Detail Information

Basic Information:


  VIRBase ID:  

HHID00044879

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:           PPP3R1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30a-3p PPP3R1
miRBase
Accession/Entrez ID		 MIMAT0000088 5534
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CALNB1//CNB//CNB1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30a-3p
rs149150037 chr6:71403567    G/A
rs149150037 chr6:71403567    G/C
rs370184894 chr6:71403566    C/A
rs370184894 chr6:71403566    C/T
rs552541514 chr6:71403558    C/G
rs745605208 chr6:71403563    ATCCG/A
rs746505574 chr6:71403557    G/A
rs746505574 chr6:71403557    G/T
rs746965145 chr6:71403554    GCT/G
rs750918072 chr6:71403564    T/C
rs765735953 chr6:71403560    A/T
rs770865356 chr6:71403559    A/AC
rs776574456 chr6:71403560    A/AAGCTGGAGT
rs368070339 chr6:71403571    G/A
rs769702885 chr6:71403570    TG/T
rs775921090 chr6:71403574    AGCC/A
rs781617967 chr6:71403573    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PPP3R1
chr2:68407454(-) A-I      3'UTR
chr2:68407450(-) A-I      3'UTR
chr2:68407373(-) A-I      3'UTR
chr2:68407350(-) A-I      3'UTR
chr2:68407346(-) A-I      3'UTR
chr2:68407332(-) A-I      3'UTR
chr2:68407321(-) A-I      3'UTR
chr2:68472412(-) A-I      intronic
chr2:68472437(-) A-I      intronic
chr2:68407249(-) A-I      3'UTR
chr2:68425422(-) A-I      intronic
chr2:68425446(-) A-I      intronic
chr2:68425450(-) A-I      intronic
chr2:68407489(-) A-I      3'UTR
chr2:68407490(-) A-I      3'UTR
chr2:68407503(-) A-I      3'UTR
chr2:68407506(-) A-I      3'UTR
chr2:68407456(-) A-I      3'UTR
chr2:68473376(-) A-I      intronic
chr2:68425416(-) A-I      intronic
chr2:68472377(-) A-I      intronic
chr2:68407516(-) A-I      3'UTR
chr2:68407526(-) A-I      3'UTR
chr2:68407507(-) A-I      3'UTR
chr2:68473384(-) A-I      intronic
chr2:68473400(-) A-I      intronic
chr2:68436882(-) A-I      intronic
chr2:68407527(-) A-I      3'UTR
chr2:68474357(-) A-I      intronic
chr2:68474156(-) A-I      intronic
chr2:68473486(-) A-I      intronic
chr2:68473472(-) A-I      intronic
chr2:68473410(-) A-I      intronic
chr2:68473408(-) A-I      intronic
chr2:68432460(-) A-I      intronic
chr2:68432511(-) A-I      intronic
chr2:68432635(-) A-I      intronic
chr2:68439285(-) A-I      intronic
chr2:68439321(-) A-I      intronic
chr2:68435199(-) A-I      intronic
chr2:68439341(-) A-I      intronic
chr2:68435915(-) A-I      intronic
chr2:68435947(-) A-I      intronic
chr2:68436632(-) A-I      intronic
chr2:68439351(-) A-I      intronic
chr2:68439407(-) A-I      intronic
chr2:68459473(-) A-I      intronic
chr2:68459559(-) A-I      intronic
chr2:68459811(-) A-I      intronic
chr2:68459871(-) A-I      intronic
chr2:68459893(-) A-I      intronic
chr2:68472236(-) A-I      intronic
chr2:68436656(-) A-I      intronic
chr2:68472260(-) A-I      intronic
chr2:68459921(-) A-I      intronic
chr2:68472300(-) A-I      intronic
chr2:68472364(-) A-I      intronic
chr2:68472382(-) A-I      intronic
chr2:68472394(-) A-I      intronic
chr2:68436778(-) A-I      intronic
chr2:68473254(-) A-I      intronic
chr2:68473279(-) A-I      intronic
chr2:68436667(-) A-I      intronic
chr2:68436849(-) A-I      intronic
chr2:68439282(-) A-I      intronic
chr2:68416743(-) A-I      intronic
chr2:68429629(-) A-I      intronic
chr2:68429713(-) A-I      intronic
chr2:68429848(-) A-I      intronic
chr2:68473331(-) A-I      intronic
chr2:68429642(-) A-I      intronic
chr2:68429802(-) A-I      intronic
chr2:68435933(-) A-I      intronic
chr2:68429761(-) A-I      intronic
chr2:68429750(-) A-I      intronic
chr2:68473371(-) A-I      intronic
chr2:68429760(-) A-I      intronic
chr2:68472411(-) A-I      intronic
chr2:68472246(-) A-I      intronic
chr2:68459451(-) A-I      intronic
chr2:68472418(-) A-I      intronic
chr2:68473344(-) A-I      intronic
chr2:68474257(-) A-I      intronic
chr2:68432553(-) A-I      intronic
chr2:68459876(-) A-I      intronic
chr2:68473377(-) A-I      intronic
chr2:68429685(-) A-I      intronic
chr2:68432583(-) A-I      intronic
chr2:68429836(-) A-I      intronic
chr2:68435222(-) A-I      intronic
chr2:68459567(-) A-I      intronic
chr2:68473315(-) A-I      intronic
chr2:68435986(-) A-I      intronic
chr2:68461461(-) A-I      intronic
chr2:68459894(-) A-I      intronic
chr2:68439477(-) A-I      intronic
chr2:68469396(-) A-I      intronic
chr2:68474314(-) A-I      intronic
chr2:68472350(-) A-I      intronic
chr2:68439412(-) A-I      intronic
chr2:68429694(-) A-I      intronic
chr2:68429649(-) A-I      intronic
chr2:68474291(-) A-I      intronic
chr2:68435810(-) A-I      intronic
chr2:68429659(-) A-I      intronic
chr2:68473313(-) A-I      intronic
chr2:68432663(-) A-I      intronic
chr2:68473335(-) A-I      intronic
chr2:68472320(-) A-I      intronic
chr2:68432503(-) A-I      intronic
chr2:68472385(-) A-I      intronic
chr2:68430073(-) A-I      intronic
chr2:68473427(-) A-I      intronic
chr2:68439350(-) A-I      intronic
chr2:68439275(-) A-I      intronic
chr2:68468783(-) A-I      intronic
chr2:68430007(-) A-I      intronic
chr2:68435066(-) A-I      intronic
chr2:68472477(-) A-I      intronic
chr2:68430694(-) A-I      intronic
chr2:68451523(-) A-I      intronic
chr2:68472372(-) A-I      intronic
chr2:68460014(-) A-I      intronic
chr2:68435125(-) A-I      intronic
chr2:68430490(-) A-I      intronic
chr2:68439392(-) A-I      intronic
chr2:68473303(-) A-I      intronic
chr2:68435115(-) A-I      intronic
chr2:68474360(-) A-I      intronic
chr2:68457179(-) A-I      intronic
chr2:68473478(-) A-I      intronic
chr2:68439492(-) A-I      intronic
chr2:68474358(-) A-I      intronic
chr2:68438349(-) A-I      intronic
chr2:68430477(-) A-I      intronic
chr2:68474256(-) A-I      intronic
chr2:68430031(-) A-I      intronic
chr2:68435998(-) A-I      intronic
chr2:68432512(-) A-I      intronic
chr2:68436011(-) A-I      intronic
chr2:68435166(-) A-I      intronic
chr2:68432632(-) A-I      intronic
chr2:68459903(-) A-I      intronic
chr2:68435216(-) A-I      intronic
chr2:68412264(-) A-I      intronic
chr2:68436623(-) A-I      intronic
chr2:68461353(-) A-I      intronic
chr2:68430091(-) A-I      intronic
chr2:68474252(-) A-I      intronic
chr2:68468736(-) A-I      intronic
chr2:68473274(-) A-I      intronic
chr2:68472442(-) A-I      intronic
chr2:68473318(-) A-I      intronic
chr2:68432539(-) A-I      intronic
chr2:68473283(-) A-I      intronic
chr2:68472425(-) A-I      intronic
chr2:68435862(-) A-I      intronic
chr2:68460019(-) A-I      intronic
chr2:68473345(-) A-I      intronic
chr2:68430032(-) A-I      intronic
chr2:68436008(-) A-I      intronic
chr2:68435890(-) A-I      intronic
chr2:68472468(-) A-I      intronic
chr2:68461286(-) A-I      intronic
chr2:68432513(-) A-I      intronic
chr2:68432640(-) A-I      intronic
chr2:68430646(-) A-I      intronic
chr2:68430568(-) A-I      intronic
chr2:68474226(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PPP3R1
chr2:68429642(-) A-I intron -    22028664
chr2:68429649(-) A-I intron -    22028664
chr2:68429659(-) A-I intron -    22028664
chr2:68429685(-) A-I intron -    22028664
chr2:68429694(-) A-I intron -    22028664
chr2:68429695(-) A-I intron -    22028664
chr2:68429750(-) A-I intron -    22028664
chr2:68429760(-) A-I intron -    22028664
chr2:68429761(-) A-I intron -    22028664
chr2:68429802(-) A-I intron -    22028664
chr2:68429803(-) A-I intron -    22028664
chr2:68429836(-) A-I intron -    22028664
chr2:68406155(-) C-T exon 3'UTR    21725310
chr2:68438027(-) A-G intron -    22484847
chr2:68429695(-) A-G intron -    22484847
chr2:68430733(-) G-T intron -    22484847
chr2:68432485(-) G-C intron -    22484847
chr2:68432632(-) A-G intron -    22484847
chr2:68432640(-) A-G intron -    22484847
chr2:68432663(-) A-G intron -    22484847
chr2:68435046(-) T-C intron -    22484847
chr2:68435096(-) A-G intron -    22484847
chr2:68435115(-) A-G intron -    22484847
chr2:68435125(-) A-G intron -    22484847
chr2:68435166(-) A-G intron -    22484847
chr2:68435222(-) A-G intron -    22484847
chr2:68435890(-) A-G intron -    22484847
chr2:68435979(-) A-G intron -    22484847
chr2:68435986(-) A-G intron -    22484847
chr2:68435998(-) A-G intron -    22484847
chr2:68436008(-) A-G intron -    22484847
chr2:68436011(-) A-G intron -    22484847
chr2:68436697(-) A-G intron -    22484847
chr2:68439273(-) A-G intron -    22484847
chr2:68439275(-) A-G intron -    22484847
chr2:68439350(-) A-G intron -    22484847
chr2:68439392(-) A-G intron -    22484847
chr2:68439395(-) A-G intron -    22484847
chr2:68439406(-) A-G intron -    22484847
chr2:68439412(-) A-G intron -    22484847
chr2:68439492(-) A-G intron -    22484847
chr2:68459451(-) A-G intron -    22484847
chr2:68459567(-) A-G intron -    22484847
chr2:68459876(-) A-G intron -    22484847
chr2:68459903(-) A-G intron -    22484847
chr2:68460014(-) A-G intron -    22484847
chr2:68460019(-) A-G intron -    22484847
chr2:68461353(-) A-G intron -    22484847
chr2:68473313(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PPP3R1
chr2:68407680-68407681(-) Y 3'UTR       25219674
chr2:68407882-68407883(-) m6A 3'UTR       24284625//24981863//28052920//26404942//27371828//22608085
chr2:68407929-68407930(-) m6A 3'UTR       24284625//24981863//28052920//26404942//27371828//22608085
chr2:68413658-68413659(-) m6A CDS       26404942
chr2:68413663-68413664(-) m6A CDS       26404942
chr2:68413699-68413700(-) m6A CDS       26404942
chr2:68413731-68413732(-) m6A CDS       26404942
chr2:68415653-68415654(-) m6A CDS       26404942
chr2:68415751-68415752(-) Gm CDS       -
chr2:68415767-68415768(-) m6A CDS       22575960
chr2:68483202-68483203(-) m6A CDS       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30a-3p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
PPP3R1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30a-3p
Sorafenib 216239 Drug interaction    RC00000903
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30a-3p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30a-3p
Interactor2: PPP3R1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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