Detail Information

Basic Information:


  VIRBase ID:  

HHID00044884

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:           PDLIM1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30a-3p PDLIM1
miRBase
Accession/Entrez ID		 MIMAT0000088 9124
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CLIM1//CLP-36//CLP36//hCLIM1//HEL-S-112

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30a-3p
rs149150037 chr6:71403567    G/A
rs149150037 chr6:71403567    G/C
rs370184894 chr6:71403566    C/A
rs370184894 chr6:71403566    C/T
rs552541514 chr6:71403558    C/G
rs745605208 chr6:71403563    ATCCG/A
rs746505574 chr6:71403557    G/A
rs746505574 chr6:71403557    G/T
rs746965145 chr6:71403554    GCT/G
rs750918072 chr6:71403564    T/C
rs765735953 chr6:71403560    A/T
rs770865356 chr6:71403559    A/AC
rs776574456 chr6:71403560    A/AAGCTGGAGT
rs368070339 chr6:71403571    G/A
rs769702885 chr6:71403570    TG/T
rs775921090 chr6:71403574    AGCC/A
rs781617967 chr6:71403573    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PDLIM1
chr10:97008208(-) A-I      intronic
chr10:97030646(-) A-I      intronic
chr10:97031002(-) A-I      intronic
chr10:97014552(-) A-I      intronic
chr10:97031045(-) A-I      intronic
chr10:97030613(-) A-I      intronic
chr10:97029561(-) A-I      intronic
chr10:97031047(-) A-I      intronic
chr10:97031050(-) A-I      intronic
chr10:97011113(-) A-I      intronic
chr10:97011165(-) A-I      intronic
chr10:97011108(-) A-I      intronic
chr10:97031070(-) A-I      intronic
chr10:97008237(-) A-I      intronic
chr10:97037114(-) A-I      intronic
chr10:97008218(-) A-I      intronic
chr10:97037313(-) A-I      intronic
chr10:97041240(-) A-I      intronic
chr10:97041530(-) A-I      intronic
chr10:97030686(-) A-I      intronic
chr10:97008201(-) A-I      intronic
chr10:97029111(-) A-I      intronic
chr10:97029581(-) A-I      intronic
chr10:97042606(-) A-I      intronic
chr10:97029277(-) A-I      intronic
chr10:97014577(-) A-I      intronic
chr10:97008200(-) A-I      intronic
chr10:97011150(-) A-I      intronic
chr10:97008117(-) A-I      intronic
chr10:97011225(-) A-I      intronic
chr10:97008091(-) A-I      intronic
chr10:97030604(-) A-I      intronic
chr10:97008035(-) A-I      intronic
chr10:97011221(-) A-I      intronic
chr10:97029555(-) A-I      intronic
chr10:97029766(-) A-I      intronic
chr10:97029692(-) A-I      intronic
chr10:97029630(-) A-I      intronic
chr10:97031180(-) A-I      intronic
chr10:97008130(-) A-I      intronic
chr10:97029282(-) A-I      intronic
chr10:97029243(-) A-I      intronic
chr10:97029099(-) A-I      intronic
chr10:97029767(-) A-I      intronic
chr10:97030636(-) A-I      intronic
chr10:97030659(-) A-I      intronic
chr10:97008242(-) A-I      intronic
chr10:97030600(-) A-I      intronic
chr10:97046070(-) A-I      intronic
chr10:97031082(-) A-I      intronic
chr10:97031028(-) A-I      intronic
chr10:97008280(-) A-I      intronic
chr10:97041506(-) A-I      intronic
chr10:97031112(-) A-I      intronic
chr10:97011161(-) A-I      intronic
chr10:97029789(-) A-I      intronic
chr10:97044275(-) A-I      intronic
chr10:97030687(-) A-I      intronic
chr10:97008094(-) A-I      intronic
chr10:97008144(-) A-I      intronic
chr10:97030943(-) A-I      intronic
chr10:97011257(-) A-I      intronic
chr10:97008080(-) A-I      intronic
chr10:97014565(-) A-I      intronic
chr10:97029094(-) A-I      intronic
chr10:97031147(-) A-I      intronic
chr10:97031111(-) A-I      intronic
chr10:97030536(-) A-I      intronic
chr10:97004594(-) A-I      intronic
chr10:97029660(-) A-I      intronic
chr10:97029172(-) A-I      intronic
chr10:97037317(-) A-I      intronic
chr10:97037314(-) A-I      intronic
chr10:97041093(-) A-I      intronic
chr10:97030781(-) A-I      intronic
chr10:97014429(-) A-I      intronic
chr10:97029315(-) A-I      intronic
chr10:97030619(-) A-I      intronic
chr10:97029582(-) A-I      intronic
chr10:97030605(-) A-I      intronic
chr10:97008152(-) A-I      intronic
chr10:97042479(-) A-I      intronic
chr10:97029590(-) A-I      intronic
chr10:97011185(-) A-I      intronic
chr10:97011233(-) A-I      intronic
chr10:97011109(-) A-I      intronic
chr10:97008204(-) A-I      intronic
chr10:97008168(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PDLIM1
chr10:97023622-97023623(-) m6A CDS//exon       27773535
chr10:97023629-97023630(-) m6A CDS//exon       27773535
chr10:97023654-97023655(-) m6A CDS//exon       24981863//27773535
chr10:97023728-97023729(-) m6A CDS//exon       24981863//27773535
chr10:97028540-97028541(-) m6A CDS//exon       27773535
chr10:97028612-97028613(-) m6A CDS//exon       27773535
chr10:97033151-97033152(-) m6A exon//intron       27773536
chr10:97050604-97050605(-) m6A CDS//exon       27773536
chr10:97050652-97050653(-) m6A CDS//exon       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30a-3p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
PDLIM1
Chromatin K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30a-3p
Sorafenib 216239 Drug interaction    RC00000903
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30a-3p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30a-3p
Interactor2: PDLIM1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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