Basic Information:

  VIRBase ID:  

HHID00044878

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:  MIMAT0000088          PPARD:  NM_001171818     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30a-3p	PPARD
miRBase Accession/Entrez ID	MIMAT0000088	5467
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	FAAR//NR1C2//NUC1//NUCI//NUCII//PPARB

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30a-3p	rs149150037 chr6:71403567    G/A rs149150037 chr6:71403567    G/C rs370184894 chr6:71403566    C/A rs370184894 chr6:71403566    C/T rs552541514 chr6:71403558    C/G rs745605208 chr6:71403563    ATCCG/A rs746505574 chr6:71403557    G/A rs746505574 chr6:71403557    G/T rs746965145 chr6:71403554    GCT/G rs750918072 chr6:71403564    T/C rs765735953 chr6:71403560    A/T rs770865356 chr6:71403559    A/AC rs776574456 chr6:71403560    A/AAGCTGGAGT rs368070339 chr6:71403571    G/A rs769702885 chr6:71403570    TG/T rs775921090 chr6:71403574    AGCC/A rs781617967 chr6:71403573    A/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PPARD	chr6:35359965(+) A-I      intronic chr6:35360000(+) A-I      intronic chr6:35360007(+) A-I      intronic chr6:35360012(+) A-I      intronic chr6:35323579(+) A-I      intronic chr6:35323482(+) A-I      intronic chr6:35323469(+) A-I      intronic chr6:35321859(+) A-I      intronic chr6:35323335(+) A-I      intronic chr6:35358645(+) A-I      intronic chr6:35323317(+) A-I      intronic chr6:35323176(+) A-I      intronic chr6:35323088(+) A-I      intronic chr6:35323077(+) A-I      intronic chr6:35323068(+) A-I      intronic chr6:35322346(+) A-I      intronic chr6:35322338(+) A-I      intronic chr6:35322263(+) A-I      intronic chr6:35322121(+) A-I      intronic chr6:35321894(+) A-I      intronic chr6:35321888(+) A-I      intronic chr6:35321862(+) A-I      intronic chr6:35385001(+) A-I      intronic chr6:35385192(+) A-I      intronic chr6:35321857(+) A-I      intronic chr6:35385290(+) A-I      intronic chr6:35385257(+) A-I      intronic chr6:35372964(+) A-I      intronic chr6:35364075(+) A-I      intronic chr6:35372960(+) A-I      intronic chr6:35372952(+) A-I      intronic chr6:35323178(+) A-I      intronic chr6:35323173(+) A-I      intronic chr6:35323170(+) A-I      intronic chr6:35321793(+) A-I      intronic chr6:35321826(+) A-I      intronic chr6:35321855(+) A-I      intronic chr6:35384136(+) A-I      intronic chr6:35384135(+) A-I      intronic chr6:35323167(+) A-I      intronic chr6:35323153(+) A-I      intronic chr6:35384096(+) A-I      intronic chr6:35384092(+) A-I      intronic chr6:35384083(+) A-I      intronic chr6:35384072(+) A-I      intronic chr6:35384071(+) A-I      intronic chr6:35384057(+) A-I      intronic chr6:35383968(+) A-I      intronic chr6:35383925(+) A-I      intronic chr6:35383903(+) A-I      intronic chr6:35383895(+) A-I      intronic chr6:35383885(+) A-I      intronic chr6:35379960(+) A-I      intronic chr6:35379872(+) A-I      intronic chr6:35321830(+) A-I      intronic chr6:35379842(+) A-I      intronic chr6:35379823(+) A-I      intronic chr6:35373691(+) A-I      intronic chr6:35368480(+) A-I      intronic chr6:35367456(+) A-I      intronic chr6:35367001(+) A-I      intronic chr6:35366960(+) A-I      intronic chr6:35347061(+) A-I      intronic chr6:35366825(+) A-I      intronic chr6:35366815(+) A-I      intronic chr6:35364627(+) A-I      intronic chr6:35364564(+) A-I      intronic chr6:35364532(+) A-I      intronic chr6:35364500(+) A-I      intronic chr6:35364496(+) A-I      intronic chr6:35364134(+) A-I      intronic chr6:35364111(+) A-I      intronic chr6:35340048(+) A-I      intronic chr6:35341508(+) A-I      intronic chr6:35341521(+) A-I      intronic chr6:35341539(+) A-I      intronic chr6:35341590(+) A-I      intronic chr6:35342179(+) A-I      intronic chr6:35318942(+) A-I      intronic chr6:35319004(+) A-I      intronic chr6:35319009(+) A-I      intronic chr6:35364068(+) A-I      intronic chr6:35342180(+) A-I      intronic chr6:35342249(+) A-I      intronic chr6:35342276(+) A-I      intronic chr6:35343064(+) A-I      intronic chr6:35343088(+) A-I      intronic chr6:35343193(+) A-I      intronic chr6:35344682(+) A-I      intronic chr6:35347055(+) A-I      intronic chr6:35358571(+) A-I      intronic chr6:35347078(+) A-I      intronic chr6:35347081(+) A-I      intronic chr6:35347090(+) A-I      intronic chr6:35356282(+) A-I      intronic chr6:35356310(+) A-I      intronic chr6:35364043(+) A-I      intronic chr6:35362437(+) A-I      intronic chr6:35356324(+) A-I      intronic chr6:35362377(+) A-I      intronic chr6:35362341(+) A-I      intronic chr6:35358657(+) A-I      intronic chr6:35384147(+) A-I      intronic chr6:35384819(+) A-I      intronic chr6:35384970(+) A-I      intronic chr6:35384978(+) A-I      intronic chr6:35385033(+) A-I      intronic chr6:35385506(+) A-I      intronic chr6:35385529(+) A-I      intronic chr6:35389189(+) A-I      intronic chr6:35389195(+) A-I      intronic chr6:35356818(+) A-I      intronic chr6:35356835(+) A-I      intronic chr6:35357147(+) A-I      intronic chr6:35357192(+) A-I      intronic chr6:35357218(+) A-I      intronic chr6:35357254(+) A-I      intronic chr6:35357287(+) A-I      intronic chr6:35358528(+) A-I      intronic chr6:35358538(+) A-I      intronic chr6:35358550(+) A-I      intronic chr6:35385357(+) A-I      intronic chr6:35346980(+) A-I      intronic chr6:35356362(+) A-I      intronic chr6:35322275(+) A-I      intronic chr6:35384101(+) A-I      intronic chr6:35343577(+) A-I      intronic chr6:35383983(+) A-I      intronic chr6:35342385(+) A-I      intronic chr6:35342255(+) A-I      intronic chr6:35323056(+) A-I      intronic chr6:35356330(+) A-I      intronic chr6:35342320(+) A-I      intronic chr6:35344524(+) A-I      intronic chr6:35384030(+) A-I      intronic chr6:35323051(+) A-I      intronic chr6:35384031(+) A-I      intronic chr6:35358617(+) A-I      intronic chr6:35344591(+) A-I      intronic chr6:35381530(+) A-I      intronic chr6:35377148(+) A-I      intronic chr6:35323587(+) A-I      intronic chr6:35358653(+) A-I      intronic chr6:35385492(+) A-I      intronic chr6:35358620(+) A-I      intronic chr6:35332311(+) A-I      intronic chr6:35377083(+) A-I      intronic chr6:35348398(+) A-I      intronic chr6:35342272(+) A-I      intronic chr6:35322258(+) A-I      intronic chr6:35385163(+) A-I      intronic chr6:35366657(+) A-I      intronic chr6:35344542(+) A-I      intronic chr6:35342324(+) A-I      intronic chr6:35323036(+) A-I      intronic chr6:35358585(+) A-I      intronic chr6:35354223(+) A-I      intronic chr6:35385413(+) A-I      intronic chr6:35341484(+) A-I      intronic chr6:35344536(+) A-I      intronic chr6:35343592(+) A-I      intronic chr6:35313087(+) A-I      intronic chr6:35322142(+) A-I      intronic chr6:35347020(+) A-I      intronic chr6:35358649(+) A-I      intronic chr6:35392962(+) A-I      3'UTR chr6:35323311(+) A-I      intronic chr6:35322356(+) A-I      intronic chr6:35321997(+) A-I      intronic chr6:35317619(+) A-I      intronic chr6:35366745(+) A-I      intronic chr6:35322207(+) A-I      intronic chr6:35344650(+) A-I      intronic chr6:35358641(+) A-I      intronic chr6:35379943(+) A-I      intronic chr6:35344620(+) A-I      intronic chr6:35347140(+) A-I      intronic chr6:35385325(+) A-I      intronic chr6:35383909(+) A-I      intronic chr6:35366897(+) A-I      intronic chr6:35322336(+) A-I      intronic chr6:35385371(+) A-I      intronic chr6:35385094(+) A-I      intronic chr6:35344659(+) A-I      intronic chr6:35385313(+) A-I      intronic chr6:35322277(+) A-I      intronic chr6:35344693(+) A-I      intronic chr6:35323564(+) A-I      intronic chr6:35384886(+) A-I      intronic chr6:35356950(+) A-I      intronic chr6:35366951(+) A-I      intronic chr6:35384808(+) A-I      intronic chr6:35323595(+) A-I      intronic chr6:35367461(+) A-I      intronic chr6:35383981(+) A-I      intronic chr6:35355547(+) A-I      intronic chr6:35357228(+) A-I      intronic chr6:35341469(+) A-I      intronic chr6:35340016(+) A-I      intronic chr6:35384818(+) A-I      intronic chr6:35379982(+) A-I      intronic chr6:35342356(+) A-I      intronic chr6:35344534(+) A-I      intronic chr6:35384829(+) A-I      intronic chr6:35322244(+) A-I      intronic chr6:35344610(+) A-I      intronic chr6:35323248(+) A-I      intronic chr6:35355555(+) A-I      intronic chr6:35385408(+) A-I      intronic chr6:35385518(+) A-I      intronic chr6:35385438(+) A-I      intronic chr6:35323075(+) A-I      intronic chr6:35356409(+) A-I      intronic chr6:35323254(+) A-I      intronic chr6:35333542(+) A-I      intronic chr6:35341557(+) A-I      intronic chr6:35355518(+) A-I      intronic chr6:35356368(+) A-I      intronic chr6:35347159(+) A-I      intronic chr6:35344600(+) A-I      intronic chr6:35385409(+) A-I      intronic chr6:35373762(+) A-I      intronic chr6:35356382(+) A-I      intronic chr6:35319064(+) A-I      intronic chr6:35366733(+) A-I      intronic chr6:35347141(+) A-I      intronic chr6:35344676(+) A-I      intronic chr6:35372974(+) A-I      intronic chr6:35364691(+) A-I      intronic chr6:35356329(+) A-I      intronic chr6:35356410(+) A-I      intronic chr6:35373500(+) A-I      intronic chr6:35388703(+) A-I      intronic chr6:35323208(+) A-I      intronic chr6:35348506(+) A-I      intronic chr6:35356404(+) A-I      intronic chr6:35321763(+) A-I      intronic chr6:35323127(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PPARD	chr6:35379725(+) A-I intron -    21960545 chr6:35353374(+) C-A intron -    21725310 chr6:35321898(+) A-G intron -    22484847 chr6:35322207(+) A-G intron -    22484847 chr6:35322243(+) A-G intron -    22484847 chr6:35322244(+) A-G intron -    22484847 chr6:35322258(+) A-G intron -    22484847 chr6:35322275(+) A-G intron -    22484847 chr6:35322277(+) A-G intron -    22484847 chr6:35322278(+) A-G intron -    22484847 chr6:35323036(+) A-G intron -    22484847 chr6:35323051(+) A-G intron -    22484847 chr6:35323056(+) A-G intron -    22484847 chr6:35323075(+) A-G intron -    22484847 chr6:35323208(+) A-G intron -    22484847 chr6:35323564(+) A-G intron -    22484847 chr6:35323587(+) A-G intron -    22484847 chr6:35323595(+) A-G intron -    22484847 chr6:35325566(+) G-A intron -    22484847 chr6:35333536(+) A-G intron -    22484847 chr6:35340016(+) A-G intron -    22484847 chr6:35340055(+) A-G intron -    22484847 chr6:35341450(+) C-T intron -    22484847 chr6:35341469(+) A-G intron -    22484847 chr6:35341545(+) A-G intron -    22484847 chr6:35341648(+) A-G intron -    22484847 chr6:35341691(+) A-G intron -    22484847 chr6:35341700(+) A-G intron -    22484847 chr6:35341713(+) A-G intron -    22484847 chr6:35342272(+) A-G intron -    22484847 chr6:35342288(+) A-G intron -    22484847 chr6:35342320(+) A-G intron -    22484847 chr6:35344591(+) A-G intron -    22484847 chr6:35344620(+) A-G intron -    22484847 chr6:35346873(+) C-T intron -    22484847 chr6:35346980(+) A-G intron -    22484847 chr6:35346981(+) A-G intron -    22484847 chr6:35347095(+) A-G intron -    22484847 chr6:35357358(+) A-G intron -    22484847 chr6:35379892(+) A-G intron -    22484847 chr6:35381586(+) A-G intron -    22484847 chr6:35384808(+) A-G intron -    22484847 chr6:35385569(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PPARD	chr6:35310364-35310365(+) m6A 5'UTR       24981863 chr6:35310454-35310455(+) m6A 5'UTR       24284625//24209618 chr6:35314910-35314911(+) m6A 5'UTR       24284625//24209618 chr6:35378773-35378774(+) m6A 5'UTR//intron       24209618 chr6:35378803-35378804(+) m6A 5'UTR//intron       24209618//25456834 chr6:35378959-35378960(+) m6A CDS//intron       24209618//25456834 chr6:35387939-35387940(+) m6A CDS//intron       - chr6:35388008-35388009(+) m6A CDS//intron       24284625 chr6:35389672-35389673(+) m6A CDS//intron       24284625 chr6:35392684-35392685(+) m6A 3'UTR//intron       24981863 chr6:35393653-35393654(+) m6A CDS       24284625 chr6:35393796-35393797(+) m6A CDS       24284625//24209618//25456834//24981863//22575960 chr6:35393802-35393803(+) m6A CDS       24284625//24209618//25456834//24981863//22575960 chr6:35393808-35393809(+) m6A CDS       24284625//24209618//25456834//24981863//22575960 chr6:35393845-35393846(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:35393881-35393882(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:35393985-35393986(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr6:35394238-35394239(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr6:35394243-35394244(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr6:35394362-35394363(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:35394381-35394382(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:35394431-35394432(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:35394475-35394476(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:35394521-35394522(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:35394811-35394812(+) m6A 3'UTR       - chr6:35395515-35395516(+) m6A 3'UTR       24284625 chr6:35395740-35395741(+) m6A 3'UTR       - chr6:35395752-35395753(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30a-3p	Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     - Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	PPARD	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30a-3p	Sorafenib 216239 Drug interaction    RC00000903

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30a-3p	Imatinib 5291       25349971

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30a-3p
Interactor2: PPARD

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.