Basic Information:

  VIRBase ID:  

HHID00049162

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-219a-5p:  MIMAT0000276          PIP4K2A:  NM_001330062     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-219a-5p	PIP4K2A
miRBase Accession/Entrez ID	MIMAT0000276	5305
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	PI5P4KA//PIP5K2A//PIP5KII-alpha//PIP5KIIA//PIPK

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-219a-5p	rs1006626271 chr6:33207872    T/G rs532850145 chr6:33207865    A/C rs532850145 chr6:33207865    A/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PIP4K2A	chr10:22948504(-) A-I      intronic chr10:22851948(-) A-I      intronic chr10:22851949(-) A-I      intronic chr10:22835409(-) A-I      intronic chr10:22851950(-) A-I      intronic chr10:22859255(-) A-I      intronic chr10:22978596(-) A-I      intronic chr10:22835433(-) A-I      intronic chr10:22945008(-) A-I      intronic chr10:22945040(-) A-I      intronic chr10:22851221(-) A-I      intronic chr10:22835424(-) A-I      intronic chr10:22835432(-) A-I      intronic chr10:22887082(-) A-I      intronic chr10:22883457(-) A-I      intronic chr10:22948625(-) A-I      intronic chr10:22883408(-) A-I      intronic chr10:22883397(-) A-I      intronic chr10:22883390(-) A-I      intronic chr10:22887163(-) A-I      intronic chr10:22986483(-) A-I      intronic chr10:22948528(-) A-I      intronic chr10:22948542(-) A-I      intronic chr10:22835417(-) A-I      intronic chr10:22835466(-) A-I      intronic chr10:22948543(-) A-I      intronic chr10:22948536(-) A-I      intronic chr10:22948535(-) A-I      intronic chr10:22851963(-) A-I      intronic chr10:22835461(-) A-I      intronic chr10:22851877(-) A-I      intronic chr10:22851944(-) A-I      intronic chr10:22996040(-) A-I      intronic chr10:22997876(-) A-I      intronic chr10:22851426(-) A-I      intronic chr10:22959213(-) A-I      intronic chr10:22883430(-) A-I      intronic chr10:22835500(-) A-I      intronic chr10:22997884(-) A-I      intronic chr10:22835499(-) A-I      intronic chr10:22887036(-) A-I      intronic chr10:22850732(-) A-I      intronic chr10:22835413(-) A-I      intronic chr10:22835403(-) A-I      intronic chr10:22997926(-) A-I      intronic chr10:22997959(-) A-I      intronic chr10:22851421(-) A-I      intronic chr10:22942009(-) A-I      intronic chr10:22850656(-) A-I      intronic chr10:22939282(-) A-I      intronic chr10:22941114(-) A-I      intronic chr10:22883543(-) A-I      intronic chr10:22997804(-) A-I      intronic chr10:22941180(-) A-I      intronic chr10:22954446(-) A-I      intronic chr10:22970573(-) A-I      intronic chr10:22850648(-) A-I      intronic chr10:22934283(-) A-I      intronic chr10:22977449(-) A-I      intronic chr10:22995994(-) A-I      intronic chr10:22884577(-) A-I      intronic chr10:22950354(-) A-I      intronic chr10:22956977(-) A-I      intronic chr10:22986544(-) A-I      intronic chr10:22850567(-) A-I      intronic chr10:22941856(-) A-I      intronic chr10:22948689(-) A-I      intronic chr10:22941801(-) A-I      intronic chr10:22934392(-) A-I      intronic chr10:22887217(-) A-I      intronic chr10:22851432(-) A-I      intronic chr10:22986542(-) A-I      intronic chr10:22835612(-) A-I      intronic chr10:22900211(-) A-I      intronic chr10:22986428(-) A-I      intronic chr10:22884578(-) A-I      intronic chr10:22950571(-) A-I      intronic chr10:22986400(-) A-I      intronic chr10:22934303(-) A-I      intronic chr10:22950321(-) A-I      intronic chr10:22891753(-) A-I      intronic chr10:22887115(-) A-I      intronic chr10:22887131(-) A-I      intronic chr10:22957152(-) A-I      intronic chr10:22837757(-) A-I      intronic chr10:22941985(-) A-I      intronic chr10:22941936(-) A-I      intronic chr10:22986372(-) A-I      intronic chr10:22977578(-) A-I      intronic chr10:22942746(-) A-I      intronic chr10:22851353(-) A-I      intronic chr10:22941906(-) A-I      intronic chr10:22942789(-) A-I      intronic chr10:22851288(-) A-I      intronic chr10:22900267(-) A-I      intronic chr10:22941831(-) A-I      intronic chr10:22941815(-) A-I      intronic chr10:22941306(-) A-I      intronic chr10:22887237(-) A-I      intronic chr10:22941196(-) A-I      intronic chr10:22959111(-) A-I      intronic chr10:22908530(-) A-I      intronic chr10:22997917(-) A-I      intronic chr10:22887240(-) A-I      intronic chr10:22851369(-) A-I      intronic chr10:22897566(-) A-I      intronic chr10:22884546(-) A-I      intronic chr10:22941296(-) A-I      intronic chr10:22883601(-) A-I      intronic chr10:22851343(-) A-I      intronic chr10:22897706(-) A-I      intronic chr10:22837827(-) A-I      intronic chr10:22941190(-) A-I      intronic chr10:22904276(-) A-I      intronic chr10:22904284(-) A-I      intronic chr10:22934418(-) A-I      intronic chr10:22934680(-) A-I      intronic chr10:22850786(-) A-I      intronic chr10:22941077(-) A-I      intronic chr10:22941163(-) A-I      intronic chr10:22850713(-) A-I      intronic chr10:22986603(-) A-I      intronic chr10:22963840(-) A-I      intronic chr10:22977545(-) A-I      intronic chr10:22884494(-) A-I      intronic chr10:22884523(-) A-I      intronic chr10:22975690(-) A-I      intronic chr10:22957160(-) A-I      intronic chr10:22884468(-) A-I      intronic chr10:22950564(-) A-I      intronic chr10:22949231(-) A-I      intronic chr10:22963865(-) A-I      intronic chr10:22948613(-) A-I      intronic chr10:22851296(-) A-I      intronic chr10:22950410(-) A-I      intronic chr10:22948661(-) A-I      intronic chr10:22954434(-) A-I      intronic chr10:22975482(-) A-I      intronic chr10:22851284(-) A-I      intronic chr10:22887104(-) A-I      intronic chr10:22949183(-) A-I      intronic chr10:22949208(-) A-I      intronic chr10:22949234(-) A-I      intronic chr10:22950316(-) A-I      intronic chr10:22884610(-) A-I      intronic chr10:22883552(-) A-I      intronic chr10:22850562(-) A-I      intronic chr10:22941243(-) A-I      intronic chr10:22950388(-) A-I      intronic chr10:22887241(-) A-I      intronic chr10:22883518(-) A-I      intronic chr10:22975504(-) A-I      intronic chr10:22950493(-) A-I      intronic chr10:22883449(-) A-I      intronic chr10:22950519(-) A-I      intronic chr10:22975490(-) A-I      intronic chr10:22950568(-) A-I      intronic chr10:22883427(-) A-I      intronic chr10:22954581(-) A-I      intronic chr10:22887095(-) A-I      intronic chr10:22964332(-) A-I      intronic chr10:22954595(-) A-I      intronic chr10:22954608(-) A-I      intronic chr10:22883422(-) A-I      intronic chr10:22883417(-) A-I      intronic chr10:22883393(-) A-I      intronic chr10:22954609(-) A-I      intronic chr10:22883385(-) A-I      intronic chr10:22956978(-) A-I      intronic chr10:22941911(-) A-I      intronic chr10:22941253(-) A-I      intronic chr10:22957005(-) A-I      intronic chr10:22957029(-) A-I      intronic chr10:22868738(-) A-I      intronic chr10:22850681(-) A-I      intronic chr10:22941274(-) A-I      intronic chr10:22959125(-) A-I      intronic chr10:22851452(-) A-I      intronic chr10:22975503(-) A-I      intronic chr10:22949386(-) A-I      intronic chr10:22996009(-) A-I      intronic chr10:22957021(-) A-I      intronic chr10:22835586(-) A-I      intronic chr10:22835573(-) A-I      intronic chr10:22950551(-) A-I      intronic chr10:22837930(-) A-I      intronic chr10:22850768(-) A-I      intronic chr10:22996027(-) A-I      intronic chr10:22954606(-) A-I      intronic chr10:22869331(-) A-I      intronic chr10:22950492(-) A-I      intronic chr10:22986572(-) A-I      intronic chr10:22950565(-) A-I      intronic chr10:22887084(-) A-I      intronic chr10:22950559(-) A-I      intronic chr10:22941322(-) A-I      intronic chr10:22948337(-) A-I      intronic chr10:22925391(-) A-I      intronic chr10:22970598(-) A-I      intronic chr10:22883442(-) A-I      intronic chr10:22974598(-) A-I      intronic chr10:22868781(-) A-I      intronic chr10:22950383(-) A-I      intronic chr10:22942756(-) A-I      intronic chr10:22883519(-) A-I      intronic chr10:22883492(-) A-I      intronic chr10:22949317(-) A-I      intronic chr10:22954509(-) A-I      intronic chr10:22949155(-) A-I      intronic chr10:22837901(-) A-I      intronic chr10:22992286(-) A-I      intronic chr10:22934254(-) A-I      intronic chr10:22934722(-) A-I      intronic chr10:22975672(-) A-I      intronic chr10:22986595(-) A-I      intronic chr10:22941329(-) A-I      intronic chr10:22992226(-) A-I      intronic chr10:22934353(-) A-I      intronic chr10:22883489(-) A-I      intronic chr10:22977619(-) A-I      intronic chr10:22963686(-) A-I      intronic chr10:22950449(-) A-I      intronic chr10:22934754(-) A-I      intronic chr10:22974582(-) A-I      intronic chr10:22934253(-) A-I      intronic chr10:22835505(-) A-I      intronic chr10:22986573(-) A-I      intronic chr10:22883453(-) A-I      intronic chr10:22957032(-) A-I      intronic chr10:22934412(-) A-I      intronic chr10:22954482(-) A-I      intronic chr10:22949149(-) A-I      intronic chr10:22948654(-) A-I      intronic chr10:22934258(-) A-I      intronic chr10:22837861(-) A-I      intronic chr10:22934930(-) A-I      intronic chr10:22939293(-) A-I      intronic chr10:22891752(-) A-I      intronic chr10:22934282(-) A-I      intronic chr10:22835555(-) A-I      intronic chr10:22948615(-) A-I      intronic chr10:22964335(-) A-I      intronic chr10:22975674(-) A-I      intronic chr10:22850601(-) A-I      intronic chr10:22942617(-) A-I      intronic chr10:22835469(-) A-I      intronic chr10:22950491(-) A-I      intronic chr10:22870945(-) A-I      intronic chr10:22974531(-) A-I      intronic chr10:22975471(-) A-I      intronic chr10:22997850(-) A-I      intronic chr10:22977546(-) A-I      intronic chr10:22975630(-) A-I      intronic chr10:22954502(-) A-I      intronic chr10:22850636(-) A-I      intronic chr10:22941109(-) A-I      intronic chr10:22941218(-) A-I      intronic chr10:22950538(-) A-I      intronic chr10:22835455(-) A-I      intronic chr10:22864785(-) A-I      intronic chr10:22875624(-) A-I      intronic chr10:22934272(-) A-I      intronic chr10:22883481(-) A-I      intronic chr10:22948374(-) A-I      intronic chr10:22941928(-) A-I      intronic chr10:22941835(-) A-I      intronic chr10:22884574(-) A-I      intronic chr10:22883580(-) A-I      intronic chr10:22957063(-) A-I      intronic chr10:22887243(-) A-I      intronic chr10:22850577(-) A-I      intronic chr10:22977479(-) A-I      intronic chr10:22851354(-) A-I      intronic chr10:22883440(-) A-I      intronic chr10:22948339(-) A-I      intronic chr10:22959199(-) A-I      intronic chr10:22850699(-) A-I      intronic chr10:22941982(-) A-I      intronic chr10:22850540(-) A-I      intronic chr10:22837871(-) A-I      intronic chr10:22850661(-) A-I      intronic chr10:22891117(-) A-I      intronic chr10:22964517(-) A-I      intronic chr10:22883529(-) A-I      intronic chr10:22850718(-) A-I      intronic chr10:22998006(-) A-I      intronic chr10:22850767(-) A-I      intronic chr10:22835543(-) A-I      intronic chr10:22986619(-) A-I      intronic chr10:22995991(-) A-I      intronic chr10:22956997(-) A-I      intronic chr10:22883409(-) A-I      intronic chr10:22941184(-) A-I      intronic chr10:22850675(-) A-I      intronic chr10:22934240(-) A-I      intronic chr10:22949292(-) A-I      intronic chr10:22887107(-) A-I      intronic chr10:22850620(-) A-I      intronic chr10:22964367(-) A-I      intronic chr10:22997945(-) A-I      intronic chr10:22954404(-) A-I      intronic chr10:22949291(-) A-I      intronic chr10:22941971(-) A-I      intronic chr10:22949217(-) A-I      intronic chr10:22948655(-) A-I      intronic chr10:22942013(-) A-I      intronic chr10:22977590(-) A-I      intronic chr10:22883392(-) A-I      intronic chr10:22934399(-) A-I      intronic chr10:22835452(-) A-I      intronic chr10:22941143(-) A-I      intronic chr10:22950378(-) A-I      intronic chr10:22949288(-) A-I      intronic chr10:22976658(-) A-I      intronic chr10:22957080(-) A-I      intronic chr10:22975633(-) A-I      intronic chr10:22835714(-) A-I      intronic chr10:22843941(-) A-I      intronic chr10:22944981(-) A-I      intronic chr10:22842379(-) A-I      intronic chr10:22944971(-) A-I      intronic chr10:22825581(-) A-I      3'UTR chr10:22964415(-) A-I      intronic chr10:22865871(-) A-I      intronic chr10:22997939(-) A-I      intronic chr10:22948478(-) A-I      intronic chr10:22859884(-) A-I      intronic chr10:22978552(-) A-I      intronic chr10:22975545(-) A-I      intronic chr10:22899264(-) A-I      intronic chr10:22853666(-) A-I      intronic chr10:22976623(-) A-I      intronic chr10:22853751(-) A-I      intronic chr10:22859928(-) A-I      intronic chr10:22851985(-) A-I      intronic chr10:22978553(-) A-I      intronic chr10:22976622(-) A-I      intronic chr10:22883602(-) A-I      intronic chr10:22859258(-) A-I      intronic chr10:22851945(-) A-I      intronic chr10:22944943(-) A-I      intronic chr10:22948446(-) A-I      intronic chr10:22984595(-) A-I      intronic chr10:22944958(-) A-I      intronic chr10:22858989(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PIP4K2A	chr10:22859258(-) A-I intron -    22327324 chr10:22825581(-) A-I exon 3'UTR    21960545 chr10:22976622(-) A-G intron -    22484847 chr10:22976623(-) A-G intron -    22484847 chr10:22976658(-) A-G intron -    22484847 chr10:22978552(-) A-G intron -    22484847 chr10:22978553(-) A-G intron -    22484847 chr10:22984595(-) A-G intron -    22484847 chr10:22851288(-) A-G intron -    22484847 chr10:22950378(-) A-G intron -    22484847 chr10:22950410(-) A-G intron -    22484847 chr10:22950491(-) A-G intron -    22484847 chr10:22950492(-) A-G intron -    22484847 chr10:22950551(-) A-G intron -    22484847 chr10:22950564(-) A-G intron -    22484847 chr10:22950565(-) A-G intron -    22484847 chr10:22859258(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PIP4K2A	chr10:22824145-22824146(-) m6A 3'UTR       - chr10:22824159-22824160(-) m6A 3'UTR       - chr10:22824444-22824445(-) m6A 3'UTR       27773535 chr10:22824513-22824514(-) m6A 3'UTR       27773535 chr10:22824521-22824522(-) m6A 3'UTR       27773535 chr10:22824559-22824560(-) m6A 3'UTR       27773535 chr10:22824573-22824574(-) m6A 3'UTR       27773535 chr10:22825416-22825417(-) m6A 3'UTR       24284625//27773535 chr10:22825519-22825520(-) m6A 3'UTR       24284625//24981863//26404942//27773535 chr10:22825556-22825557(-) m6A 3'UTR       24981863//26404942//27773535 chr10:22825624-22825625(-) m6A 3'UTR       24981863//26404942//27773535 chr10:22825678-22825679(-) m6A 3'UTR       24981863//26404942//27773535 chr10:22825745-22825746(-) m6A 3'UTR       24981863//27773535 chr10:22825802-22825803(-) m6A 3'UTR       24981863//27773535 chr10:22825838-22825839(-) m6A 3'UTR//exon       27773535 chr10:22826020-22826021(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22826052-22826053(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22826057-22826058(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22826089-22826090(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22826100-22826101(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22826106-22826107(-) m6A 3'UTR//exon       25456834 chr10:22826110-22826111(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22826154-22826155(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22826177-22826178(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22826184-22826185(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:22828434-22828435(-) m6A exon//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr10:22828459-22828460(-) m6A exon//intron       24284625//24981863//28052920//27773535//27371828//22608085 chr10:22828905-22828906(-) m6A CDS       24284625//24209618//27773535 chr10:22828913-22828914(-) m6A CDS       24284625//24209618//27773535 chr10:22830764-22830765(-) m6A CDS       24284625//24209618//27773535//27371828 chr10:22830803-22830804(-) m6A CDS       24209618//27773535//27371828 chr10:22830834-22830835(-) m6A CDS       24209618//24981863//27773535//27371828 chr10:22830907-22830908(-) m6A CDS       24981863//27773535//27371828 chr10:22830950-22830951(-) m6A CDS       24981863//27773535//27371828 chr10:22839605-22839606(-) m6A CDS       24981863//27773535 chr10:22839692-22839693(-) m6A CDS       27773535 chr10:22856494-22856495(-) m6A exon//intron       27773535 chr10:22856515-22856516(-) m6A exon//intron       27773535 chr10:22856544-22856545(-) m6A exon//intron       27773535 chr10:22856576-22856577(-) m6A exon//intron       27773535 chr10:22896946-22896947(-) m6A CDS//exon       27773535 chr10:22898566-22898567(-) m6A CDS//exon       27773535 chr10:22898637-22898638(-) m6A 5'UTR//CDS//exon       27773535 chr10:22930975-22930976(-) m6A exon//intron       27773535 chr10:22935188-22935189(-) m6A exon//intron       27773535 chr10:23003194-23003195(-) m1A CDS       26863196//26863410 chr10:23003203-23003204(-) m6A CDS       24209618//27371828 chr10:23003209-23003210(-) m6A CDS       24209618//27371828 chr10:23003269-23003270(-) m6A 5'UTR       24209618//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-219a-5p	Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Exosome Brain tissue     23382797 Exosome Blood     - Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
	PIP4K2A	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-219a-5p	Sensorad 99342 Drug sensitive Curcumin 969516 Drug sensitive Thiocyanic acid, 1H-purin-6-yl ester 96185 Drug sensitive 5-Iodo-8-quinolinol 96111 Drug sensitive 5-Fluorouridine 9427 Drug sensitive 4-(2-Pyridylazo)-N,N-dimethylaniline 81528 Drug sensitive Edatrexate 6917908 Drug sensitive Thioinosine 676166 Drug sensitive Dihydroartemisinyl ether, stereoisomer of NSC-685989 6712439 Drug sensitive Antineoplastic-301477 6711219 Drug sensitive Rufigallol 65737 Drug sensitive N-(6-Phenyl-1H-indazol-3-yl)cyclopropanecarboxamide 6539593 Drug sensitive Thioguanosine 6419960 Drug sensitive Verrucarin A 6326658 Drug sensitive Cytarabine 6253 Drug sensitive Artelasticin 5471311 Drug sensitive [(1H-Benzimidazole-2-yl)dithio]-9H-purine 54613148 Drug sensitive 21-[2-(N,3,5(10),17(20)-Tetraen-3-ol citrate salt 54612678 Drug sensitive 2,10-Anthrylenedimethylene)-bis[2-thiopseudourea] dihydrochloride 54603799 Drug sensitive Aspiculamycin hcl 54600418 Drug resistant 4-Cycloheptyl-N-(1-pyridin-2-ylethylideneamino)piperazine-1-carbothioamide 5351332 Drug sensitive Hydroxy AT 125 5351254 Drug sensitive Reumycin 5351216 Drug resistant Spermine hydrochloride 5351186 Drug sensitive Vorinostat 5311 Drug sensitive 6-Methoxy-7-(2lambda(5)-1,2-triazadienyl)-5,8-quinolinedione 494043 Drug sensitive Mycophenolic acid 446541 Drug sensitive [(1R,2S,3S,5R,6R,8S,10E,12R,13S,15R,16S,17R,18S)-18-Benzyl-6-hydroxy-6,8,15,16-tetramethyl-7,20-dioxo-4,14-dioxa-19-azapentacyclo[10.8.0.01,17.03,5.013,15]icos-10-en-2-yl] acetate 44559501 Drug sensitive 5-(Chloromethyl)quinolin-8-ol 416881 Drug sensitive Asimicinone 393461 Drug sensitive N-Hydroxy-N-methylpropanethioamide 371713 Drug sensitive 2,7-Dicyanoxanthone 363841 Drug resistant Thiosangivamycin 3580213 Drug sensitive Nordracorubin 341882 Drug sensitive Buellolide 337850 Drug sensitive Rocaglamide 331783 Drug sensitive Rustaiyan A 324967 Drug sensitive 6-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]-7H-purin-2-amine 3246652 Drug sensitive Ellipticine 3213 Drug sensitive 2,2',3,3'-Tetrahydroxy-1,1'-binaphthyl 316673 Drug sensitive 2-Chloro-3-(dodecylsulfanyl)-5,6-dimethoxycyclohexa-2,5-diene-1,4-dione 312122 Drug sensitive Stannane, trimethyl[(4-morpholinylthioxomethyl)thio]- 300936 Drug sensitive 2-Hydroxy-4-((2,4,6-triamino-5-pyrimidinyl)diazenyl)phenylarsonic acid 272658 Drug sensitive D-Arabinose, 5-O-trityl-tribenzoate 265952 Drug sensitive 4-Benzoyl-3H-benzo[f]quinoline-3-carbonitrile 262649 Drug sensitive Haterumalide NA methyl esters 24204452 Drug resistant cis-3-O-p-Hydroxycinnamoyl ursolic acid 24203732 Drug sensitive 1-(3-Bromo-phenyl)-3-(pyridin-2-ylsulfanyl)-propenone 24203485 Drug sensitive 6-(Hexynyl)-2(2H)-pyranone 24203137 Drug sensitive Antibiotic U 29135 24196291 Drug sensitive Mepacrine mustard dihydrochloride 24180972 Drug sensitive 8-Hydroxyquinoline 1923 Drug sensitive Sudan II 18386 Drug sensitive 8-Chloro-cyclicamp 17856967 Drug sensitive Dihydroartemisinin (mixture of alpha and beta isomers) 16399850 Drug sensitive Antineoplastic-633273 15954131 Drug sensitive [(1R,2R,4R,6E,9R,10S)-2,7-Dimethyl-5,8,14-trioxo-10-prop-1-en-2-yl-15-oxatricyclo[11.2.1.02,4]hexadeca-6,13(16)-dien-9-yl] acetate 15384977 Drug sensitive Ellipticine analog 148569 Drug sensitive 8-Chloroadenosine 147569 Drug sensitive (1S,3S,6'R,7S,15R,16R,17S,18R,19R,20S,21R,22E,26S,28R,30R)-17-[(2S,5S,6S)-5-(Dimethylamino)-6-methyloxan-2-yl]oxy-3,15,16,18,20,21-hexahydroxy-6'-[(2R)-2-hydroxybutyl]-5,5,15,19,21,30-hexamethylspiro[4,25,29-trioxatricyclo[24.3.1.03,7]triaconta-8,22-diene-28,2'-oxane]-24-one 139583769 Drug sensitive (1R,6R,13S)-16,17-Dimethoxy-6-propan-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one 13845974 Drug sensitive 12-Iminodaunorubicin hcl 135539784 Drug sensitive 7-Nitro-1,2,4-benzotriazin-3-amine 1,4-dioxide 135427573 Drug sensitive Inosine dialdehyde 135400916 Drug sensitive Terpentecin 127568 Drug sensitive Piperidinium europium benzoyl trifluoroacetonate 11979537 Drug sensitive 15,16-Dihydrocuracin A 101683509 Drug sensitive (3S,6S)-1,4-Dimethyl-3,6-bis[(2R)-3,3,3-trichloro-2-methylpropyl]piperazine-2,5-dione 101425118 Drug sensitive Chimaphilin 101211 Drug sensitive Tocladesine 100299 Drug sensitive (1R,2E,6R,10E,11aS,13S,14aR)-1,13-dihydroxy-6-(2-methoxyethyl)-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one - Drug resistant 2,3-dihydro-1,2-syn-3-[phenylseleno]brefeldin a - Drug resistant (Z)-5-chloro-3-((1-(3,5-dimethoxyphenyl)-9H-pyrido[3,4-b]indol-3-yl)methylene)indolin-2-one - Drug sensitive 1,2,3-thiadiazole, 5-[(4-chlorophenyl)sulfonyl]-4-phenyl- - Drug sensitive 1,8-octanediamine, n,n'-di-9-acridinyl- (9ci) - Drug sensitive 1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive 1h-benzo[a]carbazole-1,4(11h)-dione, 11-phenyl- - Drug sensitive 2h-naphtho[1,2-b]pyran-2-one, 9-hydroxy-4-phenyl- - Drug sensitive 6-hydroxymethyl-1,3,8-trihydroxyanthraquinone - Drug sensitive 7-benzyl-5,7-dihydro-4h-isoxazolo[5,4-e]isoindole - Drug sensitive 9h-purine, 2-amino-6-(2,4-dichlorobenzylthio)-9-isobutyl- - Drug sensitive 9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 2-methyl- - Drug sensitive aceanthryleno[1,2-b]quinoxaline, 12-nitro- - Drug sensitive benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive bersaldegenin 1,3,5-orthoacetate - Drug sensitive cyclohexanone, 2,6-bis(piperidinomethyl)- - Drug sensitive ethyl-2,3-oxido-(5-bromo-2-methoxyphenyl)propionate - Drug sensitive guanosine, 6-thio-, platinum complex (9ci) - Drug sensitive l-cysteine, s-[(4-methylphenyl)diphenylmethyl]- (9ci) - Drug sensitive n,n'-di-9-acridinyl-1,6-hexanediamine - Drug sensitive sulfide, 2,4-dinitrophenyl 2-nitro-p-tolyl - Drug sensitive thiourea, n-(1-ethylpropyl)-n'-[(2-thienyl)thioxomethyl]- - Drug sensitive tris(1,3-diphenylpropane-1,3-dionata)gallium(iii) - Drug sensitive 10-hydroxy-scandine - Drug sensitive antineoplastic-641297 - Drug sensitive Indenoisoquinoline derivative - Drug sensitive largomycin f-ii - Drug sensitive leucinostatine d - Drug sensitive n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive streptorubrin - Drug sensitive trans-4-{4-[3-(4-chloro-3-trifluoromethyl-phenyl)-ureido]-cyclohexyloxy}-pyridine-2-carboxylic acid methylamide - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-219a-5p	Ethanol 702 Drug interaction    RC00002152 Eloxatine 5310940 Drug interaction    RC00002156 5-Fluorouracil 3385 Drug interaction    RC00002154 Doxorubicin 31703 Drug interaction    RC00002155 Verapamil 2520 Drug interaction    RC00002153

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-219a-5p	Cisplatin 5702198       30999114

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-219a-5p
Interactor2: PIP4K2A

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.