Detail Information

Basic Information:


  VIRBase ID:  

HHID00043782

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-25-3p:           C21orf91:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-25-3p C21orf91
miRBase
Accession/Entrez ID		 MIMAT0000081 54149
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C21orf14//C21orf38//CSSG1//EURL//YG81

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-25-3p
rs1377178975 chr7:100093592    G/A
rs1413158272 chr7:100093578    G/A
rs1413158272 chr7:100093578    G/C
rs1436445161 chr7:100093576    C/T
rs41274221 chr7:100093577    C/T
rs759105083 chr7:100093574    G/A
rs759105083 chr7:100093574    G/T
rs773692731 chr7:100093571    T/C
rs775442904 chr7:100093582    C/T
rs1174517921 chr7:100093587    G/T
rs1244343842 chr7:100093591    T/A
rs991454083 chr7:100093585    G/A
rs991454083 chr7:100093585    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR C21orf91
chr21:19178991(-) A-I      intronic
chr21:19178911(-) A-I      intronic
chr21:19178899(-) A-I      intronic
chr21:19167141(-) A-I      intronic
chr21:19167201(-) A-I      intronic
chr21:19173867(-) A-I      intronic
chr21:19173846(-) A-I      intronic
chr21:19167220(-) A-I      intronic
chr21:19167218(-) A-I      intronic
chr21:19188070(-) A-I      intronic
chr21:19178994(-) A-I      intronic
chr21:19167192(-) A-I      intronic
chr21:19167139(-) A-I      intronic
chr21:19188159(-) A-I      intronic
chr21:19188116(-) A-I      intronic
chr21:19188243(-) A-I      intronic
chr21:19188180(-) A-I      intronic
chr21:19188250(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase C21orf91
chr21:19165615-19165616(-) m6A 3'UTR       22608085
chr21:19165675-19165676(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr21:19165683-19165684(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr21:19165725-19165726(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr21:19165738-19165739(-) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22608085
chr21:19165766-19165767(-) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22608085
chr21:19165801-19165802(-) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22608085
chr21:19165815-19165816(-) m6A 3'UTR//CDS       24284625//24981863//27773535//22608085
chr21:19168928-19168929(-) m6A CDS       24284625//24209618//27773535//22608085
chr21:19168958-19168959(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr21:19169049-19169050(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr21:19169056-19169057(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr21:19169218-19169219(-) m6A CDS//exon       24284625//26404942//27773535//22608085
chr21:19169278-19169279(-) m6A CDS//exon       24209618//24981863//26404942//27773535//22608085
chr21:19169300-19169301(-) m6A CDS//exon       24209618//24981863//26404942//27773535//22608085
chr21:19169353-19169354(-) m6A CDS//exon       24209618//24981863//26404942//27773535//22608085
chr21:19169383-19169384(-) m6A CDS//exon       24209618//24981863//27773535//22608085
chr21:19183720-19183721(-) m6A exon//intron       27773535//22608085
chr21:19183780-19183781(-) m6A exon//intron       27773535
chr21:19190501-19190502(-) m6A exon//intron       22608085
chr21:19190550-19190551(-) m6A CDS//exon       24981863//27371828//22608085
chr21:19190562-19190563(-) m6A CDS//exon       25456834//24981863//27371828//22608085
chr21:19190569-19190570(-) m6A CDS//exon       25456834//24981863//27371828//22608085
chr21:19190609-19190610(-) m6A CDS//exon       25456834//24981863//27371828//22608085
chr21:19191196-19191197(-) m6A 5'UTR//intron       25456834//24981863//27371828//22608085
chr21:19191663-19191664(-) m6A 5'UTR//exon       25456834
chr21:19191677-19191678(-) m6A 5'UTR//exon       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-25-3p
Cytoplasm Neural progenitor cells     21363885
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Primary dendritic cells|T cell line (J77)     21505438
Exosome Renal cancer cells     21670082
Exosome Ovarian follicular fluid     22116803
Exosome Breast milk     22211110
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Human esophageal cancer cell line (EC9706)     25184951
Exosome Blood|B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Colon tissue|Endothelial cells|Epithelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Seminal fluid|Tongue tissue     -
Extracellular Vesicle Liposarcoma cell lines (Lipo224B|Lipo246|Lipo863|LPS141)|Preadipocytes     28588009
Extracellular vesicle Plasma     32498409
Extracellular vesicle HEK-293T cells     22849433
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Hepatoma cells     23771658
Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Colon adenocarcinoma cells     20864815
C21orf91
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-25-3p
Iodine Green 9956454 Drug sensitive
Sensorad 99342 Drug sensitive
2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive
Actinomycin X4357G methoxime 9573583 Drug sensitive
Tiotixene 941651 Drug sensitive
Dichlorodipropylstannane 93562 Drug sensitive
(3Z,8S,11Z,16S)-8,16-Bis(2-oxopropyl)-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetrone 92973777 Drug sensitive
2,5-Dimethyl-1,4-benzoquinone 8718 Drug sensitive
4-(2-Pyridylazo)-N,N-dimethylaniline 81528 Drug sensitive
L-2-Aminobutyric acid 80283 Drug sensitive
Vancide 26 79411 Drug sensitive
2,4,6-Tris(2-pyridyl)-s-triazine 77258 Drug sensitive
Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive
Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive
2-Butenoic acid, 2-methyl-, 2,3,3a,4,5,8,9,11a-octahydro-8-hydroxy-6-(hydroxymethyl)-10-methyl-3-methylene-2-oxocyclodeca(b)furan-4-yl ester, (3aR-(3aR*,4R*(Z),6Z,8S*,10E,11aR*))- 71586750 Drug sensitive
4,4'-Bis(dimethylamino)thiobenzophenone 71045 Drug sensitive
Tolonium chloride 7083 Drug sensitive
Sulbentine 67686 Drug sensitive
Silver mesylate 6712944 Drug sensitive
2-Debenzoyl-2-(3',5'-difluorobenzoyl)-A-nortaxol 6712230 Drug sensitive
Acnistin F 6712173 Drug sensitive
Reactive Blue 2 656725 Drug sensitive
(2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive
Ixabepilone 6445540 Drug sensitive
Vicenistatin 6438888 Drug sensitive
Verrucarin A 6326658 Drug sensitive
Piriqualone 6015423 Drug sensitive
trans-1,2-Bis(propylsulfonyl)ethylene 5904452 Drug sensitive
1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive
Liatris laevigata lactone #2 5477810 Drug sensitive
8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive
Caracemide 54747 Drug sensitive
Thiopyrimidine-CH3 5473238 Drug sensitive
Iejimalide A. 5473233 Drug sensitive
Artelasticin 5471311 Drug sensitive
Antineoplastic-690266 5469577 Drug sensitive
(Z)-1-Iodo-2-phenyl-1-penten-3-one 5468684 Drug sensitive
(Z)-4-Bromo-4-iodo-3-phenylbut-3-en-2-one 5467656 Drug sensitive
6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive
3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive
Withacnistin 54606507 Drug sensitive
Antineoplastic-651590 54604785 Drug sensitive
Selendale 54601159 Drug resistant
(1S,2R,4R,7E,9R)-9-Hydroxy-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one 54600951 Drug sensitive
Aspiculamycin hcl 54600418 Drug resistant
Herveline O 5459269 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Methyl (1R,4R,7E,9S,10R,11S)-9-acetyloxy-10-(2,3-dimethyloxirane-2-carbonyl)oxy-4-methyl-12-methylidene-13-oxo-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-ene-8-carboxylate 5458601 Drug sensitive
Thiram 5455 Drug sensitive
Simvastatin 54454 Drug resistant
(E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive
Melampodin B acetate 5359212 Drug sensitive
Ovatifolin acetate 5358419 Drug sensitive
Rozex 5353923 Drug sensitive
Indanthren Corinth RK 5351878 Drug sensitive
5-Bromo-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329234 Drug sensitive
5-Methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 Drug sensitive
Herbimycin 5311102 Drug sensitive
Vorinostat 5311 Drug sensitive
Pyrethrosin 5281496 Drug sensitive
Erioflorin acetate 5281443 Drug sensitive
8-Hydroxymanzamine A 5270765 Drug sensitive
Kekule 499328 Drug sensitive
Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498558 Drug sensitive
Lychnopholide 49767028 Drug sensitive
6-Methoxy-7-(2lambda(5)-1,2-triazadienyl)-5,8-quinolinedione 494043 Drug sensitive
Tiazofurin 457954 Drug sensitive
N-Methyl-1,5-bis(4-cyanophenoxy)-3-aza-pentane 45028719 Drug sensitive
BAS100 Monohydrate 45028404 Drug sensitive
4-(5'-Bromofuran-2'-yl)-3-bromo-but-3-en-2-one 45028185 Drug sensitive
1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive
[(1R,2S,3S,5R,6R,8S,10E,12R,13S,15R,16S,17R,18S)-18-Benzyl-6-hydroxy-6,8,15,16-tetramethyl-7,20-dioxo-4,14-dioxa-19-azapentacyclo[10.8.0.01,17.03,5.013,15]icos-10-en-2-yl] acetate 44559501 Drug sensitive
Oxyacanthine 442333 Drug sensitive
Elephantopin 442206 Drug sensitive
1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive
Isobrucein A 441802 Drug sensitive
Ditercalinium dimethanesulfonate dimethanesulfonate 435243 Drug sensitive
2,6-Epoxy-2H-1-benzoxocin-5(6H)-one, 6,8-dimethyl- 434882 Drug sensitive
Oridonin (thiol adduct OF) 432952 Drug sensitive
Di-n-octyl-secalonsaure A 430141 Drug sensitive
Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide 42640 Drug sensitive
Cyano pyridine-P-CH3 406496 Drug sensitive
S-(Dimethylarsino)-3-mercapto-1,2-propyl dibenzoate 406481 Drug sensitive
S-(Dimethylarsino)-3-mercapto-1,2-propyl dinonanoate 406480 Drug sensitive
S-(Dimethylarsino)-3-mercapto-1,2-propyl diacetate 406479 Drug sensitive
S-(Diisopropylarsino)-3-mercapto-1,2-propanediol 406478 Drug sensitive
Aminopyrimidine-CH3 406278 Drug sensitive
Nanaomycin A 40586 Drug sensitive
Ethanone, 1-[3-(bromomethyl)-1,4-dioxido-2-quinoxalinyl]- 404859 Drug sensitive
2-[(Phenylamino)methyl]benzene-1,4-diol 403336 Drug sensitive
Triacetyl crambescidin 800 hydrochloride 400721 Drug sensitive
Artelastin 399488 Drug sensitive
Phosphine, 1,2-ethanediylbis[bis[2-(methylthio)phenyl]- 397601 Drug sensitive
Sjg-136 393111 Drug sensitive
2,4-Diamino-7-(4-chloroanilino)methylpteridine 393101 Drug resistant
2-Amino-4-(2-hydroxy-4-methylphenyl)-5-phenylpyrimidine 392744 Drug sensitive
3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant
1,3-Diphenyl-6-((triphenylphosphoranylidene)amino)-2,4(1H,3H)-pyrimidinedione 387460 Drug sensitive
Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive
N-(2-Bromo-5-methoxybenzylidene)-6,7-dimethoxy-1-naphthalenamine 387181 Drug sensitive
L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive
4-Phenacyloxychromen-2-one 386272 Drug resistant
2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive
Stereoisomer of NSC 674066-O 384359 Drug sensitive
(-)7,8-Dihydrocalanolide A 383107 Drug sensitive
2-Chloro-3-(1-(4-methyl)piperazino)naphthazarin 378627 Drug sensitive
2-Amino-5,8-dihydroxy-1,4-naphthoquinone 377209 Drug sensitive
(1R)-3,3-Dibromocamphor 376765 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
Cycloalkannin 375418 Drug sensitive
3,8-Dimethyl-1,2-naphthoquinone 373912 Drug sensitive
4-Methylthio-N-(3,4,5-trimethoxybenzyl)aniline 373808 Drug sensitive
N-Hydroxy-N-methylpropanethioamide 371713 Drug sensitive
Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant
Antineoplastic-645804 371505 Drug sensitive
11H-Benzo[a]carbazole-1,4-dione, 7,11-dimethyl- 371271 Drug sensitive
Sanguilutine pseudobase 371258 Drug sensitive
1-(4-Methoxy-2-methylphenyl)naphtho[1,2-c]furan-3(1H)-one 369148 Drug sensitive
(4-Methoxyphenyl)-(3,4,5-trimethoxyphenyl)methanol 368140 Drug sensitive
4-(1-Benzofuran-2-yl)-7-methoxychromen-2-one 364364 Drug resistant
4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive
3-Nitro-5-formylisoxazole 362479 Drug sensitive
Aplidazole C . TFA 362402 Drug sensitive
Discorhabdin C . TFA 362393 Drug sensitive
4H-1-Benzothiopyran-4-one, 2-(methylsulfinyl)- 360259 Drug sensitive
Thiosangivamycin 3580213 Drug sensitive
1-Chloro-3-(3-chloropropylsulfonylsulfanyl)propane 355643 Drug sensitive
Bis(helenalinyl)glutarate 336831 Drug sensitive
4-Selenazolecarboxamide, 2-beta-D-ribofuranosyl- 334706 Drug sensitive
Predorine 333830 Drug sensitive
Rocaglamide 331783 Drug sensitive
Helenin 327378 Drug sensitive
Rustaiyan A 324967 Drug sensitive
Dmask 32465 Drug sensitive
2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive
1,4-Naphthalenedione, 5,8-dihydroxy-2,3-bis(hydroxymethyl)- 313371 Drug sensitive
2-Chloro-3-(dodecylsulfanyl)-5,6-dimethoxycyclohexa-2,5-diene-1,4-dione 312122 Drug sensitive
6-(Dimethylarsanylsulfanylmethyl)oxane-2,3,4,5-tetrol 311912 Drug sensitive
Bromocriptine 31101 Drug sensitive
Stannane, trimethyl[(4-morpholinylthioxomethyl)thio]- 300936 Drug sensitive
[(5Z)-1,7,7-Trimethyl-5-(nitromethylene)-6-oxo-norbornan-2-yl] acetate 3004516 Drug sensitive
2,3-Bis(iodomethyl)-6-methoxyquinoxaline 286257 Drug sensitive
(3Ar,4r,4as,8r,8ar,9as)-8-hydroxy-8a-methyl-3,5-dimethylidene-2-oxododecahydronaphtho[2,3-b]furan-4-yl acetate 279214 Drug sensitive
(15S)-15-Ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one 2724040 Drug sensitive
1H-Benzo[a]carbazole-1,4(11H)-dione, 11-methyl- 261066 Drug sensitive
Hydrazine sulfate 24842 Drug sensitive
Antimycin A3 245869 Drug sensitive
5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive
1-(3-Bromo-phenyl)-3-(pyridin-2-ylsulfanyl)-propenone 24203485 Drug sensitive
6-(Hexynyl)-2(2H)-pyranone 24203137 Drug sensitive
(2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive
[(4E,6Z,10Z)-20,22-Dihydroxy-13,14,17-trimethoxy-4,8,10,12,16-pentamethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-9-yl] carbamate 24199492 Drug sensitive
Prumycin HCl 24197905 Drug resistant
CID 24197685 24197685 Drug sensitive
Antibiotic U 29135 24196291 Drug sensitive
7-Fluoro-2-benzoyl-3-trifluoromethylquioxaline 1,4-dioxide 23635154 Drug sensitive
1-(2-(Dimethylamino)ethyl)-3-(((2R,4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl)methyl)urea 23634407 Drug sensitive
4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive
Drostanolone propionate 224004 Drug sensitive
(1S,3R,7Z,9R,12S,13R,15R)-13-Hydroxy-3,7,12-trimethyl-13-prop-1-en-2-yl-10,14,16-trioxatetracyclo[7.5.1.13,6.012,15]hexadeca-5,7-diene-4,11-dione 20835084 Drug sensitive
Nile Blue 2B 20520 Drug sensitive
Methyl 1,6,8,14a-tetrahydroxy-11-[(4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl)amino]-6a-methoxy-3-methyl-7,9,12,14-tetraoxo-5,6-dihydrobenzo[a]tetracene-2-carboxylate 197261 Drug sensitive
8-Hydroxyquinoline 1923 Drug sensitive
Sudan II 18386 Drug sensitive
4-Chloro-5-(pyridin-2-ylthio)-3H-1,2-dithiole-3-thione 16766538 Drug sensitive
4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive
2,2-Diethyl-6-(hydroxymethyl)-4,6,7,7a-tetrahydro-3aH-[1,3,2]dioxastannolo[4,5-c]pyran-4,7-diol 16683462 Drug sensitive
4H-1,3,2-Benzodioxastannin-4-one, 7-amino-2,2-diphenyl- 16683127 Drug sensitive
Trihexyltetradecylphosphonium hexafluorophosphate 16212610 Drug sensitive
Butyltriphenylphosphonium bromide 159628 Drug sensitive
Antineoplastic-633273 15954131 Drug sensitive
(3As,3bR)-3b-hydroxy-3a,5,5-trimethyl-3-methylidene-4H-cyclopenta[a]pentalene-2,6-dione 15699597 Drug sensitive
(6R)-1,6,11-Trihydroxy-8-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-3-methyl-5,6-dihydrobenzo[a]anthracene-7,12-dione 15507920 Drug sensitive
(2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive
[(1S,2R,3R,4R,6S,8S,9R,10S,11S,13R)-2,8-Diacetyloxy-3,6-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 153274253 Drug sensitive
Methyl 3,4-dichloro-5-nitro-2-furoate 147711 Drug sensitive
4-Oxo-4-[[(13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid 146160078 Drug sensitive
1H-2,10a-Ethanophenanthrene, kaur-16-en-15-one deriv. 146156727 Drug sensitive
Methyl 3-bromo-2-(bromomethyl)propionate 140895 Drug sensitive
Methyl (7E,9Z,11R,12S,13R,14R,15R,17R,18S,19S,20E)-2,16-diacetyloxy-12,14,18,19,31-pentahydroxy-3,7,11,13,17,19,21,27-octamethyl-6,28-dioxo-23,25-dioxa-5-azatetracyclo[20.7.1.14,29.026,30]hentriaconta-1,3,7,9,20,22(30),26,29(31)-octaene-15-carboxylate 138319083 Drug sensitive
Astrazon Orange R 135747272 Drug sensitive
Acid Alizarine Red B 135565636 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
Emofolin sodium 135475347 Drug sensitive
2-Chloro-3-(2-butoxyethoxy)naphthazarin 135406263 Drug sensitive
Inosine dialdehyde 135400916 Drug sensitive
(1R,2S,5S,8S,9S,17R,18R,21S,24R,26S,27S)-14-Chloro-5,15-dihydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacos-11-ene-4,10,22,29-tetrone 134715214 Drug sensitive
Dibutyltin dichloride 12688 Drug sensitive
15-Deacetylsergeolide 125729 Drug sensitive
Triphenyltin chloride 12540 Drug sensitive
(2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive
2-Chloro-3-(phenylsulfonyl)propanenitrile 121458 Drug sensitive
Melampodinin 11953936 Drug sensitive
Unii-C616DV5Y11 117587576 Drug sensitive
Cyanoaminopyranopyridine derivatives 11494577 Drug resistant
p-Toluquinone 11122 Drug sensitive
Gentian violet 11057 Drug sensitive
Acetylenedicarboxamide 10971 Drug sensitive
Unii-9JU14BJ5QG 109374088 Drug sensitive
Cladospirone bisepoxide 10316810 Drug sensitive
Fusariotoxin T-2 102515111 Drug sensitive
15,16-Dihydrocuracin A 101683509 Drug sensitive
(1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive
Erigerol 101318126 Drug sensitive
(1S,3R,6R,12S,14R,15S,18R,19E,21Z,25R,26S,27R)-6,15-Dihydroxy-18-[(1R)-1-hydroxyethyl]-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione 101307863 Drug sensitive
Chimaphilin 101211 Drug sensitive
6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant
pyrazino[1,2-a]benzimidazole, 1,3-diphenyl- - Drug resistant
geldanamycin dimethylglycinate - Drug resistant
tgf.alpha.-pe40 - Drug resistant
tp4ek - Drug resistant
(1s,2e,4r,7e,11e)-4-hydroxy-2,7,11-cembratrien-6-one - Drug sensitive
(1s,2e,4s,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug sensitive
(2r,3r)-(+)-methyl 3-phenyloxirane-carboxylate - Drug sensitive
(E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-5-(3-methyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole - Drug sensitive
(z) 2',3,4,5-tetramethoxystilbene - Drug sensitive
(z) 3,3',4,5-tetramethoxystilbene - Drug sensitive
(Z)-3-((1-(3,5-dimethoxyphenyl)-9H-pyrido[3,4-b]indol-3-yl)methylene)-5-methoxyindolin-2-one - Drug sensitive
(Z)-5-methoxy-3-((1-(3,4,5-trimethoxyphenyl)-9H-pyrido[3,4-b]indol-3-yl)methylene)indolin-2-one - Drug sensitive
1,2,3-thiadiazole, 5-[(4-chlorophenyl)sulfonyl]-4-phenyl- - Drug sensitive
1,2-naphthoquinone, 3,7-dimethyl- - Drug sensitive
1,3-butadiene, 1,1,2,4,4-pentachloro-3-nitro- - Drug sensitive
1,4-anthracenedione, 5-hydroxy- - Drug sensitive
1,4-benzenediamine (9ci), n-butyl-n'-phenyl- - Drug sensitive
1,6,7,8-tetra-o-phenylcarbamoylcastnospermine - Drug sensitive
1,8-naphthyridin-4(1h)-one, 2-(3-chlorophenyl)-5-methyl- - Drug sensitive
1h-1,4,7-triazonine-1,4-diacetic acid, octahydro- - Drug sensitive
1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive
1h-benzo[a]carbazole-1,4(11h)-dione, 11-phenyl- - Drug sensitive
1-piperidinecarbodithioic acid, antimony complex - Drug sensitive
2-(n,n-diethyl)acetyl-1,2-dihydroellipticine - Drug sensitive
2,2',5,5'-tetrahydroxy-4,4'-dimethylbiphenyl - Drug sensitive
2,3,4-tri-o-acetyl-1-s-dimethylarsino-1-thio- a -d-xylose - Drug sensitive
2,6-bis(4-morpholinylmethyl)cyclohexanone,dihydrochloride - Drug sensitive
2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive
2-azabicyclo[16.3.1]docosane, geldanamycin deriv. - Drug sensitive
2-bromo-5,8-dihydroxy-3-methyl-1,4-naphthoquinone - Drug sensitive
2h-naphtho[1,2-b]pyran-2-one, 9-hydroxy-4-phenyl- - Drug sensitive
3,19-(4-n,n-dimethylamino)benzylidineandrographolide - Drug sensitive
3,3'-diamino-4,4'-bis(dimethylamino)benzophenone - Drug sensitive
4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive
4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive
4-morpholinecarbodithioic acid, antimony complex - Drug sensitive
4-quinazolone, 7-amino-3-(4-methoxyphenyl)-, hydrate - Drug sensitive
4-thiomorpholinecarbodithioic acid, antimony complex - Drug sensitive
5,6,7,8-tetrafluoronaphtho[2,3-c][1,2,5]thiadiazole-4,9-dione - Drug sensitive
5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug sensitive
5-[2-(4-methoxyphenyl)ethyl]-1,2,3-dimethoxy benzene - Drug sensitive
7-n,n-dimethylamino brefeldin a hydrochloride - Drug sensitive
9h-purine, 2-amino-6-(2,4-dichlorobenzylthio)-9-isobutyl- - Drug sensitive
anthracen-9-one, 10-[(2-methoxyphenyl)methylene]- - Drug sensitive
b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive
benzamide, 5-bromo-2-hydroxy-n-[3-(trifluoromethyl)phenyl]- - Drug sensitive
benzene, 1,1'-[(1,3-butadiene-1,4-diyl)sulfonyl]bis - Drug sensitive
benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive
benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive
benzofurazan, 5-nitro-6-(1-piperidinyl)-, 1-oxide - Drug sensitive
c4, carbonyl, ethyl prodigiosine - Drug sensitive
cyclohexanone, 2,6-bis(piperidinomethyl)- - Drug sensitive
cyclopentanone, 2,5-bis[(trimethylamino)methyl]-, iodide - Drug sensitive
dichloro(dodeca-2,6,10-triene-1,12-diyl)- ruthenium - Drug sensitive
dimethylarsinothious acid, 2,4-pyrimidinediyl ester - Drug sensitive
E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive
ellipticine, 6-(3-aminopropyl)-, dihydrochloride - Drug sensitive
geldanamycin, n,n'-dimethyl - Drug sensitive
gold(1+), bis(trimethylphosphine)-, chloride - Drug sensitive
indoline, 5-chloro-1,3,3-trimethyl-2-methylene- (8ci) - Drug sensitive
iodonium, (4-methoxyphenyl)(3-methylphenyl)-, bromide - Drug sensitive
isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive
phosphonium, (3-bromopropyl)triphenyl- bromide - Drug sensitive
piperazine-2,2,5,5-tetracarbonitrile, 3,6-dipropyl- - Drug sensitive
roridin a, 8-hydroxy-9b,10b-epoxy- - Drug sensitive
salicylaldehyde, 5-bromo- (8ci) - Drug sensitive
tricyclo[4.4.0.0(2,7)]decane-5-one, 4,4-dibromo-2-methyl- - Drug sensitive
uracil, 1-[1,2-bis(ethoxycarbonyl)ethenyl]-, cis- - Drug sensitive
uridine, 5-isobutyl-2'-deoxy- - Drug sensitive
(Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
(Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
[bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive
1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive
2-amino-5-chloro-6-(2-thiazolyloxy)-benzimidazole - Drug sensitive
4-carbo-1-thiazolidine-3-o-gluconyl-.gamma.-lactone - Drug sensitive
5-hydroxyamino camptothecin - Drug sensitive
9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive
antibiotic a54556 - Drug sensitive
antineoplastic-615538 - Drug sensitive
aromoline - Drug sensitive
arylmethylene-f - Drug sensitive
bavachyaone - Drug sensitive
Carboxyphthalatoplatinum - Drug sensitive
chlorambucil-spermidine - Drug sensitive
chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive
Copper(II) complex with a thiosemicarbazone as a ligand - Drug sensitive
cyclo [n-naphthoyl-d-lys-asn-gln-trp-ala-val-d-ala-his-leu] - Drug sensitive
dichlorobisoxinatotitanium(iv) - Drug sensitive
geldanamycin analog - Drug sensitive
his 47-methyl ct - Drug sensitive
hyperforinacetate - Drug sensitive
isatin dr - Drug sensitive
kaurane deriv - Drug sensitive
leucinostatine d - Drug sensitive
n-acetyl-4-s-cystaminyl phenol - Drug sensitive
n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive
phenylmercuric acetate (usan) - Drug sensitive
streptorubrin - Drug sensitive
Tetraplatin - Drug sensitive
thiadiazines - Drug sensitive
Uniroyal Compound-38 - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-25-3p
Curcumin 969516 Drug interaction    RC00000754
Formaldehyde 712 Drug interaction    RC00000734
Ethanol 702 Drug interaction    RC00000733
Isoliquiritigenin 638278 Drug interaction    RC00000753
Colchicine 6167 Drug interaction    RC00000741
Gemcitabine 60750 Drug interaction    RC00000747
Vincristine 5978 Drug interaction    RC00000740
Eloxatine 5310940 Drug interaction    RC00000756
Imatinib 5291 Drug interaction    RC00000739
Cyclosporin A 5284373 Drug interaction    RC00000755
Decitabine 451668 Drug interaction    RC00000752
Diethylstilbestrol 448537 Drug interaction    RC00000751
Trichostatin A 444732 Drug interaction    RC00000750
Epirubicin 41867 Drug interaction    RC00000746
Etoposide 36462 Drug interaction    RC00000745
Paclitaxel 36314 Drug interaction    RC00000744
5-Fluorouracil 3385 Drug interaction    RC00000738
Doxorubicin 31703 Drug interaction    RC00000743
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00000737
Verapamil 2520 Drug interaction    RC00000736
Benzo[a]pyrene 2336 Drug interaction    RC00000735
2,3,7,8-Tetrachlorodibenzo-P-dioxin 15625 Drug interaction    RC00000742
Docetaxel 148124 Drug interaction    RC00000749
Ginsenoside Rh2 119307 Drug interaction    RC00000748
Marine fungal metabolite 1386A - Drug interaction    RC00000759
Chemotherapy - Drug interaction    RC00008821
5-aza-2'-deoxycytidine (5-Aza-CdR) + trichostatin A(TSA) - Drug interaction    RC00000758
1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00000757
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-25-3p
Paclitaxel 36314       26323677

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-25-3p
Interactor2: C21orf91

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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