Detail Information

Basic Information:


  VIRBase ID:  

HHID00044869

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:           CHUK:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30a-3p CHUK
miRBase
Accession/Entrez ID		 MIMAT0000088 1147
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IKBKA//IKK-alpha//IKK1//IKKA//NFKBIKA//TCF16

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30a-3p
rs149150037 chr6:71403567    G/A
rs149150037 chr6:71403567    G/C
rs370184894 chr6:71403566    C/A
rs370184894 chr6:71403566    C/T
rs552541514 chr6:71403558    C/G
rs745605208 chr6:71403563    ATCCG/A
rs746505574 chr6:71403557    G/A
rs746505574 chr6:71403557    G/T
rs746965145 chr6:71403554    GCT/G
rs750918072 chr6:71403564    T/C
rs765735953 chr6:71403560    A/T
rs770865356 chr6:71403559    A/AC
rs776574456 chr6:71403560    A/AAGCTGGAGT
rs368070339 chr6:71403571    G/A
rs769702885 chr6:71403570    TG/T
rs775921090 chr6:71403574    AGCC/A
rs781617967 chr6:71403573    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CHUK
chr10:101971736(-) A-I      intronic
chr10:101983246(-) A-I      intronic
chr10:101981559(-) A-I      intronic
chr10:101968034(-) A-I      intronic
chr10:101973070(-) A-I      intronic
chr10:101983283(-) A-I      intronic
chr10:101983208(-) A-I      intronic
chr10:101971816(-) A-I      intronic
chr10:101981583(-) A-I      intronic
chr10:101981688(-) A-I      intronic
chr10:101984771(-) A-I      intronic
chr10:101981594(-) A-I      intronic
chr10:101983247(-) A-I      intronic
chr10:101957550(-) A-I      intronic
chr10:101981588(-) A-I      intronic
chr10:101968043(-) A-I      intronic
chr10:101968481(-) A-I      intronic
chr10:101972994(-) A-I      intronic
chr10:101977510(-) A-I      intronic
chr10:101971807(-) A-I      intronic
chr10:101968041(-) A-I      intronic
chr10:101967925(-) A-I      intronic
chr10:101971732(-) A-I      intronic
chr10:101968535(-) A-I      intronic
chr10:101968010(-) A-I      intronic
chr10:101962678(-) A-I      intronic
chr10:101973093(-) A-I      intronic
chr10:101968302(-) A-I      intronic
chr10:101967961(-) A-I      intronic
chr10:101968410(-) A-I      intronic
chr10:101968394(-) A-I      intronic
chr10:101973072(-) A-I      intronic
chr10:101988351(-) A-I      intronic
chr10:101973521(-) A-I      intronic
chr10:101949650(-) A-I      intronic
chr10:101973035(-) A-I      intronic
chr10:101968480(-) A-I      intronic
chr10:101968135(-) A-I      intronic
chr10:101965515(-) A-I      intronic
chr10:101971737(-) A-I      intronic
chr10:101988378(-) A-I      intronic
chr10:101973458(-) A-I      intronic
chr10:101973119(-) A-I      intronic
chr10:101967966(-) A-I      intronic
chr10:101967892(-) A-I      intronic
chr10:101973472(-) A-I      intronic
chr10:101973482(-) A-I      intronic
chr10:101968378(-) A-I      intronic
chr10:101973417(-) A-I      intronic
chr10:101956233(-) A-I      intronic
chr10:101968114(-) A-I      intronic
chr10:101973066(-) A-I      intronic
chr10:101988404(-) A-I      intronic
chr10:101988166(-) A-I      intronic
chr10:101968136(-) A-I      intronic
chr10:101971804(-) A-I      intronic
chr10:101988167(-) A-I      intronic
chr10:101981533(-) A-I      intronic
chr10:101976384(-) A-I      intronic
chr10:101971810(-) A-I      intronic
chr10:101957562(-) A-I      intronic
chr10:101973411(-) A-I      intronic
chr10:101968393(-) A-I      intronic
chr10:101973012(-) A-I      intronic
chr10:101968118(-) A-I      intronic
chr10:101973180(-) A-I      intronic
chr10:101968028(-) A-I      intronic
chr10:101972596(-) A-I      intronic
chr10:101973346(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CHUK
chr10:101968481(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CHUK
chr10:101985771-101985772(-) m6A CDS       24209618//27371828//27773536
chr10:101989315-101989316(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989326-101989327(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989338-101989339(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989368-101989369(-) m6A 5'UTR       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30a-3p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
CHUK
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30a-3p
Sorafenib 216239 Drug interaction    RC00000903
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30a-3p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30a-3p
Interactor2: CHUK

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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