Detail Information

Basic Information:


  VIRBase ID:  

HHID00044900

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:           TMEM170A:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30a-3p TMEM170A
miRBase
Accession/Entrez ID		 MIMAT0000088 124491
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - TMEM170

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30a-3p
rs149150037 chr6:71403567    G/A
rs149150037 chr6:71403567    G/C
rs370184894 chr6:71403566    C/A
rs370184894 chr6:71403566    C/T
rs552541514 chr6:71403558    C/G
rs745605208 chr6:71403563    ATCCG/A
rs746505574 chr6:71403557    G/A
rs746505574 chr6:71403557    G/T
rs746965145 chr6:71403554    GCT/G
rs750918072 chr6:71403564    T/C
rs765735953 chr6:71403560    A/T
rs770865356 chr6:71403559    A/AC
rs776574456 chr6:71403560    A/AAGCTGGAGT
rs368070339 chr6:71403571    G/A
rs769702885 chr6:71403570    TG/T
rs775921090 chr6:71403574    AGCC/A
rs781617967 chr6:71403573    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMEM170A
chr16:75482768(-) A-I      intronic
chr16:75482915(-) A-I      intronic
chr16:75484733(-) A-I      intronic
chr16:75483435(-) A-I      intronic
chr16:75482847(-) A-I      intronic
chr16:75482787(-) A-I      intronic
chr16:75482742(-) A-I      intronic
chr16:75482909(-) A-I      intronic
chr16:75483436(-) A-I      intronic
chr16:75492854(-) A-I      intronic
chr16:75483489(-) A-I      intronic
chr16:75483421(-) A-I      intronic
chr16:75483288(-) A-I      intronic
chr16:75482897(-) A-I      intronic
chr16:75482851(-) A-I      intronic
chr16:75482743(-) A-I      intronic
chr16:75493083(-) A-I      intronic
chr16:75482416(-) A-I      intronic
chr16:75492974(-) A-I      intronic
chr16:75489171(-) A-I      intronic
chr16:75486446(-) A-I      intronic
chr16:75487237(-) A-I      intronic
chr16:75489168(-) A-I      intronic
chr16:75487318(-) A-I      intronic
chr16:75487291(-) A-I      intronic
chr16:75493655(-) A-I      intronic
chr16:75493679(-) A-I      intronic
chr16:75493753(-) A-I      intronic
chr16:75496256(-) A-I      intronic
chr16:75496353(-) A-I      intronic
chr16:75484740(-) A-I      intronic
chr16:75484810(-) A-I      intronic
chr16:75485231(-) A-I      intronic
chr16:75487275(-) A-I      intronic
chr16:75487288(-) A-I      intronic
chr16:75487147(-) A-I      intronic
chr16:75484670(-) A-I      intronic
chr16:75493059(-) A-I      intronic
chr16:75493065(-) A-I      intronic
chr16:75485230(-) A-I      intronic
chr16:75487115(-) A-I      intronic
chr16:75489575(-) A-I      intronic
chr16:75493510(-) A-I      intronic
chr16:75484726(-) A-I      intronic
chr16:75483416(-) A-I      intronic
chr16:75487160(-) A-I      intronic
chr16:75492888(-) A-I      intronic
chr16:75482902(-) A-I      intronic
chr16:75485299(-) A-I      intronic
chr16:75486526(-) A-I      intronic
chr16:75482794(-) A-I      intronic
chr16:75483294(-) A-I      intronic
chr16:75493716(-) A-I      intronic
chr16:75490275(-) A-I      intronic
chr16:75482921(-) A-I      intronic
chr16:75482816(-) A-I      intronic
chr16:75496255(-) A-I      intronic
chr16:75487129(-) A-I      intronic
chr16:75484763(-) A-I      intronic
chr16:75485298(-) A-I      intronic
chr16:75484742(-) A-I      intronic
chr16:75485272(-) A-I      intronic
chr16:75496272(-) A-I      intronic
chr16:75482772(-) A-I      intronic
chr16:75482756(-) A-I      intronic
chr16:75485338(-) A-I      intronic
chr16:75485278(-) A-I      intronic
chr16:75486481(-) A-I      intronic
chr16:75493589(-) A-I      intronic
chr16:75496278(-) A-I      intronic
chr16:75486597(-) A-I      intronic
chr16:75487216(-) A-I      intronic
chr16:75489521(-) A-I      intronic
chr16:75486141(-) A-I      intronic
chr16:75493575(-) A-I      intronic
chr16:75488999(-) A-I      intronic
chr16:75486459(-) A-I      intronic
chr16:75496284(-) A-I      intronic
chr16:75484721(-) A-I      intronic
chr16:75490251(-) A-I      intronic
chr16:75493673(-) A-I      intronic
chr16:75483268(-) A-I      intronic
chr16:75483449(-) A-I      intronic
chr16:75483318(-) A-I      intronic
chr16:75482716(-) A-I      intronic
chr16:75490274(-) A-I      intronic
chr16:75496303(-) A-I      intronic
chr16:75485364(-) A-I      intronic
chr16:75484855(-) A-I      intronic
chr16:75489591(-) A-I      intronic
chr16:75496310(-) A-I      intronic
chr16:75483420(-) A-I      intronic
chr16:75482907(-) A-I      intronic
chr16:75486304(-) A-I      intronic
chr16:75482882(-) A-I      intronic
chr16:75487139(-) A-I      intronic
chr16:75485191(-) A-I      intronic
chr16:75482714(-) A-I      intronic
chr16:75490330(-) A-I      intronic
chr16:75490369(-) A-I      intronic
chr16:75484588(-) A-I      intronic
chr16:75493633(-) A-I      intronic
chr16:75486259(-) A-I      intronic
chr16:75483443(-) A-I      intronic
chr16:75482913(-) A-I      intronic
chr16:75484755(-) A-I      intronic
chr16:75485325(-) A-I      intronic
chr16:75496224(-) A-I      intronic
chr16:75483373(-) A-I      intronic
chr16:75482793(-) A-I      intronic
chr16:75484793(-) A-I      intronic
chr16:75483512(-) A-I      intronic
chr16:75482540(-) A-I      intronic
chr16:75487166(-) A-I      intronic
chr16:75484833(-) A-I      intronic
chr16:75489088(-) A-I      intronic
chr16:75485202(-) A-I      intronic
chr16:75484729(-) A-I      intronic
chr16:75485203(-) A-I      intronic
chr16:75486460(-) A-I      intronic
chr16:75484759(-) A-I      intronic
chr16:75482843(-) A-I      intronic
chr16:75487220(-) A-I      intronic
chr16:75493081(-) A-I      intronic
chr16:75489581(-) A-I      intronic
chr16:75484600(-) A-I      intronic
chr16:75487135(-) A-I      intronic
chr16:75489091(-) A-I      intronic
chr16:75483450(-) A-I      intronic
chr16:75484739(-) A-I      intronic
chr16:75489565(-) A-I      intronic
chr16:75484832(-) A-I      intronic
chr16:75483434(-) A-I      intronic
chr16:75496223(-) A-I      intronic
chr16:75483351(-) A-I      intronic
chr16:75487114(-) A-I      intronic
chr16:75486594(-) A-I      intronic
chr16:75484792(-) A-I      intronic
chr16:75489529(-) A-I      intronic
chr16:75484734(-) A-I      intronic
chr16:75482703(-) A-I      intronic
chr16:75482495(-) A-I      intronic
chr16:75485323(-) A-I      intronic
chr16:75490230(-) A-I      intronic
chr16:75492920(-) A-I      intronic
chr16:75486588(-) A-I      intronic
chr16:75482715(-) A-I      intronic
chr16:75489066(-) A-I      intronic
chr16:75483490(-) A-I      intronic
chr16:75492897(-) A-I      intronic
chr16:75482835(-) A-I      intronic
chr16:75482837(-) A-I      intronic
chr16:75483328(-) A-I      intronic
chr16:75483472(-) A-I      intronic
chr16:75482850(-) A-I      intronic
chr16:75484783(-) A-I      intronic
chr16:75482757(-) A-I      intronic
chr16:75487232(-) A-I      intronic
chr16:75482498(-) A-I      intronic
chr16:75493708(-) A-I      intronic
chr16:75485431(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TMEM170A
chr16:75482843(-) A-I intron -    22327324
chr16:75482757(-) A-G intron -    22484847
chr16:75482793(-) A-G intron -    22484847
chr16:75482816(-) A-G intron -    22484847
chr16:75482843(-) A-G intron -    22484847
chr16:75482913(-) A-G intron -    22484847
chr16:75482921(-) A-G intron -    22484847
chr16:75483294(-) A-G intron -    22484847
chr16:75484739(-) A-G intron -    22484847
chr16:75484759(-) A-G intron -    22484847
chr16:75484793(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMEM170A
chr16:75479159-75479160(-) m6A 3'UTR       -
chr16:75479186-75479187(-) m6A 3'UTR       -
chr16:75479234-75479235(-) m6A 3'UTR       27773535
chr16:75479259-75479260(-) m6A 3'UTR       -
chr16:75479272-75479273(-) m6A 3'UTR       -
chr16:75479502-75479503(-) m6A 3'UTR//intron       24981863
chr16:75479524-75479525(-) m6A 3'UTR//intron       24981863
chr16:75479529-75479530(-) m6A 3'UTR//intron       24981863
chr16:75481248-75481249(-) m6A 3'UTR       25456834//24981863//27773535//22608085
chr16:75481270-75481271(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr16:75481280-75481281(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr16:75481328-75481329(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr16:75481337-75481338(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr16:75481343-75481344(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr16:75481422-75481423(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr16:75481428-75481429(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr16:75481509-75481510(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//22608085
chr16:75485556-75485557(-) m6A CDS//intron       22608085
chr16:75485591-75485592(-) m6A CDS//intron       24209618//22608085
chr16:75485648-75485649(-) m6A CDS       24209618//24981863//27773535//22608085
chr16:75486553-75486554(-) m6A 5'UTR//intron       24209618
chr16:75498404-75498405(-) m6A CDS//intron       27773535
chr16:75498601-75498602(-) m6A 5'UTR//intron       25456834//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30a-3p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
TMEM170A
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30a-3p
Sorafenib 216239 Drug interaction    RC00000903
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30a-3p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30a-3p
Interactor2: TMEM170A

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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