Basic Information:

  VIRBase ID:  

HHID00038694

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      MALAT1:  NR_144568          hsa-miR-200a-3p:  MIMAT0000682     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	MALAT1	hsa-miR-200a-3p
miRBase Accession/Entrez ID	378938	MIMAT0000682
Organism	Homo sapiens	Homo sapiens
Category	lncRNA	miRNA
Alias	HCN//LINC00047//NCRNA00047//NEAT2//PRO2853	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-200a-3p	rs1011167625 chr1:1167924    T/C rs1219797994 chr1:1167926    T/A rs376377337 chr1:1167932    C/A rs376377337 chr1:1167932    C/T rs746361624 chr1:1167930    A/G rs1301032989 chr1:1167923    G/T rs1377467792 chr1:1167920    A/G rs749623182 chr1:1167920    ACTGT/A

RNA Editing:

Resource	Symbol	Editing Position
Lncediting	MALAT1	chr11: 65273328     chr11: 65273630     chr11: 65269316

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MALAT1	chr11:65273328(+) A-I      ncRNA chr11:65269316(+) A-I      ncRNA chr11:65273630(+) A-I      ncRNA

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MALAT1	chr11:65268358(+) A-I intron -    22327324 chr11:65268662(+) A-I intron -    22327324 chr11:65268829(+) A-I intron -    22327324 chr11:65268863(+) A-I intron -    22327324 chr11:65269100(+) A-I intron -    22327324 chr11:65269102(+) A-I intron -    22327324 chr11:65269316(+) A-I intron -    22327324 chr11:65269321(+) A-I intron -    22327324 chr11:65269667(+) A-I intron -    22327324 chr11:65270102(+) A-I intron -    22327324 chr11:65270147(+) A-I intron -    22327324 chr11:65270472(+) A-I intron -    22327324 chr11:65271236(+) A-I intron -    22327324 chr11:65271256(+) A-I intron -    22327324 chr11:65271381(+) A-I intron -    22327324 chr11:65271563(+) A-I intron -    22327324 chr11:65271566(+) A-I intron -    22327324 chr11:65272270(+) A-I intron -    22327324 chr11:65272294(+) A-I intron -    22327324 chr11:65272297(+) A-I intron -    22327324 chr11:65272325(+) A-I intron -    22327324 chr11:65272340(+) A-I intron -    22327324 chr11:65272589(+) A-I intron -    22327324 chr11:65272859(+) A-I intron -    22327324 chr11:65273033(+) A-I intron -    22327324 chr11:65273037(+) A-I intron -    22327324 chr11:65273038(+) A-I intron -    22327324 chr11:65273039(+) A-I intron -    22327324 chr11:65273041(+) A-I intron -    22327324 chr11:65273068(+) A-I intron -    22327324 chr11:65273328(+) A-I intron -    22327324 chr11:65273630(+) A-T intron -    21725310   //22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MALAT1	chr11:65266574-65266575(+) m6A exon       24209618//24981863//26404942//27773535//22575960//22608085 chr11:65266719-65266720(+) m6A exon       24209618//24981863//27773535//22575960//22608085 chr11:65266765-65266766(+) m6A exon       24981863//27773535//22575960//22608085 chr11:65266836-65266837(+) m6A exon//intron       24981863//27773535//22575960//22608085 chr11:65266903-65266904(+) m6A exon//intron       24981863//27773535//22575960//22608085 chr11:65266976-65266977(+) m6A exon//intron       24981863//27773535//22575960//22608085 chr11:65266994-65266995(+) m6A exon//intron       24981863//27773535//22575960//22608085 chr11:65267101-65267102(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267135-65267136(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267143-65267144(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267147-65267148(+) Am exon//intron       - chr11:65267202-65267203(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267234-65267235(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267264-65267265(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267276-65267277(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267303-65267304(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267329-65267330(+) m6A exon//intron       24981863//28052920//26404942//27773535//22575960//22608085 chr11:65267380-65267381(+) m6A exon//intron       24981863//26404942//27773535//22575960//22608085 chr11:65267390-65267391(+) m6A exon//intron       24981863//26404942//27773535//22575960//22608085 chr11:65267567-65267568(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:65267573-65267574(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:65267645-65267646(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:65267665-65267666(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:65267746-65267747(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:65267808-65267809(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:65267842-65267843(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr11:65267905-65267906(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085 chr11:65267915-65267916(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085 chr11:65267929-65267930(+) m6A exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr11:65267951-65267952(+) m6A exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr11:65267987-65267988(+) Am exon//intron       - chr11:65268041-65268042(+) m1A exon//intron       26863196 chr11:65268189-65268190(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:65268274-65268275(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960 chr11:65268437-65268438(+) m6A exon       24209618//24981863//26404942//27773535//22575960 chr11:65268508-65268509(+) m6A exon       24209618//26404942//27773535//22575960 chr11:65268536-65268537(+) m6A exon       24209618//26404942//27773535 chr11:65268605-65268606(+) Y exon       26075521 chr11:65268751-65268752(+) Y exon       25219674 chr11:65268794-65268795(+) m6A exon       24981863//26404942//27773535 chr11:65268823-65268824(+) m6A exon       24981863//26404942//27773535 chr11:65268850-65268851(+) m6A exon       24981863//26404942//27773535 chr11:65268944-65268945(+) m6A exon       24981863//26404942//27773535 chr11:65268969-65268970(+) m6A exon       24981863//26404942//27773535 chr11:65269084-65269085(+) m6A exon       24981863//26404942//27773535//22575960 chr11:65269126-65269127(+) m6A exon       24981863//26404942//27773535//22575960 chr11:65269138-65269139(+) m6A exon       24981863//26404942//27773535//22575960 chr11:65269234-65269235(+) m6A exon       24981863//26404942//27773535//22575960 chr11:65269410-65269411(+) m6A exon       26404942//27773535//22575960 chr11:65269424-65269425(+) m6A exon       26404942//27773535//22575960 chr11:65269653-65269654(+) m6A exon       26404942//22575960 chr11:65269781-65269782(+) m6A exon       26404942//22575960 chr11:65269793-65269794(+) m6A exon       26404942//22575960 chr11:65269944-65269945(+) m6A exon//intron       26404942 chr11:65269993-65269994(+) m6A exon//intron       26404942 chr11:65270088-65270089(+) m6A exon//intron       26404942 chr11:65270107-65270108(+) m6A exon//intron       26404942 chr11:65270175-65270176(+) m6A exon//intron       24981863//26404942//27773535//22575960//22608085 chr11:65270275-65270276(+) m6A exon//intron       24981863//26404942//27773535//22575960//22608085 chr11:65270391-65270392(+) Y exon       25219674//25192136//26075521 chr11:65270587-65270588(+) m6A exon//intron       24981863//26404942//27773535//22575960 chr11:65270641-65270642(+) m6A exon//intron       26404942 chr11:65270821-65270822(+) Y exon       25219674//25192136//26075521 chr11:65270825-65270826(+) m6A exon//intron       26404942 chr11:65271054-65271055(+) m6A exon//intron       26404942//27773535 chr11:65271079-65271080(+) m6A exon//intron       26404942//27773535 chr11:65271201-65271202(+) m6A exon//intron       26404942//27773535 chr11:65271214-65271215(+) m6A exon//intron       26404942//27773535 chr11:65271228-65271229(+) m6A exon//intron       26404942//27773535 chr11:65271279-65271280(+) m6A exon//intron       26404942//27773535//22575960 chr11:65271372-65271373(+) m6A exon//intron       26404942//27773535 chr11:65271690-65271691(+) m6A exon//intron       26404942 chr11:65271796-65271797(+) m6A exon       26404942 chr11:65272104-65272105(+) m6A exon//intron       26404942//22575960 chr11:65272155-65272156(+) m6A exon//intron       26404942 chr11:65272164-65272165(+) m6A exon//intron       26404942 chr11:65272190-65272191(+) m6A exon//intron       26404942 chr11:65272212-65272213(+) m6A exon//intron       26404942 chr11:65272292-65272293(+) m6A exon       26404942//27773535 chr11:65272303-65272304(+) m6A exon       26404942//27773535 chr11:65272334-65272335(+) m6A exon       26404942 chr11:65272371-65272372(+) m6A exon       26404942 chr11:65272376-65272377(+) m6A exon       26404942 chr11:65272405-65272406(+) m6A exon       26404942 chr11:65272436-65272437(+) m6A exon       26404942//27773535 chr11:65272472-65272473(+) m6A exon       26404942//27773535 chr11:65272486-65272487(+) m6A exon       26404942//27773535 chr11:65272494-65272495(+) m6A exon//intron       26404942//27773535 chr11:65272539-65272540(+) m6A exon//intron       26404942//27773535 chr11:65272594-65272595(+) m6A exon//intron       26404942 chr11:65272694-65272695(+) m6A exon//intron       26404942 chr11:65272725-65272726(+) m6A exon//intron       26404942 chr11:65272794-65272795(+) m6A exon//intron       26404942 chr11:65273061-65273062(+) m6A exon//intron       26404942//22575960 chr11:65273166-65273167(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273223-65273224(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273268-65273269(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273278-65273279(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273309-65273310(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273328-65273329(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273343-65273344(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273361-65273362(+) Tm exon//intron       - chr11:65273412-65273413(+) m6A exon//intron       26404942//22575960 chr11:65273426-65273427(+) m6A exon//intron       26404942//22575960 chr11:65273435-65273436(+) m6A exon//intron       26404942//22575960 chr11:65273518-65273519(+) m6A exon//intron       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MALAT1	Chromatin Breast cancer cell line (SKBR3)     28652379 Chromatin HeLa-S3 cells|K562 cells     - Cytoplasm HEK-293T cells|Mammary epithelium cell line (HC11)     31863590 Cytoplasm Lung cancer cell lines (A549|H1299)     34012919 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Thyroid papillary carcinoma cell line (TPC-1)     29967342 Exosome HeLa cells     24205503 Exosome Serum     - Insoluble cytoplasm K562 cells     - Membrane HCC cell line (HepG2)|K562 cells     - Mitochondrion HCC cell line (HepG2)     31218107 Nuclear speckle Breast cancer cell line (MCF-7)     28652379 Nuclear speckle Retinal microvascular endothelial cells     30815547 Nuclear speckle U2OS cells     31085639 Nuclear speckle HEK-293T cells|Mammary epithelium cell line (HC11)     31863590 Nuclear speckle HeLa-TO cells     22355166 Nucleolus K562 cells     - Nucleoplasm WI-38 cells     29133588 Nucleoplasm K562 cells     - Nucleus Human osteosarcoma cell line (U2OS)     28423669 Nucleus HeLa cells     28663102 Nucleus WI-38 cells     29133588 Nucleus Human brain microvascular endothelial cells     30419554 Nucleus Human cervical cancer cell line (HeLa)     28216671 Nucleus U2OS cells     28538188 Nucleus Breast cancer cell lines (MDA-MB-468|SKBR3)     28652379 Nucleus HeLa cells     29335281 Nucleus Lung cancer cell line (A549)     30548064 Nucleus Vascular smooth muscle cells     31696492 Nucleus Fibroblasts|Lymphoblasts     17270048 Nucleus Cell line (HeLa)     19041754 Nucleus HeLa cells     20797886 Nucleus Motor neurons     22070123 Nucleus Human cervical cancer cell line (HeLa)     22078878 Nucleus HeLa cells     22855529 Nucleus HeLa cells     23073843 Nucleus Cell line (HeLa)     23152763 Nucleus Colon cancer cells     24393600 Nucleus HeLa cells     25630241 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Speckle periphery HeLa cells|WI-38 cells     29133588
	hsa-miR-200a-3p	Exosome Human milk     28688106 Exosome Pulmonary epithelial cell line (BEAS-2B)     31520698 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Ascites fluid|Pleural effusion     21601258 Exosome Breast milk     22211110 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Breast milk|Colon tissue|Seminal fluid|Tongue tissue     - Microvesicle Seminal plasma     23539611 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Nucleus Colon adenocarcinoma cells     20864815

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-200a-3p	Gardenin B 96539 Drug sensitive 2-(Benzyloxy)-4-methoxybenzaldehyde 820527 Drug resistant 1H-Pyrazolo[3,4-d]pyrimidin-4-amine 75420 Drug sensitive 10,11-Methylenedioxy-20S-camptothecin 72403 Drug resistant Coptisine chloride 72321 Drug resistant 4H-Furo(3,2-g)(1)benzopyran-4,7,9-trione 68083 Drug resistant 4'-Chloro-3-hydroxy-2'-methyl-2-naphthanilide 66718 Drug resistant Fludarabine 657237 Drug resistant Mevastatin 64715 Drug resistant Mastoparan 6324633 Drug resistant Irinotecan 60838 Drug resistant Gemcitabine 60750 Drug resistant Topotecan 60700 Drug resistant 3-[4-(1H-Indol-3-yl)-1,3-thiazol-2-yl]-1-methyl-1H-indole 60147979 Drug sensitive Cisplatin 5702198 Drug resistant Thiopyrimidine-CH3 5473238 Drug sensitive (Z)-3-Iodo-1,2-diphenyl-2-propen-1-one 5468683 Drug sensitive 2-trans-n-Buten-1-yl-estradiol 5468334 Drug resistant (8R,9S,13S,14S,17S)-13-Methyl-2-[(E)-prop-1-enyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 5468270 Drug resistant Selendale 54601159 Drug resistant Aspiculamycin hcl 54600418 Drug resistant Simvastatin 54454 Drug resistant 2-Methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol 5386397 Drug resistant Xestin A 5352066 Drug sensitive 3-[(4-Methoxyphenyl)thio]-2H-isoindole-1-carbaldehyde 53361730 Drug sensitive Lovastatin 53232 Drug resistant Centaureidin 5315773 Drug resistant 8-Hydroxymanzamine A 5270765 Drug sensitive Methoxycamptothecin 494089 Drug resistant SMA-838 (HCl salt of NSC 188491) 45028430 Drug sensitive Ditercalinium dimethanesulfonate dimethanesulfonate 435243 Drug sensitive Carboplatin 426756 Drug resistant Diaziquone 42616 Drug resistant cis-Diamminemalonatoplatinum(II) 422683 Drug resistant Mitoxantrone 4212 Drug resistant Menadione 4055 Drug resistant Fagaronine chloride 40304 Drug resistant 1,2 Benzo-8-(1-hydroxy-2-methylamino propane)-3-phenoxazone 400530 Drug resistant 3,3-Bis[4-(4-aminoiphenoxy)phenyl]diamantane 399961 Drug sensitive 1H-Indole, 5-bromo-3-[2-(2-pyridinyl)-4-thiazolyl]- 397551 Drug sensitive 1-(4'-Phthalimidopropyl-carbonyl)-5-fluorouracil 388985 Drug sensitive Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug resistant Stereoisomer of NSC 674066-O 384359 Drug sensitive 2-Ethenyl estradiol 381026 Drug resistant Antineoplastic-655905 375758 Drug resistant 1,2-Dimethyl-phenothiazone 369387 Drug resistant Diselenide, bis(4-methylphenyl) 365239 Drug resistant Miltefosine 3599 Drug sensitive 4-N,N-Bis-2'-cyanoethylaminobenzylidene-4-fluoro aniline 359414 Drug sensitive 2-Benzoylaminobenzamide, N-thiazol-2-yl- 355710 Drug sensitive 5-Fluorocytosine arabinoside 352938 Drug resistant Nordracorubin 341882 Drug sensitive Phomazarin 318385 Drug resistant Tamoxifen 2733526 Drug sensitive Chlorambucil 2708 Drug resistant Chelerythrine 2703 Drug sensitive 1-(2-Chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea 26328 Drug resistant Estramustine 259331 Drug resistant Fluorene, 9-bromo-2,4,7-trichloro- 248608 Drug resistant Camptothecin 24360 Drug resistant Scillirosidin, glycoside 222160 Drug resistant 5-Nitroso-8-hydroxyquinoline 19103 Drug resistant {4-[5-(4-Fluoro-phenyl)-3-(1-methyl-piperidin-4-yl)-3H-imidazol-4-yl]-pyrimidin-2-yl}-phenyl-amine 17892742 Drug sensitive 8-Chloroadenosine 147569 Drug sensitive 4-Oxo-4-[[(13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid 146160078 Drug sensitive Edelfosine 1392 Drug sensitive Gold;(2S,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxane-2-thiolate;triethylphosphanium 138402869 Drug resistant Oxanthrazole 135502299 Drug resistant 8-Azahypoxanthine 135410720 Drug resistant 8-Azaguanine 135403646 Drug resistant Triphenyltin chloride 12540 Drug sensitive Dabequine 124332 Drug sensitive 2,2'-Bioxirane 11254 Drug resistant Clomesone 100651 Drug resistant N,N-Bis(2-chloroethyl)-p-toluidine 100400 Drug resistant 1,3,6-triphenyl-oxazolo(5,4-d)pyrimidin-2',4(1h,3h)-dion - Drug resistant 1h-1,2,4-triazole, 3-(4-diazo-4h-imidazol-5-yl)- - Drug resistant benzo[1,2-b:4,5-b']dithiophene-4,8-diol, diacetate - Drug resistant benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate - Drug resistant benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug resistant bersaldegenin 1,3,5-orthoacetate - Drug resistant mercury, tetrakis(acetato)(2,3,4,5-thiophenetetrayl)tetra- - Drug resistant naphth[2,3-d]oxazol-9-one, 2-methyl-4-(phenylimino)- - Drug resistant naphtho[2,3-d]oxazole-4,9-dione, 2-(1,1-dimethylethyl)- - Drug resistant phosphinic acid, bis(1-aziridinyl)-, 2-naphthyl ester - Drug resistant piceatannol, 4,3',5'-trimethyl,1s0 - Drug resistant tris(1,3-diphenylpropane-1,3-dionata)gallium(iii) - Drug resistant 2-(n-d-glysoyl)aminobenzothiazole - Drug resistant 3-farnesylthiopropionamide - Drug resistant Camptothecin Derivative - Drug resistant Chlorozotocin - Drug resistant CI-921: amsacrine derivative - Drug resistant crotoxin cd - Drug resistant potassium arsenite - Drug resistant potassium[trichloro(isopropylamine)platinum] - Drug resistant protein toxin a 23 - mw approx. 6700 - Drug resistant protein toxin c 10 - mw approx. 6700 - Drug resistant trimethyl(phenylthio)stannane - Drug resistant (E)-3-(3,5-dimethoxyphenyl)-1-(4-(quinazolin-4-ylamino)phenyl)prop-2-en-1-one - Drug sensitive uridine, 5-fluoro-, 2',3',5'-triacetate - Drug sensitive Artemisinin Dimer - Drug sensitive pyrazoline derivative - Drug sensitive secafascaplysin - Drug sensitive streptorubrin - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	MALAT1	Vincristine 5978 Drug interaction    RC00000036
	hsa-miR-200a-3p	N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide 9826528 Drug interaction    RC00003889 10-Hydroxycamptothecin 97226 Drug interaction    RC00003881 Curcumin 969516 Drug interaction    RC00003886 Hydrogen peroxide 784 Drug interaction    RC00003868 Gemcitabine 60750 Drug interaction    RC00003880 Vincristine 5978 Drug interaction    RC00003876 Estradiol 5757 Drug interaction    RC00003875 RETINOIC ACID, 13-cis- 5538 Drug interaction    RC00003885 Eloxatine 5310940 Drug interaction    RC00003888 Goserelinacetate 47725 Drug interaction    RC00003879 Paclitaxel 36314 Drug interaction    RC00003878 5-Fluorouracil 3385 Drug interaction    RC00003874 Doxorubicin 31703 Drug interaction    RC00003877 Cyclophosphamide 2907 Drug interaction    RC00003873 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00003872 Tamoxifen 2733526 Drug interaction    RC00003887 Verapamil 2520 Drug interaction    RC00003871 Bicalutamide 2375 Drug interaction    RC00003870 Benzo[a]pyrene 2336 Drug interaction    RC00003869 Erlotinib 176870 Drug interaction    RC00003884 Docetaxel 148124 Drug interaction    RC00003883 Gefitinib 123631 Drug interaction    RC00003882 Epoxomicin 11226684 Drug interaction    RC00003890 1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00003891 Chemotherapy - Drug interaction    RC00008851

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-200a-3p	Cisplatin 5702198       25356050 5-Fluorouracil 3385       28496200

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	MALAT1	6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile       9956119 Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride       9938202 Rucaparib       9931954 1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054 Tivozanib       9911830 Zibotentan       9910224 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786 PI-103       9884685 Osi-930       9868037 5Z-7-Oxozeaenol       9863776 2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine       9858940 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol       984170 Midostaurin       9829523 N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide       9826528 8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acid       92577 1,9-Pyrazoloanthrone       8515 Phenformin       8249 (E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one       78243717 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide       71271629 N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473 (S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848 Panobinostat       6918837 Belinostat       6918638 2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide       6918454 Temsirolimus       6918289 Daporinad       6914657 N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167 AICA ribonucleotide       65110 Tanespimycin       6505803 Ispinesib mesylate       6450816 Axitinib       6450551 Pelitinib       6445562 Piperlongumine       637858 Cytarabine       6253 Gemcitabine       60750 Mitomycin       5746 5-[2-[4-(Aminomethyl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2-chlorophenol;hydrochloride       57399803 1-[4-[4-Amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea;hydrochloride       57391096 (2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)       57339144 1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea       56962337 Dimethyloxalylglycine       560326 l-685,458       5479543 Austocystin D       5470400 2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid       54685215 Temozolomide       5394 1-Piperidineethanol, alpha-[p-(p-chlorostyryl)phenyl]-       5351150 N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664 Palbociclib       5330286 Bosutinib       5328940 Vorinostat       5311 Bryostatin 1       5280757 2-Morpholino-6-(thianthren-1-yl)-4H-pyran-4-one       5278396 Bis(2-hydroxy-1-naphthyl) disulfide       521106 2-{[4-(5-Ethylpyrimidin-4-Yl)piperazin-1-Yl]methyl}-5-(Trifluoromethyl)-1h-Benzimidazole       51371303 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide       5113032 Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine       498558 Tubastatin A       49850262 Alectinib       49806720 2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432 (S)-(+)-Tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate       46907787 3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626 Avagacestat       46883536 2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine       46224516 N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454 Epothilone B       448013 N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912 1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660 Tretinoin       444795 Dabrafenib       44462760 Refametinib       44182295 Foretinib       42642645 Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide       42640 (2S)-2-[[2-(2,3-Dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol       42623900 Mercury, chloro-2-naphthalenyl-       425433 Janus Red B       407803 Benzenamine, 4-(5,6-difluoro-2-benzothiazolyl)-2-methyl-       400168 4-N-(3-Bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine;methanesulfonic acid       382058 Arborescidine D       378619 Etoposide       36462 3,4-Dihydroxynaphthalene-2-carboxylic acid       356138 5-Fluorouracil       3385 N6-Benzyladenosine-5'-phosphate       318601 AT 116, benzylamine salt       282523 Tamoxifen       2733526 [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965 2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557 Ruxolitinib       25126798 Cabozantinib       25102847 Navitoclax       24978538 MK-2206       24964624 Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314 Quizartinib       24889392 Ponatinib       24826799 Vismodegib       24776445 4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860 Cudc-101       24756910 Vincaleukoblastine       241903 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide       24180719 Bicalutamide       2375 Olaparib       23725625 (2E,5E)-2,5-Bis(thiophen-2-ylmethylene)cyclopentanone       2314623 Nutlin-3       216345 Lenalidomide       216326 Enzastaurin       176167 4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide       16747388 Gsk-690693       16725726 Fedratinib       16722836 3-[(1-Methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one       16219401 N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin-4-yl)ethoxy]benzamide       16095342 1-(Tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea       1401 (Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062 (E)-5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime       135421339 Pac-1       135421197 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one       135418940 Osi-027       135398516 Dovitinib       135398510 Akt inhibitor VIII       135398501 Methotrexate       126941 Lestaurtinib       126565 Gefitinib       123631 Dactolisib       11977753 Veliparib       11960529 BAY 61-3606 dihydrochloride       11784504 N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511 Trametinib       11707110 Motesanib       11667893 4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372 4-[2-(2-Chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide       11634725 Idelalisib       11625818 JNK Inhibitor VIII       11624601 5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559 Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1)       11507964 5-(2-Phenylpyrazolo[1,5-A]pyridin-3-YL)-1H-pyrazolo[3,4-C]pyridazin-3-amine       11493598 Linifanib       11485656 N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846 4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide       11338033 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one       11327430 Pararosaniline hydrochloride       11292 Amuvatinib       11282283 (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667 7-Ethyl-10-hydroxycamptothecin       104842 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4h-Chromen-3-Yl 3,4-Di-O-Acetyl-6-Deoxy-alpha-L-Mannopyranoside       10459196 VX-702       10341154 Afatinib       10184653 Selumetinib       10127622 Pazopanib       10113978 N-(3-{[5-Iodo-4-({3-[(Thiophen-2-Ylcarbonyl)amino]propyl}amino)pyrimidin-2-Yl]amino}phenyl)pyrrolidine-1-Carboxamide       10077147 Masitinib       10074640 25-Dihydrosaframycin A       100180 Basic Fuchsin       - Bleomycin (50 uM)       - Cetuximab       - Cisplatin       - Cobimetinib (isomer 1)       - [co(me2dtc)2(dee)]clo4       - copper(ii) ocetanedioate 1,10-phenanthroline perchlorate       - Genentech Cpd 10       - JQ12       - JW-7-24-1       - KIN001-236       - KIN001-244       - KIN001-260       - KIN001-266       - KIN001-270       - MPS-1-IN-1       - NPK76-II-72-1       - Nutlin-3a (-)       - QL-X-138       - QL-XI-92       - rhodium dimer       - rTRAIL       - SB52334       - THZ-2-102-1       - THZ-2-49       - TL-1-85       - TL-2-105       - Tyrothricin       - VNLG/124       - WZ3105       - XMD13-2       - XMD14-99       - XMD15-27       -

Interaction Network (The top 100 interactions):

Interactor1: MALAT1
Interactor2: hsa-miR-200a-3p

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	DIANA
Support Database	ViRBase

References:

PMID	31199512	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	293 cells//C2089 cells//C22 cells	Interactor2 expression	None
Description	Figure 5 Target genes of the EBV-related lncRNAs. Online software program search results demonstrated that four lncRNAs target two common genes, FUS and U2AF65; three lncRNAs commonly target UPF1; and five lncRNAs target one common gene, eIF4AIII, as indicated in the red boxes. Interactions were also predicted between lncRNAs and miRNAs.