Basic Information:

  VIRBase ID:  

HHID00038686

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      MALAT1:  NR_144568          hsa-miR-154-5p:  MIMAT0000452     

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Interactor Information:

	Interactor1	Interactor2
Symbol	MALAT1	hsa-miR-154-5p
miRBase Accession/Entrez ID	378938	MIMAT0000452
Organism	Homo sapiens	Homo sapiens
Category	lncRNA	miRNA
Alias	HCN//LINC00047//NCRNA00047//NEAT2//PRO2853	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-154-5p	rs1339080441 chr14:101059785    C/T rs375213313 chr14:101059778    C/G rs375213313 chr14:101059778    C/T rs41286570 chr14:101059790    G/A rs41286570 chr14:101059790    G/C rs575922548 chr14:101059779    G/A rs770620613 chr14:101059789    C/T rs772665345 chr14:101059769    T/C

RNA Editing:

Resource	Symbol	Editing Position
Lncediting	MALAT1	chr11: 65273328     chr11: 65273630     chr11: 65269316

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MALAT1	chr11:65273328(+) A-I      ncRNA chr11:65269316(+) A-I      ncRNA chr11:65273630(+) A-I      ncRNA

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MALAT1	chr11:65268358(+) A-I intron -    22327324 chr11:65268662(+) A-I intron -    22327324 chr11:65268829(+) A-I intron -    22327324 chr11:65268863(+) A-I intron -    22327324 chr11:65269100(+) A-I intron -    22327324 chr11:65269102(+) A-I intron -    22327324 chr11:65269316(+) A-I intron -    22327324 chr11:65269321(+) A-I intron -    22327324 chr11:65269667(+) A-I intron -    22327324 chr11:65270102(+) A-I intron -    22327324 chr11:65270147(+) A-I intron -    22327324 chr11:65270472(+) A-I intron -    22327324 chr11:65271236(+) A-I intron -    22327324 chr11:65271256(+) A-I intron -    22327324 chr11:65271381(+) A-I intron -    22327324 chr11:65271563(+) A-I intron -    22327324 chr11:65271566(+) A-I intron -    22327324 chr11:65272270(+) A-I intron -    22327324 chr11:65272294(+) A-I intron -    22327324 chr11:65272297(+) A-I intron -    22327324 chr11:65272325(+) A-I intron -    22327324 chr11:65272340(+) A-I intron -    22327324 chr11:65272589(+) A-I intron -    22327324 chr11:65272859(+) A-I intron -    22327324 chr11:65273033(+) A-I intron -    22327324 chr11:65273037(+) A-I intron -    22327324 chr11:65273038(+) A-I intron -    22327324 chr11:65273039(+) A-I intron -    22327324 chr11:65273041(+) A-I intron -    22327324 chr11:65273068(+) A-I intron -    22327324 chr11:65273328(+) A-I intron -    22327324 chr11:65273630(+) A-T intron -    21725310   //22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MALAT1	chr11:65266574-65266575(+) m6A exon       24209618//24981863//26404942//27773535//22575960//22608085 chr11:65266719-65266720(+) m6A exon       24209618//24981863//27773535//22575960//22608085 chr11:65266765-65266766(+) m6A exon       24981863//27773535//22575960//22608085 chr11:65266836-65266837(+) m6A exon//intron       24981863//27773535//22575960//22608085 chr11:65266903-65266904(+) m6A exon//intron       24981863//27773535//22575960//22608085 chr11:65266976-65266977(+) m6A exon//intron       24981863//27773535//22575960//22608085 chr11:65266994-65266995(+) m6A exon//intron       24981863//27773535//22575960//22608085 chr11:65267101-65267102(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267135-65267136(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267143-65267144(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267147-65267148(+) Am exon//intron       - chr11:65267202-65267203(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267234-65267235(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267264-65267265(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267276-65267277(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267303-65267304(+) m6A exon//intron       24981863//28052920//27773535//22575960//22608085 chr11:65267329-65267330(+) m6A exon//intron       24981863//28052920//26404942//27773535//22575960//22608085 chr11:65267380-65267381(+) m6A exon//intron       24981863//26404942//27773535//22575960//22608085 chr11:65267390-65267391(+) m6A exon//intron       24981863//26404942//27773535//22575960//22608085 chr11:65267567-65267568(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:65267573-65267574(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:65267645-65267646(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:65267665-65267666(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:65267746-65267747(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:65267808-65267809(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:65267842-65267843(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr11:65267905-65267906(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085 chr11:65267915-65267916(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085 chr11:65267929-65267930(+) m6A exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr11:65267951-65267952(+) m6A exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr11:65267987-65267988(+) Am exon//intron       - chr11:65268041-65268042(+) m1A exon//intron       26863196 chr11:65268189-65268190(+) m6A exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:65268274-65268275(+) m6A exon//intron       24284625//24209618//24981863//26404942//27773535//22575960 chr11:65268437-65268438(+) m6A exon       24209618//24981863//26404942//27773535//22575960 chr11:65268508-65268509(+) m6A exon       24209618//26404942//27773535//22575960 chr11:65268536-65268537(+) m6A exon       24209618//26404942//27773535 chr11:65268605-65268606(+) Y exon       26075521 chr11:65268751-65268752(+) Y exon       25219674 chr11:65268794-65268795(+) m6A exon       24981863//26404942//27773535 chr11:65268823-65268824(+) m6A exon       24981863//26404942//27773535 chr11:65268850-65268851(+) m6A exon       24981863//26404942//27773535 chr11:65268944-65268945(+) m6A exon       24981863//26404942//27773535 chr11:65268969-65268970(+) m6A exon       24981863//26404942//27773535 chr11:65269084-65269085(+) m6A exon       24981863//26404942//27773535//22575960 chr11:65269126-65269127(+) m6A exon       24981863//26404942//27773535//22575960 chr11:65269138-65269139(+) m6A exon       24981863//26404942//27773535//22575960 chr11:65269234-65269235(+) m6A exon       24981863//26404942//27773535//22575960 chr11:65269410-65269411(+) m6A exon       26404942//27773535//22575960 chr11:65269424-65269425(+) m6A exon       26404942//27773535//22575960 chr11:65269653-65269654(+) m6A exon       26404942//22575960 chr11:65269781-65269782(+) m6A exon       26404942//22575960 chr11:65269793-65269794(+) m6A exon       26404942//22575960 chr11:65269944-65269945(+) m6A exon//intron       26404942 chr11:65269993-65269994(+) m6A exon//intron       26404942 chr11:65270088-65270089(+) m6A exon//intron       26404942 chr11:65270107-65270108(+) m6A exon//intron       26404942 chr11:65270175-65270176(+) m6A exon//intron       24981863//26404942//27773535//22575960//22608085 chr11:65270275-65270276(+) m6A exon//intron       24981863//26404942//27773535//22575960//22608085 chr11:65270391-65270392(+) Y exon       25219674//25192136//26075521 chr11:65270587-65270588(+) m6A exon//intron       24981863//26404942//27773535//22575960 chr11:65270641-65270642(+) m6A exon//intron       26404942 chr11:65270821-65270822(+) Y exon       25219674//25192136//26075521 chr11:65270825-65270826(+) m6A exon//intron       26404942 chr11:65271054-65271055(+) m6A exon//intron       26404942//27773535 chr11:65271079-65271080(+) m6A exon//intron       26404942//27773535 chr11:65271201-65271202(+) m6A exon//intron       26404942//27773535 chr11:65271214-65271215(+) m6A exon//intron       26404942//27773535 chr11:65271228-65271229(+) m6A exon//intron       26404942//27773535 chr11:65271279-65271280(+) m6A exon//intron       26404942//27773535//22575960 chr11:65271372-65271373(+) m6A exon//intron       26404942//27773535 chr11:65271690-65271691(+) m6A exon//intron       26404942 chr11:65271796-65271797(+) m6A exon       26404942 chr11:65272104-65272105(+) m6A exon//intron       26404942//22575960 chr11:65272155-65272156(+) m6A exon//intron       26404942 chr11:65272164-65272165(+) m6A exon//intron       26404942 chr11:65272190-65272191(+) m6A exon//intron       26404942 chr11:65272212-65272213(+) m6A exon//intron       26404942 chr11:65272292-65272293(+) m6A exon       26404942//27773535 chr11:65272303-65272304(+) m6A exon       26404942//27773535 chr11:65272334-65272335(+) m6A exon       26404942 chr11:65272371-65272372(+) m6A exon       26404942 chr11:65272376-65272377(+) m6A exon       26404942 chr11:65272405-65272406(+) m6A exon       26404942 chr11:65272436-65272437(+) m6A exon       26404942//27773535 chr11:65272472-65272473(+) m6A exon       26404942//27773535 chr11:65272486-65272487(+) m6A exon       26404942//27773535 chr11:65272494-65272495(+) m6A exon//intron       26404942//27773535 chr11:65272539-65272540(+) m6A exon//intron       26404942//27773535 chr11:65272594-65272595(+) m6A exon//intron       26404942 chr11:65272694-65272695(+) m6A exon//intron       26404942 chr11:65272725-65272726(+) m6A exon//intron       26404942 chr11:65272794-65272795(+) m6A exon//intron       26404942 chr11:65273061-65273062(+) m6A exon//intron       26404942//22575960 chr11:65273166-65273167(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273223-65273224(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273268-65273269(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273278-65273279(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273309-65273310(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273328-65273329(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273343-65273344(+) m6A exon//intron       26404942//27773535//22575960 chr11:65273361-65273362(+) Tm exon//intron       - chr11:65273412-65273413(+) m6A exon//intron       26404942//22575960 chr11:65273426-65273427(+) m6A exon//intron       26404942//22575960 chr11:65273435-65273436(+) m6A exon//intron       26404942//22575960 chr11:65273518-65273519(+) m6A exon//intron       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MALAT1	Chromatin Breast cancer cell line (SKBR3)     28652379 Chromatin HeLa-S3 cells|K562 cells     - Cytoplasm HEK-293T cells|Mammary epithelium cell line (HC11)     31863590 Cytoplasm Lung cancer cell lines (A549|H1299)     34012919 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Thyroid papillary carcinoma cell line (TPC-1)     29967342 Exosome HeLa cells     24205503 Exosome Serum     - Insoluble cytoplasm K562 cells     - Membrane HCC cell line (HepG2)|K562 cells     - Mitochondrion HCC cell line (HepG2)     31218107 Nuclear speckle Breast cancer cell line (MCF-7)     28652379 Nuclear speckle Retinal microvascular endothelial cells     30815547 Nuclear speckle U2OS cells     31085639 Nuclear speckle HEK-293T cells|Mammary epithelium cell line (HC11)     31863590 Nuclear speckle HeLa-TO cells     22355166 Nucleolus K562 cells     - Nucleoplasm WI-38 cells     29133588 Nucleoplasm K562 cells     - Nucleus Human osteosarcoma cell line (U2OS)     28423669 Nucleus HeLa cells     28663102 Nucleus WI-38 cells     29133588 Nucleus Human brain microvascular endothelial cells     30419554 Nucleus Human cervical cancer cell line (HeLa)     28216671 Nucleus U2OS cells     28538188 Nucleus Breast cancer cell lines (MDA-MB-468|SKBR3)     28652379 Nucleus HeLa cells     29335281 Nucleus Lung cancer cell line (A549)     30548064 Nucleus Vascular smooth muscle cells     31696492 Nucleus Fibroblasts|Lymphoblasts     17270048 Nucleus Cell line (HeLa)     19041754 Nucleus HeLa cells     20797886 Nucleus Motor neurons     22070123 Nucleus Human cervical cancer cell line (HeLa)     22078878 Nucleus HeLa cells     22855529 Nucleus HeLa cells     23073843 Nucleus Cell line (HeLa)     23152763 Nucleus Colon cancer cells     24393600 Nucleus HeLa cells     25630241 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Speckle periphery HeLa cells|WI-38 cells     29133588
	hsa-miR-154-5p	Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-154-5p	8-Aminoadenosine 96851 Drug resistant 1H-Pyrazolo[3,4-d]pyrimidin-4-amine 75420 Drug resistant Berberine iodide 72350 Drug sensitive 1,3,5-Triacryloylhexahydro-1,3,5-triazine 70397 Drug resistant 1-(2-Pyridylazo)-2-naphthol 6825 Drug resistant Silver mesylate 6712944 Drug resistant Pyrazolo[1,5-b]pyridazine deriv. 97 6539439 Drug resistant Crotonoside 65085 Drug resistant 3-[[4-[[2-(Methoxycarbonylamino)-3H-benzimidazol-5-yl]oxy]phenyl]carbamoylamino]benzoic acid;hydrochloride 57399799 Drug sensitive 2-Azaadenine 5480214 Drug resistant Antibiotic 1907-VIII 5477807 Drug sensitive 2-(1,3-Benzodioxol-5-yl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one 5466137 Drug sensitive [(1H-Benzimidazole-2-yl)dithio]-9H-purine 54613148 Drug resistant Varacin trifluoroacetate salt 54611558 Drug resistant 2-Methylolivacinium acetate 5458752 Drug sensitive Xestin A 5352066 Drug resistant Berberal 5351462 Drug sensitive 5-Methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 Drug sensitive Vorinostat 5311 Drug resistant 6-Bromosangivamycin 470030 Drug resistant Justicidin B 442882 Drug resistant Suavedol 442245 Drug resistant Musennin 441933 Drug sensitive Isobrucein A 441802 Drug sensitive Antibiotic X-14766A 434840 Drug sensitive Elliptinium acetate 42722 Drug sensitive 2-N-Methyl-6-thiaellipticinum iodide 367888 Drug sensitive 2-Hydroxy discorhabdin D 362391 Drug resistant 1,1-Dioxido-1,5-benzothiazepin-4-yl methyl ether 358940 Drug resistant Haloprogin 3561 Drug resistant Maxima isoflavone D 343081 Drug sensitive Ellipticine 3213 Drug sensitive 8-Trichloromethyldihydroberberine 320713 Drug sensitive 2-(2-(Diethylamino)ethyl)-9-hydroxy-5,11-dimethyl-6H-pyrido(4,3-b)carbazolium acetate 3086131 Drug sensitive 4,6-Diamino-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile 300567 Drug resistant Sarcoviolin 24202820 Drug sensitive Sodium 2-(4-((7-chloro-2-quinoxalinyl)oxy)phenoxy)propionate 23675947 Drug sensitive Kinetin riboside 20345 Drug resistant (R)-(2,8-Bis(trifluoromethyl)quinolin-4-yl)((S)-piperidin-2-yl)methanol hydrochloride 18660697 Drug resistant Paucin 161538 Drug resistant [(1R,2R,4R,6E,9R,10S)-2,7-Dimethyl-5,8,14-trioxo-10-prop-1-en-2-yl-15-oxatricyclo[11.2.1.02,4]hexadeca-6,13(16)-dien-9-yl] acetate 15384977 Drug resistant (1S,3R,5R,9R,10R)-5-Ethenyl-2,3,9,10-tetrahydroxy-5,11,11-trimethyl-16-oxatetracyclo[7.5.2.01,10.02,7]hexadec-6-en-8-one 139587002 Drug resistant Methyl ester prodigiosene 136040158 Drug resistant Acid Alizarine Red B 135565636 Drug sensitive Oxanthrazole 135502299 Drug sensitive Formycin b 135449281 Drug resistant Salicylidene salicylhydrazide 135445765 Drug resistant 43-Dioxypectenotoxin 131751434 Drug sensitive (2Z)-3-Ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methylprop-2-enylidene]-1,3-benzothiazole;hydroiodide 129893658 Drug sensitive Berberine chloride 12456 Drug sensitive Litmomycin 12310334 Drug resistant 3-Bromo-4-(3,3-dimethyl-but-1-ynyl)-2(5H)-furanone 11413833 Drug resistant 2-N-Methyl-6-oxaellipticinium acetate 10018975 Drug sensitive 1,6:2,3-dianhydro-4-o-benzyl-.beta.-d-mannopyranose - Drug resistant ethyl, methoxy, prodigisine - Drug resistant inosine, 6-thio-, 2',3',5'-tripentanoate - Drug resistant 1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant granatomycin a - Drug resistant o-linoleoyl-2-butoxy-1-desoamine - Drug resistant naphtho[1,2-b]quinolizinium, 9-methyl-, bromide - Drug sensitive phosphinic acid, bis(1-aziridinyl)-, 2-naphthyl ester - Drug sensitive phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) - Drug sensitive 2-(4-hydroxy-benzylidene)-2-(2-pyridyl)acetonitrile - Drug sensitive 2-methylellpticinium - Drug sensitive protein: pahiv4 - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	MALAT1	Vincristine 5978 Drug interaction    RC00000036
	hsa-miR-154-5p	Gemcitabine 60750 Drug interaction    RC00003199 Doxorubicin 31703 Drug interaction    RC00003198 Verapamil 2520 Drug interaction    RC00003197 1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00003200

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	MALAT1	6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile       9956119 Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride       9938202 Rucaparib       9931954 1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054 Tivozanib       9911830 Zibotentan       9910224 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786 PI-103       9884685 Osi-930       9868037 5Z-7-Oxozeaenol       9863776 2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine       9858940 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol       984170 Midostaurin       9829523 N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide       9826528 8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acid       92577 1,9-Pyrazoloanthrone       8515 Phenformin       8249 (E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one       78243717 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide       71271629 N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473 (S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848 Panobinostat       6918837 Belinostat       6918638 2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide       6918454 Temsirolimus       6918289 Daporinad       6914657 N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167 AICA ribonucleotide       65110 Tanespimycin       6505803 Ispinesib mesylate       6450816 Axitinib       6450551 Pelitinib       6445562 Piperlongumine       637858 Cytarabine       6253 Gemcitabine       60750 Mitomycin       5746 5-[2-[4-(Aminomethyl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2-chlorophenol;hydrochloride       57399803 1-[4-[4-Amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea;hydrochloride       57391096 (2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)       57339144 1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea       56962337 Dimethyloxalylglycine       560326 l-685,458       5479543 Austocystin D       5470400 2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid       54685215 Temozolomide       5394 1-Piperidineethanol, alpha-[p-(p-chlorostyryl)phenyl]-       5351150 N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664 Palbociclib       5330286 Bosutinib       5328940 Vorinostat       5311 Bryostatin 1       5280757 2-Morpholino-6-(thianthren-1-yl)-4H-pyran-4-one       5278396 Bis(2-hydroxy-1-naphthyl) disulfide       521106 2-{[4-(5-Ethylpyrimidin-4-Yl)piperazin-1-Yl]methyl}-5-(Trifluoromethyl)-1h-Benzimidazole       51371303 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide       5113032 Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine       498558 Tubastatin A       49850262 Alectinib       49806720 2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432 (S)-(+)-Tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate       46907787 3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626 Avagacestat       46883536 2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine       46224516 N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454 Epothilone B       448013 N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912 1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660 Tretinoin       444795 Dabrafenib       44462760 Refametinib       44182295 Foretinib       42642645 Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide       42640 (2S)-2-[[2-(2,3-Dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol       42623900 Mercury, chloro-2-naphthalenyl-       425433 Janus Red B       407803 Benzenamine, 4-(5,6-difluoro-2-benzothiazolyl)-2-methyl-       400168 4-N-(3-Bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine;methanesulfonic acid       382058 Arborescidine D       378619 Etoposide       36462 3,4-Dihydroxynaphthalene-2-carboxylic acid       356138 5-Fluorouracil       3385 N6-Benzyladenosine-5'-phosphate       318601 AT 116, benzylamine salt       282523 Tamoxifen       2733526 [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965 2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557 Ruxolitinib       25126798 Cabozantinib       25102847 Navitoclax       24978538 MK-2206       24964624 Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314 Quizartinib       24889392 Ponatinib       24826799 Vismodegib       24776445 4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860 Cudc-101       24756910 Vincaleukoblastine       241903 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide       24180719 Bicalutamide       2375 Olaparib       23725625 (2E,5E)-2,5-Bis(thiophen-2-ylmethylene)cyclopentanone       2314623 Nutlin-3       216345 Lenalidomide       216326 Enzastaurin       176167 4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide       16747388 Gsk-690693       16725726 Fedratinib       16722836 3-[(1-Methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one       16219401 N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin-4-yl)ethoxy]benzamide       16095342 1-(Tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea       1401 (Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062 (E)-5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime       135421339 Pac-1       135421197 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one       135418940 Osi-027       135398516 Dovitinib       135398510 Akt inhibitor VIII       135398501 Methotrexate       126941 Lestaurtinib       126565 Gefitinib       123631 Dactolisib       11977753 Veliparib       11960529 BAY 61-3606 dihydrochloride       11784504 N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511 Trametinib       11707110 Motesanib       11667893 4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372 4-[2-(2-Chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide       11634725 Idelalisib       11625818 JNK Inhibitor VIII       11624601 5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559 Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1)       11507964 5-(2-Phenylpyrazolo[1,5-A]pyridin-3-YL)-1H-pyrazolo[3,4-C]pyridazin-3-amine       11493598 Linifanib       11485656 N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846 4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide       11338033 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one       11327430 Pararosaniline hydrochloride       11292 Amuvatinib       11282283 (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667 7-Ethyl-10-hydroxycamptothecin       104842 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4h-Chromen-3-Yl 3,4-Di-O-Acetyl-6-Deoxy-alpha-L-Mannopyranoside       10459196 VX-702       10341154 Afatinib       10184653 Selumetinib       10127622 Pazopanib       10113978 N-(3-{[5-Iodo-4-({3-[(Thiophen-2-Ylcarbonyl)amino]propyl}amino)pyrimidin-2-Yl]amino}phenyl)pyrrolidine-1-Carboxamide       10077147 Masitinib       10074640 25-Dihydrosaframycin A       100180 Basic Fuchsin       - Bleomycin (50 uM)       - Cetuximab       - Cisplatin       - Cobimetinib (isomer 1)       - [co(me2dtc)2(dee)]clo4       - copper(ii) ocetanedioate 1,10-phenanthroline perchlorate       - Genentech Cpd 10       - JQ12       - JW-7-24-1       - KIN001-236       - KIN001-244       - KIN001-260       - KIN001-266       - KIN001-270       - MPS-1-IN-1       - NPK76-II-72-1       - Nutlin-3a (-)       - QL-X-138       - QL-XI-92       - rhodium dimer       - rTRAIL       - SB52334       - THZ-2-102-1       - THZ-2-49       - TL-1-85       - TL-2-105       - Tyrothricin       - VNLG/124       - WZ3105       - XMD13-2       - XMD14-99       - XMD15-27       -

Interaction Network (The top 100 interactions):

Interactor1: MALAT1
Interactor2: hsa-miR-154-5p

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	DIANA
Support Database	ViRBase

References:

PMID	31199512	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	293 cells//C2089 cells//C22 cells	Interactor2 expression	None
Description	Figure 5 Target genes of the EBV-related lncRNAs. Online software program search results demonstrated that four lncRNAs target two common genes, FUS and U2AF65; three lncRNAs commonly target UPF1; and five lncRNAs target one common gene, eIF4AIII, as indicated in the red boxes. Interactions were also predicted between lncRNAs and miRNAs.