Basic Information:
VIRBase ID:
HHID00038855
Virus:
Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)
Host:
Homo sapiens
Confidence Score:
0.7311
Interaction Type:
Host-Host interaction
Interactor Information:
|
Interactor1 |
Interactor2 |
Symbol |
MIR3936HG |
CDK4 |
miRBase Accession/Entrez ID |
553103 |
1019 |
Organism |
Homo sapiens |
Homo sapiens |
Category |
lncRNA |
protein |
Alias |
SLC22A5-AS1
|
CMM3//PSK-J3
|
RNA Editing:
Resource |
Symbol |
Editing Position |
Lncediting |
MIR3936HG |
|
Resource |
Symbol |
Editing Position |
Change |
Genetic Region |
RADAR |
CDK4 |
|
Resource |
Symbol |
Editing Position |
Change |
SeqReg |
exReg |
PMID |
DARNED |
CDK4 |
|
RNA Modification:
Resource |
Symbol |
ModificationPosition |
Type |
Genomic Context |
PMID |
RMBase |
CDK4 |
|
RNA Localization:
Resource |
Symbol |
Subcellular Localization |
Tissue or Cell Line |
PMID |
RNALocate |
CDK4 |
|
Interaction Network (The top 100 interactions):
Interactor1: MIR3936HG |
|
Interactor2: CDK4 |
|
Evidence Support:
Strong-Evidence |
Western blot |
Support Database |
ViRBase
|
References:
PMID |
32306460 |
Target region |
None |
Source |
ViRBase
|
Interactor1 expression |
Downregulation |
Tissue or cell line |
5-8F cells//AGS cells//C666-1 cells//HNE2 cells |
Interactor2 expression |
None |
Description |
Knockdown of LOC553103 resulted in increased p27 expression and decreased CCNE1, CCND1, and CDK4 expression as shown by western blotting (Figure 3B). |