Basic Information:

  VIRBase ID:  

HHID00044897

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:  MIMAT0000088          FAM107B:  NM_001320737     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30a-3p	FAM107B
miRBase Accession/Entrez ID	MIMAT0000088	83641
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C10orf45//HITS

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30a-3p	rs149150037 chr6:71403567    G/A rs149150037 chr6:71403567    G/C rs370184894 chr6:71403566    C/A rs370184894 chr6:71403566    C/T rs552541514 chr6:71403558    C/G rs745605208 chr6:71403563    ATCCG/A rs746505574 chr6:71403557    G/A rs746505574 chr6:71403557    G/T rs746965145 chr6:71403554    GCT/G rs750918072 chr6:71403564    T/C rs765735953 chr6:71403560    A/T rs770865356 chr6:71403559    A/AC rs776574456 chr6:71403560    A/AAGCTGGAGT rs368070339 chr6:71403571    G/A rs769702885 chr6:71403570    TG/T rs775921090 chr6:71403574    AGCC/A rs781617967 chr6:71403573    A/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FAM107B	chr10:14617425(-) A-I      intronic chr10:14624544(-) A-I      intronic chr10:14617384(-) A-I      intronic chr10:14579734(-) A-I      intronic chr10:14642903(-) A-I      intronic chr10:14637604(-) A-I      intronic chr10:14593363(-) A-I      intronic chr10:14604017(-) A-I      intronic chr10:14593394(-) A-I      intronic chr10:14635657(-) A-I      intronic chr10:14603857(-) A-I      intronic chr10:14594606(-) A-I      intronic chr10:14594610(-) A-I      intronic chr10:14593317(-) A-I      intronic chr10:14594667(-) A-I      intronic chr10:14624553(-) A-I      intronic chr10:14594728(-) A-I      intronic chr10:14618302(-) A-I      intronic chr10:14642829(-) A-I      intronic chr10:14618343(-) A-I      intronic chr10:14618346(-) A-I      intronic chr10:14618442(-) A-I      intronic chr10:14624556(-) A-I      intronic chr10:14642823(-) A-I      intronic chr10:14636441(-) A-I      intronic chr10:14624560(-) A-I      intronic chr10:14642777(-) A-I      intronic chr10:14624465(-) A-I      intronic chr10:14642747(-) A-I      intronic chr10:14624468(-) A-I      intronic chr10:14624472(-) A-I      intronic chr10:14624473(-) A-I      intronic chr10:14593228(-) A-I      intronic chr10:14624481(-) A-I      intronic chr10:14624893(-) A-I      intronic chr10:14624504(-) A-I      intronic chr10:14641636(-) A-I      intronic chr10:14624541(-) A-I      intronic chr10:14641634(-) A-I      intronic chr10:14639935(-) A-I      intronic chr10:14639837(-) A-I      intronic chr10:14639825(-) A-I      intronic chr10:14639821(-) A-I      intronic chr10:14639764(-) A-I      intronic chr10:14639703(-) A-I      intronic chr10:14639691(-) A-I      intronic chr10:14624548(-) A-I      intronic chr10:14566124(-) A-I      intronic chr10:14624880(-) A-I      intronic chr10:14579752(-) A-I      intronic chr10:14594746(-) A-I      intronic chr10:14604003(-) A-I      intronic chr10:14593371(-) A-I      intronic chr10:14731876(-) A-I      intronic chr10:14593381(-) A-I      intronic chr10:14668683(-) A-I      intronic chr10:14624571(-) A-I      intronic chr10:14624581(-) A-I      intronic chr10:14636446(-) A-I      intronic chr10:14618522(-) A-I      intronic chr10:14731879(-) A-I      intronic chr10:14637522(-) A-I      intronic chr10:14668641(-) A-I      intronic chr10:14624610(-) A-I      intronic chr10:14593386(-) A-I      intronic chr10:14668686(-) A-I      intronic chr10:14593423(-) A-I      intronic chr10:14636283(-) A-I      intronic chr10:14625039(-) A-I      intronic chr10:14625003(-) A-I      intronic chr10:14624936(-) A-I      intronic chr10:14624928(-) A-I      intronic chr10:14608961(-) A-I      intronic chr10:14617429(-) A-I      intronic chr10:14637521(-) A-I      intronic chr10:14603856(-) A-I      intronic chr10:14643057(-) A-I      intronic chr10:14642753(-) A-I      intronic chr10:14624922(-) A-I      intronic chr10:14636391(-) A-I      intronic chr10:14604057(-) A-I      intronic chr10:14603895(-) A-I      intronic chr10:14624557(-) A-I      intronic chr10:14637603(-) A-I      intronic chr10:14624648(-) A-I      intronic chr10:14618322(-) A-I      intronic chr10:14594745(-) A-I      intronic chr10:14624998(-) A-I      intronic chr10:14594618(-) A-I      intronic chr10:14593245(-) A-I      intronic chr10:14623731(-) A-I      intronic chr10:14617381(-) A-I      intronic chr10:14643038(-) A-I      intronic chr10:14624828(-) A-I      intronic chr10:14624555(-) A-I      intronic chr10:14603922(-) A-I      intronic chr10:14593271(-) A-I      intronic chr10:14612679(-) A-I      intronic chr10:14635617(-) A-I      intronic chr10:14624937(-) A-I      intronic chr10:14624999(-) A-I      intronic chr10:14593285(-) A-I      intronic chr10:14618431(-) A-I      intronic chr10:14623695(-) A-I      intronic chr10:14639783(-) A-I      intronic chr10:14624551(-) A-I      intronic chr10:14625048(-) A-I      intronic chr10:14618321(-) A-I      intronic chr10:14636288(-) A-I      intronic chr10:14624820(-) A-I      intronic chr10:14636408(-) A-I      intronic chr10:14604064(-) A-I      intronic chr10:14624819(-) A-I      intronic chr10:14624445(-) A-I      intronic chr10:14637592(-) A-I      intronic chr10:14692517(-) A-I      intronic chr10:14617308(-) A-I      intronic chr10:14637624(-) A-I      intronic chr10:14642736(-) A-I      intronic chr10:14594773(-) A-I      intronic chr10:14609044(-) A-I      intronic chr10:14637625(-) A-I      intronic chr10:14624487(-) A-I      intronic chr10:14636387(-) A-I      intronic chr10:14623807(-) A-I      intronic chr10:14603846(-) A-I      intronic chr10:14609095(-) A-I      intronic chr10:14643055(-) A-I      intronic chr10:14637517(-) A-I      intronic chr10:14617474(-) A-I      intronic chr10:14639780(-) A-I      intronic chr10:14636421(-) A-I      intronic chr10:14624657(-) A-I      intronic chr10:14642750(-) A-I      intronic chr10:14796043(-) A-I      intronic chr10:14603989(-) A-I      intronic chr10:14612628(-) A-I      intronic chr10:14630223(-) A-I      intronic chr10:14605609(-) A-I      intronic chr10:14625017(-) A-I      intronic chr10:14624840(-) A-I      intronic chr10:14642965(-) A-I      intronic chr10:14625002(-) A-I      intronic chr10:14561836(-) A-I      3'UTR chr10:14574725(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FAM107B	chr10:14603846(-) A-I intron -    15342557 chr10:14603856(-) A-I intron -    15342557 chr10:14603857(-) A-I intron -    15342557 chr10:14603895(-) A-I intron -    15342557 chr10:14603922(-) A-I intron -    15342557 chr10:14603988(-) A-I intron -    15342557 chr10:14603989(-) A-I intron -    15342557 chr10:14604003(-) A-I intron -    15342557 chr10:14604057(-) A-I intron -    15342557 chr10:14604064(-) A-I intron -    15342557 chr10:14605573(-) A-I intron -    15342557 chr10:14605609(-) A-I intron -    15342557 chr10:14608961(-) A-I intron -    15342557 chr10:14609044(-) A-I intron -    15342557 chr10:14609095(-) A-I intron -    15342557 chr10:14609487(-) A-I intron -    15342557 chr10:14574725(-) A-I intron -    21960545 chr10:14641636(-) A-I intron -    21960545 chr10:14624445(-) A-G intron -    22484847 chr10:14624487(-) A-G intron -    22484847 chr10:14624553(-) A-G intron -    22484847 chr10:14624937(-) A-G intron -    22484847 chr10:14636283(-) A-G intron -    22484847 chr10:14636288(-) A-G intron -    22484847 chr10:14643038(-) A-G intron -    22484847 chr10:14643057(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FAM107B	chr10:14561325-14561326(-) m6A 3'UTR       24284625//26404942 chr10:14561359-14561360(-) m6A 3'UTR       24284625//22608085 chr10:14561889-14561890(-) m6A 3'UTR       26404942 chr10:14561924-14561925(-) m6A 3'UTR       26404942 chr10:14562006-14562007(-) m6A 3'UTR       26404942 chr10:14562081-14562082(-) m6A 3'UTR       - chr10:14562222-14562223(-) m6A 3'UTR       26404942 chr10:14562365-14562366(-) m6A 3'UTR       26404942 chr10:14562704-14562705(-) m6A 3'UTR       26404942//27773535 chr10:14562796-14562797(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085 chr10:14562829-14562830(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:14562892-14562893(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:14562906-14562907(-) Gm 3'UTR       - chr10:14562910-14562911(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:14562920-14562921(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:14562933-14562934(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:14562943-14562944(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:14562957-14562958(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:14563170-14563171(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr10:14563223-14563224(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22608085 chr10:14563299-14563300(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//26404942//27773535//22608085 chr10:14563944-14563945(-) Cm 3'UTR//CDS//exon       - chr10:14563958-14563959(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//27773535//22608085 chr10:14564000-14564001(-) m6A 3'UTR//CDS//exon       24981863//28052920//27773535 chr10:14564116-14564117(-) m6A exon//intron       27773535 chr10:14572350-14572351(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535 chr10:14572372-14572373(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535 chr10:14572382-14572383(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535 chr10:14572401-14572402(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535 chr10:14572419-14572420(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535 chr10:14572444-14572445(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535 chr10:14572483-14572484(-) m6A 3'UTR//5'UTR//CDS//exon       26404942//27773535 chr10:14574640-14574641(-) m6A 5'UTR//intron       27773535 chr10:14644551-14644552(-) m6A exon//intron       27773535 chr10:14644601-14644602(-) m6A exon//intron       27773535 chr10:14644744-14644745(-) m6A exon//intron       24981863//26404942 chr10:14644799-14644800(-) m6A exon//intron       24981863//26404942 chr10:14644808-14644809(-) m6A exon//intron       24981863//26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30a-3p	Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     - Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	FAM107B	Cytosol HeLa-S3 cells     - Exosome Blood     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30a-3p	Sorafenib 216239 Drug interaction    RC00000903

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30a-3p	Imatinib 5291       25349971

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30a-3p
Interactor2: FAM107B

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.