Detail Information

Basic Information:


  VIRBase ID:  

HHID00038601

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      BCYRN1:           hsa-miR-665:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol BCYRN1 hsa-miR-665
miRBase
Accession/Entrez ID		 618 MIMAT0004952
Organism Homo sapiens Homo sapiens
Category lncRNA miRNA
Alias BC200//BC200a//LINC00004//NCRNA00004 -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-665
rs1161003917 chr14:100875086    G/A
rs1203257535 chr14:100875094    T/C
rs1251413334 chr14:100875092    C/T
rs1321122076 chr14:100875089    G/T
rs1374122857 chr14:100875088    G/A
rs759481457 chr14:100875093    C/G
rs1201625296 chr14:100875078    A/G
rs1490584325 chr14:100875079    G/C
rs747741348 chr14:100875077    C/G
rs747741348 chr14:100875077    C/T
Resource Symbol SNP ID SNP Position Ref/Alt PMID
LincSNP 3.0 BCYRN1
rs10865224 chr2:47338656 G/T         19197363
rs17036504 chr2:47340190 A/G         19875103
rs13388259 chr2:47343700 A/C         21886157
rs10514804 chr2:47336434 A/G         21886157
rs4422207 chr2:47336895 A/G         22233810

RNA Editing:


Resource Symbol Editing Position
Lncediting BCYRN1
    chr2: 47563133
    chr2: 47565123
    chr2: 47565149
    chr2: 47565158
    chr2: 47565166
    chr2: 47565181
Resource Symbol Editing Position Change Genetic Region
RADAR BCYRN1
chrX:70604430(-) A-I      intronic
chrX:70442256(-) A-I      intronic
chrX:70674220(-) A-I      intronic
chrX:70674311(-) A-I      intronic
chrX:70688453(-) A-I      intronic
chrX:70689823(-) A-I      intronic
chrX:70689824(-) A-I      intronic
chrX:70689832(-) A-I      intronic
chrX:70697339(-) A-I      intronic
chrX:70697436(-) A-I      intronic
chrX:70701085(-) A-I      intronic
chrX:70703431(-) A-I      intronic
chrX:70709469(-) A-I      intronic
chrX:70710746(-) A-I      intronic
chrX:70747192(-) A-I      intronic
chr2:47565181(+) A-I      ncRNA
chrX:70639922(-) A-I      intronic
chrX:70639925(-) A-I      intronic
chr2:47565166(+) A-I      ncRNA
chr2:47565158(+) A-I      ncRNA
chrX:70710834(-) A-I      intronic
chr2:47565149(+) A-I      ncRNA
chr2:47565123(+) A-I      ncRNA
chrX:70442253(-) A-I      intronic
chrX:70502081(-) A-I      intronic
chrX:70710842(-) A-I      intronic
chrX:70502078(-) A-I      intronic
chrX:70507309(-) A-I      intronic
chrX:70639964(-) A-I      intronic
chrX:70639969(-) A-I      intronic
chrX:70639979(-) A-I      intronic
chrX:70640455(-) A-I      intronic
chrX:70679955(-) A-I      intronic
chrX:70640516(-) A-I      intronic
chrX:70640520(-) A-I      intronic
chrX:70860365(-) A-I      intronic
chrX:70640544(-) A-I      intronic
chrX:70857567(-) A-I      intronic
chrX:70885944(-) A-I      intronic
chrX:70885948(-) A-I      intronic
chrX:70885952(-) A-I      intronic
chrX:70857557(-) A-I      intronic
chrX:70806465(-) A-I      intronic
chrX:70885985(-) A-I      intronic
chrX:70502068(-) A-I      intronic
chrX:70508325(-) A-I      intronic
chrX:70581354(-) A-I      intronic
chrX:70581357(-) A-I      intronic
chrX:70583787(-) A-I      intronic
chrX:70885943(-) A-I      intronic
chrX:70583788(-) A-I      intronic
chrX:70860366(-) A-I      intronic
chrX:70778697(-) A-I      intronic
chrX:70773168(-) A-I      intronic
chrX:70507504(-) A-I      intronic
chrX:70507320(-) A-I      intronic
chrX:70585479(-) A-I      intronic
chrX:70585483(-) A-I      intronic
chrX:70885955(-) A-I      intronic
chrX:70640521(-) A-I      intronic
chrX:70885956(-) A-I      intronic
chrX:70640497(-) A-I      intronic
chr2:47563133(+) A-I      ncRNA
chrX:70533075(-) A-I      intronic
chrX:70502123(-) A-I      intronic
chrX:70584304(-) A-I      intronic
chrX:70552143(-) A-I      intronic
chrX:70584560(-) A-I      intronic
chrX:70491204(-) A-I      intronic
chrX:70844080(-) A-I      intronic
chrX:70482863(-) A-I      intronic
chrX:70502096(-) A-I      intronic
chrX:70446233(-) A-I      intronic
chrX:70860909(-) A-I      intronic
chrX:70548699(-) A-I      intronic
chrX:70583319(-) A-I      intronic
chrX:70583324(-) A-I      intronic
chrX:70502109(-) A-I      intronic
chrX:70584568(-) A-I      intronic
chrX:70501781(-) A-I      intronic
chrX:70582087(-) A-I      intronic
chrX:70892887(-) A-I      intronic
chrX:70495938(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED BCYRN1
chrX:70484034(-) T-C intron -    22484847
chrX:70530525(-) T-C intron -    22484847
chrX:70530526(-) T-C intron -    22484847
chrX:70530900(-) T-C intron -    22484847
chrX:70538419(-) T-C intron -    22484847
chrX:70542792(-) T-C intron -    22484847
chrX:70574533(-) T-C intron -    22484847
chrX:70575001(-) T-C intron -    22484847
chrX:70575128(-) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BCYRN1
chr2:47562538-47562539(+) m6A exon       24981863
chr2:47562561-47562562(+) m6A exon       24981863
chr2:47562592-47562593(+) m6A exon       24981863
chr2:47562599-47562600(+) m6A exon       24981863
chr2:47563674-47563675(+) m6A exon       25456834//27773535
chr2:47563736-47563737(+) m6A exon       25456834//27773535
chr2:47563836-47563837(+) m6A exon       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate BCYRN1
Exosome Serum     -
hsa-miR-665
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome K562 cells     24460325
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Mesenchymal stem cells|Urine     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-665
Gemcitabine 60750 Drug interaction    RC00007441
Oxidopamine 4624 Drug interaction    RC00007440
5-Fluorouracil 3385 Drug interaction    RC00007439
Tamoxifen 2733526 Drug interaction    RC00007442
Resource Symbol Drug Name PubChem ID
RNAactDrug BCYRN1
2-(((5-(4-(4-(3-Fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)furan-2-yl)methyl)(2-(methylsulfonyl)ethyl)amino)acetonitrile       9873849
9H-Purine, 6-(ethylthio)-9-beta-D-ribofuranosyl-(8CI)(9CI)       95846
6-Benzylthioinosine       95263
Tiotixene       941651
Acridine Yellow G       8672
Sulfonaphtholazoresorcinol       85517
Benzethonium chloride       8478
3-Amino-7-(dimethylamino)-5-phenylphenazinium chloride       75442
Berberine iodide       72350
3-Hydroxy-3'-nitro-2-naphthanilide       67277
Hypopistephanine       6711179
Triciribine       65399
4-[2-(4-Fluorophenyl)-6-methylpyrazolo[1,5-b]pyridazin-3-yl]-N-phenylpyrimidin-2-amine       6539440
4-(N-Hydroxyacetamido)stilbene       6433723
Primaquine phosphate       6135
3-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol;hydrochloride       57399804
5-[2-[4-(Aminomethyl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2-chlorophenol;hydrochloride       57399803
Phyllanthastatin 1       5477587
Austocystin D       5470400
3-{(2-Carboxy-ethyl)-[4-(4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-phenyl]-amino}-propionic acid       5469598
Mito-tempol       54613387
Olivomycin Transformation       54610760
Herveline O       5459269
(10R,13R,16R,19S)-16-Butan-2-yl-3-(3-chloro-2-hydroxypropyl)-10,11,14-trimethyl-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone       5459202
1-[2-[p-[alpha-(p-Methoxyphenyl)-beta-nitrostyryl]phenoxy]ethyl]pyrrolidine citrate (1:1)       5381092
Zimeldine       5365247
Rubremetinium chloride       5351504
Chlorprothixene hydrochloride       5282478
Isotretinoin       5282379
Alsterpaullone       5005498
Phenylmethylsulfonyl fluoride       4784
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one       4713
Okadaic acid       446512
Dabrafenib       44462760
Ouabain       439501
Vemurafenib       42611257
1,6-Bis[4-(4-aminophenoxy)phenyl]diamantane       397904
Ptilomycalin A format salt       395755
9-(5-Nitropyridin-2-yl)-3H-purine-2,6-dione       389377
N, O-Diethoxyacetyl-3-demethyldeactylthiocolchicin       379556
Diisopropoxybis(1,4-naphthochinone-2-olato)titanium(IV)       368058
1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)-       362170
1,7-Diiminopyrrolo[3,4-f]isoindole-3,5-diamine       359178
3,4-Dihydroxynaphthalene-2-carboxylic acid       356138
Thymolphthalein       31316
Cytosine, 1beta-D-arabinofuranosyl-N(sup 4)-stearoyl-       304673
Clomifene citrate       3033832
AT 116, benzylamine salt       282523
(2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide       24200489
Arenaemycin E       24199350
6-Chloro-2-methoxy-9-[(5-piperidinopentyl)amino]acridine       219600
Thalicarpine       21470
Kinetin riboside       20345
Adiantifoline       167937
Mercury, (acetyloxy)(pentamethylphenyl)-       16683786
Chonemorphine       165208
Basic violet 2       14454445
N-[5-[5-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-pyridin-4-ylfuran-3-yl]-2,3-dihydroinden-1-ylidene]hydroxylamine;hydrochloride       136207967
4-[(5z)-5-(1-Nitroso-2,3-Dihydro-5h-Inden-5-Ylidene)-2-(Piperidin-4-Yl)-3,5-Dihydro-4h-Imidazol-4-Ylidene]-1,4-Dihydropyridine       136026031
Astrazon Orange R       135747272
N,N-Dimethyl-2-[4-[4-(1-nitroso-2,3-dihydroinden-5-ylidene)-5-(1H-pyridin-4-ylidene)-1H-imidazol-2-yl]phenoxy]ethanamine       135564599
Acid orange 7       135442941
Abiraterone       132971
Berberine chloride       12456
(Z)-But-2-enedioic acid;3-[4-[(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]-N-methylpropanamide       11954261
(S)-N-((S)-1-Cyclohexyl-2-oxo-2-((3aR,7aS)-6-phenethyloctahydro-1H-pyrrolo[2,3-c]pyridin-1-yl)ethyl)-2-(methylamino)propanamide       11503417
Bafetinib       11387605
Pararosaniline hydrochloride       11292
Setoglaucine       107404
[(4-Methylphenyl)methyl](triphenyl)arsanium bromide       10672721
Dequalinium chloride       10649
Saframycin A       100594
25-Dihydrosaframycin A       100180
3-pyridinecarboxamide, 6-(hydroxyazo)-, sodium salt       -
;4-fluoro-N-(3-(4-(6-(4-hydroxyphenyl)imidazo[2,1-b]thia...       -
5,6-ethylenediquino[3,2-b       -
;9-benzyl-7-benzyloxy-2-benzyl-1-methyl-9H-carbolinium b...       -
.alpha.-sarcin       -
Basic Fuchsin       -
benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate       -
benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 3-methyl-       -
benzo[b]naphtho[2,3-d]furan-6,11-dione, 4-chloro-3-hydroxy       -
bis-.mu.-propionatodiaquatetrabromorhenium(ii)       -
crotoxin cd       -
Denileukin Diftitox Ontak       -
;(E)-2-methyl-10-(3,4,5-trimethoxybenzylidene)-5-(3,4,5-...       -
gamitrinib-g4       -
gramicidin       -
g-tpp       -
Hypothemycin       -
indoline, 5-chloro-1,3,3-trimethyl-2-methylene- (8ci)       -
naphth[2,3-d]oxazol-9-one, 2-methyl-4-(phenylimino)-       -
naphtho[2,1-b]quinolizinium, 5-chloro-7-methyl- perchlorate       -
naphtho[2,3-b]furan-4,9-dione, 2-bromo-       -
N-methyl-N-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)-4-(2,6...       -
pararosaniline pamoate       -
protein toxin a 23 - mw approx. 6700       -
protein toxin b 15 - mw approx 6700       -
protein toxin c 10 - mw approx. 6700       -
rhodium dimer       -
riboprine(usan)       -
tp38-279       -
tp4ek-k6       -
tp4ek       -
Tyrothricin       -

Interaction Network (The top 100 interactions):


Interactor1: BCYRN1
Interactor2: hsa-miR-665

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA
Support Database ViRBase

References:


PMID 31199512 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line 293 cells//C2089 cells//C22 cells Interactor2 expression None
Description Figure 5 Target genes of the EBV-related lncRNAs. Online software program search results demonstrated that four lncRNAs target two common genes, FUS and U2AF65; three lncRNAs commonly target UPF1; and five lncRNAs target one common gene, eIF4AIII, as indicated in the red boxes. Interactions were also predicted between lncRNAs and miRNAs.

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