Detail Information

Basic Information:


  VIRBase ID:  

HHID00038889

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      LINC00672:           hsa-miR-548w:      

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Interactor Information:


Interactor1 Interactor2
Symbol LINC00672 hsa-miR-548w
miRBase
Accession/Entrez ID		 100505576 MIMAT0015060
Organism Homo sapiens Homo sapiens
Category lncRNA miRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548w
rs1217191628 chr16:26025268    T/C
rs1247960808 chr16:26025262    T/C
rs1299975801 chr16:26025261    T/C
rs1331351492 chr16:26025258    G/A
rs768527810 chr16:26025257    C/T
rs918935898 chr16:26025246    A/G
rs925963272 chr16:26025259    G/A
rs1232952112 chr16:26025252    A/C
rs1355338018 chr16:26025250    GTAAC/G
rs573018690 chr16:26025249    A/G

RNA Editing:


Resource Symbol Editing Position
Lncediting LINC00672
    chr17: 37084302
    chr17: 37084137

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LINC00672
chr17:37082733-37082734(+) m6A exon       25456834
chr17:37082754-37082755(+) m6A exon       25456834
chr17:37082811-37082812(+) m6A exon       25456834
chr17:37082828-37082829(+) m6A exon       25456834
chr17:37082877-37082878(+) m6A exon       -
chr17:37082896-37082897(+) m6A exon       -
chr17:37082919-37082920(+) m6A exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate LINC00672
Exosome Blood     -
hsa-miR-548w
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug LINC00672
1-O-(3-O-beta-D-Glucopyranosylbutyryl)pancratistatin       398556
(9-Hydroxy-10-oxo-10H-indeno[1,2-b]indol-5-yl)-acetic acid       24205927
Nutlin-3       216345
(S)-N-((S)-1-Cyclohexyl-2-oxo-2-((3aR,7aS)-6-phenethyloctahydro-1H-pyrrolo[2,3-c]pyridin-1-yl)ethyl)-2-(methylamino)propanamide       11503417
benzenethiol, methyl-, mercury(2+) salt       -

Interaction Network (The top 100 interactions):


Interactor1: LINC00672
Interactor2: hsa-miR-548w

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA
Support Database ViRBase

References:


PMID 31199512 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line 293 cells//C2089 cells//C22 cells Interactor2 expression None
Description Figure 5 Target genes of the EBV-related lncRNAs. Online software program search results demonstrated that four lncRNAs target two common genes, FUS and U2AF65; three lncRNAs commonly target UPF1; and five lncRNAs target one common gene, eIF4AIII, as indicated in the red boxes. Interactions were also predicted between lncRNAs and miRNAs.

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