Detail Information

Basic Information:


  VIRBase ID:  

HHID00053051

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-126-5p:           TMEM267:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-126-5p TMEM267
miRBase
Accession/Entrez ID		 MIMAT0000444 64417
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C5orf28

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-126-5p
rs1424556578 chr9:136670632    A/T
rs746772073 chr9:136670629    G/C
rs757031753 chr9:136670633    C/T
rs781001989 chr9:136670634    G/A
rs993093735 chr9:136670628    T/C
rs1487240924 chr9:136670616    CATT/C
rs777307469 chr9:136670618    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMEM267
chr5:43448873(-) A-I      intronic
chr5:43450189(-) A-I      intronic
chr5:43450199(-) A-I      intronic
chr5:43450284(-) A-I      intronic
chr5:43450344(-) A-I      intronic
chr5:43451005(-) A-I      intronic
chr5:43448713(-) A-I      intronic
chr5:43455468(-) A-I      intronic
chr5:43455788(-) A-I      intronic
chr5:43455810(-) A-I      intronic
chr5:43456086(-) A-I      intronic
chr5:43456193(-) A-I      intronic
chr5:43458160(-) A-I      intronic
chr5:43458271(-) A-I      intronic
chr5:43458499(-) A-I      intronic
chr5:43448766(-) A-I      intronic
chr5:43480664(-) A-I      intronic
chr5:43480675(-) A-I      intronic
chr5:43480720(-) A-I      intronic
chr5:43481454(-) A-I      intronic
chr5:43481455(-) A-I      intronic
chr5:43467088(-) A-I      intronic
chr5:43467096(-) A-I      intronic
chr5:43467243(-) A-I      intronic
chr5:43456108(-) A-I      intronic
chr5:43470337(-) A-I      intronic
chr5:43470382(-) A-I      intronic
chr5:43470383(-) A-I      intronic
chr5:43477073(-) A-I      intronic
chr5:43477179(-) A-I      intronic
chr5:43477213(-) A-I      intronic
chr5:43481076(-) A-I      intronic
chr5:43481081(-) A-I      intronic
chr5:43481178(-) A-I      intronic
chr5:43481179(-) A-I      intronic
chr5:43448716(-) A-I      intronic
chr5:43448722(-) A-I      intronic
chr5:43448734(-) A-I      intronic
chr5:43448802(-) A-I      intronic
chr5:43448826(-) A-I      intronic
chr5:43448865(-) A-I      intronic
chr5:43477633(-) A-I      intronic
chr5:43480662(-) A-I      intronic
chr5:43455787(-) A-I      intronic
chr5:43448770(-) A-I      intronic
chr5:43448769(-) A-I      intronic
chr5:43455305(-) A-I      intronic
chr5:43448730(-) A-I      intronic
chr5:43447465(-) A-I      intronic
chr5:43447464(-) A-I      intronic
chr5:43447424(-) A-I      intronic
chr5:43447419(-) A-I      intronic
chr5:43447410(-) A-I      intronic
chr5:43447262(-) A-I      intronic
chr5:43447252(-) A-I      intronic
chr5:43447247(-) A-I      intronic
chr5:43447225(-) A-I      intronic
chr5:43448710(-) A-I      intronic
chr5:43447332(-) A-I      intronic
chr5:43455930(-) A-I      intronic
chr5:43473157(-) A-I      intronic
chr5:43481490(-) A-I      intronic
chr5:43451004(-) A-I      intronic
chr5:43477076(-) A-I      intronic
chr5:43481328(-) A-I      intronic
chr5:43456182(-) A-I      intronic
chr5:43480508(-) A-I      intronic
chr5:43470463(-) A-I      intronic
chr5:43473035(-) A-I      intronic
chr5:43456061(-) A-I      intronic
chr5:43466988(-) A-I      intronic
chr5:43448834(-) A-I      intronic
chr5:43477102(-) A-I      intronic
chr5:43467142(-) A-I      intronic
chr5:43448622(-) A-I      intronic
chr5:43450314(-) A-I      intronic
chr5:43455430(-) A-I      intronic
chr5:43480681(-) A-I      intronic
chr5:43477568(-) A-I      intronic
chr5:43450224(-) A-I      intronic
chr5:43451959(-) A-I      intronic
chr5:43477280(-) A-I      intronic
chr5:43481355(-) A-I      intronic
chr5:43481045(-) A-I      intronic
chr5:43480698(-) A-I      intronic
chr5:43455442(-) A-I      intronic
chr5:43480540(-) A-I      intronic
chr5:43480429(-) A-I      intronic
chr5:43450297(-) A-I      intronic
chr5:43467085(-) A-I      intronic
chr5:43473068(-) A-I      intronic
chr5:43455463(-) A-I      intronic
chr5:43477037(-) A-I      intronic
chr5:43447297(-) A-I      intronic
chr5:43481304(-) A-I      intronic
chr5:43455360(-) A-I      intronic
chr5:43477175(-) A-I      intronic
chr5:43481431(-) A-I      intronic
chr5:43481447(-) A-I      intronic
chr5:43451966(-) A-I      intronic
chr5:43477215(-) A-I      intronic
chr5:43456062(-) A-I      intronic
chr5:43455261(-) A-I      intronic
chr5:43455366(-) A-I      intronic
chr5:43455517(-) A-I      intronic
chr5:43481290(-) A-I      intronic
chr5:43481350(-) A-I      intronic
chr5:43481477(-) A-I      intronic
chr5:43455425(-) A-I      intronic
chr5:43458446(-) A-I      intronic
chr5:43455443(-) A-I      intronic
chr5:43448877(-) A-I      intronic
chr5:43481215(-) A-I      intronic
chr5:43451974(-) A-I      intronic
chr5:43481423(-) A-I      intronic
chr5:43455304(-) A-I      intronic
chr5:43450360(-) A-I      intronic
chr5:43455308(-) A-I      intronic
chr5:43481310(-) A-I      intronic
chr5:43451920(-) A-I      intronic
chr5:43481453(-) A-I      intronic

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-126-5p
Exosome Breast milk     22211110
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Blood|B lymphoblastoid cells|Chronic lymphocytic leukemia cells|Endothelial cells|Lymphoma tissue|Mast cells     -
Extracellular vesicle Plasma     32498409
Microvesicle Plasma     19002258
Microvesicle Plasma     23077538
Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
TMEM267
Chromatin K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-126-5p
Estradiol 5757 Drug interaction    RC00003040
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-126-5p
Cytarabine 6253       25759982
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885
Cetuximab -       26107137

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-126-5p
Interactor2: TMEM267

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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