Basic Information:

  VIRBase ID:  

HHID00044898

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:  MIMAT0000088          SESTD1:  NM_178123     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30a-3p	SESTD1
miRBase Accession/Entrez ID	MIMAT0000088	91404
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	SOLO

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30a-3p	rs149150037 chr6:71403567    G/A rs149150037 chr6:71403567    G/C rs370184894 chr6:71403566    C/A rs370184894 chr6:71403566    C/T rs552541514 chr6:71403558    C/G rs745605208 chr6:71403563    ATCCG/A rs746505574 chr6:71403557    G/A rs746505574 chr6:71403557    G/T rs746965145 chr6:71403554    GCT/G rs750918072 chr6:71403564    T/C rs765735953 chr6:71403560    A/T rs770865356 chr6:71403559    A/AC rs776574456 chr6:71403560    A/AAGCTGGAGT rs368070339 chr6:71403571    G/A rs769702885 chr6:71403570    TG/T rs775921090 chr6:71403574    AGCC/A rs781617967 chr6:71403573    A/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SESTD1	chr2:180025808(-) A-I      intronic chr2:180025811(-) A-I      intronic chr2:180024154(-) A-I      intronic chr2:180112440(-) A-I      intronic chr2:180112290(-) A-I      intronic chr2:180098329(-) A-I      intronic chr2:180098313(-) A-I      intronic chr2:180095105(-) A-I      intronic chr2:180094995(-) A-I      intronic chr2:180094953(-) A-I      intronic chr2:180027716(-) A-I      intronic chr2:180027601(-) A-I      intronic chr2:180024856(-) A-I      intronic chr2:180024851(-) A-I      intronic chr2:180024693(-) A-I      intronic chr2:180020281(-) A-I      intronic chr2:180020260(-) A-I      intronic chr2:180000397(-) A-I      intronic chr2:180000380(-) A-I      intronic chr2:179999851(-) A-I      intronic chr2:179999849(-) A-I      intronic chr2:179999809(-) A-I      intronic chr2:179999783(-) A-I      intronic chr2:179999768(-) A-I      intronic chr2:179999702(-) A-I      intronic chr2:179984893(-) A-I      intronic chr2:180125229(-) A-I      intronic chr2:180125143(-) A-I      intronic chr2:180124151(-) A-I      intronic chr2:180124150(-) A-I      intronic chr2:180124096(-) A-I      intronic chr2:180124055(-) A-I      intronic chr2:180118614(-) A-I      intronic chr2:180125148(-) A-I      intronic chr2:180032586(-) A-I      intronic chr2:180095042(-) A-I      intronic chr2:180124139(-) A-I      intronic chr2:180094987(-) A-I      intronic chr2:180027635(-) A-I      intronic chr2:180027532(-) A-I      intronic chr2:179976652(-) A-I      intronic chr2:180020248(-) A-I      intronic chr2:180109847(-) A-I      intronic chr2:179999854(-) A-I      intronic chr2:180109932(-) A-I      intronic chr2:180124130(-) A-I      intronic chr2:180000246(-) A-I      intronic chr2:180025922(-) A-I      intronic chr2:179999860(-) A-I      intronic chr2:180112442(-) A-I      intronic chr2:179976611(-) A-I      intronic chr2:180000385(-) A-I      intronic chr2:180019838(-) A-I      intronic chr2:180027464(-) A-I      intronic chr2:180000466(-) A-I      intronic chr2:180095027(-) A-I      intronic chr2:180124069(-) A-I      intronic chr2:180098318(-) A-I      intronic chr2:180094965(-) A-I      intronic chr2:180025764(-) A-I      intronic chr2:180025799(-) A-I      intronic chr2:180112386(-) A-I      intronic chr2:180000474(-) A-I      intronic chr2:180019737(-) A-I      intronic chr2:180095136(-) A-I      intronic chr2:180000396(-) A-I      intronic chr2:180025915(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SESTD1	chr2:179999854(-) A-G intron -    22484847 chr2:179999860(-) A-G intron -    22484847 chr2:180000385(-) A-G intron -    22484847 chr2:180000386(-) A-G intron -    22484847 chr2:180000396(-) A-G intron -    22484847 chr2:180027606(-) A-G intron -    22484847 chr2:180124139(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SESTD1	chr2:179966476-179966477(-) m6A 3'UTR       27773535 chr2:179966487-179966488(-) m6A 3'UTR       27773535 chr2:179966560-179966561(-) m6A 3'UTR       27773535 chr2:179967559-179967560(-) m6A 3'UTR       27773535 chr2:179969511-179969512(-) m6A 3'UTR       27773535 chr2:179969568-179969569(-) m6A 3'UTR       27773535 chr2:179969577-179969578(-) m6A 3'UTR       27773535 chr2:179969593-179969594(-) m6A 3'UTR       27773535 chr2:179969602-179969603(-) m6A 3'UTR       27773535 chr2:179969614-179969615(-) m6A 3'UTR       27773535 chr2:179969646-179969647(-) m6A 3'UTR       27773535 chr2:179969666-179969667(-) m6A 3'UTR       27773535 chr2:179969731-179969732(-) m6A 3'UTR       27773535 chr2:179969771-179969772(-) m6A 3'UTR       27773535 chr2:179969778-179969779(-) m6A 3'UTR       27773535 chr2:179969817-179969818(-) m6A 3'UTR       24981863//27773535 chr2:179969836-179969837(-) m6A 3'UTR       24981863//27773535 chr2:179969884-179969885(-) m6A 3'UTR       24981863//27773535 chr2:179969899-179969900(-) m6A 3'UTR       24981863//27773535 chr2:179969904-179969905(-) m6A 3'UTR       24981863//27773535 chr2:179969966-179969967(-) m6A 3'UTR       24981863//27773535 chr2:179970028-179970029(-) m6A 3'UTR       27773535 chr2:179970088-179970089(-) m6A 3'UTR       27773535 chr2:179970103-179970104(-) m6A 3'UTR       27773535 chr2:179973139-179973140(-) m6A 3'UTR       27773535 chr2:179973180-179973181(-) m6A 3'UTR       27773535 chr2:179973325-179973326(-) m6A 3'UTR       27773535 chr2:179973358-179973359(-) m6A 3'UTR       27773535 chr2:179974655-179974656(-) m6A 3'UTR//CDS       27371828 chr2:179974685-179974686(-) m6A 3'UTR//CDS       27371828 chr2:179974695-179974696(-) m6A 3'UTR//CDS       27371828 chr2:179974704-179974705(-) m6A 3'UTR//CDS       27371828 chr2:179974748-179974749(-) m6A 3'UTR//CDS       27371828 chr2:179997091-179997092(-) m6A CDS//exon//intron       24981863 chr2:179997120-179997121(-) m6A CDS//exon//intron       24981863 chr2:179997145-179997146(-) m6A CDS//exon//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30a-3p	Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     - Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	SESTD1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30a-3p	Sorafenib 216239 Drug interaction    RC00000903

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30a-3p	Imatinib 5291       25349971

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30a-3p
Interactor2: SESTD1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.