Detail Information

Basic Information:


  VIRBase ID:  

HHID00028945

  Virus:  

Gallid alphaherpesvirus 2

  Host:  

Gallus gallus

  Confidence Score:  

0.9584

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol gga-miR-26a-5p EIF3A
miRBase
Accession/Entrez ID		 MIMAT0001118 423927
Organism Gallus gallus Gallus gallus
Category miRNA mRNA
Alias - EIF3S10

Interaction Network (The top 100 interactions):


Interactor1: gga-miR-26a-5p
Interactor2: EIF3A

Evidence Support:


Strong-Evidence Luciferase reporter assay//qPCR
Weak-Evidence Deep sequencing//Microarray
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 23226446 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line 293T cells Interactor2 expression None
Description In addition, 189 putative target genes for seven differentially expressed miRNAs were predicted. The luciferase reporter gene assay showed interactions of gga-miR-181a with MYBL1, gga-miR-181a with IGF2BP3, and gga-miR-26a with EIF3A. Differential expression of miRNAs and the predicted targets strongly suggest that they contribute to MDV-induced lymphomagenesis.

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