Detail Information

Basic Information:


  VIRBase ID:  

HHID00044872

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:           TSC22D3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30a-3p TSC22D3
miRBase
Accession/Entrez ID		 MIMAT0000088 1831
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DIP//DSIPI//GILZ//TSC-22R

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30a-3p
rs149150037 chr6:71403567    G/A
rs149150037 chr6:71403567    G/C
rs370184894 chr6:71403566    C/A
rs370184894 chr6:71403566    C/T
rs552541514 chr6:71403558    C/G
rs745605208 chr6:71403563    ATCCG/A
rs746505574 chr6:71403557    G/A
rs746505574 chr6:71403557    G/T
rs746965145 chr6:71403554    GCT/G
rs750918072 chr6:71403564    T/C
rs765735953 chr6:71403560    A/T
rs770865356 chr6:71403559    A/AC
rs776574456 chr6:71403560    A/AAGCTGGAGT
rs368070339 chr6:71403571    G/A
rs769702885 chr6:71403570    TG/T
rs775921090 chr6:71403574    AGCC/A
rs781617967 chr6:71403573    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TSC22D3
chrX:107006255(-) A-I      intronic
chrX:107006251(-) A-I      intronic
chrX:107001136(-) A-I      intronic
chrX:107006195(-) A-I      intronic
chrX:107001209(-) A-I      intronic
chrX:107002207(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TSC22D3
chrX:106957269-106957270(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chrX:106957375-106957376(-) m6A 3'UTR       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chrX:106957577-106957578(-) m6A 3'UTR       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chrX:106957608-106957609(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chrX:106957650-106957651(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chrX:106957713-106957714(-) m6A 3'UTR       24284625//24981863//28052920//27773535//22575960//22608085
chrX:106957858-106957859(-) m6A CDS       24284625//24981863//27773535//27371828//27773536
chrX:106957872-106957873(-) m6A CDS       24284625//24981863//27773535//27371828//27773536
chrX:106957893-106957894(-) m6A CDS       24284625//24981863//28052920//27773535//27371828//27773536
chrX:106957918-106957919(-) Cm CDS       -
chrX:106959027-106959028(-) m6A CDS//intron       24981863//28052920//27773535//27371828//27773536
chrX:106959137-106959138(-) m6A 5'UTR//CDS       24981863
chrX:106959150-106959151(-) m6A 5'UTR//CDS       24981863
chrX:106959220-106959221(-) m6A 5'UTR//intron       24981863
chrX:106959255-106959256(-) m6A 5'UTR//intron       25456834//24981863//27773536
chrX:106959312-106959313(-) m6A 5'UTR//intron       25456834//24981863//27371828//27773536//22608085
chrX:106959326-106959327(-) m6A 5'UTR//intron       25456834//24981863//27371828//27773536//22608085
chrX:106959407-106959408(-) m6A 5'UTR//intron       27773536//22608085
chrX:106959434-106959435(-) m6A 5'UTR//intron       27773536
chrX:106959505-106959506(-) m6A 5'UTR//intron       27773536
chrX:106959528-106959529(-) m6A 5'UTR//intron       27773536
chrX:106959643-106959644(-) m6A 5'UTR//intron       25456834//27773536
chrX:106959648-106959649(-) m6A 5'UTR//intron       25456834//27773536
chrX:106959700-106959701(-) m6A 5'UTR//intron       27773536
chrX:106960019-106960020(-) m6A CDS//intron       24981863//28052920//27371828//27773536
chrX:106960036-106960037(-) m6A CDS//intron       24981863//28052920//27371828//27773536
chrX:106960071-106960072(-) m6A 5'UTR//intron       24981863//27371828//27773536
chrX:106960146-106960147(-) m6A 5'UTR//intron       24981863//27371828//27773536
chrX:106960278-106960279(-) m6A 5'UTR//intron       27371828//27773536
chrX:107018473-107018474(-) m6A 5'UTR//CDS       27773536//22608085
chrX:107018539-107018540(-) m6A CDS//intron       27371828//27773536//22608085
chrX:107018584-107018585(-) m6A CDS//intron       27371828//27773536//22608085
chrX:107018970-107018971(-) m6A 5'UTR//intron       24284625//27773536
chrX:107018977-107018978(-) m6A 5'UTR//intron       27773536
chrX:107019098-107019099(-) m6A 5'UTR//intron       27773536
chrX:107019184-107019185(-) m6A 5'UTR//intron       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30a-3p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
TSC22D3
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30a-3p
Sorafenib 216239 Drug interaction    RC00000903
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30a-3p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30a-3p
Interactor2: TSC22D3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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