Basic Information: VIRBase ID: HHID00026769 Virus: Anatid alphaherpesvirus 1 Host: Anas platyrhynchos Confidence Score: 0.9526 Interaction Type: Host-Host interaction
Interactor Information:
Interactor1
Interactor2
Symbol
apl-miR-30a-5p BECN1
miRBase
apl-miR-30a-5p
101792844
Organism
Anas platyrhynchos
Anas platyrhynchos
Category
miRNA
mRNA
Alias
-
-
Interaction Network (The top 100 interactions) :
Interactor1: apl-miR-30a-5p
Interactor2: BECN1
Evidence Support:
Strong-Evidence
Luciferase reporter assay//RT-qPCR//Western blot
Support Database
ViRBase
References:
PMID
31771604 Target region
3'UTR
Source
ViRBase
Interactor1 expression
Downregulation
Tissue or cell line
Duck embryo fibroblast cells
Interactor2 expression
Upregulation
Description
The miR-30a-5p was significantly downregulated and the Beclin-1 mRNA was significantly upregulated in DEV-infected DEF cells. DLRA confirmed that miR-30a-5p directly targeted the 3'- UTR of the Beclin-1 gene.
