intronic chr6:7120666(+) A-I      intronic chr6:7173963(+) A-I      intronic chr6:7120602(+) A-I      intronic chr6:7160484(+) A-I      intronic chr6:7188237(+) A-I      intronic chr6:7177208(+) A-I      intronic chr6:7188666(+) A-I      intronic chr6:7121127(+) A-I      intronic chr6:7119431(+) A-I      intronic chr6:7118534(+) A-I      intronic chr6:7120566(+) A-I      intronic chr6:7121132(+) A-I      intronic chr6:7172742(+) A-I      intronic chr6:7155758(+) A-I      intronic chr6:7119413(+) A-I      intronic chr6:7177819(+) A-I      intronic chr6:7227331(+) A-I      intronic chr6:7129055(+) A-I      intronic chr6:7157475(+) A-I      intronic chr6:7177192(+) A-I      intronic chr6:7228922(+) A-I      intronic chr6:7175025(+) A-I      intronic chr6:7119463(+) A-I      intronic chr6:7172203(+) A-I      intronic chr6:7168261(+) A-I      intronic chr6:7177818(+) A-I      intronic chr6:7238519(+) A-I      intronic chr6:7119464(+) A-I      intronic chr6:7131273(+) A-I      intronic chr6:7244624(+) A-I      intronic chr6:7157546(+) A-I      intronic chr6:7227212(+) A-I      intronic chr6:7157878(+) A-I      intronic chr6:7119490(+) A-I      intronic chr6:7118493(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RREB1	chr6:7222212(+) A-I intron -    19478186 chr6:7118377(+) A-G intron -    22484847 chr6:7118390(+) A-G intron -    22484847 chr6:7118440(+) A-G intron -    22484847 chr6:7118454(+) A-G intron -    22484847 chr6:7118466(+) A-G intron -    22484847 chr6:7118471(+) A-G intron -    22484847 chr6:7118493(+) A-G intron -    22484847 chr6:7118528(+) A-G intron -    22484847 chr6:7118537(+) A-G intron -    22484847 chr6:7119419(+) A-G intron -    22484847 chr6:7119437(+) A-G intron -    22484847 chr6:7119447(+) A-G intron -    22484847 chr6:7119463(+) A-G intron -    22484847 chr6:7119464(+) A-G intron -    22484847 chr6:7119470(+) A-G intron -    22484847 chr6:7119486(+) A-G intron -    22484847 chr6:7119490(+) A-G intron -    22484847 chr6:7119516(+) A-G intron -    22484847 chr6:7120420(+) A-G intron -    22484847 chr6:7120528(+) A-G intron -    22484847 chr6:7120531(+) A-G intron -    22484847 chr6:7120540(+) A-G intron -    22484847 chr6:7120566(+) A-G intron -    22484847 chr6:7120576(+) A-G intron -    22484847 chr6:7120580(+) A-G intron -    22484847 chr6:7120602(+) A-G intron -    22484847 chr6:7120628(+) A-G intron -    22484847 chr6:7120632(+) A-G intron -    22484847 chr6:7120666(+) A-G intron -    22484847 chr6:7120980(+) A-G intron -    22484847 chr6:7121092(+) A-G intron -    22484847 chr6:7121127(+) A-G intron -    22484847 chr6:7121132(+) A-G intron -    22484847 chr6:7121182(+) G-A intron -    22484847 chr6:7121266(+) A-G intron -    22484847 chr6:7121309(+) A-G intron -    22484847 chr6:7121357(+) A-G intron -    22484847 chr6:7121450(+) T-C intron -    22484847 chr6:7123483(+) C-T intron -    22484847 chr6:7123484(+) G-A intron -    22484847 chr6:7123488(+) T-C intron -    22484847 chr6:7123655(+) G-A intron -    22484847 chr6:7129055(+) A-G intron -    22484847 chr6:7130932(+) C-T intron -    22484847 chr6:7131038(+) T-C intron -    22484847 chr6:7131273(+) A-G intron -    22484847 chr6:7155563(+) A-G intron -    22484847 chr6:7155680(+) A-G intron -    22484847 chr6:7155758(+) A-G intron -    22484847 chr6:7157436(+) A-G intron -    22484847 chr6:7157878(+) A-G intron -    22484847 chr6:7160766(+) A-G intron -    22484847 chr6:7160922(+) C-T intron -    22484847 chr6:7163646(+) A-G intron -    22484847 chr6:7163647(+) A-G intron -    22484847 chr6:7163648(+) A-G intron -    22484847 chr6:7167687(+) A-G intron -    22484847 chr6:7167704(+) A-G intron -    22484847 chr6:7167748(+) A-G intron -    22484847 chr6:7168261(+) A-G intron -    22484847 chr6:7168367(+) A-G intron -    22484847 chr6:7168388(+) T-C intron -    22484847 chr6:7173631(+) T-C intron -    22484847 chr6:7173963(+) A-G intron -    22484847 chr6:7174865(+) A-G intron -    22484847 chr6:7174905(+) A-G intron -    22484847 chr6:7174906(+) A-G intron -    22484847 chr6:7174938(+) T-C intron -    22484847 chr6:7174942(+) A-G intron -    22484847 chr6:7174967(+) A-G intron -    22484847 chr6:7177192(+) A-G intron -    22484847 chr6:7177208(+) A-G intron -    22484847 chr6:7177248(+) A-G intron -    22484847 chr6:7177274(+) A-G intron -    22484847 chr6:7177384(+) A-G intron -    22484847 chr6:7177818(+) A-G intron -    22484847 chr6:7177819(+) A-G intron -    22484847 chr6:7177906(+) A-G intron -    22484847 chr6:7178030(+) A-G intron -    22484847 chr6:7178035(+) A-G intron -    22484847 chr6:7178161(+) A-G intron -    22484847 chr6:7178176(+) A-G intron -    22484847 chr6:7184701(+) A-G intron -    22484847 chr6:7185524(+) C-T intron -    22484847 chr6:7188366(+) A-G intron -    22484847 chr6:7188537(+) A-G intron -    22484847 chr6:7188666(+) A-G intron -    22484847 chr6:7194709(+) A-G intron -    22484847 chr6:7197761(+) A-T intron -    22484847 chr6:7213659(+) T-C intron -    22484847 chr6:7215688(+) A-G intron -    22484847 chr6:7222986(+) A-G intron -    22484847 chr6:7223226(+) A-G intron -    22484847 chr6:7227241(+) A-G intron -    22484847 chr6:7227292(+) A-G intron -    22484847 chr6:7227309(+) A-G intron -    22484847 chr6:7227640(+) A-G intron -    22484847 chr6:7228839(+) A-G intron -    22484847 chr6:7228872(+) A-G intron -    22484847 chr6:7228883(+) A-G intron -    22484847 chr6:7228912(+) A-G intron -    22484847 chr6:7228922(+) A-G intron -    22484847 chr6:7228924(+) A-G intron -    22484847 chr6:7228941(+) A-G intron -    22484847 chr6:7229015(+) A-G intron -    22484847 chr6:7229080(+) A-G intron -    22484847 chr6:7237618(+) C-T intron -    22484847 chr6:7238519(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RREB1	chr6:7107963-7107964(+) m6A 5'UTR       24981863 chr6:7108165-7108166(+) m6A 5'UTR//intron       24284625//25456834 chr6:7108207-7108208(+) m6A 5'UTR//intron       24284625 chr6:7182181-7182182(+) m6A CDS//exon       24981863 chr6:7211059-7211060(+) m6A CDS//exon       24981863 chr6:7211129-7211130(+) m6A CDS//exon       24981863 chr6:7211161-7211162(+) m6A CDS//exon       24981863 chr6:7229340-7229341(+) m6A CDS       24284625//25456834//22575960 chr6:7229356-7229357(+) m6A CDS       24284625//25456834//24981863 chr6:7229407-7229408(+) m6A CDS       24284625//25456834//24981863//22608085 chr6:7229514-7229515(+) m6A CDS       24284625//25456834//24981863 chr6:7229539-7229540(+) m6A CDS       24284625//25456834//24981863 chr6:7229626-7229627(+) m6A CDS       24284625//24981863 chr6:7229737-7229738(+) m6A CDS       24284625 chr6:7230036-7230037(+) m6A CDS       22575960 chr6:7230127-7230128(+) m6A CDS       24284625//25456834 chr6:7230197-7230198(+) m6A CDS       24284625//24981863 chr6:7230529-7230530(+) m6A CDS       24284625//24981863//22575960 chr6:7230586-7230587(+) m6A CDS       24284625//24981863//22575960 chr6:7230613-7230614(+) m6A CDS       24284625//25456834//24981863//22575960 chr6:7230790-7230791(+) m6A CDS       24284625//25456834//24981863//22575960 chr6:7230871-7230872(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7230923-7230924(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7231015-7231016(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7231033-7231034(+) m6A 5'UTR//CDS       24284625//25456834//24981863//22575960//22608085 chr6:7231078-7231079(+) m6A 5'UTR//CDS       24284625//25456834//24981863//22575960//22608085 chr6:7231156-7231157(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr6:7231171-7231172(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr6:7231337-7231338(+) m6A CDS       24284625 chr6:7231581-7231582(+) m6A CDS       24284625//24981863 chr6:7231594-7231595(+) m6A CDS       24284625//24981863 chr6:7231636-7231637(+) m6A CDS       24284625//24981863//22575960 chr6:7231843-7231844(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr6:7231849-7231850(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr6:7231897-7231898(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr6:7231926-7231927(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7231936-7231937(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7232017-7232018(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7232041-7232042(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr6:7240677-7240678(+) m6A CDS//intron       24284625//25456834//24981863//22575960 chr6:7240749-7240750(+) m6A CDS//intron       24284625 chr6:7246676-7246677(+) m6A CDS//intron       24284625//25456834//24981863//22575960 chr6:7246704-7246705(+) m6A CDS//intron       24284625//25456834//24981863//22575960 chr6:7246719-7246720(+) m6A CDS//intron       24284625//25456834//24981863//22575960 chr6:7246932-7246933(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7246938-7246939(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7246959-7246960(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7247167-7247168(+) m6A CDS//intron       24284625//24209618//25456834//27371828//27773536//22575960//22608085 chr6:7247189-7247190(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr6:7247329-7247330(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828 chr6:7247336-7247337(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22608085 chr6:7247370-7247371(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr6:7247381-7247382(+) m1A CDS//intron       26863196 chr6:7247424-7247425(+) m6A CDS//intron       24284625//25456834//24981863//22575960 chr6:7248766-7248767(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr6:7248778-7248779(+) m6A CDS       24284625//25456834//24981863//27371828//22575960//22608085 chr6:7248843-7248844(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr6:7248857-7248858(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr6:7248887-7248888(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr6:7249019-7249020(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7249115-7249116(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7249225-7249226(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7249336-7249337(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:7249487-7249488(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr6:7249492-7249493(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr6:7249522-7249523(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr6:7249617-7249618(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr6:7249630-7249631(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr6:7249732-7249733(+) m6A 3'UTR       24981863//22608085 chr6:7250319-7250320(+) m6A 3'UTR       24981863 chr6:7250760-7250761(+) m6A 3'UTR       24284625 chr6:7250794-7250795(+) m6A 3'UTR       24284625 chr6:7250909-7250910(+) m6A 3'UTR       24284625//24981863 chr6:7250982-7250983(+) m6A 3'UTR       24981863 chr6:7251790-7251791(+) m6A 3'UTR       22608085 chr6:7251806-7251807(+) m6A 3'UTR       22608085 chr6:7251811-7251812(+) m6A 3'UTR       22608085 chr6:7251974-7251975(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr6:7251981-7251982(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr6:7252021-7252022(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr6:7252029-7252030(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr6:7252054-7252055(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr6:7252073-7252074(+) m6A 3'UTR       24981863//27773535//22608085 chr6:7252134-7252135(+) m6A 3'UTR       27773535//22608085 chr6:7252175-7252176(+) m6A 3'UTR       27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-185-5p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Plasma     29130611 Exosome Primary dendritic cells|T cell line (J77)     21505438 Exosome Breast milk     22211110 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Serum     25135963 Exosome Blood|Tongue tissue     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	RREB1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-185-5p	7-Epi-10-deacetylbaccatin III 9872117 Drug sensitive Midostaurin 9829523 Drug resistant Tiotixene 941651 Drug sensitive Acridine Yellow G 8672 Drug resistant 1,9-Pyrazoloanthrone 8515 Drug resistant Pingyangmycin 84046 Drug resistant Tanakan 83818 Drug sensitive 2,4,6-Tris(2-pyridyl)-s-triazine 77258 Drug sensitive Secalonic acid D 73431 Drug sensitive Coptisine chloride 72321 Drug sensitive 7-Hydroxystaurosporine 72271 Drug resistant Anaxirone 71218 Drug resistant Dihydroxydiphenyl-pyridyl methane 69046 Drug resistant Mevastatin 64715 Drug resistant Everolimus 6442177 Drug resistant Primaquine phosphate 6135 Drug sensitive 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive 8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive Thiopyrimidine-CH3 5473238 Drug sensitive Iejimalide A. 5473233 Drug sensitive 11-Cyanomethylen-11H-indolo[1,2-a]indazole 5472501 Drug resistant 6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive Bleomycin 5460769 Drug resistant Herveline O 5459269 Drug sensitive [2-[2-[(1R,2S)-2-[[6-Amino-2-[1-[(2S)-2,3-diamino-3-oxopropyl]-4-oxoazetidin-2-yl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4S)-3-hydroxy-5-[[(2S,3R)-3-hydroxy-1-[2-[4-[4-[2-(2-hydroxypropylamino)ethylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate 5458321 Drug resistant Melampodin B acetate 5359212 Drug sensitive 5-Methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 Drug sensitive Lovastatin 53232 Drug resistant Cytochalasin B 5311281 Drug resistant Herbimycin 5311102 Drug sensitive 5-Fluoro-2'-deoxycytidine 515328 Drug resistant Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498558 Drug sensitive Staurosporine, 98% 49831000 Drug resistant 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 4713 Drug sensitive Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive 3-3'-(1H-Pyrazole-3,5-diyl)bis(1-methyl-1H-indole) 44433919 Drug resistant 4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine 44397453 Drug resistant 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Bleomycin-BAPP 431594 Drug resistant Bleomycin A5, sulfate 422920 Drug resistant Aminopyrimidine-CH3 406278 Drug sensitive 1H-Naphth[2,3-d]imidazole, 2-[(4-chlorophenyl)methyl]- 405626 Drug resistant Purpureagitosid 401298 Drug resistant Trapoxin B 395803 Drug sensitive 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant 2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive 2-(3-Chloropropyloxy)naphthazarin 378771 Drug sensitive 5,8-Dihydroxy-2-(4-(2-pyridinyl)-1-piperazinyl)naphthoquinone 376947 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant 2,3-Bis(dodecanoyloxy)propylarsonic acid 375754 Drug sensitive Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant 1-(4-Methoxy-2-methylphenyl)naphtho[1,2-c]furan-3(1H)-one 369148 Drug sensitive 3,8,13,18,23-Pentaazapentacosane 368998 Drug sensitive 2,7-Dicyanoxanthone 363841 Drug sensitive Girolline 362388 Drug resistant 1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)- 362170 Drug sensitive 7alpha-Acetoxyroylenane 362048 Drug sensitive Thiosangivamycin 3580213 Drug sensitive Imidazole, 1-(4-chlorophenyl)-4-(4-nitrophenyl)- 355940 Drug resistant 2,3-Dimethylbenzo[g]quinoxaline-5,10-dione 353644 Drug sensitive 1,4-Diaminoanthraquinone 31420 Drug resistant Clomifene citrate 3033832 Drug sensitive SMA-491 (free base of NSC D742838) 302576 Drug resistant Gardenin A 261859 Drug resistant Hookerianamide J 25016666 Drug sensitive Hookerianamide K 25016412 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive CID 24197685 24197685 Drug sensitive Antibiotic U 29135 24196291 Drug sensitive 4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive Kinetin riboside 20345 Drug resistant Chonemorphine 165208 Drug sensitive (6R)-1,6,11-Trihydroxy-8-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-3-methyl-5,6-dihydrobenzo[a]anthracene-7,12-dione 15507920 Drug sensitive Ellipticine analog 148569 Drug resistant (2R)-2-Hydroxy-3-[(6R)-11-hydroxy-2-[4-[(6R)-4-hydroxy-2-[1-hydroxy-3-[(6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-methylpropanoic acid 146158002 Drug sensitive Astrazon Orange R 135747272 Drug sensitive [(8Ar)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate 134694047 Drug resistant Methyl (1S,10R,11S,12S)-11-acetyloxy-12-ethyl-4-[(13R,15R,17R)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 133126830 Drug sensitive (2R,4R,6S,7S,12S)-6,7,16-Trihydroxy-18-methoxy-12-methyl-3,13-dioxatricyclo[13.4.0.02,4]nonadeca-1(15),9,16,18-tetraene-8,14-dione 131676399 Drug sensitive 1,4-Bis((2-aminoethyl)amino)-5,8-dihydroxy-9,10-anthraquinone 125982 Drug resistant Pepleo 122804 Drug resistant Cyanoaminopyranopyridine derivatives 11494577 Drug resistant 1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug resistant Uridine, 2'-deoxy-2'-methylene- 11075548 Drug resistant Acetylenedicarboxamide 10971 Drug sensitive Cladospirone bisepoxide 10316810 Drug sensitive Binimetinib 10288191 Drug sensitive (1S,3R,6R,12S,14R,15S,18R,19E,21Z,25R,26S,27R)-6,15-Dihydroxy-18-[(1R)-1-hydroxyethyl]-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione 101307863 Drug sensitive Selumetinib 10127622 Drug sensitive 1,3,6-triphenyl-oxazolo(5,4-d)pyrimidin-2',4(1h,3h)-dion - Drug resistant 1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant 1-naphthalenecarboxamide, n,n'-1,8-(octanediyl)bis- - Drug resistant 6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant 3-peg fudr (peg floxuridine) - Drug resistant 6-aryl alkyl fluoro quinolone derivative - Drug resistant Annamycin Liposomal - Drug resistant antineoplastic-d655481 - Drug resistant Camptothecin Derivative - Drug resistant geldanamycin dimethylglycinate - Drug resistant organosulfur compound - Drug resistant tartrolon a1 - Drug resistant toxin .delta.53l - Drug resistant tp4ek - Drug resistant viridomycin - Drug resistant (z) 3,3',4,5-tetramethoxystilbene - Drug sensitive 1,2-benzo-8-(d,l-alanyl)-3-phenoxazone nitrate salt - Drug sensitive 1-piperidinecarbodithioic acid, antimony complex - Drug sensitive 2-azabicyclo[16.3.1]docosane, geldanamycin deriv. - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug sensitive benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive iodonium, (4-methoxyphenyl)(3-methylphenyl)-, bromide - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive 5-hydroxyamino camptothecin - Drug sensitive antineoplastic-615538 - Drug sensitive dichlorobisoxinatotitanium(iv) - Drug sensitive geldanamycin deriv - Drug sensitive tetra(isobutenyl)antimony bromide - Drug sensitive xenorhabdin 1 - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-185-5p	Formaldehyde 712 Drug interaction    RC00003208 Oxaliplatine 6857599 Drug interaction    RC00003218 Gemcitabine 60750 Drug interaction    RC00003213 Cholesterol 5997 Drug interaction    RC00003211 Eloxatine 5310940 Drug interaction    RC00003217 Decitabine 451668 Drug interaction    RC00003215 5-Fluorouracil 3385 Drug interaction    RC00003210 Doxorubicin 31703 Drug interaction    RC00003212 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00003209 Tamoxifen 2733526 Drug interaction    RC00003216 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00003219 Benzene 241 Drug interaction    RC00003207 Leucovorin 135403648 Drug interaction    RC00003220

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-185-5p	Cisplatin 5702198       27906433 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-185-5p
Interactor2: RREB1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.